The invention relates to a flow-guiding and energy-gathered type sea wave, tide, ocean current and wind power four-in-one power generation system. A base is arranged below the sea wave level and provided with a plurality of arc flow guiding plates which are evenly distributed along the circumference. The lower ends of supporting rods are connected with the arc flow guiding plates, and the upper ends of the supporting rods are connected with a platform. An accelerating machine is arranged on the platform, the upper end of a transmission pipe is in transmission with the accelerating machine, and the lower end of the transmission pipe penetrates through the platform and then is connected with a bearing; the bearing is arranged on the base. A plurality of fan blades and impellers are evenly distributed on the transmission pipe, and the impellers are located below the fan blades. The vertical end of one side of each arc flow guiding plate is close to the impellers, and the vertical end of the other side of each arc flow guiding plate is close to the outer edge of the base. A generator is arranged at the upper end of the accelerating machine and is in transmission with the accelerating machine. One end of a cable is connected with the generator, and the other end of the cable sequentially penetrates through the transmission pipe and the bearing and then is connected with a cable connector in the base. The power generation system has the beneficial effects that sea waves, tides, ocean currents and wind power act together to achieve high-power electricity generation, and sea water or wind power also can be used for independently generating power.