Product
Patsnap Eureka
For R&D, Patsnap Eureka makes reading and utilizing patents & technical documents easy.
Patsnap Eureka AIR
Designed for self-driven R&D workflows. Generate viable solutions, solve complex R&D challenges, empower your innovation with AI.
Patsnap Eureka Materials
Designed for material experts only. Revolutionize your material R&D, from search, analyze, to developing new materials.
Feature
TechResearch
Generate reliable direction feasibility study reports for your R&D in just a few steps.
TechSeek
Discover and master advanced knowledge NOW. Basics, ideas, possibilities, all at once.
TechMind
As an expert in R&D Theories, TechMind can generates customized viable solutions instantly.
TechRisk
Analyze your overall solution with one click, know your potential R&D risks in advance.
TechMonitor
Get weekly tech updates, stay abreast of the latest tech innovations and key insights.
Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
31results about How to "Increase solubility" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
Chemical linkers and conjugates thereof
ActiveUS20060024317A1Increase solubilityDecrease aggregationMaterial nanotechnologyHybrid immunoglobulinsDrugToxin
The present disclosure provides drug-ligand conjugates that are potent cytotoxins, wherein the drug is linked to the ligand through either a peptidyl, hydrazine, or disulfide linker. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.
Owner:MEDAREX LLC
Controlled-release emulsion compositions
InactiveUS20070104778A1Increase solubilityImprove solubilityBiocidePharmaceutical non-active ingredientsActive agentEmulsion
The present invention is directed to controlled-release composition containing a solubilized material comprising an active agent and at least one oil-based surfactant capable of solubilizing the active agent, the solubilized material dispersed in a controlled-release particulate matrix.
Owner:PENWEST PHARMA CO
Methods and systems for coating an oral surface
ActiveUS20070202342A1Increase solubilityIncrease anti-microbial activityMaterial nanotechnologyBiocideAmmonium compoundsPersonal care
An antimicrobial coating system and method are described. In some embodiments, a system may include a composition. The composition may include one or more bridged polycyclic compounds. At least one of the bridged polycyclic compounds may include at least two cyclic groups, and at least two of the cyclic groups may include quaternary ammonium moieties. In some embodiments, a method may include applying an antimicrobial coating to an oral surface, a surface of a construction substrate, a surface of a marine substrate, a surface of a medical device, or a surface of a personal care device. The protective coating may be antimicrobial. A protective coating may include antimicrobial bridged polycyclic compounds. Bridged polycyclic compounds may include quaternary ammonium compounds. Bridged polycyclic compounds based coating systems may impart self-cleaning properties to a surface (e.g., a tooth surface).
Owner:ALLACCEM
Multifunctional Metal Nanoparticles Having A Polydopamine-Based Surface and Methods of Making and Using the Same
InactiveUS20120237605A1Increase solubilityAntibacterial agentsPowder deliveryBrown iron oxideImage contrast
The present invention provides nanoparticles including a metallic core having a length along each axis of from 1 to 100 nanometers and a coating disposed on at least part of the surface of the metallic core, wherein the coating comprises polydopamine, along with methods for making and using such nanoparticles. The metallic core may be gold, silver or iron oxide and the polydopamine coating may have other substances bound to it, such as silver, targeting ligands or antibodies, or other therapeutic or imaging contrast agents. The disclosed nanoparticles can be targeted to cells for treating cancer or bacterial infections, and for use in diagnostic imaging.
Owner:NORTHWESTERN UNIV
Interferon variants with improved properties
InactiveUS20050054053A1Increase solubilityIncrease specific activitySugar derivativesPeptide/protein ingredientsCancer researchInterferon
Owner:XENCOR
Conjugated proteins with prolonged in vivo efficacy
InactiveUS20110223151A1Increase solubilityReadily convertFactor VIIPeptide/protein ingredientsDrugHaemophilia
The invention relates to conjugated proteins, in particular but not exclusively, blood coagulation factors, to processes for preparing said conjugates, to pharmaceutical compositions comprising said conjugates and to the use of the conjugates in therapy, in particular but not exclusively, for the treatment of diseases alleviated by blood coagulation factors such as the prophylactic treatment of hemophilia.
