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39 results about "Dietary interventions" patented technology

Momordica grosvenori instant coffee beverage for assisting in reducing uric acid and preparation method of momordica grosvenori instant coffee beverage

The invention discloses a siraitia grosvenorii instant coffee beverage assisting in reducing uric acid and a preparation method thereof, and belongs to the technical field of food based on the theory of homology of medicine and food. The coffee beverage is composed of instant coffee powder, a compound sweetening agent, coconut milk powder, milk powder and composite herbal powder in a specific proportion. The compound herbal powder is composed of poria cocos, peach kernels, dried tangerine or orange peel and momordica grosvenori which are selected from a medicinal and edible substance catalog. The herbal active ingredients and a coffee system are deeply fused by optimizing an extraction process, the dual regulation effects of inhibiting xanthine oxidase and promoting uric acid excretion are synergistically exerted, and the technical contradiction that common caffeine possibly affects uric acid excretion is effectively solved. The zebra fish in-vivo experiment proves that the level of uric acid can be remarkably reduced (Plt: 0.001), the improvement rate is as high as 17.63%, and a safe and effective daily diet intervention scheme is provided for people with hyperuricemia while the coffee flavor and convenience are provided.
Owner:GUANGXI ZHUANGYUAN PHARM TECH CO LTD

Method, medium and equipment for personalized diet recommendation of enteritis patient

The invention discloses a personalized diet recommendation method for enteritis patients, a medium and equipment. The method comprises the following steps: continuously collecting diet image data, physiological state time sequence data and subjective symptom feedback data; performing food material component deconstruction and cooking mode identification on the diet image through a convolutional neural network, and generating a structured diet vector; analyzing physiological state time sequence data by using a hidden Markov model, and constructing an individualized physiological rhythm map; establishing a symptom triggering condition probability matrix based on a multi-modal association mining algorithm; generating an exploratory diet scheme according to the real-time physiological state of the user and the conditional probability matrix; dynamically updating the conditional probability matrix through an online reinforcement learning mechanism; and finally, periodically outputting a personalized diet taboo list and a safety exploration list. According to the method, through the dynamic correlation analysis of fusing the time sequence physiological features and the dietary components, accurate matching of diet recommendation and individual intestinal tract state fluctuation is realized, and the individuation and adaptability of diet intervention are effectively improved.
Owner:FUJIAN UNIV OF TRADITIONAL CHINESE MEDICINE

Application of a branched-chain amino acid-restricted diet in the preparation of drugs for treating liver metastases of tumors

PendingCN122297558AInhibit transferGrowth inhibitionPancreas CancersTranscriptional expression
This invention discloses the application of a branched-chain amino acid (BCAA) restricted diet in the preparation of drugs for treating liver metastases of tumors. Through mouse model experiments, this invention found that restricting the intake of BCAAs (valine, isoleucine, and leucine) in the diet, or using the SCD1 inhibitor A939572, can significantly inhibit liver metastases of tumors, especially pancreatic cancer liver metastases. Experimental results show that a BCAA restricted diet or SCD1 inhibitor can reduce the number and volume of liver metastases and inhibit their growth. This invention also reveals its mechanism of action: BCAA restriction reduces the propionylation modification of SREBP1, downregulates the transcriptional expression of its target gene SCD1, and thus reduces lipid synthesis, thereby exerting an anti-tumor liver metastasis effect. This invention provides a novel dietary intervention strategy and drug target for the treatment of liver metastases of tumors.
Owner:AFFILIATED HOSPITAL OF JIANGSU UNIV

Compositions and methods for improvement and maintenance of weight loss

The present invention provides nutritional compositions for use in weight loss dietary interventions or in particular weight maintenance after dietary interventions, preferably after low calorie dietary interventions. The nutritional composition comprises one or more amino acids selected from the group consisting of proline, histidine, glycine and / or hydroxyproline, or a combination thereof, which can be used to assist in weight loss in obese subjects that are resistant to weight loss only by means of caloric limiting dietary intervention. In addition, the nutritional composition of the present invention may be used to help maintain the weight loss, particularly after dietary intervention.
Owner:SOCIETE DES PRODUITS NESTLE SA

