Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

62 results about "Dietary interventions" patented technology

Customer health data intelligent management system and method

The invention discloses a customer health data intelligent management system and method, and belongs to the technical field of health data management. Basic data and health data are collected; the client inputs a daily menu and calculates nutrients; establishing a daily nutrient matrix based on nutrients, and identifying a diet mode; defining a taste space, and extracting taste features based on the seasoning use condition of the menu every day; integrating to form an input vector; establishing a personalized nutrition demand prediction model, and training to obtain nutrition constraints; retrieving the candidate recipes based on nutrition constraints, and performing taste matching to obtain recommended recipes; based on the menu selection records of the similar clients, the recommended menu is optimized; dynamically adjusting the recommendation strategy according to the score of the customer for the recommended menu to obtain an optimal menu; when the customer eats the optimal menu, the change of health data before and after diet intervention is calculated, and the intervention effect is quantified; nutrients needed by the client are adjusted based on the intervention effect, and the optimal menu is correspondingly adjusted.
Owner:DONGHAN MEDICAL TECH(CHANGZHOU) CO LTD

Momordica grosvenori instant coffee beverage for assisting in reducing uric acid and preparation method of momordica grosvenori instant coffee beverage

The invention discloses a siraitia grosvenorii instant coffee beverage assisting in reducing uric acid and a preparation method thereof, and belongs to the technical field of food based on the theory of homology of medicine and food. The coffee beverage is composed of instant coffee powder, a compound sweetening agent, coconut milk powder, milk powder and composite herbal powder in a specific proportion. The compound herbal powder is composed of poria cocos, peach kernels, dried tangerine or orange peel and momordica grosvenori which are selected from a medicinal and edible substance catalog. The herbal active ingredients and a coffee system are deeply fused by optimizing an extraction process, the dual regulation effects of inhibiting xanthine oxidase and promoting uric acid excretion are synergistically exerted, and the technical contradiction that common caffeine possibly affects uric acid excretion is effectively solved. The zebra fish in-vivo experiment proves that the level of uric acid can be remarkably reduced (Plt: 0.001), the improvement rate is as high as 17.63%, and a safe and effective daily diet intervention scheme is provided for people with hyperuricemia while the coffee flavor and convenience are provided.
Owner:GUANGXI ZHUANGYUAN PHARM TECH CO LTD

Rice starch ester as well as preparation method and application thereof

The invention belongs to the field of food processing, and particularly relates to rice starch ester as well as a preparation method and application thereof. According to the invention, by exploring the action rule of reaction time, reaction temperature, pH value and acid addition amount on modified rice starch ester, the content of resistant starch in rice starch is increased and the GI value is reduced through esterification modification, so that the rice starch with the function of regulating blood sugar level is obtained; the product also can significantly improve inflammation and fat accumulation symptoms caused by hyperglycemia; in a diet intervention experiment, both the CRS and the MRS show an effective reduction effect on the weight growth rate, the blood sugar level, the visceral organ index and the inflammatory factor content of the hyperglycemia mouse. The result shows that the CA / MA rice starch ester not only has the function of regulating the blood sugar level, but also can remarkably improve inflammation and fat accumulation symptoms caused by hyperglycemia, and has a positive effect on maintaining the overall health.
Owner:HARBIN UNIV OF COMMERCE

Method, medium and equipment for personalized diet recommendation of enteritis patient

The invention discloses a personalized diet recommendation method for enteritis patients, a medium and equipment. The method comprises the following steps: continuously collecting diet image data, physiological state time sequence data and subjective symptom feedback data; performing food material component deconstruction and cooking mode identification on the diet image through a convolutional neural network, and generating a structured diet vector; analyzing physiological state time sequence data by using a hidden Markov model, and constructing an individualized physiological rhythm map; establishing a symptom triggering condition probability matrix based on a multi-modal association mining algorithm; generating an exploratory diet scheme according to the real-time physiological state of the user and the conditional probability matrix; dynamically updating the conditional probability matrix through an online reinforcement learning mechanism; and finally, periodically outputting a personalized diet taboo list and a safety exploration list. According to the method, through the dynamic correlation analysis of fusing the time sequence physiological features and the dietary components, accurate matching of diet recommendation and individual intestinal tract state fluctuation is realized, and the individuation and adaptability of diet intervention are effectively improved.
Owner:FUJIAN UNIV OF TRADITIONAL CHINESE MEDICINE

