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191results about How to "Altered property" patented technology
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Tamper-protected hardware and method for using same
ActiveUS20140108786A1Execution of malicious code is preventedPreventing executionKey distribution for secure communicationMultiple keys/algorithms usageTamper proof hardwareComputer module
One of the various aspects of the invention is related to suggesting various techniques for improving the tamper-resistibility of hardware. The tamper-resistant hardware may be advantageously used in a transaction system that provides the off-line transaction protocol. Amongst these techniques for improving the tamper-resistibility are trusted bootstrapping by means of secure software entity modules, a new use of hardware providing a Physical Unclonable Function, and the use of a configuration fingerprint of a FPGA used within the tamper-resistant hardware.
Owner:EMSYCON
Enzymes for starch processing
InactiveUS20060148054A1Good curative effectActivity be alteredFungiSugar derivativesCarbohydrate-binding proteinAlpha-amylase
The present invention relates to polypeptides comprising a carbohydrate-binding module amino acid sequence and,an alpha-amylase amino acid sequence as well as to the application of such polypeptides.
Owner:NOVOZYMES AS +1
Method for in vitro molecular evolution of protein function
InactiveUS6989250B2Altered propertyIncreased complexitySugar derivativesMicrobiological testing/measurementNucleotideIn vivo
The present invention relates to a method for in vitro creation of molecular libraries evolution of protein function. Particularly, it relates to variability and modification of protein function by shuffling polynucleotide sequence segments. A protein of desired characteristics can be obtained by incorporating variant peptide regions (variant motifs) into defined peptide regions (scaffold sequence). The variant motifs can be obtained from parent DNA which has been subjected to mutagenesis to create a plurality of differently mutated derivatives thereof or they can be obtained from in vivo sequences. These variant motifs can then be incorporated into a scaffold sequence and the resulting coded protein screened for desired characteristics. This method is ideally used for obtaining antibodies with desired characteristics by isolating individual CDR DNA sequences and incorporating them into a scaffold which may, for example, be from a totally different antibody.
Owner:BIOINVENT INT AB
Durable medium-density fibre cement composite
ActiveUS20060288909A1Simple materialIncreased durabilitySolid waste managementCeramic shaping apparatusHigh densityCement composites
A cementitious product and method of modifying the properties of a low or medium density FRC product by providing a predetermined pore size distribution. The pore size distribution is obtained such that in critical zones of the distribution, the pore volume is substantially equivalent to or less than the pore volume in a respective critical zone of a conventional high density FRC product. The resultant material provides improved properties over conventional medium density FRC products, in particular improved freeze / thaw durability and / or improved workability.
Owner:JAMES HARDIE TECH LTD
Modified human interferon-beta polypeptides
InactiveUS7632492B2Altered propertyGood curative effectPeptide/protein ingredientsAntibody mimetics/scaffoldsChemical MoietyBiochemistry
The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
Owner:ALLOZYNE
n-Type thiophene semiconductors
InactiveUS6991749B2High yieldHigh purityConductive materialSolid-state devicesThin membraneOrganic semiconductor
The new fluorocarbon-functionalized and / or heterocycle-modified polythiophenes, in particular, α,ω-diperfluorohexylsexithiophene DFH-6T can be straightforwardly prepared in high yield and purity. Introduction of such modifications to a thiophene core affords enhanced thermal stability and volatility, and increased electron affinity versus the unmodified compositions of the prior art. Evaporated films behave as n-type semiconductors, and can be used to fabricate thin film transistors with FET mobilities ˜0.01 cm2 Vs—some of the highest reported to date for n-type organic semiconductors.
Owner:NORTHWESTERN UNIV
Nano Anticancer Micelles of Vinca Alkaloids Entrapped in Polyethylene Glycolylated Phospholipids
ActiveUS20090053293A1Good stabilityImprove drug distributionBiocidePharmaceutical non-active ingredientsVinorelbineAdjuvant
The present invention provides a nano-micellar preparation containing vinca alkaloids antitumor agent for intravenous injection, which cincludes a therapeutically effective amount of vinca alkaloids antitumor agent (vinblastine, vincristine, vindesine and vinorelbine), a phosphatide derivatized with polyethylene glycol, together with pharmaceutically acceptable adjuvants. The preparation is prepared by encapsulating the medicament with a nano-micelle to obtain the nano-micellar preparation containing vinca alkaloids antitumor agent for injection. The vinca alkaloids antitumor agent and the phosphatide derivatized with polyethylene glycol form a nano-micelle with a highly uniform particle size. In the micelle, the hydrophobic core of encapsulated medicament is surrounded by polyethylene glycol molecules to form a hydrophilic protective layer, so that the medicament is prevented from contacting with the enzymes and other protein molecules in blood and being recognized and phagocytozed by reticuloendothelial system in body, and the circulation time in vivo of the micelle is prolonged.