Companion diagnostic method for use in the treatment of irritable bowel syndrome with dietary interventions or faecal microbiota transplant

The present invention provides a diagnostic method which may be used to determine the likelihood that a subject with Irritable Bowel Syndrome (IBS) will respond to treatment with an IBS intervention diet. In particular, the method may be used to predict, or determine the likelihood of, a positive response of the subject with IBS to treatment with an IBS intervention diet, especially to determine the likelihood that the dietary intervention may have a positive (i.e. beneficial) effect on the subject's GI tract, specifically the GI tract microbiota, or other symptoms or complications of IBS (e.g. reducing severity thereof). The method of the present invention is based on analysing the abundance of certain bacteria in GI tract samples, e.g. by nucleic acid analysis.
Owner:GENETIC ANALYSIS

Interaction method based on intelligent tableware system and intelligent tableware system

The invention relates to the field of intelligent tableware, in particular to an interaction method based on an intelligent tableware system and the intelligent tableware system. The intelligent tableware system comprises a display unit, at least one containing unit, a sensing unit and / or a communication unit, the sensing unit is used for collecting the bearing state of each containing unit, the communication unit is used for receiving the bearing state of each containing unit transmitted by a far end, and the display unit is used for displaying an interactive interface; the method comprises the steps of obtaining a dining mode selected by a user; calling a corresponding dining guide process according to the dining mode, the dining guide process comprising a plurality of dining process nodes having a preset sequence, and each dining process node corresponding to a different interactive interface; the bearing state of at least one containing unit is monitored in real time, the interaction interface of the current dining process node is updated according to the bearing state, and personalized and forward diet intervention is achieved.
Owner:CHONGQING MINGYUEHU INTELLIGENT TECH DEV CO LTD

Fermented tea with alcoholic liver injury protection function and preparation method thereof

The invention relates to the technical field of functional food processing, in particular to fermented tea with an alcoholic liver injury protection function and a preparation method of the fermented tea. The functional tea beverage is prepared by optimizing the fungus compatibility proportion, the fermentation condition and the subsequent blending process, and the method is provided for dietary intervention of alcoholic liver injury due to the regulation effect on hepatic cell oxidative stress and inflammatory factors. The preparation method comprises the following steps: mixing the lucid ganoderma, the phellinus igniarius, the grifola frondosa and pure water according to a weight ratio of 1: 30, carrying out water bath extraction at 90 DEG C for 2-4 hours, filtering, mixing extract liquids according to a ratio, and adjusting the pH value to 5.0-6.0; inoculating yeast into a YPD culture medium, culturing at 22-31 DEG C for 24-96 hours until the pH value is 5.0-6.5 to obtain a yeast liquid, inoculating the obtained yeast liquid into the extract liquid obtained in the step 1), fermenting at 28 DEG C for 72 hours, and adjusting the pH value to 5.5; and heating at 60-70 DEG C for 10-15 minutes to inactivate the yeast, filtering, and refrigerating and storing.
Owner:MICROBIOLOGY INST OF SHAANXI

Key marker combination for individualized diet intervention decision and application thereof

PendingCN122050710AMedical data miningNutrition controlOverweight obesityRespiratory quotient
The invention provides a key marker combination for individualized diet intervention decision and application thereof. Specifically, three clusters based on a respiratory quotient (RQ) are found according to metabolic index change conditions before and after meals of people with normal body weight and overweight / obese people. In addition, key biomarkers for distinguishing the three clusters are also found; a prediction model constructed by using the key biomarkers can accurately divide subjects into three RQ clusters, and can be used for predicting a weight loss intervention result, so that the prediction model can be used as a reference for providing an individualized diet or exercise intervention decision. A system constructed according to the key marker is high in sensitivity and accuracy, used indexes are easy to obtain, and the key marker has a good clinical application prospect.
Owner:SHANGHAI INST OF BIOLOGICAL SCI CHINESE ACAD OF SCI

Broken sugar dietary therapy formula based on zaocys dhumnade or cobra and preparation method