Diet intervention system and method for different obesity

The invention relates to the field of obesity diet intervention, in particular to a diet intervention system and method for different obesity. The method comprises the following steps: firstly, acquiring data information and BMI measurement values of different measurable indexes and self-reporting indexes of each patient in a target set, verifying data information and BMI self-reporting values of different self-reporting indexes of each person in the set, respectively combining the self-reporting indexes and the measurable indexes, classifying the patients in the target set, and verifying the self-reporting indexes and the measurable indexes in the target set; the method comprises the following steps: acquiring a conceal index data information difference between a patient and a person in a conceal category, dividing the patient and the person into a plurality of conceal categories, obtaining conceal probabilities of the conceal categories according to the data information difference of the self-report indexes between the patient and the person in the conceal category and the difference between a BMI measurement value and a BMI self-report value, and constructing a neural network model based on each conceal probability. And verifying the authenticity of the data information of the to-be-tested person and performing diet intervention. The authenticity of the data information of the to-be-tested person can be accurately verified, and the rationality of diet intervention is improved.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Intelligent diet intervention control method and system

PendingCN120148765AMedical data miningNutrition controlNutritional IndicesNutrition
The invention relates to the technical field of health management, in particular to an intelligent diet intervention control method and system.The intelligent diet intervention control method comprises the following steps that heat, protein, sugar and sodium content data are extracted from a food database based on user health data and individual nutritional requirement parameters, difference values of multiple kinds of food under differential constraints are calculated respectively, and the difference values are calculated; deviation scores are formed through accumulation calculation, and a nutrition deviation score set is generated. According to the method, multi-level processing is carried out on food combination through step-by-step screening and dynamic optimization logic, key nutrition index deviation is extracted based on health data and individual demands, quantitative scoring is carried out, the degree of adaptation of food is determined, and diversity is ensured for deviation scoring, combination screening and variation processing steps. Meanwhile, a non-dominated relation is introduced to remove low-efficiency options, the quality of a recommendation scheme is improved, personalized sorting is performed in combination with user demand weights, food combinations are balanced among nutrition balance, health constraint and personalized demands, and the health management target is accurately met.
Owner:XINYI CITY PEOPLES HOSPITAL

Diet intervention method and system for crowd with cardiopulmonary health risk

PendingCN120356624ADigital data information retrievalNutrition controlData setHeart rate variability
The invention discloses a diet intervention method and system for crowds with cardiopulmonary health risks. The system comprises a database, an information acquisition module, a risk assessment module, a calculation module, a diet recommendation module, an auditing module and an information pushing module. The database comprises a personal information database, a suggestion database, a recipe database and a different-energy-level food intake database; the information acquisition module is used for acquiring intelligent bed sleep health data and personal information data in a database, and generating a personal user data set for the risk assessment module and the calculation module; wherein the sleep health data collected by the intelligent bed comprises but is not limited to the whole late heart rate, the respiration rate, the heart rate variability and the like; according to the invention, through combination of static and dynamic health data, through risk assessment and early warning, diet health management is carried out on crowds with cardiopulmonary health risks, and the problem that the public cannot effectively utilize knowledge to carry out self-health management actually is accurately solved.
Owner:KEESON TECH CORP LTD +1

Individualized lifestyle intervention for obesity management based on obesity phenotypes

