51results about How to "Wide range of quality" patented technology

Multipole ion guides configured with one or mote segments and positioned in a higher pressure vacuum region, are operated in mass to charge selection and ion fragmentation modes. Individual multipole ion guides are mounted in a linear assembly with no electrodes configured in between each multipole ion guide. At least a portion of each multipole ion guide mounted in a linear assembly resides in a vacuum region with higher background pressure. At least one ion guide can be configured to extend continuously from one vacuum stage into another. Individual sets of RF, + / − DC and secular frequency voltage supplies provide potentials to the rods of each multipole ion guide allowing the operation of ion transmission, ion trapping, mass to charge selection and ion fragmentation functions independently in each ion guide. The presence of higher background pressure along a portion of the multiple ion guide linear assembly allows the Collisional Induced Dissociation (CID) fragmentation of ions by axially accelerating ions from one multipole ion guide to an adjacent ion guide, analogous to a triple quadrupole function. A variety of MS and MS / MSn analysis functions can be achieved with a mass analyzer configured with multiple ion guide linear assembly operated in a higher background pressure.

A substrate for use in providing an ionized target comprising a structured substrate has a plurality of recesses, at least a portion of the plurality of recesses containing an initiator, the substrate being capable of having a target loaded on it. In one methods, irradiation of the substrate can cause the initiator to restructure, releasing it from the recesses and thereby desorbing and ionizing the target. The target so desorbed and ionized can be detected by mass analyzers. The mass of the targets at a given point on the surface can be recorded to provide a spatial mapping of the targets on the surface.

A tandem linear ion trap and time-of-flight mass spectrometer, where the ion trap has a straight central axis orthogonal to the flight path of the mass spectrometer. The ion trap comprises a set of electrodes, (401, 403, 402, 404) at least one of the electrodes has a slit for ejecting ions towards the mass spectrometer; a set of DC voltage supplies (+V, −V, V1, V2) to provide discrete DC levels and a number of fast electronic switches (409) for connecting / disconnecting the DC supplies to at least two of the electrodes; a neutral gas filling the ion trap and a digital controller to provide a switching procedure of ion trapping, manipulation with ions, cooling and including a state at which all ions are ejected from the ion trap towards the mass spectrometer.

A mass spectrometer capable of analyzing a wide mass range with high sensitivity and high mass accuracy. A mass spectrometer has an ionization source generating ions; an ion transfer optics transferring the ions; a first linear trap accumulating the ions and ejecting the ions in the specific mass range; a second linear trap having an end electrode disposed at the exit end ejecting the ions to change a DC potential gradient relative to a DC potential of the end electrode and trapping the ions ejected from the first linear trap to repeatedly eject them in pulse form; a time-of-flight mass spectrometer accelerating the ions ejected from the second linear trap in the orthogonal direction to detect them; and a controller changing the time duration of the ions in which the ions are ejected from the second linear trap or delay time from the completion of ejection to application of an accelerating voltage of the time-of-flight mass spectrometer according to the mass range of the ions ejected from the first linear trap to the second linear trap.

An ion trap comprises substantially elongate electrodes 10, 20 some of which are curved along their axis of elongation and which define a trapping volume between them. The sectional area of this trapping volume towards the extremities of the trap in the direction of elongation is different to the sectional area away from its extremities (eg towards the middle of the trap). In a preferred embodiment, the trap has a plurality of elongate electrodes, wherein opposed electrodes have different radii of curvature so that the trap splays towards its extremities. Thereby, a wider mass range of ions can be trapped and ejected, a higher space charge capacity (for a given trap length) is provided, and sharper ion beam focussing on ejection is possible.

A tandem linear ion trap and time-of-flight mass spectrometer, where the ion trap has a straight central axis orthogonal to the flight path of the mass spectrometer. The ion trap comprises a set of electrodes, (401, 403, 402, 404) at least one of the electrodes has a slit for ejecting ions towards the mass spectrometer; a set of DC voltage supplies (+V, −V, V1, V2) to provide discrete DC levels and a number of fast electronic switches (409) for connecting / disconnecting the DC supplies to at least two of the electrodes; a neutral gas filling the ion trap and a digital controller to provide a switching procedure of ion trapping, manipulation with ions, cooling and including a state at which all ions are ejected from the ion trap towards the mass spectrometer.

