23 results about "Sucrose stearate" patented technology

The invention provides mint hydrogel for diminishing inflammation and relieving itching and a preparation method thereof. The hydrogel is prepared from 10 to 30 parts of herba menthae extract, 5 to 15 parts of melaleuca alternifolia leaf water, 15 to 25 parts of aloe vera gel, 8 to 15 parts of glycerol, 2 to 6 parts of essential oil compound, 1 to 4 parts of sweet-scented osmanthus extract, 1 to 5 parts of artemisia indica extract, 0.1 to 0.5 part of cross-linking agent, sucrose stearate, sorbic anhydride olivic acid, p-hydroxyacetophenone and the like. The essential oil compound is subjected to beta-cyclodextrin / sodium alginate double-embedding treatment, and the cross-linking agent is chitosan grafted hyaluronic acid. The preparation process comprises the steps of composite water phase preparation, essential oil activation, gradient mixing of extracts, cross-linking reaction, high-pressure homogenization, gradient photocuring and the like. Tests show that the maximum anti-inflammatory swelling inhibition rate of the hydrogel reaches 68.9%, the maximum itching relieving rate of the hydrogel reaches 80.6%, the anti-inflammatory and itching relieving effects can be effectively achieved, and the performance of the hydrogel is improved through the cooperation of all the raw materials and the technology.

The present invention provides an emulsified composition, a preparation method, and an application thereof. The emulsified composition comprises a polyol, a sucrose fatty acid ester, and a polyglycerol fatty acid ester; the sucrose fatty acid ester is a combination of sucrose laurate, sucrose dilaurate, sucrose palmitate, and sucrose stearate. The emulsified composition of the present invention has a smaller emulsified particle size than conventional emulsions after use in cosmetics, and a narrower particle size distribution range, creating a better skin feel and having higher kinetic stability. The smaller particle size helps effectively deliver active ingredients into the skin, making it a potential carrier for cosmetic ingredients, achieving optimal dispersion of active ingredients in specific skin layers, resulting in better efficacy. Furthermore, the smaller particle size allows for rapid penetration into the deep layers of the skin and pores, effectively rinsing away makeup and dirt.

The invention relates to the technical field of textile printing and dyeing, and particularly discloses a disperse dye as well as a preparation method and application thereof. The disperse dye provided by the invention comprises a disperse pigment and an auxiliary agent, the auxiliaries comprise ionic liquid containing imidazolyl, sodium gluconate and sucrose stearate. According to the invention, specific components of the auxiliary agent in the disperse dye are limited, and all the components have a synergistic effect, so that the structural stability of the disperse pigment in an alkali and hydrogen peroxide coexistence environment is obviously improved, and the dyeing uniformity and stability of the disperse dye on polyester-cotton knitted fabric can also be improved.

The invention discloses a ceramide transdermal enhanced transporter preparation as well as a method and application thereof, and belongs to the technical field of transdermal delivery preparations. The preparation comprises the following components in parts by mass: 5-15 parts of hydrogenated lecithin, 1-5 parts of ceramide, 2-8 parts of cholesterol, 1-3 parts of stearic acid, 0.5-5 parts of an edge activator, 20-50 parts of absolute ethyl alcohol and 100-200 parts of ultrapure water, and the edge activator is selected from one of sodium cholate, SP60 or sucrose stearate and has a specific concentration gradient. The preparation method comprises the steps of organic phase preparation, water phase pretreatment, mixed hydration and particle size adjustment. The edge activator is used for regulating and controlling a lipid bilayer structure, the deformation index of the preparation is remarkably increased, the problems that ceramide is poor in water solubility, prone to crystallization and low in transdermal efficiency are solved, the preparation is excellent in stability, the intradermal retention amount and the skin permeation amount are remarkably higher than those of traditional lipidosome, deep skin delivery of ceramide can be achieved, and the application prospect is wide. And the composition has no skin irritation and is suitable for preparing skin barrier repairing, moisturizing or anti-inflammatory external products.