The invention discloses a broken sugar dietary therapy formula based on zaocys dhumnade or cobra and a preparation method, and relates to the technical field of health preservation. The method comprises the following steps: S1, raw material pretreatment: treating sandworms: taking 1.5 kg of dry sandworms, removing sandbags, washing, and baking at 170 DEG C for 4 hours for later use; 135kg of zaocys dhumnade meat and 60kg of chicken are taken, washed and diced; taking 35kg of soybeans and 20kg of hericium erinaceus, washing and soaking for 2 hours; 2 kg of ginseng and 2 kg of dendrobe are taken and washed; 25 kg of dried scallops are taken and washed; s2, performing boiling and performing filling; aluminum cans are filled with the soup bases through an automatic filling machine (258 g per can), and the aluminum cans are sealed immediately; and S4, outer packaging: putting the sterilized tank body and the self-heating bag into an outer bowl, sealing with a film, and boxing. According to the invention, through the setting of a sugar-breaking dietary therapy method, the problems that the existing sugar-breaking or diet intervention product focuses on nutrient control and lacks systematic collaborative design and scientific proportioning for functional components (such as medicinal and edible active components) are solved.
Owner:GUANGXI GUIXIAOSHE AGRICULTURAL SCIENCE & TECHNOLOGY DEVELOPMENT CO LTD

Method and system for health intervention of diet structure based on physical data of obese children

ActiveCN121331379BNutritionEmergency medicine
The present application relates to the technical field of data processing and strategy optimization, and particularly relates to a diet structure health intervention method and system based on physical data of obese children. The present application firstly acquires physical data and nutrition data and groups children; further acquires intervention synchronism of each physical data according to deviation characteristics of each physical data compared with corresponding preset physical standard and similarity of changes in time domain of deviation characteristics of all physical data; further adjusts the diet structure of the target child according to the difference in intervention synchronism of each physical data of the target child and the children in the same group at the current period, in combination with the difference between the nutrition data and the preset recommended diet structure. By analyzing the individualized differences in the physical angle and the diet intake angle of the children, the diet structure of the children is continuously adjusted, the diet intervention adaptability is improved, and the intervention effect is ensured.
Owner:QINGDAO HONGZHU BIOTECHNOLOGY CO LTD

Soda water beverage added with nattokinase as well as preparation method and application of soda water beverage

The invention provides a soda water beverage added with nattokinase and a preparation method and application thereof, the soda water beverage added with nattokinase has a pH value of 7.8-8.2 and a carbonation degree of 0.8-1.2 g / L, and contains nattokinase, and the activity of the nattokinase is greater than or equal to 10,000 FU / L. The soda water beverage added with the nattokinase is applied to preparation of products for regulating PCSK9 activity, reducing the low density lipoprotein cholesterol LDL-C level in blood or preventing / assisting in managing obesity and related metabolic syndromes. The product is a beverage, a health food or a dietary supplement. The nattokinase can be used for specifically hydrolyzing the Ser153-Gly154 site of the PCSK9 protein, and the Ser153-Gly154 site of the PCSK9 protein can be specifically hydrolyzed. According to the beverage, the activity of nattokinase is protected by optimizing pH and a carbonation system, the intestinal absorption rate of the nattokinase is improved, and the function of PCSK9 is inhibited in a targeted manner so as to regulate blood lipid metabolism. Compared with an existing oral enzyme preparation, the oral enzyme preparation has high efficiency, stability and consumption convenience, and an innovative diet intervention scheme is provided for obesity and related metabolic diseases.
Owner:AFFILIATED HOSPITAL OF JIANGSU UNIV

Lactobacillus plantarum dx7, method for producing indolelactic acid and use thereof