Owner:NOVO NORDISK AS
Lithium ion electrolyte and lithium ion battery using same
InactiveCN109546219AImproved high temperature storage and high temperature cycling performanceIncrease solubilitySecondary cells servicing/maintenanceOrganic electrolytesSolventVinylene carbonate
A lithium ion electrolyte and a lithium ion battery using the same are provided. The lithium ion electrolyte includes a solvent, a lithium salt, and an additive. The lithium salt includes lithium hexafluorophosphate (LiPF6), high-content bistrifluoromethylsulfonimide (LiTFSI) and / or lithium bis(fluorosulfonyl)imide (LiFSI). The additive includes vinylene carbonate ester (VC), fluoroethylene carbonate (FEC), 1,3 propane sultone (PS), and ethylene carbonate (VEC). The electrolyte of the present invention can improve the cycling and high-temperature storage performance of a lithium battery by using the high-content bistrifluoromethylsulfonimide (LiTFSI) and / or lithium bis(fluorosulfonyl)imide (LiFSI) in combination with a negative electrode film-forming additive and / or a positive electrode protective additive. The lithium ion electrolyte is applicable to lithium ion batteries in a range of 4.2V and above.
Owner:ZHUHAI COSMX BATTERY CO LTD
Compositions and methods of using them
InactiveUS20030219494A1Increase viscosityIncrease solubilityBiocideNervous disorderDrugPainful diabetic neuropathy
The present invention is directed to compositions and methods for inducing, promoting or otherwise facilitating pain relief. More particularly, the present invention relates to the use of a compound which either directly or indirectly prevents, attenuates or reverses the development of reduced opioid sensitivity, together with a compound which activates the opioid receptor that is the subject of the reduced opioid sensitivity, in methods and compositions for the prevention or alleviation of pain, especially in neuropathic conditions and even more especially in peripheral neuropathic conditions such as painful diabetic neuropathy (PDN).
Owner:QUEENSLAND UNIV OF
Improved chemical mechanical polishing of nickel phoshorous alloys
InactiveUS20030171072A1Increase solubilityPrevent redepositionOther chemical processesAbrasion apparatusChemical-mechanical planarizationCompound (substance)
CMP formulations for use on nickel / phosphorus alloys comprising abrasive particles and an oxidant, a modifier for the action of the oxidant and first and second accelerants to sequester removed materials containing phosphonate and ammonium or amine groups respectively and optionally an organic carboxylic acid.
Owner:SAINT GOBAIN CERAMICS & PLASTICS INC
Gallium Formulation For The Treatment And Prevention of Infectious Diseases
ActiveUS20120128729A1Increase solubilityPrevent deliveryBiocideAntiparasitic agentsGramKlebsiella oxytoca
A method and composition for treatment of bacterial infections caused by gram negative or gram positive bacteria such as Staphylococcus aureus, Rhodococcus equi, Mycobacterium tuberculosis, Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a formulation containing gallium (III), in a pharmaceutically acceptable salt or complex thereof.
Owner:ARIDIS PHARMA INC
Planographic printing plate precursor and method of producing the same
InactiveUS20060216639A1Inhibit developmentIncrease solubilityPhotosensitive materialsPhotomechanical apparatusLaser lightSolubility
A planographic printing plate precursor of the present invention comprises: a support and a positive recording layer arranged on the support. the positive recording layer containing resin and an infrared absorber and being constituted of two or more sub-layers, wherein the solubility of the positive recording layer to an aqueous alkali solution is increased by exposure to infrared laser light, and for the positive recording sub-layer of the two or more positive recording sub-layers that is nearest to the support (the lower layer), the ratio of the dissolution speed to an aqueous alkali solution in the lateral direction to the dissolution speed in the depth direction is less than 1. Such a ratio of the dissolution speeds can be achieved by forming a dispersed phase in the lower layer and / or high-temperature drying when forming the lower layer. According to the invention, there is provided a positive planographic printing plate precursor for infrared laser for direct plate making, which is excellent in scratch resistance and in discrimination of formed images.