Owner:BEIJING DIACRID MEDICAL TECH
Tamper-protected hardware and method for using same
ActiveUS9071446B2Improve robustnessSuitable for useKey distribution for secure communicationMultiple keys/algorithms usageComputer hardwareTamper proof hardware
Owner:EMSYCON
Abrasive particles and methods of making and using the same
InactiveUS20030110706A1Facilitates formation and homogeneityOxide formationPigmenting treatmentOther chemical processesOxideMetal
Abrasive particles comprising ceramic (including glasses, crystalline ceramics, and glass-ceramics) comprising (on a theoretical oxide basis) Al2O3 and at least one other metal oxide (e.g., REO and; REO and at least one of ZrO2 or HfO2) and methods of making the same. The abrasive particles can be incorporated into a variety of abrasive articles, including bonded abrasives, coated abrasives, nonwoven abrasives, and abrasive brushes.
Owner:3M INNOVATIVE PROPERTIES CO
Method for selectively elevating and separating tissue layers and surgical instrument for performing the method
ActiveUS20090157114A1Expand selectionEasy to separateSurgical needlesDilatorsSurgical departmentSurgical device
Owner:ERBE ELEKTROMEDIZIN GMBH
Multiple-source arrays with optical transmission enhanced by resonant cavities
InactiveUS6847029B2Altered propertySpread the wordBeam/ray focussing/reflecting arrangementsMaterial analysis by optical meansResonant cavityOptical cavity
A multiple source array for illuminating an object including: a reflective mask having an array of spatially separated apertures; at least one optic positioned relative to the mask to form an optical cavity with the mask; and a source providing electromagnetic radiation to the optical cavity to resonantly excite a mode supported by the optical cavity, wherein during operation a portion of the electromagnetic radiation built-up in the cavity leaks through the mask apertures towards the object.
Owner:ZETETIC INST
Method and composition for the triggered release of polymer-degrading agents for oil field use
InactiveUS20050130845A1Avoid damageMaintain activityFluid removalFlushingChemical physicsPolymer degradation
Disclosed are methods and related compositions for altering the physical and chemical properties of a substrate used in hydrocarbon exploitation, such as in downhole drilling operations. In a preferred embodiment a method involves formulating a fluid, tailored to the specific drilling conditions, that contains one or more inactivated enzymes. Preferably the enzyme is inactivated by encapsulation in a pH responsive material. After the fluid has been introduced into the well bore, one or more triggering signals, such as a change in pH, is applied to the fluid that will activate or reactivate the inactivated enzyme, preferably by causing it to be released by the encapsulation material. The reactivated enzyme is capable of selectively acting upon a substrate located downhole to bring about the desired change in the chemical or physical properties of the substrate.
Owner:FREEMAN MICHAEL A +5
Method and apparatus for heat or electromagnetic control of gene expression
InactiveUS20070190028A1Increase expressionAltered propertyBiocideNervous disorderRegulator geneForms of energy
A gene regulatory system controls biomarker, gene therapy or endogenous gene expression by emitting one or more forms of energy that regulate gene expression. The system may include a sensor to sense a signal indicative of a need for therapy. The regulation of gene expression is controlled based on the sensed signal and / or a user command. In one embodiment, the system delivers one or more electrical therapies in conjunction with controlling gene therapy or endogenous gene expression.
Owner:CARDIAC PACEMAKERS INC
Process for the preparation of a pigment comprising a core material and at least one dielectric layer
InactiveUS20050013934A1Good absorbance of microwave energyImprove adhesionLiquid surface applicatorsPigment preparation by wet methodsAqueous solutionDielectric layer
The present invention relates to a process for the preparation of a pigment comprising a core material and at least one dielectric layer using microwave deposition of a metal oxide from an aqueous solution of fluorine scavenger onto a core material.
Owner:CIBA SPECIALTY CHEM CORP
Starch compositions and methods for use in papermaking
InactiveUS6451170B1Drainage and retention property is alteredImprove performanceNatural cellulose pulp/paperSpecial paperPapermakingChemistry
Owner:CARGILL INC
Cyclic dinucleotides for cytokine induction
ActiveUS20160362441A1Improve the immunityDelay EliminationAntibacterial agentsOrganic active ingredientsPurineIn vivo
A cyclic dinucleotide compound of Formula (I):wherein X1 is H or F; X2 is H or F; at least one among X1 and X2 is a fluorine atom; Z is OH, OR1, SH or SR1, wherein: R1 is Na or NH4, or R1 is an enzyme-labile group which provides OH or SH in vivo such as pivaloyloxymethyl; B1 and B2 are bases chosen from Adenine, Hypoxanthine or Guanine, and B1 is a different base than B2 and a pharmaceutically acceptable salt thereof. Pharmaceutical compositions including the cyclic dinucleotide, as well as their use in the treatment of a bacterial infection, a viral infection or a cancer are also described.