The application provides a lactobacillus plantarum DX7 and a method and application thereof for producing indole lactic acid, relates to the field of food microbial technology, and the lactobacillus plantarum DX7 has been preserved in the Guangdong Microbial Culture Collection Center on June 12, 2025, and the preservation number is GDMCC NO.66498. The lactobacillus plantarum DX7 in the application is significantly activated under the stimulation of deep-line walnut inner seed coat polyphenol, and can efficiently convert tryptophan into ILA. Experimental results show that the ILA yield of the strain reaches 217.56 mu g / mL. Moreover, the strain and deep-line walnut inner seed coat polyphenol can significantly relieve the colon inflammation symptoms of a DSS-induced colon inflammation mouse by gavage. The application not only provides a new strategy for efficient biological preparation of the functional component ILA, but also provides a basis and potential solution for dietary intervention of inflammatory bowel disease.
Owner:KUNMING UNIV OF SCI & TECH

A medicinal and edible therapeutic composition with the effects of clearing lung, resolving phlegm, removing blood stasis and dissolving nodules

PendingCN122376680AFormularyHouttuynia
This invention discloses a food-medicine composition with the effects of clearing the lungs, resolving phlegm, dispersing blood stasis, and eliminating nodules, belonging to the fields of functional food therapy and traditional Chinese medicine lung conditioning technology. This invention completely abandons the defects of traditional low-dose health care formulas. All raw materials are strictly formulated according to the legally prescribed therapeutic doses in the Chinese Pharmacopoeia and the conventional dosages in traditional Chinese medicine clinical prescriptions for pulmonary nodules. It uses high doses of Houttuynia cordata and fresh Imperata cylindrica root as the core heat-clearing and nodule-dispersing principal herbs, combined with sufficient amounts of Platycodon grandiflorus, Citrus reticulata peel, and Citrus reticulata peel to clear the lungs and resolve phlegm; a high proportion of Lilium brownii, Polygonatum odoratum, and Ophiopogon japonicus to nourish yin and protect the lungs; and Prunus persica to invigorate blood and disperse blood stasis, constructing a three-level pharmacopoeia-compliant dosage system. This invention features a rigorous formulation, a balanced combination of hot and cold properties of the medicinal ingredients, and sufficient potency. It breaks through the technical bottleneck of traditional dietary therapy formulas that cannot deeply disperse stagnation. It can effectively intervene in the phlegm and blood stasis in the lungs, improve pulmonary nodules, and eliminate long-term symptoms of lung heat and excessive phlegm, chest tightness, and dry throat. Its efficacy can be verified through multiple dimensions, including human trials, animal pharmacology experiments, and real clinical cases. The technology is innovative and practical, and it can be used as a high-end conditioning food for sub-healthy lungs in the general public, as well as a long-term standardized dietary intervention program for people with pulmonary nodules. It has extremely high value for industrialization and promotion.

Method and device for evaluating fetal distress risk based on saturated fatty acid intake and medium

The invention discloses a method and a device for evaluating fetal distress risk based on saturated fatty acid intake, and a medium. The method comprises the following steps: acquiring daily average saturated fatty acid intake data of a pregnant woman to be evaluated; comparing the intake with a plurality of preset risk threshold intervals, and determining a corresponding fetal distress risk level; and finally outputting an evaluation result containing the risk level. According to the method, objective dietary data and a rigorous statistical method are combined, and the association between saturated fatty acid and fetal distress is converted into a clear quantitative risk assessment standard, so that the progress of risk assessment from qualitative to quantitative and from fuzzy to accurate is realized; the problem that in the prior art, an individualized and quantitative fetal distress risk assessment tool for saturated fatty acid is lacked is solved. The invention provides a rapid, convenient and non-invasive risk screening tool, and provides a scientific basis for pregnancy diet intervention and clinical monitoring.
Owner:CHONGQING MEDICAL UNIVERSITY

Inflammatory bowel disease accurate diet intervention scheme generation method and system based on multi-modal data integration

