50results about How to "Wide range of quality" patented technology

Multipole ion guides configured with one or mote segments and positioned in a higher pressure vacuum region, are operated in mass to charge selection and ion fragmentation modes. Individual multipole ion guides are mounted in a linear assembly with no electrodes configured in between each multipole ion guide. At least a portion of each multipole ion guide mounted in a linear assembly resides in a vacuum region with higher background pressure. At least one ion guide can be configured to extend continuously from one vacuum stage into another. Individual sets of RF, +/− DC and secular frequency voltage supplies provide potentials to the rods of each multipole ion guide allowing the operation of ion transmission, ion trapping, mass to charge selection and ion fragmentation functions independently in each ion guide. The presence of higher background pressure along a portion of the multiple ion guide linear assembly allows the Collisional Induced Dissociation (CID) fragmentation of ions by axially accelerating ions from one multipole ion guide to an adjacent ion guide, analogous to a triple quadrupole function. A variety of MS and MS/MSⁿ analysis functions can be achieved with a mass analyzer configured with multiple ion guide linear assembly operated in a higher background pressure.

A substrate for use in providing an ionized target comprising a structured substrate has a plurality of recesses, at least a portion of the plurality of recesses containing an initiator, the substrate being capable of having a target loaded on it. In one methods, irradiation of the substrate can cause the initiator to restructure, releasing it from the recesses and thereby desorbing and ionizing the target. The target so desorbed and ionized can be detected by mass analyzers. The mass of the targets at a given point on the surface can be recorded to provide a spatial mapping of the targets on the surface.

A tandem linear ion trap and time-of-flight mass spectrometer, where the ion trap has a straight central axis orthogonal to the flight path of the mass spectrometer. The ion trap comprises a set of electrodes, (401, 403, 402, 404) at least one of the electrodes has a slit for ejecting ions towards the mass spectrometer; a set of DC voltage supplies (+V, −V, V1, V2) to provide discrete DC levels and a number of fast electronic switches (409) for connecting/disconnecting the DC supplies to at least two of the electrodes; a neutral gas filling the ion trap and a digital controller to provide a switching procedure of ion trapping, manipulation with ions, cooling and including a state at which all ions are ejected from the ion trap towards the mass spectrometer.

A mass spectrometer capable of analyzing a wide mass range with high sensitivity and high mass accuracy. A mass spectrometer has an ionization source generating ions; an ion transfer optics transferring the ions; a first linear trap accumulating the ions and ejecting the ions in the specific mass range; a second linear trap having an end electrode disposed at the exit end ejecting the ions to change a DC potential gradient relative to a DC potential of the end electrode and trapping the ions ejected from the first linear trap to repeatedly eject them in pulse form; a time-of-flight mass spectrometer accelerating the ions ejected from the second linear trap in the orthogonal direction to detect them; and a controller changing the time duration of the ions in which the ions are ejected from the second linear trap or delay time from the completion of ejection to application of an accelerating voltage of the time-of-flight mass spectrometer according to the mass range of the ions ejected from the first linear trap to the second linear trap.

A multi reflection time of flight (MRTOF) mass spectrometer (12) And method for identifying a sample is disclosed. Sample ions are generated at an ion source (15). The MRTOF is a closed mirror arrangement with first and second opposed ion mirrors (20, 20′) on an axis of reflection (XX′). The MRTOF (12) also includes a bidirectional ion deflector (50) on that axis (XX′). The deflector (50) deflects ions onto the reflection axis as a short pulse at time to <zero> where they oscillate multiple times, separating in time of flight according to ion m/z. At a later time t, ions travelling in both directions along the axis (XX′) are ejected out of the MRTOF (12) by the bidirectional deflector (50) to an ion detector arrangement (55). The separation of ions in time of flight allows a “fingerprint” of a biological sample to be produced by the detector arrangement (55) without the need to assign a mass to each peak. Comparison with a library of fingerprints permits identification.

An ion trap comprises substantially elongate electrodes 10, 20 some of which are curved along their axis of elongation and which define a trapping volume between them. The sectional area of this trapping volume towards the extremities of the trap in the direction of elongation is different to the sectional area away from its extremities (eg towards the middle of the trap). In a preferred embodiment, the trap has a plurality of elongate electrodes, wherein opposed electrodes have different radii of curvature so that the trap splays towards its extremities. Thereby, a wider mass range of ions can be trapped and ejected, a higher space charge capacity (for a given trap length) is provided, and sharper ion beam focussing on ejection is possible.

The invention discloses a mass spectrometry method for identifying low molecular weight glutenin subunit allelic variation. The method uses matrix-assisted laser desorption-ionization time of flight mass spectrum for identifying the low molecular weight glutenin subunit and determining the allelic variation of the low molecular weight glutenin subunit according to the characteristic peak of protein. The method can be utilized for conducting accurate molecular weight determination on LMW-GS, and the standard mass spectral data of the matrix-assisted laser desorption-ionization time of flight mass spectrum (MALDI-TOF-MS) protein characteristic peak is utilized for identifying the allelic variation of LMW-GS. By the method, the molecular weight of wheat LMW-GS and the composition of LMW-GS allelic variation subunits of different types of wheat can be determined quickly and accurately, which provides powerful technological means for further research on the genetic characteristic and biochemical characteristic of LMW-GS and the contribution of LMW-GS to the processing quality of wheat, thereby laying the foundation for the intensive research on wheat seed proteome.