A multi reflection time of flight (MRTOF) mass spectrometer (12) And method for identifying a sample is disclosed. Sample ions are generated at an ion source (15). The MRTOF is a closed mirror arrangement with first and second opposed ion mirrors (20, 20′) on an axis of reflection (XX′). The MRTOF (12) also includes a bidirectional ion deflector (50) on that axis (XX′). The deflector (50) deflects ions onto the reflection axis as a short pulse at time to <zero> where they oscillate multiple times, separating in time of flight according to ion m / z. At a later time t, ions travelling in both directions along the axis (XX′) are ejected out of the MRTOF (12) by the bidirectional deflector (50) to an ion detector arrangement (55). The separation of ions in time of flight allows a “fingerprint” of a biological sample to be produced by the detector arrangement (55) without the need to assign a mass to each peak. Comparison with a library of fingerprints permits identification.

The present disclosure provides a removable tap chaser for tapping an internal thread in a hole in a workpiece. The tap chaser consists of at least one carbide material and is adapted to be removably mounted on a tap system such as, for example, one of a collapsible tap system and a non-collapsible tap system.

A mass spectrometer capable of analyzing a wide mass range with high sensitivity and high mass accuracy. A mass spectrometer has an ionization source generating ions; an ion transfer optics transferring the ions; a first linear trap accumulating the ions and ejecting the ions in the specific mass range; a second linear trap having an end electrode disposed at the exit end ejecting the ions to change a DC potential gradient relative to a DC potential of the end electrode and trapping the ions ejected from the first linear trap to repeatedly eject them in pulse form; a time-of-flight mass spectrometer accelerating the ions ejected from the second linear trap in the orthogonal direction to detect them; and a controller changing the time duration of the ions in which the ions are ejected from the second linear trap or delay time from the completion of ejection to application of an accelerating voltage of the time-of-flight mass spectrometer according to the mass range of the ions ejected from the first linear trap to the second linear trap.

A multi reflection time of flight (MRTOF) mass spectrometer (12) And method for identifying a sample is disclosed. Sample ions are generated at an ion source (15). The MRTOF is a closed mirror arrangement with first and second opposed ion mirrors (20, 20′) on an axis of reflection (XX′). The MRTOF (12) also includes a bidirectional ion deflector (50) on that axis (XX′). The deflector (50) deflects ions onto the reflection axis as a short pulse at time to <zero> where they oscillate multiple times, separating in time of flight according to ion m / z. At a later time t, ions travelling in both directions along the axis (XX′) are ejected out of the MRTOF (12) by the bidirectional deflector (50) to an ion detector arrangement (55). The separation of ions in time of flight allows a “fingerprint” of a biological sample to be produced by the detector arrangement (55) without the need to assign a mass to each peak. Comparison with a library of fingerprints permits identification.

The number of times of repetition of mass spectrometry analysis for integrating mass profiles is reduced to facilitate reduction in measurement time-period and increase a signal intensity. In a state when ions are trapped by a high-frequency electric field formed within an ion trap, a rectangular-wave high-frequency voltage to be applied from a main voltage generation section to a ring electrode is temporarily stopped, and next ions are introduced from an ion entrance port into the ion trap in a state when only a static electric field exists within the ion trap. The high-frequency voltage application is re-started while at least a part of previously-trapped ions remain within the ion trap, to trap the newly-introduced ions in addition to the previous ions so as to increase an amount of ions to be accumulated, and the accumulated ions are subjected to the mass spectrometry analysis.

A time of flight mass spectrometer according to the present invention includes: a) an ion source at which an ion starts flying; b) an energizer for giving a predetermined amount of energy to the ion to let the ion start flying from the ion source; c) an ion guide for forming a time-focusing flight path on which the ion flies once or repeatedly; d) a detector for detecting the ion after flying the flight path; e) an analysis controller for giving different amounts of energy to ions of the same kind using the energizer, and for measuring the values of the flight time of the ions from the ion source to the detector for the amount of energy; and f) a mass calculator for calculating or estimating the mass to charge ratio of the ion based on the difference in the values of the flight time of the ions. Since the flight time of ions on the time-focusing flight path does not depend on their kinetic energy, the difference in the flight time of an ion having two different amounts of energy gives the estimation of the mass to charge ratio of the ion. Thus, a mass spectrometry of an ion for a wide range of mass to charge ratio can be made by simply performing two measurements on the same sample. This greatly reduces the time and labor of mass analysis, and a wide range of mass spectrum can be obtained on a scarce sample on which many-time measurements are impossible.