The invention discloses an inflammatory bowel disease accurate diet intervention scheme generation method and system based on multi-modal data integration, and relates to the technical field of diet and health management. The method comprises the following steps: acquiring crowd health data from a plurality of data sets; analyzing and marking the acquired crowd health data; constructing an identification rule and consistency calibration model of the macroscopic phenotype combination features; constructing a biomics alignment data structure reflecting diet and lifestyle-clinical medication-disease outcome association; performing reliability weighting on the macroscopic phenotypic information of the individuals, and endowing each layer of data of different data sets with corresponding weights; constructing a multi-dimensional comprehensive data matrix; establishing a precise diet model; and generating an individualized diet intervention scheme, continuously collecting follow-up visit data, feeding back the follow-up visit data to the model, and dynamically updating model parameters. According to the invention, an accurate diet scheme with high individual suitability can be generated, the dynamic optimization capability is realized, and the diet intervention accuracy and long-term management effect of the patient with the inflammatory bowel disease are improved.
Owner:THE THIRD XIANGYA HOSPITAL OF CENT SOUTH UNIV

Kidney specific fasting-mimicking diet induces podocyte reprogramming and restores renal function in glomerulopathy

A low-salt fasting-mimicking diet (LS-FMD) is provided for promoting kidney regeneration and treating kidney disease. The LS-FMD comprises cyclic dietary interventions that reduce caloric and sodium intake to induce fasting-like metabolic effects while maintaining essential nutrition. In animal models of puromycin-induced nephrosis, LS-FMD cycles restore normal proteinuria levels and improve nephron structure and function relative to untreated controls. The diet activates kidney-specific gene expression programs and promotes a quiescent, non-proliferative state in mature podocytes, supporting renal recovery. In human subjects with chronic kidney disease, administration of fasting-mimicking diet cycles for five days per month over three months reduces proteinuria and improves endothelial function. The invention demonstrates that kidney-specific fasting-mimicking dietary cycles have therapeutic potential for slowing or reversing progressive renal disorders.
Owner:UNIV OF SOUTHERN CALIFORNIA +2

Nutrition enhancer containing kelp extract and preparation method thereof

The invention belongs to the technical field of nutrition fortifiers, and particularly relates to a nutrition fortifier containing kelp extract and a preparation method of the nutrition fortifier. The nutrition enhancer containing the kelp extract comprises the following components in parts by mass: 20-30 parts of the kelp extract, 50-60 parts of soybean protein powder, 5-15 parts of oat powder, 1-10 parts of inulin, 1-10 parts of sea cucumber powder and 1-5 parts of an undaria pinnatifida extract. The kelp extract is subjected to directional fermentation treatment by adopting a specific probiotic strain, so that the content and biological activity of fucoidin in the kelp extract are remarkably improved; meanwhile, a multi-level nutrition collaboration system is constructed; especially for chronic inflammatory diseases such as tumors, arthritis and psoriasis, the nutrition enhancer provides a safe and long-acting diet intervention scheme for specific people through anti-inflammatory and anti-angiogenesis dual-path effects, and has important clinical auxiliary application value.
Owner:FUJIAN RED SUN BOUTIQUE CO LTD

Application of Chinese yam active protein in preparation of medicine for regulating blood testis barrier to treat testis dysfunction

The invention relates to application of Chinese yam protein, in particular to application of Chinese yam active protein in preparation of medicine for regulating blood testis barrier to treat testis dysfunction. L-YP has unique fluorescence characteristics and remarkable antioxidant activity, and can effectively improve testis immune microenvironment disorder by repairing blood testis barriers and inhibiting NLRP3 and TLR4 / MyD88 / NF-kappa B inflammatory pathways. In combination with a molecular docking technology, a molecular mechanism that key components such as YP2 (mitochondrial ornithine aminotransferase) and the like realize immunoregulation through high-affinity binding is clarified for the first time. According to the application disclosed by the invention, a molecular docking technology is creatively combined with system experimental analysis, and a molecular mechanism of improving testis injury by the Chinese yam protein is illuminated from the perspective of a'structure-function-target 'synergistic effect, so that a novel dietary intervention strategy is provided for preventing reproductive toxicity caused by chemotherapy; the application potential of medicinal and edible components in the field of male reproductive health is highlighted.
Owner:CHANGCHUN UNIV OF CHINESE MEDICINE

