62 results about "Activity regulation" patented technology

The invention relates to a micro-interface enhanced reactor bubble scale structure-activity regulation and control model building method. The diameter dmax of the largest bubble of a micro-interface enhanced reactor and the diameter dmin of the smallest bubble of the micro-interface enhanced reactor serve as independent variables, the average diameter d32 of the bubble Sauter serve as a dependentvariable, and a numerical relationship is built; based on the Kolmogorov-Hinze theory, the relationship between the diameter dmax of the largest bubble of the micro-interface enhanced reactor, the diameter dmin of the smallest bubble and the parameters of the reactor is built. According to the method, the reactor bubble scale is associated with the structural parameter, the operation parameter andthe physical property parameter of the reactor by using specific numerical relationship, the numerical relationship has the guiding significance for the design of the reactor and can be applied to avariety of reactors, the versatility is good, by means of a bubble scale regulation and control model built through the method, by adjusting the structural parameter and the operation parameter of thereactor, and the maximization of energy efficiency and material efficiency in the reaction process can be achieved, or under the condition that reaction targets, energy consumption and material consumption are given, a high-efficiency reactor structure is designed.

The invention discloses a micro-interface enhancement reactor reaction rate structure-activity regulation and control model modeling method. Based on the Levenspiel theory, a reaction rate structure-activity model suitable for a micro-interface enhancement reactor is constructed. According to the invention, the reaction rate structure-activity regulation and control model constructed through the method can intuitively make out the effects of the bubble diameter, gas-liquid mass transfer coefficients, the mass transfer resistance and the like on the reaction rate; the bubble diameter of a reaction system, the reaction efficiency (energy efficiency and material efficiency), the physical and chemical properties of the system, micro-interface characteristics, mass transfer characteristics andthe reactor structure are correlated through a mathematic method; the energy efficiency and material efficiency of a reaction process are maximized by adjusting structural parameters and operating parameters; and alternatively, a reaction target (mission), energy consumption and material consumption are given, the efficient reactor structure is designed.

The invention, belonging to the technical field of air environmental pollution treatment, biofiltration and environmental pollution treatment, discloses a method for removing volatile organic chemicals (VOCs) by using nano Na2Ti6O13/TiO2 UV light catalytic oxidation cooperating with biofiltration. The method comprises the following steps that: organic waste gases enter into a photocatalytic device through a spray tower for catalyzing, then the gases enter into a biofiltering tower for filtering from the bottom of the biofiltering tower, wherein, the organic waste gases enter into the photocatalytic device for catalytic reaction, and partial VOCs are subject to photocatalytic oxidation by a nano Na2Ti6O13/TiO2 catalyst to form a water-soluble compound; in the biofiltering tower, the rest VOCs are degraded into CO2 and water and then discharged by specific biological bacterial species, and the biofiltering tower is communicated with a microbe activity regulation system to regulate the activity of the bacteria. The invention can efficiently decompose the VOCs in industrial waste gases, and can widely applied in treating the industrial gases containing VOCs.

A prediction and stimulation system or method is provided for neurological disorders characterized by a local dysfunction in neuronal activity regulation. An array of electrodes detects neuronal electrical activity of selected brain region. A detection module detects in each electrode changes in electric field and neuronal activity. A prediction module predicts for each electrode abnormal regimes determined by neurological disorder. A neuromodulation module interfaced with the electrodes selects one or more electrodes in the array where a predefined threshold has been exceeded and stimulates the brain region through each of these selected electrodes using an intermittent therapeutic stimulation pattern with a frequency between 150 and 200 Hz. The provided therapy allows for seizure prediction and detection with high accuracy, potential low risk and increased battery life. The flexibility of the method and system allows it to be used in different neurological disorders by tuning the parameters using a calibration procedure.

An infection spread prevention support system includes an examination terminal and an infection spread prevention support server. The examination terminal includes an examination information acquisition unit that acquires examination information to examine the infection of an infectious disease in subjects and a transmission and reception unit that transmits the examination information to the infection spread prevention support server. The infection spread prevention support server includes a receiving unit that receives examination information, an infection determination unit that determines the presence or degree of infection of the infectious disease using the examination information, an activity regulation information generation unit that generates activity regulation information to regulate the an activity of the infected patient based on infection determination information, which is a determination result of the infection determination unit, and information regarding the subjects, and an output unit that outputs the activity regulation information.

The invention discloses a gene expression vector for adjusting and controlling NF-kB activity in cells as well as a regulation and control method and application of the gene expression vector. The vector comprises two sequence elements, a promoter sequence and an miRNA coding sequence, wherein the promoter sequence is used for adjusting and controlling gene expression, and the miRNA coding sequence is located at the downstream of a promoter; the promoter sequence is formed by a section of NF-kB trapper sequence and a minimal promoter sequence; the miRNA coding sequence is the miRNA coding sequence capable of encoding and targeting NF-kB miRNA. By transfecting the gene expression vector, the NF-kB activity in the overactive cells can be mildly and effectively reduced, and the activity of normal cells is not obviously influenced, so that the side effect is avoided. The regulation and control method of the gene expression vector is simple, rapid and effective; and the gene expression vector is used for preparing an NF-kB activity regulation and control reagent or a drug molecule for treating diseases closely related to NF-kB overactivity and is taken as a novel gene treatment reagent.