Owner:FUJIFILM CORP +1
Orally Bioavailable Lipid-Based Constructs
ActiveUS20100310599A1Improve bioavailabilityIncrease solubilityBiocideVitamin food ingredientsEndocrinologyLipid formation
The present invention is embodied by a composition capable inducing weight loss in a patient in need thereof.
Owner:SDG INC (US)
Sic single crystal and production method thereof
InactiveUS20120237428A1Effective crystal growth rateIncrease solubilityPolycrystalline material growthFrom melt solutionsSolventSeed crystal
A method is disclosed with provides stable growth of SiC single crystals, particularly 4H—SiC single crystals, with an effective crystal growth rate for a prolonged time even at a low temperature range of 2000° C. or lower. A raw material containing Si, Ti and Ni is charged into a crucible made of graphite and heat-melted to obtain a solvent. At the same time, C is dissolved out from the crucible into the solvent to obtain a melt. A SiC seed crystal substrate is then brought into contact with the melt such that SiC is supersaturated in the melt in the vicinity of the surface of the SiC seed crystal substrate, thereby allowing growth and production of an SiC single crystal on the SiC seed crystal substrate.
Owner:FUJI ELECTRIC CO LTD
Compositions and methods for the encapsulation and scalable delivery of agrochemicals
PendingUS20200113177A1Increase solubilityIncrease diffusionBiocideHydrolasesAgricultural scienceEngineering
The present disclosure is generally directed to an anucleated cell-based platforms for encapsulation and delivery of agricultural compounds. Disclosed herein are compositions for the stable and targeted delivery of agricultural compounds within achromosomal and / or anucleated cells. The present disclosure also provides methods of improving encapsulation and retention of agricultural compounds in achromosomal and / or anucleated cells.
Owner:AGROSPHERES INC
Solvent, extraction of impurities from concentrated metal sulphate solutions
InactiveUS20080003154A1Increase solubilityImprove solubilitySolvent extractionAmmonium sulfatesNickelZinc
The present invention relates generally to a two step solvent extraction circuit to remove impurity metals of zinc and cobalt selectively from a valuable metal of nickel. In order to selectively extract zinc there must be sufficient separation between zinc and cobalt in the cyanex 272 system. Similarly for cobalt and nickel, the separation factor must be of sufficient magnitude to obtain a pure nickel product. The process for the solvent extraction of impurity metals is operated at a temperature exceeding 60° C. being the maximum temperature at which solvent extraction circuits conventionally operate.
Owner:OCALLAGHAN JOHN +1
Electrochemically regenerated water deionization
ActiveUS20130199931A1Easily removeIncrease solubilitySludge treatmentVolume/mass flow measurementIonChemistry
An apparatus and method for abating scale formation during the purification and demineralization of water in an electrochemical deionization apparatus. In the apparatus and method, scale forming ions in a raw water feed are precipitated at a controlled location remote from the deionization chambers of the deionization apparatus. Concentrate water produced during the deionization process to produce demineralized product water is acidified and circulated through the deionization apparatus to prevent scale formation and build-up in the deionization apparatus.
Owner:TANGENT COMPANY
Wnt7a compositions and method of using the same
ActiveUS20150111822A1Increase solubilityIncrease ratingsPeptide/protein ingredientsGenetic material ingredientsMolecular biologyStem cell
There are provided compositions and methods for modulating stem cell division, in particular, division symmetry. It has been demonstrated that Wnt7a polypeptide fragments promoting symmetrical expansion of stem cells. The compositions and methods of the invention are useful, for example, in modulating stem cell division symmetry in vitro, ex vivo, and in vivo, in replenishing and expanding the stem cell pool, and in promoting the formation, maintenance, repair and regeneration of tissue.