Methods for treating or preventing prostate cancer

PCT designated stageWO2026102111A1Anhydride/acid/halide active ingredientsAntineoplastic agentsProstate Cancer PreventionOncology
The present invention relates, in part, to methods of treating or preventing prostate cancer in a subject in need thereof, wherein the method comprises combining dietary intervention with administration of at least one omega-3 fatty acid.
Owner:RGT UNIV OF CALIFORNIA +3

Diet structure health intervention method and system based on constitution data of obese children

The invention relates to the technical field of data processing and strategy optimization, in particular to a diet structure health intervention method and system based on constitution data of obese children. The method comprises the following steps: firstly, acquiring physique data and nutrition data and grouping children; further obtaining intervention synchronism of each item of physique data according to change similarity of deviation characteristics of each item of physique data relative to a corresponding preset physique standard and overall deviation characteristics of all items of physique data in a time domain; and further adjusting the dietary structure of the target child according to the difference of intervention synchronism of each item of physical data of the target child and the same group of children in the current period in combination with the difference of the ingested nutrition data and a preset recommended dietary structure. By analyzing the individualized difference between the physique angle and the diet intake angle of the child, the diet structure of the child is continuously adjusted, the diet intervention adaptability is improved, and the intervention effect is guaranteed.
Owner:QINGDAO HONGZHU BIOTECHNOLOGY CO LTD

Traditional Chinese medicine tongue appearance intelligent diagnosis model construction method, diagnosis system, device and storage medium

PendingCN122290952ADiagnostic systemTongue body
This invention discloses a method, system, device, and storage medium for constructing an intelligent diagnostic model for TCM tongue imagery, addressing the shortcomings of traditional tongue diagnosis, such as strong subjectivity, difficulty in quantification, and the crude feature extraction, weak integration with TCM theory, and lack of personalized intervention in existing AI systems. Through structured guidance, it achieves a closed-loop health management process encompassing tongue image collection, tongue coating localization, multi-dimensional feature extraction, constitution identification, and personalized dietary intervention. High-precision segmentation of the tongue and tongue coating, along with structured extraction of multi-dimensional tongue image features, enables high accuracy in constitution identification, generating personalized dietary recommendations and dynamic health management, thus improving the objectivity, repeatability, and clinical applicability of TCM tongue diagnosis. Users only need to take a picture of their tongue; the system outputs a complete analysis report within seconds, achieving "diagnosis upon tongue image capture." This is applicable to diverse scenarios such as home self-examination, community health monitoring, and remote TCM consultation, promoting the widespread adoption of TCM tongue diagnosis technology.
Owner:HENGDONG (BEIJING) TRADITIONAL CHINESE MEDICINE HOSPITAL (SOLE PROPRIETORSHIP)

A method for glycemic management of gestational diabetes based on a dietary inflammation index

PendingCN122369816AGlycemic managementIngested food
The application discloses a kind of based on diet inflammation index gestational diabetes mellitus blood sugar management method, comprising the following steps: S1: input pregnant woman information;Obtain the personalized information of pregnant woman, including: gestational age, pre-pregnancy / current weight, blood sugar risk level, dietary intake frequency, food intake, diet inflammation index initial score;S2: calculate diet inflammation index;Calculate nutrient intake, standardization processing, inflammation weight calculation, calculation;S3: predict blood sugar risk through blood sugar risk prediction module, output risk level;S4: generate diet program, three meals structure, food combination and heat distribution through individualized diet intervention module;S5: monitor blood sugar, adjust menu according to blood sugar change.Can combine carbohydrate and inflammation, establish diet inflammation blood sugar management new mode, realize accurate management.
Owner:CHONGQING MEDICAL UNIVERSITY

Clerodendrum trichotomum total flavone coffee composition with effects of resisting colorectal cancer and inhibiting tumor growth