Owner:KAYLA THERAPEUTICS
Viricidal and microbicidal compositions and uses thereof
InactiveUS20120121679A1Reduced viabilityEfficient reductionAntibacterial agentsBiocideLevulinic acidActive agent
The present disclosure encompasses compositions comprising a surfactant, and an acid such as, but not limited to, levulinic acid, that together have a synergistic effect in reducing the viability of a virus population compared to the efficacy of the individual compounds. This synergy allows the formulation of compositions where the active agents (including an acid and a surfactant) are present at concentrations effective to inactivate viruses on surfaces, including human skin. The viricidal compositions disclosed herein are efficacious without damaging the surface to which they may be applied, or even altering the organoleptic properties of a treated food substance. The viricidal compositions and wipes containing such compositions are suitable for sanitizing any surface suspected of having a viral load thereon, or where it is desirable to ensure that a viral load is as low as possible.
Owner:UNIV OF GEORGIA RES FOUND INC
Variable Resistance Exercise and Rehabilitation Hand Device
InactiveUS20090017993A1Strong and highly tunable torque and force capabilityAltered propertyMuscle exercising devicesEngineeringSnubber
An exercising and rehabilitation hand device is disclosed. The hand device according to the invention is portable and controllable by smart fluid-based brakes / dampers to provide a compact, lightweight mechanism whose resistance to motion can be changed on-the-fly, through computerize control, to vary the exercises that can be performed and tune the workout or rehabilitation session to the responses of the user.
Owner:NORTHEASTERN UNIV
Subtilases
ActiveUS7294499B2High activityIncrease specific activityBacteriaDetergent compounding agentsImmunologySubtilase
Owner:NOVOZYMES AS
Amino acid substituted molecules
UndeterminedUS20080096819A1Altered propertyGood curative effectFactor VIIPeptide/protein ingredientsChemical MoietyAmino acid substitution
The invention provides compositions and methods of identifying, modifying and producing modified target molecules, including therapeutic molecules by modification with non-natural amino acids. Certain aspects of the invention include methods of adding a chemical moiety to a target molecule, and the compositions resulting therefrom. Certain aspects of the invention also relate to kits for identifying, modifying and producing modified target molecules described herein.
Owner:ALLOZYNE
Cosmetic compositions
InactiveUS20050244441A1Improve stabilityReduce fragranceCosmetic preparationsToilet preparationsEmulsionMedicine
Owner:UNILEVER HOME & PERSONAL CARE USA DIV OF CONOPCO IN C
Cyclic dinucleotides for cytokine induction
ActiveUS10011630B2High activityImprove bioavailabilityAntibacterial agentsOrganic active ingredientsPurineIn vivo
A cyclic dinucleotide compound of Formula (I):wherein X1 is H or F; X2 is H or F; at least one among X1 and X2 is a fluorine atom; Z is OH, OR1, SH or SR1, wherein: R1 is Na or NH4, or R1 is an enzyme-labile group which provides OH or SH in vivo such as pivaloyloxymethyl; B1 and B2 are bases chosen from Adenine, Hypoxanthine or Guanine, and B1 is a different base than B2 and a pharmaceutically acceptable salt thereof. Pharmaceutical compositions including the cyclic dinucleotide, as well as their use in the treatment of a bacterial infection, a viral infection or a cancer are also described.
Owner:KAYLA THERAPEUTICS
Preparation of carbon nanotubes
InactiveUS20030161782A1Small particle sizeUniform supplyMaterial nanotechnologyNanostructure manufactureGas phaseCarbon nanotube
The present invention is to provide a process for the preparation of carbon nanotubes or nanofibers, which comprises introducing in a gaseous phase a colloidal solution of metal nanoparticles optionally containing a surfactant together with an optional carbon source into a heated reactor, and carbon nanotubes or nanofibers thus prepared. According to the present invention, the shape and structure of carbon nanotubes or nanofibers can be easily controlled, the carbon nanotubes or nanofibers can be continuously produced in large scales, the apparatus and the process for the preparation of nanotubes or nanofibers are simplified, and carbon nanotubes or nanofibers having various shapes, structures and properties can be easily and cheaply prepared. Further, the process of the present invention is highly reproducible and favorable in industry.