PendingUS20250306033A1Organic active ingredientsMetabolism disorderPhysiologyLifestyle intervention
The present disclosure relates to methods and materials for assessing and / or treating obese mammals (e.g., obese humans). For example, methods and materials for using one or more interventions (e.g., individualized dietary interventions alone or in combination with pharmacological intervention(s)) to treat obesity and / or obesity-related comorbidities in a mammal (e.g., a human) identified as being likely to respond to a particular intervention (e.g., individualized dietary interventions alone or in combination with pharmacological intervention(s)) are provided.
Owner:MAYO FOUNDATION FOR MEDICAL EDUCATION & RESEARCH

Application of a branched-chain amino acid-restricted diet in the preparation of drugs for treating liver metastases of tumors

This invention discloses the application of a branched-chain amino acid (BCAA) restricted diet in the preparation of drugs for treating liver metastases of tumors. Through mouse model experiments, this invention found that restricting the intake of BCAAs (valine, isoleucine, and leucine) in the diet, or using the SCD1 inhibitor A939572, can significantly inhibit liver metastases of tumors, especially pancreatic cancer liver metastases. Experimental results show that a BCAA restricted diet or SCD1 inhibitor can reduce the number and volume of liver metastases and inhibit their growth. This invention also reveals its mechanism of action: BCAA restriction reduces the propionylation modification of SREBP1, downregulates the transcriptional expression of its target gene SCD1, and thus reduces lipid synthesis, thereby exerting an anti-tumor liver metastasis effect. This invention provides a novel dietary intervention strategy and drug target for the treatment of liver metastases of tumors.
Owner:AFFILIATED HOSPITAL OF JIANGSU UNIV

Compositions and methods for improvement and maintenance of weight loss

The present invention provides nutritional compositions for use in weight loss dietary interventions or in particular weight maintenance after dietary interventions, preferably after low calorie dietary interventions. The nutritional composition comprises one or more amino acids selected from the group consisting of proline, histidine, glycine and / or hydroxyproline, or a combination thereof, which can be used to assist in weight loss in obese subjects that are resistant to weight loss only by means of caloric limiting dietary intervention. In addition, the nutritional composition of the present invention may be used to help maintain the weight loss, particularly after dietary intervention.
Owner:SOCIETE DES PRODUITS NESTLE SA

Companion diagnostic method for use in the treatment of irritable bowel syndrome with dietary interventions or faecal microbiota transplant

The present invention provides a diagnostic method which may be used to determine the likelihood that a subject with Irritable Bowel Syndrome (IBS) will respond to treatment with an IBS intervention diet. In particular, the method may be used to predict, or determine the likelihood of, a positive response of the subject with IBS to treatment with an IBS intervention diet, especially to determine the likelihood that the dietary intervention may have a positive (i.e. beneficial) effect on the subject's GI tract, specifically the GI tract microbiota, or other symptoms or complications of IBS (e.g. reducing severity thereof). The method of the present invention is based on analysing the abundance of certain bacteria in GI tract samples, e.g. by nucleic acid analysis.
Owner:GENETIC ANALYSIS

Interaction method based on intelligent tableware system and intelligent tableware system

The invention relates to the field of intelligent tableware, in particular to an interaction method based on an intelligent tableware system and the intelligent tableware system. The intelligent tableware system comprises a display unit, at least one containing unit, a sensing unit and / or a communication unit, the sensing unit is used for collecting the bearing state of each containing unit, the communication unit is used for receiving the bearing state of each containing unit transmitted by a far end, and the display unit is used for displaying an interactive interface; the method comprises the steps of obtaining a dining mode selected by a user; calling a corresponding dining guide process according to the dining mode, the dining guide process comprising a plurality of dining process nodes having a preset sequence, and each dining process node corresponding to a different interactive interface; the bearing state of at least one containing unit is monitored in real time, the interaction interface of the current dining process node is updated according to the bearing state, and personalized and forward diet intervention is achieved.
Owner:CHONGQING MINGYUEHU INTELLIGENT TECH DEV CO LTD

