The present invention provides a water resistance metal binder and a preparation method thereof, wherein the binder comprises methyltriethoxysilane, ethyl silicate, an alpha-cyanoacrylate glue, a bisphenol F epoxy resin, an E-39 epoxy resin, p-hydroxybenzenesulfonic acid, hydroxyethyl cellulose, sodium alginate, cobalt boroacylate, nanometer titanium dioxide, barium sulfate, calcium lactate, calcium citrate, tetrapod-like zinc oxide crystal whisker, ethanol, dilute hydrochloric acid and water. The preparation method comprises: stirring methyltriethoxysilane, ethyl silicate and ethanol at a temperature 75-85 DEG C, adding a mixing solution of dilute hydrochloric acid and water, adding other components excluding p-hydroxybenzenesulfonic acid after the solution is clarified, heating to a temperature of 45-55 DEG C, carrying out thermal insulation for 15-30 min, adding p-hydroxybenzenesulfonic acid, heating to a temperature of 120-140 DEG C, and maintaining for 2-3 h. According to the present invention, the metal binder has characteristics of high binding strength and water resistance, and does affect the connection after the instrument contacts water even is soaked in water; and the preparation method has characteristics of simple steps, easy control, easy industrial production, and low production cost.