The invention discloses a cleansing ointment and a preparation method thereof, the cleansing ointment comprises the following components in percentage by mass: 1-20% of a surfactant, the surfactant comprises polyglycerol-10 behenate / eicosane diacid ester, polyglycerol-2 stearate and glyceryl stearate, and the balance of water, or the composition comprises polyglycerol-10 behenate / eicosane diacid ester, PEG-7 glyceryl cocoate and sucrose stearate, or comprises polyglycerol-10 behenate / eicosane diacid ester; the polyhydric alcohol is one or more of butanediol, 1, 2-pentanediol, glycerol, dipropylene glycol, sorbitol and ethyoxyl diethylene glycol, and the polyhydric alcohol is one or more of 1, 2-pentanediol, 1, 2-pentanediol, glycerol, dipropylene glycol, sorbitol and ethyoxyl diethylene glycol; and 30-65% of grease. The cleansing ointment can improve the problems of oil outlet and layering, is good in stability, has a good moisturizing effect, has a more excellent moisturizing effect compared with a commercially available wax-based cleansing ointment, and can maintain a high skin moisture content for a period of time after cleansing.

The invention discloses a febuxostat solid dispersion tablet as well as a preparation method and application thereof. The tablet comprises a solid dispersion consisting of an active component febuxostat, sucrose stearate and pullulan, and pharmaceutic adjuvants. The preparation method comprises the following steps: preparing a solid dispersion from febuxostat, sucrose stearate and Pulullan by a hot melt extrusion method or a solvent method, crushing, sieving, mixing with other auxiliary materials, and tabletting to obtain the febuxostat tablet. According to the invention, sucrose stearate and pullulan are innovatively combined, and the sucrose stearate and pullulan have a remarkable synergistic effect in the aspects of inhibiting drug crystallization and stabilizing an amorphous state. The prepared tablet is excellent in dissolution performance, the bioavailability of the tablet is far higher than that of a reference preparation, more importantly, the tablet has excellent physical stability, medicine recrystallization in the storage process can be effectively prevented, and the technical problem that a traditional solid dispersion is poor in stability is solved. The method is mature in process and suitable for industrial production.

The application relates to the field of skin care products and discloses a ceramide liposome for skin care products and a preparation method thereof, the ceramide liposome comprising the following components in parts by weight: 5-10 parts of hydrogenated lecithin, 0.5-2 parts of modified cholesterols, 0.5-2 parts of ceramides, 0.1-2.5 parts of sucrose stearate, 0.1-1 part of polyglyceryl-10 stearate and 15-30 parts of an organic solvent; the modified cholesterols are prepared by grafting glycine cholesterols and carboxymethyl chitosan through chemical reactions, the glycine cholesterols are prepared by taking cholesterols, N-tert-butoxycarbonylglycine and trifluoroacetic acid as raw materials, and the carboxymethyl chitosan is prepared by grafting chloroacetic acid and chitosan; the ceramide liposome with good stability and good skin barrier repair and moisturizing and water-locking effects is prepared by taking the hydrogenated lecithin, the modified cholesterols, the ceramides, the sucrose stearate and the polyglyceryl-10 stearate as raw materials.

The application discloses a stable whitening oral composition based on bio-enzyme catalysis, and belongs to the technical field of oral care products. The stable whitening oral composition based on bio-enzyme catalysis is characterized in that the components in the formula mainly include a humectant, a polyethylene glycol, a peroxide, an abrasive, an acyl donor, a carboxyl esterase, a sweetener, a fragrance, an anionic surfactant, a fluoride, a compound emulsifier, a thickening agent, a phosphate and an amphoteric surfactant. The compound emulsifier is composed of sucrose palmitate and sucrose stearate. The paste of the composition has high centrifugal stability, high and low temperature storage stability and excellent extrusion performance. The carboxyl esterase has high catalytic activity, and can realize high-efficiency whitening effect under the condition of low-concentration hydrogen peroxide.