Fermented tea with alcoholic liver injury protection function and preparation method thereof

The invention relates to the technical field of functional food processing, in particular to fermented tea with an alcoholic liver injury protection function and a preparation method of the fermented tea. The functional tea beverage is prepared by optimizing the fungus compatibility proportion, the fermentation condition and the subsequent blending process, and the method is provided for dietary intervention of alcoholic liver injury due to the regulation effect on hepatic cell oxidative stress and inflammatory factors. The preparation method comprises the following steps: mixing the lucid ganoderma, the phellinus igniarius, the grifola frondosa and pure water according to a weight ratio of 1: 30, carrying out water bath extraction at 90 DEG C for 2-4 hours, filtering, mixing extract liquids according to a ratio, and adjusting the pH value to 5.0-6.0; inoculating yeast into a YPD culture medium, culturing at 22-31 DEG C for 24-96 hours until the pH value is 5.0-6.5 to obtain a yeast liquid, inoculating the obtained yeast liquid into the extract liquid obtained in the step 1), fermenting at 28 DEG C for 72 hours, and adjusting the pH value to 5.5; and heating at 60-70 DEG C for 10-15 minutes to inactivate the yeast, filtering, and refrigerating and storing.
Owner:MICROBIOLOGY INST OF SHAANXI

Methods for the improvement and maintenance of weight loss

A nutritional composition for use in a weight loss dietary intervention or maintenance of weight, particularly following a dietary intervention, preferably a low caloric diet intervention. The nutritional composition contains one or more amino acids, or combinations thereof, selected from the group consisting of: proline, histidine, glycine, and / or hydroxyproline, that can be used to help the weight loss in obese subjects that are resistant to weight loss by caloric restricted dietary interventions alone. In addition, the nutritional composition can be used to help maintain the weight loss, particularly after dietary intervention.
Owner:SOCIETE DES PRODUITS NESTLE SA

A dietary intervention system for different obesity

The present application relates to the field of obesity dietary intervention, and particularly relates to a dietary intervention system for different obesity. The system first acquires data information of different measurable indexes and self-reported indexes and BMI measurement values of each patient in a target set, and data information of different self-reported indexes and BMI self-reported values of each person in a verification set, respectively combines the self-reported indexes and the measurable indexes, classifies the patients in the target set, and then divides the patients and the persons into multiple concealment categories, obtains concealment probabilities of the concealment categories according to differences in data information of the self-reported indexes between the patients and the persons in the concealment categories, and differences between the BMI measurement values and the BMI self-reported values, constructs a neural network model based on the concealment probabilities, verifies the authenticity of data information of a to-be-tested person, and performs dietary intervention. The present application can accurately verify the authenticity of data information of the to-be-tested person, and improve the rationality of dietary intervention.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

Key marker combination for individualized diet intervention decision and application thereof

PendingCN122050710AMedical data miningNutrition controlOverweight obesityRespiratory quotient
The invention provides a key marker combination for individualized diet intervention decision and application thereof. Specifically, three clusters based on a respiratory quotient (RQ) are found according to metabolic index change conditions before and after meals of people with normal body weight and overweight / obese people. In addition, key biomarkers for distinguishing the three clusters are also found; a prediction model constructed by using the key biomarkers can accurately divide subjects into three RQ clusters, and can be used for predicting a weight loss intervention result, so that the prediction model can be used as a reference for providing an individualized diet or exercise intervention decision. A system constructed according to the key marker is high in sensitivity and accuracy, used indexes are easy to obtain, and the key marker has a good clinical application prospect.
Owner:SHANGHAI INST OF BIOLOGICAL SCI CHINESE ACAD OF SCI

Broken sugar dietary therapy formula based on zaocys dhumnade or cobra and preparation method

