The invention discloses a miniature liquid metal switch with a flexible structure. The miniature liquid metal switch comprises a base body, an upper liquid storage tank, a lower liquid storage tank, liquid metal, a liquid metal flow channel, an air flow channel, a top surface sealing thin film, a bottom surface sealing thin film, a side surface sealing thin film and an external electrode. The invention further provides a control method of the miniature liquid metal switch with the flexible structure. A high-elasticity matrix can be extruded through an external mechanical stress to enable the liquid metal to move for communicating with a circuit; and rapid circuit breaking can be realized through automatic springback of a high-elasticity matrix material and surface tension contraction of the liquid metal. The liquid metal is used as a conducting medium, and no contact resistor exists, so that electric repulsive force under a normal rated, short-circuit or lightning impulse current can be avoided, and meanwhile, the service life problem of an existing solid-state metal contact switch due to bouncing, fusion welding, ablation and the like is also favorably solved. The miniature liquidmetal switch is simple in structure, small in size and good in on-off performance, and can be applied to power on-off occasions of circuits.