144 results about "Cavitas nasi" patented technology

Chronic rhinosinusitis and other bacterial sinus conditions may be treated by applying a solvating system containing a surfactant to a bacterial biofilm in a nasal or sinus cavity, disrupting the biofilm, and applying a protective layer of a polymeric film-forming medical sealant.

A device for cleaning nasal membranes comprising a head that is inserted into a nostril. Fluid is pumped from a reservoir stored in a body of the device onto the membrane. The head rotates to remove debris from the membrane. A vacuum pump suctions the sprayed fluid and the debris into inlets and stores the used fluid in a chamber in the body.

This invention provides a bioresorbable foam packing device for post-operative use, especially to separate and prevent adhesions between mucosal surfaces in the nasal cavity, to help control minimal bleeding, and to prevent lateralization of the middle turbinate.

The present invention relates to the field of medical devices used in the procedures of orotracheal or nasotracheal intubation. Oral or nasal endotracheal intubation procedures are commonly employed to secure a controlled airway and to deliver inhalant oxygen, anesthetic gases, and other therapeutic agents into the trachea and lungs of human and veterinary patients. Such intubation procedures carry a significant risk of dental injury resulting from contact between the laryngoscope blade used for visualization during intubation. The present invention provides an apparatus to reduce dental injury including a modified laryngoscope blade and a disposable insert which is designed to be received and retained in a single step by the modified laryngoscope blade. The disposable insert may be quickly secured by the user, and reduces both direct pressure and shear forces on the maxillary incisor teeth when the laryngoscope blade is placed in a patient's mouth during intubation.

Embodiments of the present invention include an insertion aid device with a handle, a tongue depressor, a tracheal suction catheter guide, and a guide with a recess formed by a pair of prongs. The guide may be configured to accommodate the cross-sectional shape of a tracheal suction catheter, a nasogastric tube, or an orogastric tube. The tracheal suction catheter guide may include a connection port configured to couple to an in-line suction catheter. A light source may be included with the insertion aid device.

A filtering assembly in nasal cavities includes a connector with two rings connected by a link, and two filtering members are securely connected to the two rings. The two filtering members are inserted into the wearer's nasal cavities so as to effectively filter foreign objects from entering to the wearer's lungs.

The nasal cavity administrated huperzine preparation consists of huperzine as effective medicine component, lauryl azatroketone and other infiltration promoter and other assistants. It is used for treating senile dementia and memory dysfunction and raising memory and learning capacity. It has high mucous membrane penetrating property and high brain targeting property and each administration can lead 80-500 microgram of huperzine into body.

The present invention discloses a COVID-19 nucleic acid test sampling kiosk having a positive pressure and a disinfection apparatus, comprising a base and a cabinet body fixedly mounted on the base. Barrier glass is provided on at least one side surface of the cabinet body; two through holes are provided on the barrier glass, and are both connected to rubber extension gloves; a glove conveyor anda glove withdrawer are mounted on both sides of the barrier glass, respectively; rolled glove belts are mounted on the glove conveyer and the glove withdrawer by means of rolling shafts; and the barrier glass is provided with roller sealing strips on the upper and lower sides of the rolled glove belts, respectively. By means of a physical barrier, medical workers are protected from being infectedby sprays disseminated from oral cavities and nasal cavities of patients during nucleic acid test sampling. By means of a positive-pressure efficient filter air conditioning system, non-filtered external air is prevented from flowing in to reduce the infection risk of doctors by aerosol and to improve the working temperature in the cabinet body. By means of a disinfectant spray apparatus, gloves and the barrier glass are disinfected before and after each test sampling to reduce the risk of cross infection between the patients.

