39results about How to "Impaired inhibition" patented technology

The invention discloses a stool sample preservation liquid, a preparation method and application thereof. Specifically, the stool sample preservation liquid contains: 45 vol%-60 vol% of a fixing agent; 0.1 mass%-15 mass% of a fixing agent adjuvant; 0.01 mass%-1.5 mass% of an anticoagulant; 10 vol%-15 vol% of a buffer solution; 0.01 mass%-1 mass% of an ionic strength maintenance agent; 0.01 vol%-0.5 vol% of a nonionic detergent; and the balance water. The stool sample preservation liquid provided by the invention has the characteristics of easy preparation and low cost, can preserve stool samples at room temperature, also can effectively inhibit DNA degradation and cell damage of stool samples, maintain cell shape, and can preserve samples for a long time, and the preserved samples have high qualification rate during reutilization.

The invention provides a feces preservation solution, a preparation method and an application thereof and a feces preservation method, and belongs to the technical field of biological agents. The feces preservation solution is prepared from the following components: a chelating agent with concentration of 10-500 mmol / L, a bacteriostat with concentration of 100-600 mL / L, an ionic strength maintainer with concentration of 1-10 g / L and a denaturant with concentration of 1-50 g / L. The feces preservation solution can preserve feces samples at normal temperature, and can effectively inhibit DNA degradation and cell damage in feces samples and maintain cell morphology, and has better effect of inhibiting activity of degrading enzyme and microorganisms, and preservation time of the samples is long.

The present invention relates to kind one ginsenoside Rg2 preparing process suitable for industrial production, and gradient salt separation process with simple operation is used in substituting traditional silicon gel chromatography process. The present invention also relates to medicine composition with ginsenoside Rg2 as active component and its application in medicine for preventing and treating dementia, depression, peripheral circulation disturbance and related diseases.

The invention relates to a refrigerator with shelf lighting comprising a refrigerator main body having a storage room, at least one shelf provided inside of the storage room, a light source provided at a rear end of the shelf, a power supply provided at a rear of the storage room, the power supply supplying power to the light source, and a light guide plate provided at the at least one shelf. The light guide plate may guide light of the light source to a front of the shelf. Accordingly, it is possible to reduce a length of an electric wire connecting the light source to the power supply and prevent the occurrence of glare caused by direct lighting.

To provide a substrate for mounting a light-emitting device, which is provided with a silver reflection layer having a high reflectance and being less susceptible to deterioration of the reflectance due to corrosion and which has an improved light extraction efficiency. A substrate for mounting a light-emitting element (1), which comprises a substrate main body (2), a silver reflection layer (6) composed mainly of silver or a silver alloy, formed on the substrate main body (2), and a protective layer formed so as to cover the entire surface of the silver reflection layer (6), wherein the protective layer (7) contains an alumina filler and further contains a glass constituting the protective layer (7), having silver ions diffused therein. The concentration of silver ions contained in the glass of the protective layer (7) is at least 0.5 mass% and at most 5.0 mass%.

The invention aims to provide an excrement preserving fluid which is applied to excrement preservation. The excrement preserving fluid can preserve an excrement sample for a long time at normal temperature, can effectively inhibit DNA degradation and cell damage in the excrement sample, maintains cell morphology, and has a good inhibiting effect on the activity of degradation enzymes and microbes.The invention also provides a preparation method of the excrement preserving fluid. The excrement preserving fluid prepared by the preparation method is used for preserving excrement. The excrement preserving fluid comprises 10-500 mmol / L of a chelating agent, 1-100 g / L of a bacteriostatic agent, 1-10 g / L of an ionic strength maintaining agent, 1-50% (v / v) of a cell protective agent and 1-50 g / Lof a denaturing agent.

