30results about How to "Reasonable design ideas" patented technology

The invention discloses a polyolefin nanometer fiber film sensor for rapid bacterium detection and a preparation method thereof. According to the invention, polyolefin copolymer is adopted as a substrate material, and the chemically-modified polyolefin nanometer fiber film biosensor is prepared by surface chemical modification, and solid phase synthetic process of bioactive molecules. The nanometer fiber film biosensor prepared by the method of the invention overcomes, with respect to performance, the disadvantages of time consumption, manpower consumption, poor accuracy for bacterium culture and bacterial colony counting in traditional bacterium detection, realizes rapid detection of ATP released by bacteria by using the luminescence principle between triphosadenine, luciferase, and fluorescein, and realizes rapid response to biological harmful substances. With the solid phase synthesis, bioactive enzymes are well fixed on the surface of the nanometer fiber film, which realizes repeated and circular detection of bacteria. The nanometer fiber film sensor is widely applicable to fields of biotechnology, medical health, food and medicine detection, water treatment, and the like.

The invention discloses a blown film winding device in automatic correction. The blown film winding device in automatic correction comprises a rack which is of an arch-shaped structure, and inclined side plates are symmetrically installed on the two sides of the rack; a film entering roller is connected to one of the side plates through a bearing pedestal, and a film discharging roller is connected to the other side plate through a bearing pedestal; a screw is movably connected to the rack; the upper end of the screw is connected with the lower plane of a balance plate through a bearing; the left side of the balance plate is connected with a film leading roller through a bearing; and a correction roller is installed on the right side of the balance plate. The blown film winding device in automatic correction is compact in structure, reasonable in design thought, novel and unique; in the blown film winding process, it is guaranteed that a blown film is wound more orderly by means of correction, rib exposing is reduced, bag making before opening printing is facilitated, opening materials for use can be reduced, and meanwhile cost can be greatly reduced.

The present invention relates to the field of organic photovoltaic materials, in particular to a tripcene-based peryleneimide compound and its preparation method and application. The structural formula of the peryleneimide compound based on tripterene is shown as T-1, T-2 or T-3: wherein, R 1 Any group selected from the following: C 2‑60 Alkyl, substituted alkyl, alkoxy, substituted alkoxy, aryl, substituted aryl, alkylaryl, substituted alkylaryl, alkylhetero Aryl, substituted alkylheteroaryl, alkylheterocyclyl or substituted alkylheterocyclyl; R 1 same or different. The tripterene-based peryleneimide compound of the present invention obviously improves the photoelectric conversion efficiency, has reasonable and effective design ideas, simple molecular structure, and short synthesis steps, and is an organic solar cell material with important application prospects.

The invention discloses an optical fiber distributed multi-point online gas monitoring system and its host, including the host and monitoring probes distributed at each monitoring point. A laser is installed in the host, and the output end of the laser is connected to the input end of an input optical switch. The output end of the input optical switch is connected to each corresponding monitoring probe through the input optical fiber, and each monitoring probe is connected to the corresponding input end of the output optical switch provided in the host through the output optical fiber, and the output end of the output optical switch is connected to the infrared photodetector; The host is also provided with a control module for controlling the output optical switch and the input optical switch to strobe and set the corresponding optical path of the monitoring probe. The main engine of the present invention uses an optical switch to realize time-division multiplexing of laser light. Under the condition of the same power laser, the optical fiber sensor can be distributed farther; in addition, only a single infrared photoelectric sensor needs to be set after the output optical switch, which reduces the cost. .

The invention discloses a lipoic acid modified chondroitin sulfate-chlorin e6 amphoteric polymer. According to the polymer, chondroitin sulfate is used as a water-soluble framework material, chlorin e6 serves as a hydrophobic modifier to be connected into a chondroitin sulfate framework, lipoic acid is used as an interface cross-linking agent to conduct surface modification on a chondroitin sulfate-chlorin e6 polymer, and the polymer further has a hydrophobic core to be capable of entrapping an insoluble anti-tumor drug. The lipoic acid modified chondroitin sulfate-chlorin e6 amphoteric polymer prepared by the invention is used as a drug carrier to prepare reversible cross-linked nano-micelles, and thus rapid decrosslinking in tumor cells can be realized; and as an excellent nano-carrier,sonodynamic therapy (SDT) of the tumors is achieved, and the lipoic acid modified chondroitin sulfate-chlorin e6 amphoteric polymer has the effects of increasing the level of active oxygen in the cells, promoting tumor cell apoptosis and remarkably inhibiting tumor cell growth. Meanwhile, the hydrophobic core provides entrapment of the anti-tumor drug, combined application of chemotherapy and SDTof the tumors can be achieved, and the anti-tumor effect is expected to be improved.