The invention relates to a recombinant Newcastle disease virus vector novel coronavirus vaccine candidate strain as well as a construction method and application thereof, and belongs to the technicalfield of genetic engineering vaccines. According to the vaccine candidate strain disclosed by the invention, a Newcastle disease virus LaSota strain is used as a carrier, and a mutated novel coronavirus S gene (C3756T, BamHI site is removed) is inserted between a P gene and an M gene of the Newcastle disease virus LaSota strain; and the nucleotide sequence of the mutated novel coronavirus S gene is shown as SEQ ID NO. 1. The recombinant Newcastle disease virus vector novel coronavirus vaccine candidate strain provided by the invention is safe, effective and low in production cost, can stimulate an organism to generate mucosal immunity through nasal cavity inoculation, and has important application value and outstanding public health safety significance.

The invention discloses a nasal polymer gel filling material and a preparation method thereof. The nasal polymer gel filling material is prepared from the following raw materials: gel and a crosslinking agent which is 0.1-2% of the mass of the gel. The preparation method comprises the following steps: adding the crosslinking agent to a water solution of gel to obtain a mixed solution; carrying out crosslinking reaction under the condition at 40-80 DEG C to obtain modified gel; soaking the modified gel into distilled water for 12-48 hours; replacing the water once at an interval of two hours; and carrying out freeze drying, so as to obtain the nasal polymer gel filling material. The gel filling material forms a compressed state when being placed, and is easy to put in, and light in adhesion with tissues, so that the expanded filling material is soft, and not easy to be extracted, and does not lead to adhesion of a nasal cavity. The inhibition ratio of the filling material on microorganisms such as staphylococcus aureus and escherichia coli can be up to over 90%, prevention of local infection is facilitated, and the anti-inflammatory action after chronic sinusitis-nasosinusitis surgery is improved.

The invention provides a sacculus medicine-spraying device for treating nasosinusitis or allergic rhinitis. The sacculus medicine-spraying device comprises an inflatable sacculus, a sacculus inner pipe and a sacculus catheter, wherein the sacculus inner pipe penetrates through the sacculus and extends axially; and the far-end opening of the sacculus catheter is ended in the sacculus. The sacculus medicine-spraying device provided by the invention has the advantages that the prepared effective treating medicine liquid or gelatinous or powdery solid particles can be conveyed to the diseased part of the paranasal sinus, and the cavity part of the frontal sinus and / or the maxillary sinus is used as a medicine storage device, so that the diseased part can be treated by medicines in enough-long treatment period. The sacculus medicine-spraying device also has the advantages that effective medicines are uniformly sprayed to the diseased part by minimally invasive surgery; the medicines stored on the frontal sinus and the maxillary sinus can be conveyed to the diseased part continuously in time along with the swinging of the cilium of the nasal cavity and the flowing of mucus of the nasal cavity; and before the stored medicines are metabolized, the medicines can be directly and continuously fed to the diseased part, and the treating effect of common medicine feeding is greatly improved.

The invention provides a novel nasal irrigator and a nasal irrigation device, and belongs to the nasal cavity cleaning field. The novel nasal irrigator comprises a spraying head, a conveying tube, a sealing structure, a conveying device and a housing. The housing comprises an installing cavity, the conveying device is positioned in the installing cavity, one end of the conveying tube is positioned in the installing cavity, and the other end of the conveying tube stretches out of the housing. The sealing structure is positioned between the housing and the spraying head. The conveying tube is rotatably connected with the conveying device. The conveying tube rotates along an axis thereof relative to the conveying device. The spraying head is positioned at one end, far from the conveying device, of the conveying tube. The nasal irrigation device comprises the novel nasal irrigator. According to the novel nasal irrigator, the sealing structure is disposed between the conveying tube and the housing, liquid backflow can be effectively prevented, dry working environment in the housing can be maintained all times, working of the novel nasal irrigator can be prevented from being influenced, liquid in a transfusion device can also be prevented from being influenced, and the nasal cavity can be effectively cleaned by the novel nasal irrigator.

There is provided a device comprising a funnel connected to a suction tube connectable to a suction device, the funnel comprising a reversibly inflatable portion. The device is preferably a nasopharangeal device suitable for insertion through a mouth of a patient, the funnel being formed so as to be sealably locatable in or around the nasopharangeal opening of the patient. There are further provided methods for protecting an airway of a patient from nasal-derived liquid and / or applying medicament and / or packing to a nasopharynx, oropharynx or nasal cavity of a patient using the inventive device. The device provides a system in which misting of endoscopic lenses is reduced or prevented. Embodiments of the device allow for the strength of applied suction to be controlled.