[problem]To provide a bearing device for a wheel, in which contradictory problems of reduction in weight and size and increased rigidity of the device are simultaneously solved and, in addition, scratches on balls during assembly are prevented from occurring to achieve improvement of acoustic characteristics and the life of the bearing. [MEANS FOR SOLVING THE PROBLEMS] The bearing device for a wheel has a hub wheel (4) integrally having a wheel mounting flange (6) and also having an inner rolling surface (4a) formed on its outer periphery. The pitch circle diameter PCDo of an outer ball (3) group of double-row ball (3, 3) groups is set larger than the pitch circle diameter PCDi of the inner ball (3) group thereof. The diameters of the balls (3) are set equal to each other. The number of the balls of the outer ball (3) group is set larger than the number of the balls of the inner ball (3) group. Corners (A to C) of the outer peripheral surface of the hub wheel (4) are crushed into a smooth circular arc shape. By this construction, occurrences of scratches on the balls during assembly are suppressed to improve acoustic characteristics of the bearing and also the rigidity of the device is enhanced and the life of the bearing is extended.

The invention belongs to the technical field of medicines and particularly relates to a pharmaceutical composition. The pharmaceutical composition contains fasudil hydrochloride and nucleotide derivatives, wherein the content of the nucleotide derivatives in the pharmaceutical composition is 0.1-25 times of the content of the fasudil hydrochloride. The invention also discloses a preparation method and application of the pharmaceutical composition. The pharmaceutical composition has the effects of improving the activity of myosin light chain phosphatase to expand blood vessels, reducing the tensions of endothelial cells, improving microcirculation of brain tissues, protecting nerve to avoid apoptosis and promoting nerve regeneration so as to prevent and reduce cerebral vasospasm caused by various reasons and selectively expand the spasmodic blood vessels; and the pharmaceutical composition can also be used for inhibiting the damage of cerebral neurons, promoting the axon growth of neural cells and relieving the inflammatory response of involved brain cells.

It is provided a support structure for a cooling unit for a vehicle, in which in one straight side edge portion of a rectangular cooling unit, a first support point and a second support point, which are set to be away from each other in a longitudinal direction of the one side edge portion, are supported by a first retention portion and a second retention portion, respectively, the first retention portion and the second retention portion being provided in a single support bracket fixed integrally to a vehicle body, the second retention portion supporting the second support point through a fragile portion that is broken to permit the second support point to be separated from the second retention portion when an external force equal to or larger than a predetermined value is applied to the second support point in a direction toward a rear side of a vehicle; and when the fragile portion is broken, the second support point being permitted to move toward the rear side of the vehicle, and to pivot in a direction of an arc with a center at the first support point.

Provided a port member for an infusion solution bag that is capable of suppressing occurrence of gaps or wrinkles in a sealed portion in a manufacturing process, and preventing damages to resin sheets of a bag body during storage or transportation. A port member for an infusion solution bag includes a tubular body portion having one end sealed by a plug member structured to enable a hollow needle to be pierced into the plug member, and a tubular to-be-sealed portion continuously formed with an other end of the body portion and having an inner space communicated with the inside of the body portion, the to-be-sealed portion being held between and sealed to end portions of resin sheets overlapped together to form a bag body having an inner space for accommodation of at least a medicine, in which the to-be-sealed portion thus sealed has a radially flattened shape.

Provided are a polarizing plate and an optical display device comprising the same, wherein the polarizing plate has a polarizing film, a first adhesive layer, a first optical compensation layer, a second adhesive layer, and a second optical compensation layer laminated successively, and elastic modulus measured by a micro-indenter at 25 DEG C on the surface of the second optical compensation layerwith regard to the polarizing plate is about 100MPa to about 1000MPa.

A form cutting tool (10a) is provided with a tool body (14) and a tooth section (15) formed on a circumferential portion near the tip of the leading end shaft section (17) of the tool body (14). An oiling passage (23), of which the opening at one end in the axial direction opens onto a flat surface (18) that is the leading end face of the leading end shaft section (17), is formed in the tool body (14). During cutting, cutting oil is supplied from the opening at the one end of the oiling passage (23) in the axial direction. As a result, it is possible to limit the occurrence of damage such as deposits or abrasion on the leading edge of the tooth section (15) and discharge of chips generated during machining to the outside of a circular member is facilitated.