The invention relates to the technical field of food biology, in particular to a coriandrum sativum total flavone coffee composition with the effects of resisting colorectal cancer and inhibiting tumor growth and application of the coriandrum sativum total flavone coffee composition. The total flavonoids coffee composition comprises the following components in parts by weight: 6 parts of total flavonoids of radix codonopsis and 12 parts of low-carbon coffee. Researches show that the composition can effectively inhibit proliferation, migration and invasion of colorectal cancer cells by down-regulating expression of lncRNA PTGES2-AS1, and plays a significant anti-tumor role. The coffee composition is based on natural active ingredients, has the advantages of synergistic interaction, high safety, small side effect and good palatability, can be prepared into functional food, solid beverage or health food, can also be used as a dietary auxiliary intervention product for colorectal cancer high-risk people, and can be used as a dietary auxiliary intervention product for colorectal cancer high-risk people. The traditional Chinese medicine composition is used for auxiliary prevention of tumors and nutrition supporting and conditioning during postoperative and radiotherapy and chemotherapy, and has a good application prospect.
Owner:YUNNAN PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Xod inhibiting peptides derived from sheep milk and methods of making and using the same

To address the problem that "existing XOD-inhibiting peptides are mostly derived from cow's milk or non-dairy proteins, and their peptide activity varies greatly, binding stability is limited, and mechanisms are unclear, thus restricting their application in the prevention and treatment of hyperuricemia and related metabolic diseases," this invention provides a group of XOD-inhibiting peptides derived from sheep milk, their preparation methods, and applications. The inhibiting peptides include the peptide sequences GPGGAW and FGER. In vitro enzyme activity assays show that the above peptides can effectively inhibit XOD activity and reduce uric acid production. The sheep milk-derived XOD-inhibiting peptides provided by this invention have the characteristics of clear origin, simple structure, and high safety, and can be used in functional foods, nutritional supplements, and dietary interventions, providing a novel active substance basis for the prevention and treatment of hyperuricemia and related metabolic diseases.
Owner:QILU NORMAL UNIV

Method and system for screening biomarkers of intestinal flora and metabolic products of overweight or obese patients for weight loss effect of dietary intervention, and application thereof

The present application relates to a method and system for screening biomarkers of gut flora and metabolic products of the effect of dietary intervention on weight loss of overweight or obese patients and application, belonging to the technical field of microbiome and related metabolome and human health. Based on the random controlled intervention test design, the biomarker combination is screened out as 6 kinds of bacteria and 3 kinds of fecal metabolites which are significantly related to weight loss effect, wherein the relative abundance of 6 kinds of bacteria and the concentration of 2 metabolites are negatively correlated with weight loss effect, and the concentration of 1 metabolite is positively correlated with weight loss effect. In addition, an efficient weight loss effect prediction model is established by using the screened biomarker combination, which provides a new strategy for realizing effective weight loss and helps to guide personalized weight management.
Owner:HUAZHONG UNIV OF SCI & TECH

Dynamic generation system for AI dietary scheme based on diabetic obese patient

The invention relates to the technical field of nutrition control, in particular to an AI diet scheme dynamic generation system based on diabetic obese patients, which comprises the following steps: acquiring the types of foods containing the same nutrient eaten by the patients in a regulation and control cycle, and acquiring the actual intake, preprandial blood sugar and postprandial blood sugar of different foods in each meal, the intake execution degree is determined according to the intake, the intake and the blood sugar change are combined to determine the blood sugar influence stability degree of the food, and the food compliance is determined according to the actual intake change and the intake difference index trend; determining the recommendation priority of each kind of food in combination with the food compliance, the blood sugar influence stability degree and the intake execution degree; and recommending and matching the foods with the same nutrients according to the recommendation priorities. On the premise that blood sugar control and nutrition balance are not affected, the acceptability of a patient to a dietary scheme can be enhanced, so that an effective dietary intervention effect is maintained under low compliance, and the applicability of the dietary scheme to the patient is improved.
Owner:RUIJIN HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE +1