The invention discloses a broken sugar dietary therapy formula based on zaocys dhumnade or cobra and a preparation method, and relates to the technical field of health preservation. The method comprises the following steps: S1, raw material pretreatment: treating sandworms: taking 1.5 kg of dry sandworms, removing sandbags, washing, and baking at 170 DEG C for 4 hours for later use; 135kg of zaocys dhumnade meat and 60kg of chicken are taken, washed and diced; taking 35kg of soybeans and 20kg of hericium erinaceus, washing and soaking for 2 hours; 2 kg of ginseng and 2 kg of dendrobe are taken and washed; 25 kg of dried scallops are taken and washed; s2, performing boiling and performing filling; aluminum cans are filled with the soup bases through an automatic filling machine (258 g per can), and the aluminum cans are sealed immediately; and S4, outer packaging: putting the sterilized tank body and the self-heating bag into an outer bowl, sealing with a film, and boxing. According to the invention, through the setting of a sugar-breaking dietary therapy method, the problems that the existing sugar-breaking or diet intervention product focuses on nutrient control and lacks systematic collaborative design and scientific proportioning for functional components (such as medicinal and edible active components) are solved.
Owner:GUANGXI GUIXIAOSHE AGRICULTURAL SCIENCE & TECHNOLOGY DEVELOPMENT CO LTD

Method and system for health intervention of diet structure based on physical data of obese children

ActiveCN121331379BNutritionEmergency medicine
The present application relates to the technical field of data processing and strategy optimization, and particularly relates to a diet structure health intervention method and system based on physical data of obese children. The present application firstly acquires physical data and nutrition data and groups children; further acquires intervention synchronism of each physical data according to deviation characteristics of each physical data compared with corresponding preset physical standard and similarity of changes in time domain of deviation characteristics of all physical data; further adjusts the diet structure of the target child according to the difference in intervention synchronism of each physical data of the target child and the children in the same group at the current period, in combination with the difference between the nutrition data and the preset recommended diet structure. By analyzing the individualized differences in the physical angle and the diet intake angle of the children, the diet structure of the children is continuously adjusted, the diet intervention adaptability is improved, and the intervention effect is ensured.
Owner:QINGDAO HONGZHU BIOTECHNOLOGY CO LTD

High-iron feed for preventing and treating Clostridium difficile infection in mice and application thereof

The present invention belongs to the field of feed technology, and discloses a high-iron feed for preventing and treating Clostridium difficile infection in mice and its application. The raw material composition of the high-iron feed is as follows in g / kg: casein 200, L-cystine 3, corn starch 397.5, maltodextrin 132, sucrose 100, cellulose 50, soybean oil 70, mixed vitamins 10, mixed minerals 35, and ferrous sulfate 0.4. The high-iron feed can be used as a dietary intervention for intestinal inflammation caused by Clostridium difficile infection in mice. Through animal experiments, it was found that the high-iron feed can effectively inhibit the colonization and germination of Clostridium difficile spores in mice, alleviate clinical symptoms such as weight loss, diarrhea, and hunchback caused by Clostridium difficile infection, increase the secretion of beneficial compounds such as tauroursodeoxycholic acid and trillium glycosides, reduce the production of inflammatory cells and inflammatory factors, and thus alleviate Clostridium difficile infectious enteritis. It provides important experimental data for the development of non-antibiotic therapy for Clostridium difficile, and has good application prospects and huge potential value.
Owner:XUZHOU MEDICAL UNIVERSITY

Soda water beverage added with nattokinase as well as preparation method and application of soda water beverage