The present invention provides an etching solution composition for a silver-containing metal film, which comprises nitric acid, polysulfonic acid, organic acid and water. The etching solution composition according to the present invention contains nitric acid, polysulfonic acid, organic acid, and water, and for a silver (Ag) or silver alloy metal film used as a reflector or wiring of a display device, damage to the lower film is suppressed, and during formation of fine wirings, it is possible to minimize the occurrence of undesirable deviations and debris or precipitates, and can exhibit excellent etching characteristics.

Provided is a reinforcing and repairing method for a Dougong of a historic building. If the tenon of the Dougong is cracked, twisted or rotten, the cracked, twisted or rotten portion of the tenon can be removed firstly, then, a piece of dry hardwood is used for manufacturing the removed part according to the type and the size of the original tenon, the length of a newly-manufactured part should be larger than that of the original tenon by once to twice, dovetail joints are formed in the two ends of the hardwood so that the head of the Dougong can be connected with the hardwood through the dovetail joints, a groove is formed in the vertical face where the head of the Dougong is combined with the hardwood so that a silver ingot tenon can be embedded in the groove, the outer surface of the silver ingot tenon is made to be flush with the surface of the Dougong, the hardwood can be fixed to the head of the Dougong through the silver ingot tenon, and the bending resistance and the twisting resistance of the Dougong body can be improved. The joint of the Dougong body is made to be flat through caulking of putty, and then the surface of the Dougong is painted with wood oil.

The invention relates to a method for feeding a gas to a metallurgical vessel, the gas carrying a component in the gaseous and / or liquid state that can be condensed or evaporated. The gas is fed to the metallurgical vessel via one or more gas feeding devices. The gas speed is continuously increased in a first section in a number of gas feeding devices, and the gas is intimately mixed in a vortex zone with the components that can be condensed or evaporated. The gas speed is substantially maintained constant in a discharge section and the gas that is intimately mixed with the component carried along is blown into the metallurgical vessel. The invention also relates to a gas feeding device for carrying out the inventive method. The inventive method and the inventive gas feeding device allow prevention and / or reduction of nozzle damages.

The invention discloses an electrolyte solution for a high-voltage lithium-ion battery, comprising a non-aqueous organic solvent, a lithium salt and an additive, wherein the additive comprises vinylene carbonate and bis(trifluoromethylsulfonyl)imide A mixture prepared from lithium and benzonitrile; vinylene carbonate accounts for 1 to 10% by mass of the electrolyte, and the mixture accounts for 1 to 20% by mass of the electrolyte; wherein, in the mixture, bis(trifluoromethylsulfonyl ) The mass ratio of lithium imide and benzonitrile is 3:1. The invention is used in lithium-ion batteries, and can form a stable solid electrolyte interface film on the surface of the positive electrode and negative electrode materials of the high-voltage lithium-ion battery, effectively protect the stability of the positive and negative electrode materials in the cycle process, and further greatly improve the performance of the lithium-ion battery. High energy density, effectively improving the high temperature performance of lithium-ion batteries.

The invention relates to an internal combustion engine, comprising a fuel tank (36), a tank ventilation line (38) and a Venturi nozzle (30) arranged in a fluid-conducting component (16), the fluid-conducting component (16) and / or the Venturi nozzle (30) have / has an inflow channel (28), an access point (40) connected downstream of the inflow channel (28) and fluidically connected to the tank ventilation line (38), and an outflow channel (32) connected downstream of the access point (40). In this case, an outflow section (48) of the Venturi nozzle (30) downstream of the inlet point (40) is surrounded by a component (16) in such a way that a detection chamber (46) is formed around the outflow section (48), the detection chamber (46) having at least one inflow opening (50) via which the detection chamber (46) can be pressurized, the at least one pressure sensor (76, 84) is arranged and designed to detect a pressure that varies in the tank ventilation line (38) as a result of a leak in the detection chamber (46). The invention further relates to a method according to claim 9 for determining leaks on a fluid-conducting component (16) of such an internal combustion engine (10).