Owner:OTTAWA HOSPITAL RES INST
Planographic printing plate precursor
InactiveUS20050202342A1Increase solubilityImprove solubilityDiazo compound compositionsLithographyPHENOL LIQUIDChemistry
A planographic printing plate precursor comprises: a support; and a recording layer disposed on the support, the recording layer comprising a lower layer and an upper layer disposed on the lower layer, wherein the lower layer contains a resin having in a main chain structure a phenol skeleton and a urea bond, the upper layer contains a water-insoluble alkali-soluble resin and an infrared absorber, and the solubility of the upper layer in an aqueous alkali solution is increased by exposure. The planographic printing plate precursor can be produced directly through scanning exposure based on digital signals. It is superior in reproducibility of highly fine images and also superior in printing durability and chemical resistance of small-area image areas such as halftone dots and thin lines.
Owner:FUJIFILM CORP +1
Method of detection of analyte active forms and determination of the ability of substances to bind into analyte active sites
ActiveUS20170219583A1Increase solubilityDecrease free energy activation barrierMicrobiological testing/measurementBiological material analysisAmount of substanceActive site
Owner:USTAV ORGANICKE CHEM A BIOCHEM ACAD VED CR
Method for the purification of protein complexes
ActiveUS20120135029A1Safe to useIncrease solubilitySsRNA viruses negative-senseSsRNA viruses positive-senseIon exchangeProtein protein
The present invention provides an improved method for the purification of a mixture of complexes comprising a stress protein complexed to a peptide or peptide fragment from a source mixture, typically a cell lysate. The method of the invention provides for protein complexes to be purified using ion exchange chromatography based methods, wherein a modified buffer solution is used which results in the purified stress protein complexes being more immunogenic than protein complexes obtained using conventional methodology. The purified complexes can be used to produce improved vaccine preparations which elicit enhanced immune responses in the subjects to whom the vaccine compositions are administered.
Owner:IMMUNOBIOLOGY LTD
Method for producing algae in thin
InactiveUS20130137171A1Increase solubilityFacilitate growthBioreactor/fermenter combinationsBiological substance pretreatmentsBiological growthPhotobioreactor
The present method transfers carbon dioxide in increased concentrations using perfluorodecalin for growth of algae in a photobioreactor. First, a perfluorodecalin solution is provided and mixed with a biological growth medium and a surfactant. The biological growth medium, perfluorodecalin solution, and surfactant mixture are then emulsified by circulation in a high-pressure emulsifier. The emulsified biological growth medium, perfluorodecalin solution, and surfactant mixture are then added to a photobioreactor containing algae capable of photosynthetically utilizing carbon dioxide. After adding carbon dioxide to the photobioreactor, the carbon dioxide dissolves in the perfluorodecalin solution at a higher concentration than in the growth medium. Conditions sufficient for the algae to perform photosynthesis using carbon dioxide from the perfluorodecalin solution are maintained thereby increasing the growth rate of the algae in increased concentration of carbon dioxide due to the increased solubility of carbon dioxide in the perfluorodecalin solution.
Owner:DRESSLER LAWRENCE V +1
Frozen confections
InactiveUS20090142464A1Reduce benefitIncrease solubilityFood ingredient as buffering agentFrozen sweetsFood science
A frozen confection is provided, having a pH of from 4.7 to 5.5 and comprising (by weight of the confection): 10 to 35% sweeteners; 0.6 to 3% of a buffer; at most 2% protein; and at most 2% fat. A process for making the frozen confection is also provided.
Owner:CONOPCO INC D B A UNILEVER
Polymer excipients for drug delivery applications
ActiveUS20210214496A1Increase solubilityImprove solubilityOrganic active ingredientsPowder deliveryDrug deliveryAmino acid
The present disclosure relates to the field of polymer chemistry and more particularly to multiblock copolymers comprising a poly(sarcosine) block and a D,L-mixed poly(amino acid) block and uses thereof.