The invention discloses a quick vehicle-type reacting furnace which is formed by a furnace body, a furnace vehicle and an under-vehicle cooling system, wherein the furnace body comprises furnace walls and a steel structure of a furnace top and inside the furnace and is formed by a preheating section, a combustion section and a cooling section; the preheating section is provided with a purging system; the combustion section is provided with a combustion system; and the cooling section is provided with a cooling system. The quick vehicle-type reacting furnace provides a new energy-saving and environmentally-friendly path for comprehensively utilizing low-grade nickel ores. Coal derived reducing agent is added to the dried and smashed Laterite-nickel ores; ingredients are mixed evenly and then put into a kiln car container of the quick vehicle-type reacting furnace; and the reduction roasting is carried out in the quick vehicle-type reacting furnace at the temperature of 900-1350 DEG C.

An ion trap comprises substantially elongate electrodes 10, 20 some of which are curved along their axis of elongation and which define a trapping volume between them. The sectional area of this trapping volume towards the extremities of the trap in the direction of elongation is different to the sectional area away from its extremities (eg towards the middle of the trap). In a preferred embodiment, the trap has a plurality of elongate electrodes, wherein opposed electrodes have different radii of curvature so that the trap splays towards its extremities. Thereby, a wider mass range of ions can be trapped and ejected, a higher space charge capacity (for a given trap length) is provided, and sharper ion beam focussing on ejection is possible.

The invention provides an intelligent ultrasonic liquor aging system. The intelligent ultrasonic liquor aging system comprises a machine frame, a control terminal, and a plurality of sub-aging platforms; stainless-steel aging cylinders are arranged on brackets; a liquor inlet and outlet pipe is arranged on a top cover of each of the stainless-steel aging cylinders; the other end of the liquor inlet and outlet pipe is firstly connected with a sub-control liquor valve, and then, respectively connected with liquor passage pipelines; and a water inlet and outlet opening is arranged at the bottom of a stainless steel tank, and is connected with water passage pipelines. Electrically controlled valves are controlled so as to respectively realize injection of new liquor to be aged into the stainless-steel aging cylinders and discharge of duly aged liquor from the stainless-steel aging cylinders; and electrically controlled valves are controlled so as to respectively realize injection of waterinto the stainless-steel tanks and discharge of water from the stainless-steel tanks. The intelligent ultrasonic liquor aging system realizes automatic control over whole aging process with temperature and airtight condition strictly controlled, thereby effectively guaranteeing liquor aging effects and quality consistency; so that, the intelligent ultrasonic liquor aging system can be widely applied in breweries and liquor dispensers so as to shorten time to market of new liquor. In addition, the intelligent ultrasonic liquor aging system is capable of greatly improving quality of new liquor;so that, the intelligent ultrasonic liquor aging system has wide range of application scenarios.

The invention discloses a mass spectrometry method for identifying low molecular weight glutenin subunit allelic variation. The method uses matrix-assisted laser desorption-ionization time of flight mass spectrum for identifying the low molecular weight glutenin subunit and determining the allelic variation of the low molecular weight glutenin subunit according to the characteristic peak of protein. The method can be utilized for conducting accurate molecular weight determination on LMW-GS, and the standard mass spectral data of the matrix-assisted laser desorption-ionization time of flight mass spectrum (MALDI-TOF-MS) protein characteristic peak is utilized for identifying the allelic variation of LMW-GS. By the method, the molecular weight of wheat LMW-GS and the composition of LMW-GS allelic variation subunits of different types of wheat can be determined quickly and accurately, which provides powerful technological means for further research on the genetic characteristic and biochemical characteristic of LMW-GS and the contribution of LMW-GS to the processing quality of wheat, thereby laying the foundation for the intensive research on wheat seed proteome.

The invention discloses an intelligent polishing production line for putty on the surface of a casting, and belongs to the field of machining. The intelligent polishing production line comprises a robot polishing chamber, a manual finishing chamber, a spraying chamber and a drying chamber which are sequentially arranged in an assembly line, the robot polishing chamber communicates with the manualfinishing chamber through a roller type conveying line to realize material transferring, the manual trimming chamber and the spraying chamber communicate with an accumulation line through the roller type conveying line and realize material transferring, the spraying chamber communicates with the drying chamber through the roller type conveying line, a polishing robot is arranged in the robot polishing chamber and used for performing polishing on a plurality of to-be-ground positions of a workpiece, a safety optical grating for monitoring the working range of the polishing robot is further arranged in the robot polishing chamber, and an abrasive paper replacing mechanism is arranged in the robot polishing chamber and used for replacing abrasive paper on the polishing robot. According to theintelligent polishing production line for the putty on the surface of the casting, the assembly line type automatic polishing is achieved, the manpower is saved, the working efficiency is improved and the intelligent polishing production line is more environmentally friendly.