The invention relates to black cumin seed oil nose drop and a preparation method thereof. The black cumin seed oil nose drop is prepared from black cumin seed oil or from black cumin seed oil, scabrous mosla herb, herba ephedra, radix angelicae, violet magnolia, centipeda minima, schizonepeta and radices sileris in a compounding manner. The black cumin seed oil nose drop disclosed by the invention is used for directly acting on the mucosa of the nasal cavity, becomes effective rapidly, and can relieve inflammatory cell infiltration of the nasal mucosa caused by rhinitis and nasosinusitis and inhibit hyperplasia of connective tissues below the mucosa so as to improve nasal obstruction caused by swelling of the nasal mucosa, so the black cumin seed oil nose drop is suitable for treating various rhinitis and has a better effect than clinical commonly-used biyanling pills, centipeda minima nasal drops and the like.

The invention provides a paranasal sinus tube stent and a preparation method thereof. The preparation method comprises the following steps: providing a preset thermoplastic degradable polymer, printing the thermoplastic degradable polymer into a thin sheet on an XOY plane by adopting a 3D printing technology, curling the thin sheet around a preset reference axis to form an annular structure, pre-fixing, and carrying out heat treatment shaping on the annular structure to obtain a hollow stent, and forming a porous drug carrying layer on the surface of the hollow stent, and carrying out hole sealing treatment on the porous drug carrying layer to obtain the sinus canal stent. The preparation method provided by the invention is not limited by the precision of a fused deposition type 3D printerinstrument, and ensures the consistency of forming conditions of all parts of the stent, so that the stent has good elasticity, the stent can be effectively prevented from escaping from a matrix in adeployment process, subsequent sudden release of drugs can be effectively prevented, and meanwhile, the problem of insufficient drug carrying capacity is also avoided, and thus the probability of medical accidents such as secondary blockage caused by the fact that granulation tissues of the nasal cavity grow into the space of the nasal cavity is prevented.

A noninvasive, brain cooling method and device for cerebral cooling via a patient's nasopharyngeal cavity, is described. Thermal conductive nasal prongs are inserted into a nasal cavity and are cooled by thermoelectric cooling elements. An outward air driving fan inside the device drives a cold air current through the nasal and oral cavities. Heat transfer between the cold air and the surface of the nasal cavity cools the nasal cavity, which in turn, cools a patient's brain. Real-time temperature sensing data provides feedback for closed-loop cooling control.

The invention relates to a disposable intranasal brain targeted drug delivery device. The disposable intranasal brain targeted drug delivery device comprises a drug deliverer, wherein the drug deliverer comprises a container which is provided with an inner cavity and is used for storing a preparation, a guide pipe which is communicated with the container and is used for guiding the preparation in the container into a nasal cavity, and an atomizing spray head arranged at one end of the guide pipe; one end, provided with the atomizing spray head, of the guide pipe can stretch into a nasal cavity smelling region above the horizontal position corresponding to a concha nasalis media of the meatus nasi communis of a human body to efficiently transmit the preparation into the nasal cavity smelling region, and then the preparation is directly adsorbed into a brain to express the treatment effect in a central nervous system.

The present invention relates to a medical device for intranasal delivery of a medicament. The medicament may be any type of medicament suitable for nasal administration and delivery in the form of a spray. The present invention ensures that a complete dosage of the medicament is delivered, especially to specific areas in the nasal cavity, such as the rear of the nasal cavity where the SPG is located.

