The invention discloses a method of acoustics simulated analysis and optimization for a cabin of a passenger plane. The method comprises the following steps that the cabin of the passenger plane is used as a prototype, a free meshing method is adopted based on HYPERMESH software, a cabin structure grid model containing seats is established, the cabin structure grid model is led into ANSYS in a *.cdb format, a Block Lanczos method is used for carrying out vibration mode analysis, a mode superposition method is used for carrying out harmonic response analysis, the vibration frequency response features of the cabin structure are obtained, a vibration frequency response feature destination file is led into SYSNOISE as an boundary incentives condition in a *.fre format which is capable of being recognized by the SYSNOISE, a direct boundary element method is used for finally obtaining sound pressure frequency response characteristics in the cabin, the cabin structure parameters are selected as design variables, and a lowest sound pressure order in the cabin is used as a design goal to carry out sound field optimization of civil aircraft cabins. According to the method of the acoustics simulated analysis and optimization for the cabin of the passenger plane, not only is the advantage that a finite element method is prone to obtaining vibration performance used, but also the advantage that the boundary element method obtains acoustic properties fast is brought in to full play, and therefore calculation speed is accelerated.