51 results about "Fungistatics" patented technology

The invention relates to fields of insecticides and fungal inhibitors, and concretely relates to an alga bromosesquiterpene compound, a preparation thereof and an application thereof. The concrete structural formula of the compound is represented by formula (I). The preparation method of the compound comprises the following steps: drying and crushing red alga Laurencia composita, and extracting with an organic solvent to obtain crude extracts; and carrying out silica gel column chromatography on the crude extracts, carrying out gradient elution, and separating and purifying components obtained through gradient elution with an eluent volume ratio of 15-10:1 to obtain the target compound (I). Results of insecticidal activity experiments of the bromosesquiterpene compound obtained in the invention show that the lethality of 100mug / ml of the compound to artemia is 87.7%, the median lethal concentration is 37.0mug / ml, and the compound simultaneously has a good antifungal activity.

The invention provides a fungistatic paenibacillus sp. fermentation liquor extract. The fungistatic paenibacillus sp. fermentation liquor extract is prepared through a method including the following steps that paenibacillus polymyxa CGMCC No.10062 is cultured in cow milk, and supernatant of fermentation liquor is collected. The fungistatic paenibacillus sp. fermentation liquor extract generated bypaenibacillus polymyxa is not sensitive to acid, base and temperature, has broad-spectrum and efficient fungistatic effects, and can effectively inhibit or kill pathogenic bacteria.

The invention discloses the component and content of garden plant growth regulating agent and the preparing method. The product takes growth material and biological active material of different plants as main component, and takes other component as auxiliary component. There are two kinds of agent: I. garden plant growth promoting agent and II garden plant growth delaying agent. The detail component comprises: (1) brassinolide (BR): 0.15% natural rape; (2) uniconazole (S3307): 5% ultramicroscopic wettable powder; (3) enzyme number 5; (4) biological bactericidal agent, plant se-producing germ inhibiting agent that induces plant system to get resistant effect, validamycin or polyoxin, 5- 10%; (5) pesticide progression agent, which possesses functional effects of surface activating agent, dispersing agent, stabilizing agent, spreader and anti- ultraviolet agent, 20-40%.

The present invention relates to enzymes involved in capping of fungal mRNAs, and molecules that inhibit such enzymes. In particular, the invention relates to the novel C. albicans capping enzyme genes ABD1 and CET1 and their encoded protein products, as well as derivatives and analogs thereof. The invention also relates to methods of using of fungal capping enzymes to screen for fungal inhibitors.

Disclosed is an additive of ZnO / Ag° with a bacteriostatic and fungistatic action in the production of plastic items based on resins such as polypropylene, polyethylene, polystyrene, high-impact polystyrene, polyurethanes, etc., especially for producing automotive products, electrical appliances, products for washing, for storing and conducting water, for packaging, etc. The additive is prepared by mixing nanometric silver concentrates and pre-treated zinc oxide with a polymer resin compatible with the target application as a vehicle, obtaining pellets of the additive in a ratio of between 10:90 and 90:10 in weight of ZnO / Ag° : vehicle. The additive is biologically effective at a ratio in the final product of between 0.01 and 0.5 wt. % of polymer mixture and does not have any negative effects on other properties of the polymer, such as the whiteness thereof.

The invention relates to a method for breeding fast fermentation yellow wine Saccharomyces cerevisiae, belonging to the field of microbial breeding. The method comprises the following main steps: performing pretreatment to obtain stable chemical (fungus inhibitor) resistant saccharomycetes, and screening the resistant saccharomyces to obtain the fast fermentation yellow wine Saccharomyces cerevisiae. The method is a method for screening stable chemical-resistant yellow wine Saccharomyces cerevisiae. The method can reduce the blindness brought by common screening work and improve the screening efficiency, and is of a certain guiding significance in the screening of fine saccharomyces, thereby providing important information for the breeding of yellow wine Saccharomyces cerevisiae in China.

The present invention discloses components of a resource saving chemical control product, namely a cold dosage form lawn growth regulating and controlling agent, contents of the components and a preparing method thereof. The product is prepared by mixing a plurality of plant growth substances and biological fertilizer as main contents and a plurality of other components as adjuvants. The product specifically contains the following components: (1) 10%-30% of N,N-diethylaminoethyl hexanote (code number DA-6, and trade name Defeng); (2) 10%-30% of Uniconaiole Pentefeizol Sumiseven (code number S3307) for 10%-30%; (3) 20%-50% of zymogen fertilizer which is purchased from market; (4) 5%-10% of biological fungicide which has a plant pathogenic fungal inhibitor that evokes the plant system to obtain an effect of resistance, validamycin or polyoxin; and (5) 20%-40% of herbicide synergist which is purchased from market and has multiple functions of surfactant, dispersing agent, diffusing agent, stabilizing agent, ultraviolet resisting agent, etc.