The invention provides a nasal cavity circulating drug delivery device. The nasal cavity circulating drug delivery device comprises a shell, a liquid storage tank, a drug delivery mechanism and a circulating mechanism, the interior of the liquid storage tank is divided into a stock solution storage cavity and a return liquid storage cavity, and a one-way valve is arranged between the stock solution storage cavity and the return liquid storage cavity; the dosing mechanism comprises a dosing spray head, a dosing pump, a first infusion pipeline and a second infusion pipeline, and liquid in the stock solution storage cavity is pumped to the dosing spray head by the dosing pump; the circulating mechanism comprises a suction head, a circulating pump, a first liquid return pipeline and a second liquid return pipeline, and liquid sucked by the suction head is pumped to the return liquid storage cavity by the circulating pump; a filter part is arranged in the return liquid storage cavity, and liquid sucked by the suction head is filtered by the filter part and then flows back to the stock solution storage cavity from the return liquid storage cavity through the one-way valve. According to the technical scheme provided by the invention, the effective staying time and the distribution space of the liquid medicine in the nasal cavity are improved through circular administration, medicine absorption is facilitated, and nasal cavity water inhaling and nasal cavity damage caused by water pressure are effectively prevented.

The invention relates to nasal mucosa repair human-like collagen gel. The nasal mucosa repair human-like collagen gel comprises, by weight, 0.1-1% of human-like collagen, 0.5-1% of carbomer, 20-30% of glycerinum, 0.1-0.5% of allantoin, 0.005-0.02% of sodium hyaluronate, 0.09-0.1% of sodium hydroxide, 0.1-0.5% of ethylparaben, 0.01-0.05% of menthol, 0.4-0.6% of polysorbate 80, and the balance water. The human-like collagen gel can remarkably accelerate transdermal absorption of the human-like collagen when being applied to the skin of a nasal cavity with damaged mucosas, and therefore, by adoption of the human-like collagen gel, better nourishing can be provided, mucosa cell regeneration is stimulated, and damaged nasal cavity mucosa repair is promoted.

The invention discloses a medicine composition for treating rhinitis. The medicine composition for treating rhinitis comprises the following constituents: micromolecular active peptide, chlorhexidine gluconate, glycerol, hydrogenated castor oil, mint essence and fragrant rice essence. The medicine composition disclosed by the invention is used as a spray, high in bacteriostatic action, capable of inhibiting bacteria such as staphylococcus aureus, candida albicans and escherichia coli, suitable for cleanliness and disinfection for nasal cavity, remarkable in effects on people with nasal obstruction, turbid nasal discharge, sneezing, headache, hyposmia, mycteroxerosis and the like due to acute and chronic rhinitis, allergic rhinitis, nasosinusitis, cold and the like.

The invention relates to a powder distributing and supplying device and a usage method thereof, and is characterized in that the powder distributing and supplying device comprises a mixing and dipping box, a peristaltic pump structure, a first hose, a second hose and a nasal plug; a filter cartridge is also rotationally connected in the lower end of a mixing chamber. The two ends of the filter drum are connected to the two inner walls of the mixing chamber through a first rotating shaft and a second rotating shaft respectively, one end of the second rotating shaft extends into the filter drum and is connected with a medicine pumping extension pipe bent downwards, and one end of the first hose is connected with the other end of the second rotating shaft and communicated with the second rotating shaft; The other end of the first hose is connected with the peristaltic pump structure, and the peristaltic pump structure is connected with the nasal plug through the second hose. The nasosinusitis can be treated in a dipping and autonomous inhalation mode, and a patient who cannot automatically inhale can be passively treated in a mode that liquid medicine is injected into the nasal cavity, so that the function of increasing the practical performance is achieved.

The invention relates to a medicinal preparation and a preparation method thereof and in particular relates to a compound Chinese medicament for treating cancer and a preparation method thereof. The compound Chinese medicament for treating cancer is produced into spray and aerosol, the sprayed mist-state liquid is mixed with negative oxygen ions to both act on the nasal cavity, or directly produced into oral solution. The medicament is prepared from fermentative cordycep fungal powder and ganoderma lucidum powder at a weight ratio of 1:(0.8-1.2). The preparation method comprises the following steps: weighing the fermentative cordycep fungal powder and ganoderma lucidum powder according to the weight ratio; sealing with deionized water and heating to 80-100 DEG C, extracting for 1 hour, and filtering to obtain an extract; sealing with deionized water and heating to 80-100 DEG C, filtering to obtain an extract; combining the two extracts, heating to 80 DEG C, concentrating into a medicinal concentrated solution; and cooling to normal temperature to prepare the medicinal concentrated solution of the compound Chinese medicament for treating cancer.