The invention discloses an intelligent polishing production line for putty on the surface of a casting, and belongs to the field of machining. The intelligent polishing production line comprises a robot polishing chamber, a manual finishing chamber, a spraying chamber and a drying chamber which are sequentially arranged in an assembly line, the robot polishing chamber communicates with the manualfinishing chamber through a roller type conveying line to realize material transferring, the manual trimming chamber and the spraying chamber communicate with an accumulation line through the roller type conveying line and realize material transferring, the spraying chamber communicates with the drying chamber through the roller type conveying line, a polishing robot is arranged in the robot polishing chamber and used for performing polishing on a plurality of to-be-ground positions of a workpiece, a safety optical grating for monitoring the working range of the polishing robot is further arranged in the robot polishing chamber, and an abrasive paper replacing mechanism is arranged in the robot polishing chamber and used for replacing abrasive paper on the polishing robot. According to theintelligent polishing production line for the putty on the surface of the casting, the assembly line type automatic polishing is achieved, the manpower is saved, the working efficiency is improved and the intelligent polishing production line is more environmentally friendly.

The invention discloses a precise mass spectrum method to identify wheat low-molecular-weight glutelin subunit, which comprises: (1) to prepare the sample, using 35-45% acetone to deposit protein extract and centrifuge, selecting supernatant, and using 75-85% acetone to deposit the glutelin subunit; (2) using dissolution liquid to dissolve the dissolution; wherein, the dissolution liquid comprises 15-25v% acetonitrile, 0.1v% TFA, and water.

The invention provides a method for directly detecting a multiple-PCR (Polymerase Chain Reaction) product of an influenza A virus H7N9 through mass spectrometry. The method comprises the steps of using a specific primer for carrying out multiple-PCR amplification on virus DNA (Deoxyribonucleic Acid), and detecting the size of a fragment of the multiple-PCR product through MALDI-TOF MS (Matrix-Assisted Laser Desorption/ Ionization Time of Flight Mass Spectrometry). The method can be used for detecting the H7N9 hypotype influenza A virus, and can also protect a relevant detection product. The method provided by the invention is used for clinical pathogenic microorganism identification by combining multiple-PCR and the MALDI-TOF MS, and is not only fast, simple and convenient, but also easy to observe, intuitive and high in accuracy.

The invention provides a method for directly detecting an influenza A virus multiplex PCR product by mass spectrometry. The method comprises the following steps of using a specific primer for performing multiplex PCR amplification on the virus DNA; detecting the size of the multiplex PCR product fragment through MALDI-TOF MS. The method can be used for detecting subtype influenza A viruses selected from H1N1, H3N2, H5N1 and/or H7N9 and the combination of any two kinds of viruses. Relevant detection products are also protected. By using the method, the multiplex PCR and the MALDI-TOF MS are combined to be used for clinic pathogenic microorganism identification; the advantages of high speed, simplicity, convenience, easy observation, visual effect and high accuracy are also realized.

The invention discloses a soil conditioning agent and a preparation method thereof. The soil conditioning agent comprises the following main components in percentage by weight: 90 to 96% of polyacrylamide (PAM), 1 to 3% of water soluble organic carbon (SOC), 2 to 4% of polyaspartic acid, and 1 to 3% of polyglutamic acid; the polyacrylamide (PAM) is water-in-water type anionic polyacrylamide emulsion, the molecular weight of PAM is 10,000,000 to 20,000,000, the solid content is 35 to 45%; and the water soluble organic carbon (SOC) is prepared from residues of plants. The provided soil conditioning agent can improve the physical and chemical structure of soil, increase the content of aggregates and organic matters in the soil, and enhance the water and fertilizer retaining performance of soil. Moreover, the preparation technology is simple, the production cost is low, the dissolution speed is quick, and the soil conditioning agent can be evenly applied.

The invention provides a method for directly detecting multiple PCR product of influenza A virus through a mass spectrum method. The method uses a specific primer for multiple PCR amplification on virus DNA, and is capable of detecting a fragment size of a multiple PCR product through MALDI-TOF. The method can be used for detecting H3N2 subtype influenza A virus. The method can protect the relative detection products. The method can be used for clinical pathogenic organism identification by combining with multiple PCR and a MALDI-TOF MS phase, and has the advantages of rapidity, simpleness, easy observation, direct viewing, and high accuracy.

The invention provides a method for directly detecting a multiple-PCR (Polymerase Chain Reaction) product of an influenza A virus H3N2 through mass spectrometry. The method comprises the steps of using a specific primer for carrying out multiple-PCR amplification on virus DNA (Deoxyribonucleic Acid), and detecting the size of a fragment of the multiple-PCR product through MALDI-TOF MS (Matrix-Assisted Laser Desorption/ Ionization Time of Flight Mass Spectrometry). The method can be used for detecting the H3N2 hypotype influenza A virus, and can also protect a relevant detection product. The method provided by the invention is used for clinical pathogenic microorganism identification by combining multiple-PCR and the MALDI-TOF MS, and is not only fast, simple and convenient, but also easy to observe, intuitive and high in accuracy.

The invention provides a control method of a compressor, which comprises the steps of firstly, acquiring actual current of the compressor, and determining a first output voltage based on the actual current and specified current of the compressor; then obtaining a power grid voltage, determining a second output voltage based on the first output voltage and the power grid voltage, and outputting thesecond output voltage to the compressor; secondly, comparing the first output voltage with the second output voltage to obtain a voltage difference value; and finally, determining a current change value based on the voltage difference value and a first set proportionality coefficient, and adjusting the specified current according to the current change value so as to control the actual current. Byadopting the method, the rotating speed of the compressor is prevented from suddenly decreasing or suddenly increasing when the power grid voltage is abnormal, the running stability of the compressoris improved, the working power grid quality range of an air conditioning unit is expanded, and the requirements of regions with poor electric energy quality are met.