Owner:KH CHEM CO LTD
Nutritional compositions
InactiveUS20060073186A1Suppress in productionSuppression of inflammatory cytokine productionOrganic active ingredientsSugar food ingredientsInterleukin 6Hydrolysate
The present inventors discovered that the onset of galactosamine hepatopathy is suppressed by nutritional compositions comprising as essential ingredients: whey protein hydrolysates; lecithin and oils and fats high in oleic acid, which are able to improve the lipid metabolism; and palatinose having an insulin-sparing effect. Furthermore, the whey protein hydrolysate included in the nutritional compositions was found to suppress endotoxin-induced TNF-a and interleukin 6 (IL-6) production in macrophages.
Owner:MEIJI CO LTD
Electrochromic device
InactiveUS20020126365A1High ionic conductivityLess ionic conductivityNanoinformaticsDigital storageElectricityBiomedical engineering
A supported or self-supporting electrochromic device is provided, comprising: at least one electrochromic element comprising (i) at least one material that is electrically conducting in at least one oxidation state and (ii) at least one electrochromic material, wherein said materials (i) and (ii) can be the same or different, at least one layer of a solidified electrolyte which is in direct electrical contact with said electrochromic element, and at least two electrodes adapted to be electrically connected to a voltage supply so as to create a difference in potential therebetween; each of said electrodes being in direct electrical contact with at least one of said electrolyte layer(s) and not in direct electrical contact with said electrochromic element. Also provided are displays incorporating such a device, as well as processes for the production of such a device. A method for addressing an electrochemically active element is also provided.
Owner:ACREO
Semiconductor laser element
InactiveUS7103082B2Easy to getInhibition releaseOptical wave guidanceLaser detailsSemiconductor packageActive layer
To provide a semiconductor laser device which has no ripple and can afford better FFP having a pattern near a Gaussian distribution upon operation at the high output, the semiconductor laser comprising a laminate structure in which a first conductive type semiconductor layer, an active layer and a second conductive type semiconductor layer different from the first conductive type are laminated in this order, the laminate structure having a waveguide region to guide a light and resonator planes for laser oscillation on both ends, characterized in that the laminate structure has a non-resonator plane on one end side and the non-resonator plane is covered with a shading layer.
Owner:NICHIA CORP
Method of altering the refractive properties of an eye
InactiveUS9814567B2Altering refractive propertyPain reliefLaser surgeryEye implantsPhotosensitizerCross linker
The present invention relates to a method of altering the refractive properties of the eye, the method including forming a pocket in a cornea of an eye of a patient so as to gain access to tissue bounding the pocket; after the pocket in the cornea has been formed, applying a photosensitizer inside the pocket so that the photosensitizer permeates at least a portion of the tissue bounding the pocket, the photosensitizer facilitating cross-linking of the tissue bounding the pocket; inserting a lens implant into the pocket so as to change the refractive properties of the eye; and irradiating the cornea so as to activate cross-linkers in the portion of the tissue bounding the pocket and thereby stiffen the cornea and prevent corneal ectasia of the cornea.
Owner:PEYMAN GHOLAM A
Inverted novolac resin-type insulation binder
A substantially infinitely water-dilutable resole (P:F) resin solution useful for preparing an aqueous binder composition and the related method of its use for making glass fiber products, especially fiberglass insulation.
Owner:GEORGIA PACIFIC CHEM LLC
Tamper-protected hardware and method for using same
ActiveUS20150161415A1Improve robustnessSuitable for useMultiple keys/algorithms usagePublic key for secure communicationComputer hardwareTamper resistance
One of the various aspects of the invention is related to suggesting various techniques for improving the tamper-resistibility of hardware. The tamper-resistant hardware may be advantageously used in a transaction system that provides the off-line transaction protocol. Amongst these techniques for improving the tamper-resistibility are trusted bootstrapping by means of secure software entity modules, a new use of hardware providing a Physical Unclonable Function, and the use of a configuration fingerprint of a FPGA used within the tamper-resistant hardware.
Owner:EMSYCON
Method of altering the refractive properties of an eye
InactiveUS20170007395A1Altering refractive propertyReduce postoperative painLaser surgeryEye implantsPhotosensCross linker
The present invention relates to a method of altering the refractive properties of the eye, the method including forming a pocket in a cornea of an eye of a patient so as to gain access to tissue bounding the pocket; after the pocket in the cornea has been formed, applying a photosensitizer inside the pocket so that the photo sensitizer permeates at least a portion of the tissue bounding the pocket, the photosensitizer facilitating cross-linking of the tissue bounding the pocket; inserting a lens implant into the pocket so as to change the refractive properties of the eye; and irradiating the cornea so as to activate cross-linkers in the portion of the tissue bounding the pocket and thereby stiffen the cornea and prevent corneal ectasia of the cornea.
Owner:PEYMAN GHOLAM A
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