The invention relates to the technical field of medical images, and discloses a nasal cavity NKT cell lymphoma radiotherapy target area automatic sketching method and device, and the method comprises the steps: collecting a sketched nasal cavity NKT cell lymphoma CT image; preprocessing the CT image to obtain a deep learning data set; training the deep learning data set in a deep neural network model to obtain a nasal cavity NKT cell lymphoma sketching model; and preprocessing the clinical CT image, and inputting the preprocessed clinical CT image into the nasal cavity NKT cell lymphoma sketching model for sketching. The method and device solve the problem that in the prior art, due to the fact that the individual difference between patients is large, it is often difficult to define a universal template to meet the delineation requirement when existing deformation registration is adopted as a delineation method, and consequently the delineation precision is low.

The disclosed technology described pertain to collection swabs that are designed to capture and retain specimen, tissue, or fluids from a patient. The collection swabs are generally inserted into a desired location, such as a nasal cavity. During the process of insertion, a user maneuvers the collection swab and in the process dislodges and collects various specimen, tissue, or fluids from the patient. The collection swab utilizes specially designed distal or tip portions and / or sleeves or cages in order to capture and retain the specimen, tissue, and fluids. The various designs associated with the distal or tip portion and the sleeve or cages affect not only how much specimen, tissue, or fluids can be collected but also how much of the specimen, tissue, or fluids can be retained after the collection swab is removed from the patient. By obtaining the various specimen, tissue, or fluids, studies can be performed regarding the patient's health, for example, identifying the presence of specific virus such as COVID-19.

The invention provides a nasopharyngeal swab sampling assistor for a clinical laboratory, and belongs to the technical field of medical instruments. The nasopharyngeal swab solves the problems that sampling of an existing nasopharyngeal swab mainly depends on manual operation of medical staff, fatigue of the medical staff is accelerated due to large collection amount and long-time work, the depth of a cotton swab penetrating into a nasal cavity of a sampler cannot be well controlled due to tension for green medical staff, the cotton swab extends too deep during sampling, and a sampled person feels painful or the nasal cavity is abraded. The nasopharyngeal swab sampling assistor for the clinical laboratory comprises a shell with an opening in the right end; a working space is defined in the shell; a power mechanism for driving the assistor to operate is arranged in the working space; and sliding mechanisms driven by the power mechanism are arranged in the end walls of the upper side and the lower side of the shell respectively. The nasopharyngeal swab sampling assistor for the clinical laboratory is more convenient to use, labor-saving and higher in stability.

The invention relates to the technical field of medical devices, and discloses a rhinitis and flu therapeutic apparatus and a working method thereof. The rhinitis and flu therapeutic apparatus comprises an apparatus main body; a quartz glass tube which is arranged at the first end of the instrument main body and can be inserted into the nasal cavity; a ultraviolet lamp, wherein the ultraviolet lamp is arranged at the first end of the main body and is located at the bottom of the quartz glass tube to emit ultraviolet rays with multiple wavelengths, and the ultraviolet lamp emits ultraviolet rays with multiple wavelengths from inside to outside through the quartz glass tube; a heating sheet which is arranged at the first end of the apparatus main body and is connected with the quartz glass tube; a temperature sensor which is connected with the quartz glass tube and is used for detecting the temperature change of the quartz glass tube; and a control device which is electrically connectedwith the ultraviolet lamp, the heating sheet and the temperature sensor. According to the rhinitis and flu therapeutic apparatus disclosed by the invention, capillaries in the nasal cavity are expanded through heating, germs are exposed on the surface, ultraviolet rays are used for irradiating according to different symptoms of a user to kill the germs, and therefore, rhinitis and flu symptoms canbe relieved and treated.