The invention provides thiosemicarbazone derivatives, a preparation method and applications thereof. The structural formula of the derivatives is represented in the description. In the formula (I), the R1 represents a fluorine atom, a chlorine atom, a bromine atom, an iodine atom, a methyl group, a methoxyl group, or a nitro group; and the R2 represents a hydrogen atom, a chlorine atom, a bromine atom, or a methyl group. The provided derivatives have a simple and novel structure, are easy to synthesize, and has a good control effect on plant pathogenic fungi. At present, the provided derivatives have not been used to prepare a plant pathogenic fungus inhibitor.

The invention discloses a gerbera piloselloides extractive, as well as a preparation method and application thereof. The gerbera piloselloides extractive is any one of A1)-A7): A1) a gerbera piloselloides 95% ethyl alcohol extractive; A2) a gerbera piloselloides petroleum ether extractant; A3) a gerbera piloselloides ethyl acetate extractant; A4) a gerbera piloselloides ethyl acetate-ligarine = 9% eluate; A5) a gerbera piloselloides ethyl acetate-ligarine = 20% eluate; A6) a gerbera piloselloides ethyl acetate-ligarine = 50% eluate; A7) a gerbera piloselloides ethyl acetate eluate. Experimental results show that the gerbera piloselloides extractive has the inhibiting effect on plant pathogenic funguses, can be directly used for inhibiting plant pathogenic funguses, and can further be used for preparing an inhibitor for plant pathogenic funguses.

The invention discloses a bitter apricot kernel essential oil extraction method. The extraction method comprises the following steps: removing grease oil from dry apricot kernels by a hot squeezing method, soaking the obtained powdery residual dregs into water with a pH value of 5 and a temperature of 40 DEG C for one hour to hydrolyze the amygdalin, and then extracting essential oil from the water solution by a water steam distillation method; wherein the distillation lasts for one hour. The invention further discloses an application of the bitter apricot kernel essential oil as a plant pathogenic fungus inhibitor. The extraction technology is simple, and the essential oil yield is high. The bitter apricot kernel has the advantages of low residue, safety, and easy degradation, and thus is a harmless plant-origin bacteriostatic agent.

The invention relates to anticorrosion system of infant wet tissue immersion liquid and a preparation method thereof. The anticorrosion system is prepared by mixing 0.5 to 1 part of paeonol, 15 to 20 parts of propanediol, 0.4 to 1 part of eucalyptus oil, 0.8 to 1.5 parts of eugenol, 0.01 to 0.02 part of tea tree oil, 10 to 15 parts of hydrogenated castor oil (PEG-40), 1 to 2.5 parts of sodium hexametahposphate, 0.01 to 0.05 part of Epsilon-polylysine, 0.02 to 0.05 part of natamycin and 60 to 72 parts of deionized water. Chemical bactericides, chemical fungistats and chemical bacterial inhibitors are not used; the safety is high; and sterilization, fungus inhibition and bacterium inhibition properties are good.

The present invention relates to a fungi inhibitor for harvested fresh fruits, wherein the fungi inhibitor comprises cinnamomum cassia, coptis chinensis, lithospermum erythrorhizon, portulaca oleracea, zanthoxylum bungeanum, asarum sieboldii miq, cinnamomum camphora leaf, sophora flavescens ait and garlic. According to the present invention, various components are washed, air-drying is performed, the dried components are added to clear water, boiling is performed, the water is evaporated to prepare an extract, the extract is prepared into the freeze-dried powder finished product by using a dryer, the freeze-dried powder is dissolved in water during the use, the dissolved solution is sprayed onto harvested fresh fruits, the continuous spraying is performed for 2 days, the infections of common Alternaria alternata, monilinia fructicola, Penicillium and a variety of plant diseases can be effectively inhibited, no residue exists, and the health of the eater can be ensured.

The invention relates to bread yeast strains that are effective in dough with a high sugar concentration, optionally in the presence of fungus inhibitors, to fresh or dry bread yeast obtained from said strains, and to those thereof in bread-making.