The present invention discloses an acid soil polytropic conditioning improvement method. The method comprises the steps of: (1) performing plough of soil by employing a hydraumatic overturning ploughmachine, and performing natural ventilation for 3-5 days; (2) uniformly scattering decomposed manures on the ploughed soil, performing sun exposure for 2-3 days, and employing the hydraumatic overturning plough machine again to perform plough of soil; and (3) uniformly spraying a dilute soil conditioner on the soil ploughed again, and finally employing the hydraumatic overturning plough machine for plough, wherein the soil conditioner raw materials comprise ore, microbial flora, polyacrylamide, phenolic resin, polymethyl methacrylate, shuck powder, polyvinyl alcohol, polyvinyl acetate, ammonium sulfate, rice husk carbon, flue gas desulfurization gypsum, Chinese medicine residues, bagasse and maize straws; a mode for dual regulation through combination of biology and chemistry is employed to perform soil improvement to achieve various effects of PH value regulation of the obstacle soils, micro-ecology regulation, granular structure regulation, solidified nutrient element activity regulation and resorption passivation soil harmful metal elements.

L-Arginine or L-lysine is produced by culturing a coryneform bacterium having an L-arginine- or L-lysine-producing ability and modified so that glutamine synthetase activity is enhanced, e.g., a coryneform bacterium which is modified so that activity regulation of glutamine synthetase by adenylylation is eliminated, in a medium to produce and accumulate L-arginine or L-lysine in the medium and collecting the L-arginine or L-lysine from the medium.

The invention discloses a method for cultivating low-cadmium accumulated rice and use of related materials. The method for cultivating low cadmium accumulation rice comprises inhibiting or reducing the expression of OsCd1/2 gene in the target rice and obtaining low-cadmium accumulated rice, and the target rice is the rice containing the OsCd1/2 gene. The accumulation of cadmium in the low-cadmiumaccumulated rice is less than the accumulation of cadmium in the target rice; the OsCd1/2 gene encoding name is OsCd1/2 protein, OsCd1/2 is a) or b): a) protein having an amino acid sequence of SEQ IDNo. 2 or SEQ ID No. 4; and b) protein derived from a) and obtained by substituting and/or deleting and/or adding one or several amino acid residues to the amino acid sequences represented by SEQ ID No. 2 or SEQ ID No. 4 and having the biological cadmium accumulation activity regulation and control. The method can obtain the low-cadmium accumulated rice and reduce the food risk.

The present invention provides an E.tenella TERT associated protein gene, and particularly relates to applications of the protein in telomerase activity regulation, wherein the protein has a negative regulation effect on the E.tenella telomerase activity, and develops the new research field for deep research on cell and molecular biology characteristics of coccidian and finding of new chicken coccidian preventing and treating drugs, vaccine acting target sites and the like. According to the present invention, the advantages of high efficiency and practicality are provided, a plurality of positive interaction proteins can be obtained through the yeast two-hybrid screening and verification so as to easily find the new function protein, and the method of the present invention is mature and is easy to operate compared with the comparative analysis, the proteomics, the transcriptomics, and other technologies; and the E.tenella virus transforming vector-mediated ribozyme provides the simple and easy-performing method for the research on the functions of the gene in the insect body.

The invention discovers a transcriptional functional non-coding RNA gene having the capability of keeping nitrogen fixing activity of a strain for the first time. The invention discovers that the gene can specifically respond to an external nitrogen signal, participate in the nitrogen fixing enzymatic activity regulation of nitrogen fixing pseudomonas stutzeri and keep the efficient nitrogen fixing capability of the strain, thereby being applicable to obtaining a gene engineering strain having efficient nitrogen fixing capability.

The invention relates to a fungus cellulose enzyme system constitution/characteristic regulation gene and application thereof. Nucleotide sequences are demonstrated in SEQ ID No.1 or SEQ ID No.4. The invention further relates to fungus cellulose enzyme activity regulation factors coded by fungus cellulose enzyme activity regulation genes, and the application of the fungus cellulose enzyme activity regulation genes in preparation of special fungus cellulose enzyme. Amino acid sequences are demonstrated in SEQ ID No.2 or SEQ ID No.5. The fungus cellulose enzyme activity regulation genes and the fungus cellulose enzyme activity regulation factors can be used for regulating enzyme activity of cellulose enzyme in fungus. After a knockout box replaces the fungus cellulose enzyme activity regulation genes, compared with original strains, the enzyme activity of cellulose enzyme can be changed about 20% so as to meet requirements of various industries for the enzyme activity of different cellulose enzyme.