Method and system for evaluating and intervening daily dietary nutrition of user

The invention relates to a method and system for evaluating and intervening daily dietary nutrition of a user, and the method comprises the steps: collecting diet video data of each meal of the user, and obtaining an image of eaten food from the diet video data; performing image processing on the image of the eaten food to obtain quantitative information of the food taken by the user; the food quantification information comprises a food type and a food intake volume; based on a preset calorie database and the food quantification information, calculating respective intake amounts of a plurality of monitoring indexes ingested by the user; and judging whether the intake of each monitoring index exceeds a corresponding preset threshold, and if the intake of any monitoring index is greater than or equal to the corresponding preset threshold, intervening the user based on a preset diet intervention scheme. According to the method, diet intervention suggestions fitting individual habits are output in real time under the condition that the data processing amount is small, and fine evaluation and intervention on daily diet of the user are achieved.
Owner:成都医学院第一附属医院

Rhodotorula mucilaginosa DM2025, microbial inoculum and preparation method and application thereof

The invention discloses a Rhodotorula mucilaginosa DM2025, a microbial agent and a preparation method and application thereof, and belongs to the technical field of microorganisms. The invention provides a Rhodotorula mucilaginosa DM2025, the preservation number is CGMCC No.35517, the in-vitro cholesterol reduction efficiency degradation rate of the Rhodotorula mucilaginosa DM2025 reaches 32.25 + / -2.54%, meanwhile, the Rhodotorula mucilaginosa DM2025 has the function of regulating lipid metabolism disorder in a multi-target manner, and in-vivo experiments prove that the Rhodotorula mucilaginosa DM2025 can reduce the serum TC and LDL-C levels of high-fat and high-cholesterol diet mice at the same time, and can be used for preparing high-fat the weight gain can be obviously inhibited, the epididymis fat index is reduced, the brown fat index is increased, and the fasting blood-glucose increase is obviously relieved; the strain is derived from the intestinal tract of a mammal, has no pathogenicity, does not produce toxin through strict aerobic culture, avoids the side effect risk of statins, and is suitable for long-term diet intervention; the compound can be applied to preparation of medicines for reducing cholesterol, blood fat and blood sugar and losing weight, and has important value in development of functional food or health care products.
Owner:DALIAN MEDICAL UNIVERSITY

Application of serofluid in preparation of medicine for preventing and treating polycystic ovarian syndrome

The invention discloses application of serofluid in preparation of a medicine for preventing and treating polycystic ovarian syndrome, and belongs to the technical field of biological medicine. According to the present invention, the traditional fermented delicious food slurry is adopted as the novel dietary therapy scheme for the intervention treatment of the polycystic ovarian syndrome (PCOS), the limitation of excessive dependence on the drug intervention in the existing treatment scheme is broken through, and the in vivo experiment reveals that the slurry can alleviate the PCOS rat ovarian dysfunction, improve the PCOS rat glucose and lipid metabolism disorder, and improve the PCOS rat ovarian dysfunction. According to the present invention, the traditional Chinese medicine composition has characteristics of low cost and pure natural property, can alleviate the PCOS rat inflammatory reaction, can avoid the liver and kidney burden of the PCOS traditional drug treatment and the side effect of the hormone drug, can meet the sustainable requirement of chronic disease management, can provide the scientific normal form for the fusion of the traditional dietary therapy intelligence and the modern medical requirement, and can promote the innovative development of the PCOS dietary intervention strategy.
Owner:NINGXIA MEDICAL UNIV

Diet intervention recommendation method based on reinforcement learning

The invention discloses a diet intervention recommendation method based on reinforcement learning, and the method comprises the following steps: collecting diet behavior data and health state data of a user, and constructing a behavior track matrix and a health feature set; constructing a compliance fatigue function based on the behavior track matrix, and generating a compliance fatigue score; constructing a shielding mapping vector, and determining a diet intervention action set based on a preset threshold rule; inputting the health feature set into an improved Dueling DQN model, and generating a state value and an action advantage value; performing weight correction on each action in the diet intervention action set; fusing the state values with the corrected action advantage values, constructing a state action value function Q value set of the diet intervention actions, and generating recommendation score distribution of the diet intervention actions; and selecting the diet intervention action with the highest score as a recommendation result. According to the invention, the behavior fatigue and health state change of the user can be dynamically perceived, and the individual adaptability and behavior compliance of diet recommendation are improved.
Owner:HEBEI SANYI INFORMATION TECHNOLOGY CO LTD