The invention discloses a construction method and application of recombinant Streptomyces lydicus for inhibiting plant pathogenic fungi. The method for constructing recombinant Streptomyces lydicus comprises the following step: transforming coding gene of a protein into Streptomyces lydicus as a host bacterium to obtain the recombinant Streptomyces lydicus. The protein is a) or b): a) protein of which the amino acid sequence is SEQ ID NO.1 in the sequence table; and b) protein with same functions subjected to substitution and / or deletion and / or addition of one or more amino acid residues on the amino acid sequence disclosed as SEQ ID NO.1 in the sequence table. The experiment proves that the Streptomyces lydicus AB01CGMCC No.10707 and RFRP can be used for inhibiting plant pathogenic fungi and preparing inhibitors for plant pathogenic fungi.

The invention provides thiophene chalcone semicarbazone Schiff base compounds, and a preparation method and applications thereof. Structure general formula of the thiophene chalcone semicarbazone Schiff base compounds is represented by a formula I in the invention, wherein R is used for representing single substitution or double substitution, and is used for representing fluorine atoms, chlorine atoms, bromine atoms, iodine atoms, methyl, methoxyl, or phenyl. The thiophene chalcone semicarbazone Schiff base compounds are simple and novel in structure, are convenient to be synthesized, and possess excellent control effects on plant pathogenic fungi. The thiophene chalcone semicarbazone Schiff base compounds are taken as plant pathogenic fungi inhibitors for the first time.

The invention relates to a substituted triaminotriazine compound and its preparation method and use in pharmacy. The substituted triaminotriazine compound has a general structural formula shown in the following description, and in the formula, R1 represents substituted phenyl ring and R2 represents substituted aromatic ring, naphthalene ring or heterocyclic aromatic. Through structure-based virtual screening and further structure reconstruction, the novel substituted triaminotriazine compound is synthesized. The novel substituted triaminotriazine compound is a fungus Sap2 inhibitor with a novel structure, has good enzyme inhibition activity and nematode in-vivo antifungal activity, provides a novel approach for deep research and development of novel-structure antifungal drugs and can be used for preparation of antifungal drugs and drugs for combination with the existing antibacterial drugs.

The invention discloses an application of N15 polypeptide in preparing a fungal inhibitor. The N15 polypeptide, as oligopeptide having 15 amino acids, has a plurality of biological functions, including regulating the capacity of an NF-kB transcription factor in binding a target gene, affecting transcription and expression of NF-kB target gene product protein, blocking PCNA to bind to DNA polymerase so as to prevent cell DNA synthesis and inhibit cell proliferation, inhibiting epithelial cell proliferation, and regulating epidermis hyperplasia and differentiation so as to normalize a skin keratinizing process and the like; according to the invention, the new biological functions of the 15 polypeptide are described, and the 15 polypeptide is relatively good in practicability and industrialization prospect.

The invention provides an application of ethyl maltol as a fungus inhibitor. According to the invention, ethyl maltol can serve as a fungus bacteriostatic agent to be applied to preparation of plant pesticides and plant seed coating agents, can also serve as the fungus bacteriostatic agent to be added into traditional Chinese medicine liquid preparations or semi-fluid preparations so as to effectively inhibit growth and reproduction of fungi including mould, can serve as a safe plant pesticide to reduce plant fungi diseases, inhibit mildewing and deterioration of seeds, reduce the mildewing and deterioration probability of the seeds or avoid the mildewing and deterioration of the seeds, and improve the seed germination rate, and can provide the inherent aroma enhancement function while integrating aroma enhancement, mildew prevention and corrosion prevention, enhance the stability of traditional Chinese medicine liquid preparations and semi-fluid preparations, replace or reduce the use of other toxic preservatives, reduce the use variety of additives, and reduce the potential safety risk of the additives, especially the preservatives.

The invention discloses a method for high-yield production of extracellular monascus red pigment by monascus purpureus fermentation, which is characterized in that a fungus inhibitor is specifically added in a monascus purpureus liquid fermentation process, so that the biosynthesis capability of monascus purpureus liquid fermentation monascus red pigment is greatly improved, and the monascus purpureus is promoted to secrete a large amount of extracellular monascus red pigment. The method is simple, extra labor and equipment are not added, the extracellular water-soluble monascus red pigment can be directly produced at high yield, the production cost of the monascus red pigment is reduced, and the method has great economic benefits and is suitable for industrial large-scale production.