The invention discloses a precise mass spectrum method to identify wheat low-molecular-weight glutelin subunit, which comprises: (1) to prepare the sample, using 35-45% acetone to deposit protein extract and centrifuge, selecting supernatant, and using 75-85% acetone to deposit the glutelin subunit; (2) using dissolution liquid to dissolve the dissolution; wherein, the dissolution liquid comprises 15-25v% acetonitrile, 0.1v% TFA, and water.

The invention relates to a method for synthesizing glyoxylic acid by means of ozonizing maleic anhydride and mixed solvents, and belongs to the field of technologies for preparing glyoxylic acid. The method for synthesizing the glyoxylic acid by means of ozonizing the maleic anhydride and the mixed solvents is low in cost. The method includes steps of carrying out hydrolysis, ozone oxidation, reduction, reduced-pressure distillation, crystallization and the like on the inexpensive maleic anhydride in the mixed solvents to ultimately obtain glyoxylic acid solid. The method has the advantages that the glyoxylic acid solid with high purity can be directly obtained by the aid of the method, and products are high in quality and wide in application; the method is easy to implement and high in glyoxylic acid yield, the maleic anhydride can be converted into the glyoxylic acid at a low price, the method can be used for industrial large-scale production, and certain contribution can be made for solving the problem of situation of excessive maleic anhydride; optimization of the traditional processes for producing the glyoxylic acid and elimination of backward processes can be stimulated, environment-friendly oxidizing agents are adopted, and accordingly huge contribution can be made for environmental protection.

The invention provides a method for directly detecting a multiple-PCR (Polymerase Chain Reaction) product of an influenza A virus H7N9 through mass spectrometry. The method comprises the steps of using a specific primer for carrying out multiple-PCR amplification on virus DNA (Deoxyribonucleic Acid), and detecting the size of a fragment of the multiple-PCR product through MALDI-TOF MS (Matrix-Assisted Laser Desorption / Ionization Time of Flight Mass Spectrometry). The method can be used for detecting the H7N9 hypotype influenza A virus, and can also protect a relevant detection product. The method provided by the invention is used for clinical pathogenic microorganism identification by combining multiple-PCR and the MALDI-TOF MS, and is not only fast, simple and convenient, but also easy to observe, intuitive and high in accuracy.

The invention provides a method for directly detecting an influenza A virus multiplex PCR product by mass spectrometry. The method comprises the following steps of using a specific primer for performing multiplex PCR amplification on the virus DNA; detecting the size of the multiplex PCR product fragment through MALDI-TOF MS. The method can be used for detecting subtype influenza A viruses selected from H1N1, H3N2, H5N1 and / or H7N9 and the combination of any two kinds of viruses. Relevant detection products are also protected. By using the method, the multiplex PCR and the MALDI-TOF MS are combined to be used for clinic pathogenic microorganism identification; the advantages of high speed, simplicity, convenience, easy observation, visual effect and high accuracy are also realized.

The present invention provides an intelligent ultrasonic wine aging method. The intelligent ultrasonic wine aging method is characterized in that firstly starting a water injection sub-process; then starting a wine feeding sub-process; then starting a specific aging sub-process, synchronously executing a temperature control sub-process in the aging process; then starting a wine discharging sub-process; after completion, increasing judgment of whether a wine change requirement exists, if yes, starting an air washing sub-process, and if not necessary, directly performing the wine feeding sub-process to continuo aging; conducting the repeated processes and automatically performing the wine aging process. The whole aging process strictly controls temperature and is sealed, which effectively guarantees consistency of the wine aging effect and quality, whole processes of the wine feeding, wine discharging, temperature controlling, wine changing, etc. are automatically realized by checking matching states of sensors and controlling corresponding valves, and the intelligent ultrasonic wine aging method can realize automatic batch production, can be widely applied in wineries and wine sub-packaging manufacturers, shortens period of selling new wine, at the same time greatly improves quality of the new wine and has a wide application scene.