The invention relates to fumigating ointment for treating leucoderma and a preparation method, belonging to the technical field of Chinese traditional medicines. The fumigating ointment comprises guiding fumigating ointment prepared from the raw materials of Fruit of Chinese Holly and leaves of common fig, and main fumigating ointment prepared from the raw materials safflower, Chinese Angelica, stiff silkworm, malaytea acurfpea fruit, south dodder seed, puncturevine caltrop fruit, bighead atractylodes rhizome, calculus bovis artifactus and liquorice. In the invention, the fumigating ointment with special effects on soothing the liver, regulating qi, dispelling pathogenic wind, tonifying the liver and the kidneys, and radically curing various leucoderma is developed through multiple years of experiments according to modern Chinese medicine and traditional pharmacopeia by combining 'Prescriptions for Fifty-Two Diseases', which is derived from the Mawangdui Tomb of Han dynasty and relates to treatment on diseases through steam fumigation by decocted hot traditional Chinese medicines, and abiding by the dialectical treatment application principles of treating inside diseases externally, applying oral medicines externally and externally fumigating for treating inside of ancient prescriptions.

The invention provides a health-care product and a preparing method thereof, and belongs to the field of health-care products. The raw materials of the health-care product comprise, by weight, 5-50 parts of South Africa leaves and 5-50 parts of setaria viridis. The preparing method of the health-care product comprises the steps of rinsing of the materials, sterilizing the materials and mixing the materials after pulverizing the materials. The South Africa leaves are adopted as the main ingredient of the health-care product, then the South Africa leaves are matched with the setaria viridis, the South Africa leaves can protect the liver, cool the blood and purify the blood, and thus the South Africa leaves can improve blood supply in the liver, while the setaria viridis can remove heat from the liver and alleviate the burden of the liver, combining the effects of removing heat from the liver and nourishing the liver, the setaria viridis has an obvious effect of treating astigmatism, presbyopia, myopia, and glaucoma. According to the preparing method of the health-care product, through the operation of rinsing, sterilizing and the like, the effects of the raw materials of the health-care product are maintained to the largest extent, and the health-care product has more obvious effects of protecting vision, and protecting and clearing the liver.

The invention relates to a thermostat mixing valve for sanitary installations, with an axially displaceable top piece incorporating a cone by means of a rotatably mounted stem and a bushing with windows for hot and cold water entry, through A spring-loaded slider can be moved axially in the penetration sleeve, the slider is connected to a thermocouple with an adjusting piston, wherein the entry of hot and cold water through the window can be adjusted according to the movement of the slider, wherein the cone The body (5) comprises a bushing (51) which is closed by the bottom on its underside facing away from the mandrel (2) and in which a conical piston (53) is axially displaceable, The conical piston is preloaded towards the bottom by a spring (54). In the bottom there is a connecting channel axially aligned with the conical piston (53), which is simultaneously axially aligned with the regulating piston (81) of the thermocouple, and the conical piston (53) and / or thermocouple The adjusting piston (81) of the couple (8) can move into this connecting channel, and on the high position (hot water position) of the slider (7), the adjusting piston (81) abuts against the conical piston (53) and the bottom is in contact with the slider The block (7) is spaced, while in the low position (cold water position) of the slide (7) the adjusting piston (81) is spaced from the conical piston (53) and the bottom abuts against the slide (7).

The invention discloses octapeptide and application thereof in preparation of a medicine and a health-care product for improving memory. The amino acid sequence of the polypeptide is as follows: Trp-Cys-Pro-Phe-Ser-Arg-Ser-Phe (WCPFSRSF). The octapeptide provided by the invention can eliminate sleep deprivation induced mouse dysmnesia, and can significantly inhibit the excitatory toxicity and the oxidative stress of nerve cells. The polypeptide disclosed by the invention can be independently applied to health-care products for improving the memory, also can be compounded with other active ingredients capable of improving the memory and also can be prepared into microcapsules to improve the gastrointestinal digestion stability, the bioavailability and the shelf life of the polypeptide, and therefore, the polypeptide can be more favorably applied to the food industry and the field of health-care products.