The invention provides a soda water beverage added with nattokinase and a preparation method and application thereof, the soda water beverage added with nattokinase has a pH value of 7.8-8.2 and a carbonation degree of 0.8-1.2 g / L, and contains nattokinase, and the activity of the nattokinase is greater than or equal to 10,000 FU / L. The soda water beverage added with the nattokinase is applied to preparation of products for regulating PCSK9 activity, reducing the low density lipoprotein cholesterol LDL-C level in blood or preventing / assisting in managing obesity and related metabolic syndromes. The product is a beverage, a health food or a dietary supplement. The nattokinase can be used for specifically hydrolyzing the Ser153-Gly154 site of the PCSK9 protein, and the Ser153-Gly154 site of the PCSK9 protein can be specifically hydrolyzed. According to the beverage, the activity of nattokinase is protected by optimizing pH and a carbonation system, the intestinal absorption rate of the nattokinase is improved, and the function of PCSK9 is inhibited in a targeted manner so as to regulate blood lipid metabolism. Compared with an existing oral enzyme preparation, the oral enzyme preparation has high efficiency, stability and consumption convenience, and an innovative diet intervention scheme is provided for obesity and related metabolic diseases.
Owner:AFFILIATED HOSPITAL OF JIANGSU UNIV

Lactobacillus plantarum dx7, method for producing indolelactic acid and use thereof

The application provides a lactobacillus plantarum DX7 and a method and application thereof for producing indole lactic acid, relates to the field of food microbial technology, and the lactobacillus plantarum DX7 has been preserved in the Guangdong Microbial Culture Collection Center on June 12, 2025, and the preservation number is GDMCC NO.66498. The lactobacillus plantarum DX7 in the application is significantly activated under the stimulation of deep-line walnut inner seed coat polyphenol, and can efficiently convert tryptophan into ILA. Experimental results show that the ILA yield of the strain reaches 217.56 mu g / mL. Moreover, the strain and deep-line walnut inner seed coat polyphenol can significantly relieve the colon inflammation symptoms of a DSS-induced colon inflammation mouse by gavage. The application not only provides a new strategy for efficient biological preparation of the functional component ILA, but also provides a basis and potential solution for dietary intervention of inflammatory bowel disease.
Owner:KUNMING UNIV OF SCI & TECH

A medicinal and edible therapeutic composition with the effects of clearing lung, resolving phlegm, removing blood stasis and dissolving nodules

PendingCN122376680AFormularyHouttuynia
This invention discloses a food-medicine composition with the effects of clearing the lungs, resolving phlegm, dispersing blood stasis, and eliminating nodules, belonging to the fields of functional food therapy and traditional Chinese medicine lung conditioning technology. This invention completely abandons the defects of traditional low-dose health care formulas. All raw materials are strictly formulated according to the legally prescribed therapeutic doses in the Chinese Pharmacopoeia and the conventional dosages in traditional Chinese medicine clinical prescriptions for pulmonary nodules. It uses high doses of Houttuynia cordata and fresh Imperata cylindrica root as the core heat-clearing and nodule-dispersing principal herbs, combined with sufficient amounts of Platycodon grandiflorus, Citrus reticulata peel, and Citrus reticulata peel to clear the lungs and resolve phlegm; a high proportion of Lilium brownii, Polygonatum odoratum, and Ophiopogon japonicus to nourish yin and protect the lungs; and Prunus persica to invigorate blood and disperse blood stasis, constructing a three-level pharmacopoeia-compliant dosage system. This invention features a rigorous formulation, a balanced combination of hot and cold properties of the medicinal ingredients, and sufficient potency. It breaks through the technical bottleneck of traditional dietary therapy formulas that cannot deeply disperse stagnation. It can effectively intervene in the phlegm and blood stasis in the lungs, improve pulmonary nodules, and eliminate long-term symptoms of lung heat and excessive phlegm, chest tightness, and dry throat. Its efficacy can be verified through multiple dimensions, including human trials, animal pharmacology experiments, and real clinical cases. The technology is innovative and practical, and it can be used as a high-end conditioning food for sub-healthy lungs in the general public, as well as a long-term standardized dietary intervention program for people with pulmonary nodules. It has extremely high value for industrialization and promotion.