The invention provides a spray based on nano shea butter and a preparation method thereof, and belongs to the technical field of cosmetics, the spray based on nano shea butter comprises the following raw materials: 18-22 wt% of shea butter, 2-4 wt% of soya bean lecithin, 0.4-0.6 wt% of cholesterol, 0.4-0.6 wt% of tocopheryl acetate, 0.7-1.2 wt% of sucrose stearate, 0.1-0.2 wt% of a preservative, 4-6 wt% of 1, 3-propanediol, 1, 3-propanediol, 1, 3-propanediol and the balance of water. The skin care product is prepared from 1, 3-butanediol, 2 to 4 weight percent of glycerol, 0.2 to 0.4 weight percent of peptide, 1.5 to 3 weight percent of Chinese herbal medicine extract, 1 to 2 weight percent of vitamin C, 0.1 to 0.3 weight percent of hyaluronic acid, 0.04 to 0.06 weight percent of sodium phytate and the balance of water. The skin care spray prepared by the invention is good in stability, free of oil-water separation phenomenon, quick to absorb and free of sticky feeling, and has the effects of moisturizing, whitening and astringing.

The present application relates to a kind of novel anti-freezing anti-cracking hand cream, according to percentage by weight, including, water phase:55~65%, oil phase:28~38%, emulsification-stable system:3~6%, active repair phase:2~4%, buffer-preservation-fragrance:0.3~0.8%;Wherein, water phase includes, bamboo leaf oligosaccharide:5~10%, 1,3-propanediol:8~12%, erythritol:3~6%, purified water: remainder to water phase 100%;Oil phase includes, camellia seed oil:8~12%, mango seed fat:6~10%, coconut oil MCT:4~8%, phytosterol ester:2~4%, rice bran wax microparticle:2~4%;Emulsification-stable system includes, sucrose stearate:2~3.5%, hydrogenated lecithin:1.5~2.5%, sphingomonad fermenting polysaccharide:0.3~0.7%.The present application also relates to a kind of novel anti-freezing anti-cracking hand cream preparation process.The present application gives quantifiable systematic breakthrough to the current hand cream "thick heavy stuff, high temperature inactivation, low temperature failure, poor wash resistance, slow repair, non-environmental protection " six structural pain points: absorption is fast, extrusion force is small, wash resistance is prolonged, and fissured healing is fast.

The application discloses a stable whitening oral composition based on bio-enzyme catalysis, and belongs to the technical field of oral care products. The stable whitening oral composition based on bio-enzyme catalysis is characterized in that the components in the formula mainly include a humectant, a polyethylene glycol, a peroxide, an abrasive, an acyl donor, a carboxyl esterase, a sweetener, a fragrance, an anionic surfactant, a fluoride, a compound emulsifier, a thickening agent, a phosphate and an amphoteric surfactant. The compound emulsifier is composed of sucrose palmitate and sucrose stearate. The paste of the composition has high centrifugal stability, high and low temperature storage stability and excellent extrusion performance. The carboxyl esterase has high catalytic activity, and can realize high-efficiency whitening effect under the condition of low-concentration hydrogen peroxide.

The invention relates to the field of fruit and vegetable fresh keeping, and discloses preparation and application of a micro-emulsion containing basil essential oil, and the micro-emulsion containing basil essential oil comprises basil essential oil, a surfactant, a cosurfactant and water. The basil essential oil is selected as a natural bacteriostatic agent, polyethylene glycol 40 hydrogenated castor oil and sucrose stearate are compounded to serve as a surfactant, diethylene glycol monoethyl ether serves as a cosurfactant, and the microemulsion containing the basil essential oil is prepared through a dripping method. The prepared microemulsion containing basil essential oil is safe and reliable, is in an oil-in-water type, has a particle size of less than 100 nm, has good dispersibility, and has good centrifugal stability and storage stability. Meanwhile, the fresh-keeping carton is prepared from the micro-emulsion containing the basil essential oil, the shelf life of the grapes can be prolonged to 15 days or above when the grapes are stored at the room temperature, and a new technical scheme is provided for green and fresh-keeping packaging of fruits and fresh agricultural products.