Provided is an airbag device capable of suppressing direct contact between a corner of a folded part of a cover formed during unfolding of an airbag and the airbag. The cover is provided with: a tearing line (842); a cover unfolding part which is divided by the tearing line (842) and is unfolded during expansion of the airbag; and folding parts (882, 884) which are formed by at least part of the tearing line and are adjacent to the cover unfolding part. The corner is formed on the folding parts (882, 884). On a packaging material (35), a predetermined broken line (352) which is broken during the expansion of the airbag (32) is formed, and the packaging material (35) consists of at least one opening sheet (359) formed by the predetermined broken line (352). At least part of the opening sheet (359) is clamped between the airbag (32) and the corner during expansion of the airbag (32).

An excrement preserving fluid provided by the invention comprises trihydroxymethyl aminomethane, ethylenediamine tetraacetic acid, sodium chloride, polyethylene glycol octylphenol ether, ethanol and the balance of deionized water, and the excrement preserving fluid provided by the invention has different action reagents, can effectively protect human body exfoliated cells in excrement, prevents the exfoliated cells from being further degraded, the next step of detection aiming at the cast-off cells can be conveniently carried out; and exfoliated cells in the excrement sample can be effectively preserved, the sample can be preserved at normal temperature for a long time, cell damage, nucleic acid degradation and microbial activity in the sample can be effectively inhibited, and subsequent detection is not influenced. In addition, the invention further provides a preparation method and application of the excrement preserving fluid.

The present invention relates to kind one ginsenoside Rg2 preparing process suitable for industrial production, and gradient salt separation process with simple operation is used in substituting traditional silicon gel chromatography process. The present invention also relates to medicine composition with ginsenoside Rg2 as active component and its application in medicine for preventing and treating dementia, depression, peripheral circulation disturbance and related diseases.

The invention relates to fumigating ointment for treating leucoderma and a preparation method, belonging to the technical field of Chinese traditional medicines. The fumigating ointment comprises guiding fumigating ointment prepared from the raw materials of Fruit of Chinese Holly and leaves of common fig, and main fumigating ointment prepared from the raw materials safflower, Chinese Angelica, stiff silkworm, malaytea acurfpea fruit, south dodder seed, puncturevine caltrop fruit, bighead atractylodes rhizome, calculus bovis artifactus and liquorice. In the invention, the fumigating ointment with special effects on soothing the liver, regulating qi, dispelling pathogenic wind, tonifying the liver and the kidneys, and radically curing various leucoderma is developed through multiple years of experiments according to modern Chinese medicine and traditional pharmacopeia by combining 'Prescriptions for Fifty-Two Diseases', which is derived from the Mawangdui Tomb of Han dynasty and relates to treatment on diseases through steam fumigation by decocted hot traditional Chinese medicines, and abiding by the dialectical treatment application principles of treating inside diseases externally, applying oral medicines externally and externally fumigating for treating inside of ancient prescriptions.

The invention discloses an octapeptide and its application in preparing medicines for improving memory. The amino acid sequence of the polypeptide is: Trp-Cys-Pro-Phe-Ser-Arg-Ser-Phe (WCPFSRSF). The octapeptide of the invention can improve the memory impairment of mice induced by sleep deprivation, and can significantly inhibit the excitotoxicity and oxidative stress of nerve cells. The polypeptide of the present invention can be used alone as a drug for improving memory, or can be used in combination with other active ingredients that can improve memory, and can also be prepared into microcapsules to improve the digestive stability and bioavailability of the polypeptide in the gastrointestinal tract. And shelf life, so as to be better applied to the field of medicine.

The present invention relates to a refrigerator with an illuminated shelf, which comprises: a refrigerator body, including a storage room; a shelf, arranged inside the storage room; a light source, arranged at the rear end of the shelf; a power supply unit, arranged at the rear end of the shelf the rear of the storage room and supply power to the light source; and the light guide plate is arranged on the shelf and guides the light of the light source to the front of the shelf. Thereby, the length of an electrical line can be shortened, and glare by direct lighting can be suppressed.