A pig immune function prediction system and method based on artificial intelligence

The present invention provides an artificial intelligence-based system and method for predicting the immune function of pigs, comprising a detection device for detecting intestinal flora detection data corresponding to multiple omics and detection result data of multiple metabolic markers of pigs under stress; an edge optimization decision device for performing feature extraction based on the detection result data to obtain metabolic characteristic data; a prediction and display device for simulating the relationship between the activity of key metabolic enzymes and the expression of immune effector molecules of pigs under stress based on the intestinal flora detection data to obtain metabolic immune interaction data, storing the metabolic immune interaction data in a metabolic immune database, determining the dose-effect relationship between functional amino acids and immune phenotypes based on the metabolic characteristic data and the metabolic immune interaction data stored in the metabolic immune database, obtaining the metabolic spectrum characteristics of pigs under stress, and predicting, generating and displaying amino acid ratios or dietary intervention strategies based on the metabolic spectrum characteristics.
Owner:SICHUAN ANIMAL SCI ACAD

Method and device for evaluating fetal distress risk based on saturated fatty acid intake and medium

The invention discloses a method and a device for evaluating fetal distress risk based on saturated fatty acid intake, and a medium. The method comprises the following steps: acquiring daily average saturated fatty acid intake data of a pregnant woman to be evaluated; comparing the intake with a plurality of preset risk threshold intervals, and determining a corresponding fetal distress risk level; and finally outputting an evaluation result containing the risk level. According to the method, objective dietary data and a rigorous statistical method are combined, and the association between saturated fatty acid and fetal distress is converted into a clear quantitative risk assessment standard, so that the progress of risk assessment from qualitative to quantitative and from fuzzy to accurate is realized; the problem that in the prior art, an individualized and quantitative fetal distress risk assessment tool for saturated fatty acid is lacked is solved. The invention provides a rapid, convenient and non-invasive risk screening tool, and provides a scientific basis for pregnancy diet intervention and clinical monitoring.
Owner:CHONGQING MEDICAL UNIVERSITY

Inflammatory bowel disease accurate diet intervention scheme generation method and system based on multi-modal data integration

The invention discloses an inflammatory bowel disease accurate diet intervention scheme generation method and system based on multi-modal data integration, and relates to the technical field of diet and health management. The method comprises the following steps: acquiring crowd health data from a plurality of data sets; analyzing and marking the acquired crowd health data; constructing an identification rule and consistency calibration model of the macroscopic phenotype combination features; constructing a biomics alignment data structure reflecting diet and lifestyle-clinical medication-disease outcome association; performing reliability weighting on the macroscopic phenotypic information of the individuals, and endowing each layer of data of different data sets with corresponding weights; constructing a multi-dimensional comprehensive data matrix; establishing a precise diet model; and generating an individualized diet intervention scheme, continuously collecting follow-up visit data, feeding back the follow-up visit data to the model, and dynamically updating model parameters. According to the invention, an accurate diet scheme with high individual suitability can be generated, the dynamic optimization capability is realized, and the diet intervention accuracy and long-term management effect of the patient with the inflammatory bowel disease are improved.
Owner:THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV

Kidney specific fasting-mimicking diet induces podocyte reprogramming and restores renal function in glomerulopathy

A low-salt fasting-mimicking diet (LS-FMD) is provided for promoting kidney regeneration and treating kidney disease. The LS-FMD comprises cyclic dietary interventions that reduce caloric and sodium intake to induce fasting-like metabolic effects while maintaining essential nutrition. In animal models of puromycin-induced nephrosis, LS-FMD cycles restore normal proteinuria levels and improve nephron structure and function relative to untreated controls. The diet activates kidney-specific gene expression programs and promotes a quiescent, non-proliferative state in mature podocytes, supporting renal recovery. In human subjects with chronic kidney disease, administration of fasting-mimicking diet cycles for five days per month over three months reduces proteinuria and improves endothelial function. The invention demonstrates that kidney-specific fasting-mimicking dietary cycles have therapeutic potential for slowing or reversing progressive renal disorders.
Owner:UNIV OF SOUTHERN CALIFORNIA +2