The present invention reveals process and utensil for taking pearl from living pearl shell. The process includes sex gland treatment and activity regulation of the pearl shell before taking pearl, discharging pearl and sealing. Taking pearl with opening tool can take out pearl from living pearl shell while ensuring the vitality of the shell. The present invention makes it possible for producing several pearls repeatedly with one identical pearl shell. After taking out one pearl, one pearl core in the size similar to that of the taken pearl may be implanted for producing even large pearl, and the re-implanted pearl core is less likely repulsed and extruded resulting high core retaining rate.

Belonging to the technical field of medicine, the invention in particular relates to an amide TGR5 agonist compound shown as formula (I), its pharmaceutically acceptable salts, esters, stereoisomers, solvent compounds or prodrugs, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, X, Y, Z, and ring A are defined as the specification. The invention also relates to a preparation method of the compounds, pharmaceutical preparations, pharmaceutical compositions, and application of the compounds in preparation of drugs for treatment and/or prevention of TGR5 activity regulation related diseases. (formula (I)).

The invention relates to a preparation method of an insect body polypeptide plant physiology conditioning agent. The method comprises the following steps: 1, grinding insect bodies, adding the ground insect bodies into an alkaline solution with the concentration of 0.5-85%, and hydrolyzing proteins and oils of the insect bodies at 0-120DEG C to obtain a solution containing insect peptides, amino acids, active factors and fatty acids; 2, filtering the obtained solution to remove insoluble insect shells, and adding an acid to a solution obtained after the filtration in order to neutralize; and 3, filtering the insect polypeptide solution obtained in step 2 to remove insoluble substances in order to obtain the insect body polypeptide plant physiology conditioning agent. The steps of the preparation method of the insect body polypeptide plant physiology conditioning agent are simple; and the insect bodies are hydrolyzed to form peptides, active factors, amino acids and fatty acids, so the peptide plant physiology conditioning agent prepared in the invention has the characteristics of plant growth activity regulation, comprehensive amino acids, high efficiency and rich nutrition, and has an obvious fattening effect on crops.

The invention discloses an olive waste material organic fertilizer, which is prepared from the following ingredients in parts by weight: olive fruit residue, olive leaves, olive branch wood vinegar liquid, rice bran powder, mushroom residue, polyacrylamide, bacillus marinus, bacillus thuringiensis, phanerochaete chrysosporium, rape seed cake, modified biochar, polyvinyl acetate, Epsilon-polylysine, propionyl brassinolide and ammonium molybdate. The organic fertilizer is produced by sufficiently utilizing olive fruit residue and olive leaves; the organic fertilizer has rich nutrition and high fertilizer effect; the fertilizer is favorable for the growth and development of the crop root systems; the soil conditions can be effectively improved, so that the soil becomes loose and fertile; thefertilizer is favorable for the cultivation and the crop root system growth and development; the production increase is promoted; the good regulation and improvement effects are achieved on the soil;various effects of soil PH value regulation, micro-ecology regulation, aggregate structure regulation, fixed nutrition element activity regulation, soil harmful metal element adsorption removal and passivation and the like are achieved.

The invention discloses a high-scorch-resistance peroxide curing system rubber composition and a preparation method thereof. According to the method, a radical activity regulation technology is utilized, an anti-scorching agent is added in the formula of a peroxide curing system to regulate the radical activity generated in decomposition of peroxide in the system, the effects of preventing occurrence of rubber crosslinking reaction at low temperature and promoting or not influencing rubber crosslinking reaction at high temperature can be achieved, excellent scorch resistance is achieved, and the mechanical performance of rubber is not influenced. The rubber composition prepared by the method has excellent scorch resistance and high mechanical performance retention rate, is simple and efficient, and is easy to operate, little in usage of the anti-scorching agent and low in cost. The prepared rubber composition peroxide is cured.

The invention discloses a frozen tender fish ball based on endogenous enzyme activity regulation and a processing method thereof, and belongs to the technical field of food processing. The method disclosed by the invention comprises the following steps: thawing frozen minced fillet, performing air chopping, performing salt chopping, performing mixed chopping, performing forming, performing gelling, performing curing, performing cooling, and performing quick freezing so as to obtain the frozen tender fish ball, wherein glucolactone is added in the step of mixing and chopping; the gelation is that the formed fish balls are gelated in a water bath at 65-70 DEG C for 3-8 minutes, so that the center temperature reaches 50-53 DEG C, and the pH value reaches 6.6-6.3; and carrying out water bath at 55-60 DEG C under the condition that the pH value is 5.8-6.2, and gelling for 15-20 minutes. According to the method disclosed by the invention, the problem that the soft, tender and smooth texture can be realized only with high water content is solved, and the prepared frozen tender fish balls have various sensory scores of 8.86 points or above, the water holding rate of 81.5% or above, the gel strength of 55-75 g.cm, the hardness of about 1000, the chewiness of 740-870, the elasticity of 0.46-0.57, good freezing resistance and good taste. The water binding capacity and the sense organ are basically not reduced after five times of freeze thawing.