According to the rivaroxaban-containing tablet and the preparation method thereof, specific auxiliary materials are screened out, the ratio of the auxiliary materials is controlled, a lactose microcrystalline cellulose co-treatment substance is used as a filling agent, a microcrystalline cellulose-sodium carboxymethyl cellulose compound is used as a dispersing agent, sucrose stearate is used as a wetting agent, and the rivaroxaban-containing tablet is prepared. The rivaroxaban tablet solves the problems of hygroscopicity, poor compressibility, stickiness, poor content uniformity, slow disintegration, poorer dissolution rate and the like of tablet materials, the whole tablet is simple in auxiliary materials and only comprises three auxiliary materials, in the preparation process of the tablet, a microcrystalline cellulose-sodium carboxymethyl cellulose compound, sucrose stearate, rivaroxaban and purified water are prepared into a suspension, and the suspension is added into the tablet to prepare the rivaroxaban tablet. According to the present invention, the prepared tablet has the advantages of smooth tablet surface, good compressibility, good content uniformity, rapid disintegration, rapid dissolution, good stability and the like, and the whole preparation method is simple, and is suitable for large-scale industrial production.

The invention relates to environment-friendly degradable composite leather and a preparation method thereof in the technical field of composite leather, the environment-friendly degradable composite leather comprises a waterproof coating, a synthetic leather surface layer, a bonding layer and a cloth base layer from top to bottom, the synthetic leather surface layer is formed by mixing, melting and extruding modified coffee grounds, a thermoplastic elastomer and a fusion agent; the modified coffee grounds are obtained by degreasing and drying ethyl alcohol, an amino silane coupling agent and sucrose stearate in sequence, the side, close to the synthetic leather surface layer, of the cloth base layer is compounded with the synthetic leather surface layer through a bonding layer, and the synthetic leather surface layer is located above the cloth base layer and is subjected to foaming treatment. According to the structure, sucrose stearate can be absorbed, original lipid substances of the coffee grounds are covered, and the situation that residual lipid substances of the coffee grounds after alkali washing are prone to mildewing is overcome.

The application discloses a kind of natural acne-removing soothing compositions and preparation method and application thereof, belong to daily chemical field.The composition comprises 1-3 parts of natural emulsifier, 2-5 parts of emulsifying aid, 0.1-0.8 parts of oil control antibacterial agent, 0.5-2 parts of composite essential oil, 0.1-0.8 parts of soothing agent and 1-2 parts of deionized water by weight;Wherein natural emulsifier is the mixture of sucrose stearate and polyglycerol-10 laurate, emulsifying aid is 1,3-propanediol, oil control antibacterial agent is one or compound of persicin and magnolia officinalis extract, composite essential oil is the mixture of wild chrysanthemum, lavender and orchid grass essential oil, soothing agent is the compound of stearyl glycyrrhizinate and asiaticoside extract.The application also discloses the preparation method of the composition, and the microemulsion prepared by the application is natural, mild, has excellent extreme environmental stability, has antibacterial and anti-inflammatory and soothing repair functions, has good transdermal absorption, can effectively improve acne, and is suitable for the preparation of functional skin care products.

The preparation method comprises the following steps: adding deionized water, pearl powder, a humectant, essence, gypenoside, caprolactam-based silicone oil, trehalose, propylene glycol, nicotinic acid amine and sucrose stearate into a stirring device, and stirring to obtain a mixed solution, namely the whitening and moisturizing essence. Then adding a thickening agent while stirring, spraying the thickening agent into the mixed solution to fully dissolve the thickening agent, introducing the dissolved mixed solution into a filtering device through a feeding pipe, enabling the mixed solution to fall onto a filter screen, enabling the mixed solution filtered by the filter screen to flow out through a flow guide hole, enabling the mixed solution flowing out to enter a reaction kettle through a flow guide pipe, and continuously reacting to obtain a solution; and adding the perfume rose extract, the preservative and the vitamin E into the solution in the step 2, and stirring to obtain the essence with the whitening and moisturizing functions.