Nutrition enhancer containing kelp extract and preparation method thereof

The invention belongs to the technical field of nutrition fortifiers, and particularly relates to a nutrition fortifier containing kelp extract and a preparation method of the nutrition fortifier. The nutrition enhancer containing the kelp extract comprises the following components in parts by mass: 20-30 parts of the kelp extract, 50-60 parts of soybean protein powder, 5-15 parts of oat powder, 1-10 parts of inulin, 1-10 parts of sea cucumber powder and 1-5 parts of an undaria pinnatifida extract. The kelp extract is subjected to directional fermentation treatment by adopting a specific probiotic strain, so that the content and biological activity of fucoidin in the kelp extract are remarkably improved; meanwhile, a multi-level nutrition collaboration system is constructed; especially for chronic inflammatory diseases such as tumors, arthritis and psoriasis, the nutrition enhancer provides a safe and long-acting diet intervention scheme for specific people through anti-inflammatory and anti-angiogenesis dual-path effects, and has important clinical auxiliary application value.
Owner:FUJIAN RED SUN BOUTIQUE CO LTD

Application of Chinese yam active protein in preparation of medicine for regulating blood testis barrier to treat testis dysfunction

The invention relates to application of Chinese yam protein, in particular to application of Chinese yam active protein in preparation of medicine for regulating blood testis barrier to treat testis dysfunction. L-YP has unique fluorescence characteristics and remarkable antioxidant activity, and can effectively improve testis immune microenvironment disorder by repairing blood testis barriers and inhibiting NLRP3 and TLR4 / MyD88 / NF-kappa B inflammatory pathways. In combination with a molecular docking technology, a molecular mechanism that key components such as YP2 (mitochondrial ornithine aminotransferase) and the like realize immunoregulation through high-affinity binding is clarified for the first time. According to the application disclosed by the invention, a molecular docking technology is creatively combined with system experimental analysis, and a molecular mechanism of improving testis injury by the Chinese yam protein is illuminated from the perspective of a'structure-function-target 'synergistic effect, so that a novel dietary intervention strategy is provided for preventing reproductive toxicity caused by chemotherapy; the application potential of medicinal and edible components in the field of male reproductive health is highlighted.
Owner:CHANGCHUN UNIV OF CHINESE MEDICINE

Methods for treating or preventing prostate cancer

PCT designated stageWO2026102111A1Anhydride/acid/halide active ingredientsAntineoplastic agentsProstate Cancer PreventionOncology
The present invention relates, in part, to methods of treating or preventing prostate cancer in a subject in need thereof, wherein the method comprises combining dietary intervention with administration of at least one omega-3 fatty acid.
Owner:RGT UNIV OF CALIFORNIA +3

Lactobacillus plantarum DX7 as well as method for producing indole lactic acid and application thereof

The invention provides lactobacillus plantarum DX7, a method for producing indole lactic acid by the lactobacillus plantarum DX7 and application of the lactobacillus plantarum DX7, and relates to the technical field of food microorganisms, the lactobacillus plantarum DX7 is preserved in Guangdong Microbial Culture Collection Center on June 12, 2025, and the preservation number is GDMCC NO.66498. The lactobacillus plantarum DX7 has the advantages that under the stimulation of the deep-grain walnut endopleura polyphenol, the tryptophan metabolic pathway of the lactobacillus plantarum DX7 is obviously activated, and the tryptophan can be efficiently converted into the ILA; experimental results show that the ILA yield of the strain reaches 217.56 g / mL. In addition, the bacterial strain and the deep-grained walnut endopleura polyphenol are combined for intragastric administration of DSS-induced colitis mice, and the colitis symptom can be remarkably relieved. The invention not only provides a new strategy for efficient biological preparation of the functional component ILA, but also provides a basis and a potential solution for dietary intervention of inflammatory bowel diseases.
Owner:KUNMING UNIV OF SCI & TECH