The invention discloses a soil conditioning agent and a preparation method thereof. The soil conditioning agent comprises the following main components in percentage by weight: 90 to 96% of polyacrylamide (PAM), 1 to 3% of water soluble organic carbon (SOC), 2 to 4% of polyaspartic acid, and 1 to 3% of polyglutamic acid; the polyacrylamide (PAM) is water-in-water type anionic polyacrylamide emulsion, the molecular weight of PAM is 10,000,000 to 20,000,000, the solid content is 35 to 45%; and the water soluble organic carbon (SOC) is prepared from residues of plants. The provided soil conditioning agent can improve the physical and chemical structure of soil, increase the content of aggregates and organic matters in the soil, and enhance the water and fertilizer retaining performance of soil. Moreover, the preparation technology is simple, the production cost is low, the dissolution speed is quick, and the soil conditioning agent can be evenly applied.

The invention provides a method for directly detecting multiple PCR product of influenza A virus through a mass spectrum method. The method uses a specific primer for multiple PCR amplification on virus DNA, and is capable of detecting a fragment size of a multiple PCR product through MALDI-TOF. The method can be used for detecting H3N2 subtype influenza A virus. The method can protect the relative detection products. The method can be used for clinical pathogenic organism identification by combining with multiple PCR and a MALDI-TOF MS phase, and has the advantages of rapidity, simpleness, easy observation, direct viewing, and high accuracy.

The invention relates to an electrolyte tubular reactor, which comprises reaction tube. A reaction cavity is arranged inside the reaction tube. The body of the reaction tube is slantly arranged with one end higher and the other end lower. The higher end of the reaction tube is provided with multiple raw material feeding inlets used for adding different electrolyte preparation materials, and the lower end of the reaction tube is provided with a discharge port used for discharging an electrolyte. By the adoption of the reactor of the invention, continuous production of feeding, stirring and discharging can be realized. The process time is short, batch quantity is small, and mass range of the processed electrolyte is wide. 200 kg to 20 tons of the electrolyte can be produced in the same reactor, and production residue is less. Quality stability of the product is greatly enhanced. A mixing plate inside the reactor can change speed and / or direction with a rotation shaft. Internal materials are uniformly mixed, and EC is not easy to freeze when added.

The invention provides a method for directly detecting a multiple-PCR (Polymerase Chain Reaction) product of an influenza A virus H3N2 through mass spectrometry. The method comprises the steps of using a specific primer for carrying out multiple-PCR amplification on virus DNA (Deoxyribonucleic Acid), and detecting the size of a fragment of the multiple-PCR product through MALDI-TOF MS (Matrix-Assisted Laser Desorption / Ionization Time of Flight Mass Spectrometry). The method can be used for detecting the H3N2 hypotype influenza A virus, and can also protect a relevant detection product. The method provided by the invention is used for clinical pathogenic microorganism identification by combining multiple-PCR and the MALDI-TOF MS, and is not only fast, simple and convenient, but also easy to observe, intuitive and high in accuracy.

The invention discloses a composition, a kit and a detection method for detecting gene SNP (Single Nucleotide Polymorphism) related to deafness. 20 gene polymorphic sites on different genes can be simultaneously detected in a reaction system by using a DNA sample; compared with technologies such as sequencing and real-time fluorescent quantitative PCR, the kit is lower in cost, simpler and more convenient to operate, simple and clear in map, wide in quality range and improved in accuracy and sensitivity; according to the invention, genotypes of 20 deafness gene polymorphic sites of human are detected, and the detection result is combined with other clinical indexes, so that a reference can be provided for clinicians to reasonably formulate a clinical treatment scheme, and adverse reactions are avoided; the method can be used as a supplement for an existing scheme, can enrich detection schemes of deafness-related gene polymorphic sites, and can better meet application requirements.

The invention provides a control method of a compressor, which comprises the steps of firstly, acquiring actual current of the compressor, and determining a first output voltage based on the actual current and specified current of the compressor; then obtaining a power grid voltage, determining a second output voltage based on the first output voltage and the power grid voltage, and outputting thesecond output voltage to the compressor; secondly, comparing the first output voltage with the second output voltage to obtain a voltage difference value; and finally, determining a current change value based on the voltage difference value and a first set proportionality coefficient, and adjusting the specified current according to the current change value so as to control the actual current. Byadopting the method, the rotating speed of the compressor is prevented from suddenly decreasing or suddenly increasing when the power grid voltage is abnormal, the running stability of the compressoris improved, the working power grid quality range of an air conditioning unit is expanded, and the requirements of regions with poor electric energy quality are met.