The invention relates to a temperature controller insulation post assembling device. The temperature controller insulation post assembling device comprises an insulation post feeding mechanism, an insulation post assembling mechanism and a bottom plate, wherein the insulation post assembling mechanism comprises a pushing air cylinder, a displacement block, a righting air cylinder, a clamping block, a stop block and a stop air cylinder; the pushing air cylinder is fixed to the bottom plate; one side of the displacement block is fixedly connected with the output end of the pushing air cylinder,and the righting air cylinder is fixed to the other side of the displacement block; the output end of the righting air cylinder is fixedly connected with the clamping block; the stop air cylinder is fixed above the clamping block; the stop block is fixedly connected with the output end of the stop air cylinder; the front end of the clamping block is provided with a round hole structure used for clamping insulation post; and the round hole structure is driven by the righting air cylinder to conduct clamping or loosening. The temperature controller insulation post assembling device is provided,and the blank of temperature controller insulation post staggered assembling on the market is filled up.

The invention specifically relates to a tumor-targeting nano-micelle, a preparation method and an application as a drug carrier. Aiming at the defect of poor selectivity of traditional chemotherapy methods, the purpose of the present invention is to design a drug delivery carrier with multi-functional targeting effect and a sonodynamic effect, so as to improve the delivery efficiency of anti-tumor drugs. Based on the above technical purpose, the present invention provides a multifunctional targeted nano-drug delivery system with chondroitin sulfate as the backbone, with water-soluble chondroitin sulfate as the basic skeleton, and rhein and lipoic acid as hydrophobic modifications. Nanomicelles are small in size and have good drug loading effect and encapsulation efficiency. The disulfide bonds on the surface of nanomicelles can be specifically broken after reaching the tumor site, thereby achieving targeted release; nanomicelles can promote the ability of rhein to generate active oxygen under the stimulation of ultrasound, effectively improving the antitumor drug efficacy. utilization rate. The tumor-targeting nanomicelle provided by the invention has good application prospects as an antitumor drug carrier.

The invention discloses an aerospace anti-latching circuit. The aerospace anti-latching circuit can effectively solve an anti-locking problem of a large-current module, has the advantages of simple and reliable circuit and less components, and is convenient for multiple paths and integral use in large quantities. A high-performance operational amplifier and a sampling resistor are firstly adopted to finish the sampling of a load current signal, the load current signal is converted into corresponding voltage, current-limiting time setting is finished through a one-order RC (Resistance-Capacitance) circuit, then, and the voltage and preset current-limiting voltage are compared so as to control the enabled end of a power supply module to finish the power-up and off control of the power supply module to realize the protection of the load.

The invention relates to a low molecular heparin-glycyrrhetinic acid polymer and its synthetic method and application. The synthetic method comprises the following steps: firstly synthesizing low molecular heparin-adipodihydrazide; synthesizing glycyrrhetinic acid succinate; preparing an active ester solution of glycyrrhetinic acid succinate; and finally synthesizing the low molecular heparin-glycyrrhetinic acid polymer. According to the invention, heparin is used as a water-soluble skeleton material, and glycyrrhetinic acid is used to carry out lyophobic modification on the water-soluble skeleton through succinic anhydride and adipodihydrazide used as linkers so as to prepare a glycyrrhetinic acid-mediated nano-carrier material with targeting capability. The heparin-glycyrrhetinic acid polymer has good biocompatibility, biodegradability and non-immunogenicity. Prepared hepatocyte-targeted drug-loaded nano-micelles have high entrapment rate and drug loading capacity, have excellent slow-release property, can enhance drug treatment efficacy and reduce non-specific toxic and side effect, and have a good application prospect.

The invention discloses an optical fiber distribution type multi-point online gas monitoring system and a main engine of the optical fiber distribution type multi-point online gas monitoring system. The optical fiber distribution type multi-point online gas monitoring system comprises the main engine and a monitoring probe distributed on each monitoring point, wherein the main engine is internally provided with a laser device; an output end of the laser device is connected to an input end of an output optical switch; the output end of the output optical switch is connected to each corresponding monitoring probe through an input optical fiber; each monitoring probe is connected to the corresponding input end of an input optical switch arranged in the main engine by an output optical fiber; the output end of the input optical switch is connected with an infrared photoelectric detector; the main engine is internally provided with a control module for controlling the output optical switch and the input optical switch to strobe and set a corresponding light path of each monitoring probe. According to the optical fiber distribution type multi-point online gas monitoring system and the main engine of the optical fiber distribution type multi-point online gas monitoring system, the main engine adopts the optical switches to realize time sharing multiplex of laser; under the condition of the laser devices with the same power, an optical fiber sensor can be distributed further; furthermore, only a single infrared photoelectric sensor needs to be arranged behind the output optical switch, so that the cost is reduced.