Owner:TYNDALL FORMULATION SERVICES LLC
Novel form of rimsulfuron, a process for its preparation and use of the same
ActiveUS20160286814A1Increase solubilityDecrease viscosityBiocideOrganic chemistry methodsMedicinal chemistryGrowth plant
A crystal form of rimsulfuron is provided that exhibits improved solubility and decreased viscosity. Furthermore, a process for its preparation is provided. The novel crystal form is particularly suitable for use in herbicidal compositions and in the control of unwanted plant growth.
Owner:ROTAM AGROCHEM INT CO LTD
Process for preparing a solution of lignin in an aqueous medium
PendingUS20220033561A1Increase solubilityImprove solubilityAldehyde/ketone condensation polymer adhesivesLignin derivativesChemistryPhenol formaldehyde resin
Owner:STORA ENSO OYJ
Zn (II) based colorimetric sensor and process for the preparation thereof
InactiveUS20130130306A1Increase solubilityIncrease intensity of stainMicrobiological testing/measurementPreparing sample for investigationAdenosine triphosphateBiological body
A colorimetric chemosensor molecule having a aza-macrocycle Zn (II)-complex (L.Zn) (Scheme 1, Formula 1A) which can recognize selectively and efficiently ATP (Adenosine triphosphate), a biologically significant triphosphate in aqueous medium at pH 7.4 is described. Since ATP is the source of energy in living organisms, L.Zn (Scheme 1, Formula 1A) can also be used as a staining agent in the living cells through binding to ATP, generated in situ during the metabolic process.
Owner:COUNCIL OF SCI & IND RES
Personal Care Compositions Comprising Zinc : Usnic Acid Complexes and Methods of Use
ActiveUS20210401694A1Increase solubilitySoap detergents with organic compounding agentsCosmetic preparationsPersonal careAnti bacterial
Disclosed herein are personal care compositions comprising Zn:usnate complexes having a 1:2 zinc to usnate molar ratio. Methods of making and using the compositions are also provided. The personal care compositions may include a cleansing component and an antibacterial component, wherein the antibacterial component comprises Zn:usnate complexes having a 1:2 zinc to usnate molar ratio.
Owner:COLGATE PALMOLIVE CO
Kinetin/zeatin topical formulation
ActiveUS20140271826A1Increase solubilityImprove solubilityCosmetic preparationsBiocideSolubilityKinetin
The solubility of kinetin and / or of zeatin is increased when either or both are combined in a formulation that includes a polyoxyalkylene-n-glycerol dicarboxylate component and a fatty acid component. These two components provide a synergistic increase in the solubility of kinetin and / or zeatin that is greater than that which would be expected based on the solubility of kinetin and zeatin in the individual components.
Owner:BAUSCH HEALTH IRELAND LTD
Semiconductor material and method for enhancing solubility of a dopant therein
InactiveUS6872455B2Increase solubilityImprove solubilityPolycrystalline material growthAfter-treatment detailsP type dopingIndium
A method for enhancing the equilibrium solubility of boron ad indium in silicon. The method involves first-principles quantum mechanical calculations to determine the temperature dependence of the equilibrium solubility of two important p-type dopants in silicon, namely boron and indium, under various strain conditions. The equilibrium thermodynamic solubility of size-mismatched impurities, such as boron and indium in silicon, can be raised significantly if the silicon substrate is strained appropriately. For example, for boron, a 1% compressive strain raises the equilibrium solubility by 100% at 1100° C.; and for indium, a 1% tensile strain at 1100° C., corresponds to an enhancement of the solubility by 200%.
Owner:LAWRENCE LIVERMORE NAT SECURITY LLC
Who we serve
- R&D Engineer
- R&D Manager
- IP Professional
Why Patsnap Eureka
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com