The invention discloses a safe transportation tank for polyurethane resin. The safe transportation tank for polyurethane resin comprises a tank body, supporting legs, foot pads, a sealing cover, a locking bolt, a knob, a discharge port, a discharge valve and an extrusion and pushing device. According to the safe transportation tank for polyurethane resin, the extrusion and pushing device is arranged in the tank body, and when discharging is carried out, a hand wheel is rotated to drive a pressing plate through a screw rod so as to extrude and push downward the internal storage polyurethane resin, so that the discharging of the polyurethane resin is accelerated; a cleaning device is arranged at the bottom of a partition top plate, and the polyurethane resin adhering to the inner wall of thetank body is scraped off through a scraping head on a scraping plate, so that the cleanliness of the inside of the tank body is improved; and meanwhile, a sealing structure is arranged on an outer ring of the partition top plate, a mounting fixing frame is tightly attached to the partition top plate, and then a center ring, a first side sealing ring and a second side sealing ring seal the partition top plate, so that the polyurethane resin is prevented from passing through the gap between the extrusion and pushing device and the inner wall of the tank body, and the discharging efficiency is improved.