The invention is suitable for the technical field of display, and provides an array substrate, a manufacturing method and a display panel, the array substrate comprises a first substrate, a common electrode wire, a color resistance layer and a flat layer, the color resistance layer comprises a first color resistance block and a second color resistance block which are adjacent, according to the array substrate, the color resistance grooves located on the common electrode lines are formed between the first color resistance blocks and the second color resistance blocks, the first color resistance blocks and the second color resistance blocks are prevented from being overlapped above the common electrode lines, the width of the common electrode lines is small, and it can be guaranteed that the array substrate has the high aperture ratio; in addition, the array substrate further comprises a flat layer, and the color resistance grooves are filled with the filling parts of the flat layer. The color resistance grooves can be reduced or even eliminated, the adjacent first color resistance blocks and second color resistance blocks are flat, when a pixel electrode layer is formed on the color resistance layer in a deposition and etching mode, etching residues of transparent conductive materials in the color resistance grooves can be avoided, the etching yield is improved, and the display quality is guaranteed.