The invention discloses nimodipine injection and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. The nimodipine injection comprises nimodipine, sucrose stearate, propylene glycol, vitamin E TPGS, a histidine buffer solution, mannitol and water for injection. Stable micelles are formed by sucrose stearate and vitamin E TPGS, the histidine buffer solution inhibits oxidative degradation, and the mannitol regulates osmotic pressure, so that the solubility and stability of the medicine are synergistically improved. The preparation method comprises the steps of buffer solution preparation, main medicine solution mixing, filtering and sterilization and the like. The injection provided by the invention is clear and transparent in accelerated test and long-term storage, the total impurity content is less than or equal to 0.28%, and no crystal is separated out; safety tests show that hemolysis and anaphylaxis are avoided, and irritation to blood vessels and muscles is low.

The invention belongs to the technical direction of cosmetics, and relates to a water-soluble transparent ceramide composition as well as a preparation method and an application method thereof. The ceramide composition is prepared from ceramide, a solubilizer, a solvent and water, wherein the solubilizer is prepared from at least two of sucrose stearate, sucrose laurate, PEG-40 hydrogenated castor oil, PPG-26-butanol polyether-26, polyglycerol-6 octoate, poloxamer 184 and PEG-60 hydrogenated castor oil; the solvent is prepared from at least two of glycerol, butanediol, methylpropanediol, 1, 3-propylene glycol, 1, 2-pentanediol, dipropylene glycol, isosorbide dimethyl ether, diethoxy diethylene glycol and succinic acid diethoxy ethyl ester; the solvent is prepared from at least two of glycerol, butanediol, methylpropanediol, 1, 3-propylene glycol, 1, 2-pentanediol, dipropylene glycol, isosorbide dimethyl ether, diethoxy diethylene glycol and succinic acid diethoxy ethyl ester; the ceramide composition prepared according to the matching of the raw materials is water-soluble, colorless and transparent, also has excellent moisturizing performance, is good in skin delivery effect, and has a relatively good application prospect.

The application provides osmanthus fragrans plant extract mosquito repellent spray with long-acting mosquito repellent and itching, swelling relieving effects and a preparation method thereof, and relates to the technical field of mosquito repellent products. The raw materials of the mosquito repellent spray are as follows: osmanthus fragrans flower extract 7-9 parts, melaleuca alternifolia leaf extract 8-11 parts, chrysanthemum artemisia extract 1-2 parts, radix morindae officinalis extract 12-16 parts, platycodon grandiflorum root powder 16-19 parts, plant essential oil 20-24 parts, glycerol 18-23 parts, sucrose stearate 6-9 parts, p-hydroxyacetophenone 0.2-0.5 parts, stabilizer 3-5 parts and peppermint water 110-120 parts. The mosquito repellent spray can interfere with the activities of mosquitoes to achieve a good mosquito repellent effect, and can form a uniform and stable protective film on the skin surface to prolong the mosquito repellent effect, and can also play a good soothing and skin converging role, reduce local inflammatory reactions, promote skin barrier repair, and effectively relieve itching, swelling and other discomforts caused by mosquito bites.