The invention relates to a cutting fluid for metal working and a preparation method thereof, particularly a high-biological-stability semisynthetic metal cutting fluid. The cutting fluid is prepared from the following raw materials in percentage by weight: 1-10% of monoethanolamine, 2-10% of boric acid, 4-10% of dodecanedioic acid, 1-10% of base oil, 4-10% of oleic acid, 2-10% of organic acid ester, 0.2-2% of bacterial inhibitor, 1-5% of rust inhibitor, 5-10% of nonionic surfactant, 0.2-3% of fungus inhibitor, 0.01-0.5% of defoamer and the balance of water. The preparation method comprises the following steps: proportioning the material components according to the percentage by weight, adding the pure water, monoethanolamine, dodecanedioic acid and boric acid into a reaction kettle, continuously stirring for 30 minutes, adding the base oil, oleic acid, organic acid ester, bacterial inhibitor, rust inhibitor, nonionic surfactant and fungus inhibitor, continuously stirring for 30 minutes, finally adding the defoamer, and stirring until the fluid is uniform and transparent. Compared with the prior art, the cutting fluid provided by the invention has the advantages of favorable biological stability, excellent anti-rust property and excellent lubricating property.

The invention provides a biphenylmethanol compound. A general structural formula of the biphenylmethanol compound is shown in the specification, wherein in the general formula (I), n is 0.1; X is an oxygen atom or a sulfur atom; and R is a hydrogen atom, a chlorine atom, a bromine atom, methyl or methoxy. The biphenylmethanol compound provided by the invention has a simple and novel structure, is easy to synthesize, is low in cost, has better control effects on plant pathogenic fungi and is not reported in currently known plant pathogenic fungus inhibitors.

The invention provides a thiophene allyl alcohol compound. A general structural formula of the thiophene allyl alcohol compound is shown in the specification, wherein in the general formula (I), R1 is a hydrogen atom, a chlorine atom, a bromine atom, methyl or methoxy; and R2 is a fluorine atom, a chlorine atom, a bromine atom, an iodine atom, methyl, methoxy or nitro. The thiophene allyl alcohol compound provided by the invention has a simple and novel structure, is easy to synthesize, is low in cost, has better control effects on plant pathogenic fungi and is not reported in currently known plant pathogenic fungus inhibitors.

The invention discloses a taming technique of tissue cultivating sprout water-dielectric, which comprises the following steps: loading tissue cultivating sprout container in the taming chamber; adding fungal inhibiting agent and bacterium inhibiting agent; controlling light, temperature, air moisture to cultivate; placing tissue cultivating sprout in the transparent container with sponge or rock wool; adding taming base; controlling temperature and air moisture.

The invention relates to the technical field of municipal water supply and drainage, and discloses a municipal water supply and drainage culvert cleaning device which comprises a bottom plate, universal brake wheels are fixedly connected to the four corners of the bottom of the bottom plate, a supporting column is fixedly connected to the right side of the top end of the bottom plate, and a first mounting groove is formed in the right side of the interior of the supporting column; the culvert cleaning device for municipal water supply and drainage comprises a first mounting groove, second rotating rods are rotationally connected to the front portion and the rear portion of the interior of the first mounting groove correspondingly, straight gears are fixedly connected to the positions, located in the first mounting groove, of the outer surfaces of the second rotating rods, and toothed bars are connected to the opposite sides of the two straight gears in a meshed mode correspondingly. Therefore, the culvert cleaning device for municipal water supply and drainage is convenient to use and high in practicability, secondary reproduction of fungi can be inhibited to a certain extent by spraying a fungus inhibitor after cleaning, and the cleaning effect of the culvert cleaning device for municipal water supply and drainage is good.

The present invention relates to a substituted pyrazolone compound, a method for preparing the same, and application thereof in drug production, and belongs to the field of pharmaceutical technologies. The substituted pyrazolone compound is a newly discovered inihbitor of fungi Sap 2, and has certain antifungal activity. The prevent invention provides a substituted pyrazolone compound. The structure of the compound is as shown by the structural formula in the specification. The substituted pyrazolone compound provided by the prevent invention has better anti-cholinesterase activity of Sap 2. Compounds of the class can be used to prepare medicines used to treat fungal infections, which provides a new path to further research and development of new antifungal medicines.