The present invention discloses an environmentally friendly anti-corrosion coating for the inner wall of a water-based aerosol can and a preparation method thereof, relating to the technical field of aerosol cans, wherein the environmentally friendly anti-corrosion coating contains quantum dots and bismuth oxide; the mass fraction of quantum dots in the environmentally friendly anti-corrosion coating is 7-8%; the mass fraction of bismuth oxide in the environmentally friendly anti-corrosion coating is 0.2-0.4%; the environmentally friendly anti-corrosion coating also includes: epoxy resin, diluent, toughening agent, sucrose stearate, defoaming agent, coupling agent, leveling agent, curing agent; the environmentally friendly anti-corrosion coating prepared by the present invention is mainly used for spraying on the inner wall of a water-based aerosol can to form a stable corrosion-resistant coating, thereby effectively avoiding the corrosive effect of the water-based aerosol medium on the aerosol can body. By spraying the environmentally friendly anti-corrosion coating of the present invention on the inner wall of the water-based aerosol can, a coating with high hardness and corrosion resistance can be formed, which can protect the surface of the aerosol can body from being eroded by the medium.

The invention relates to a fermentation composition containing liquorice, oat and orange peel as well as a preparation method and application of the fermentation composition. The composition comprises an oil phase component (containing squalane, cetostearyl alcohol, beeswax, magnesium stearate, polyglycerol-3-methyl grape distearate, sucrose stearate, ceramide NP and tocopherol) and a water phase component (containing a multi-bacteria symbiotic fermentation filtrate and deionized water, the filtrate is prepared from glycyrrhiza glabra, oat kernels and orange peel as raw materials, and the water phase component is prepared by mixing the glycyrrhiza glabra, the oat kernels and the orange peel. And carrying out symbiotic fermentation on plant lactobacillus, saccharomyces cerevisiae and aspergillus niger). Through a rubbing demulsification mechanism, a double-layer structure of'anti-oxidation and water locking of an oil phase outer layer and continuous slow release of a water phase inner layer 'is formed, so that the oxidation loss after the active matter is smeared is effectively reduced, and the transdermal efficiency and the efficacy durability are improved. The composition does not contain chemical stimulation components such as glucocorticoid in the whole process, is high in safety and is suitable for daily nursing of sensitive skin and allergy repair. The preparation method is simple and efficient, and the technical problem that the natural extract is easy to oxidize and inactivate after being smeared is solved.

The invention discloses a natural acne-removing soothing composition as well as a preparation method and application thereof, and belongs to the field of daily chemical products. The composition comprises the following components in parts by weight: 1-3 parts of a natural emulsifier, 2-5 parts of an emulsifying aid, 0.1-0.8 part of an oil-control antibacterial agent, 0.5-2 parts of compound essential oil, 0.1-0.8 part of a soothing agent and 1-2 parts of deionized water, wherein the natural emulsifier is a mixture of sucrose stearate and polyglycerol-10 laurate, the emulsifying aid is 1, 3-propylene glycol, the oil-control antibacterial agent is one or a compound of totarol and a cortex magnoliae officinalis extract, and the compound essential oil is a mixture of wild chrysanthemum essential oil, lavender essential oil and vetiver essential oil. The soothing agent is a compound of stearyl glycyrrhetinate and a centella asiatica extract. The invention further discloses a preparation method of the composition, and the prepared microemulsion is natural, mild, low in irritation, excellent in extreme environment stability, good in transdermal absorption, capable of effectively improving acnes and suitable for preparation of functional skin care products, and has antibacterial, anti-inflammatory, soothing and repairing effects.

This invention relates to the field of ophthalmic formulation technology, specifically disclosing a long-lasting moisturizing contact lens lubricant and its preparation method. The lubricant comprises an oil phase component consisting of active liquid paraffin, a ceramide analog, and phytosterol polyoxyethylene ether-20; an aqueous phase component consisting of an osmotic pressure regulator and purified water; and a cationic agent and a composite surfactant dispersed at the interface. The composite surfactant is composed of polysorbate 80 and sucrose stearate, and the dosage form is an oil-in-water nanoemulsion. Its preparation involves phase preparation, emulsification homogenization and interface control, stabilization treatment, and aseptic molding steps. The product exhibits good ocular compatibility, long-lasting moisturizing properties, and a stable emulsion system, significantly improving the comfort of contact lens wear.