148results about How to "Maintain sensitivity" patented technology

A film suitable for use in an ophthalmic system is provided. The film may selectively inhibit blue light within the wavelength range of 400 nm to 460 nm to reduce phototoxic light to the eye while maintaining photopic vision, and may be color balanced to allow for the system into which the film is incorporated to be perceived as colorless to a viewer observing and / or using the system. The system may have a photopic and scotopic luminous transmission of 85% or more and a phototoxicity ratio of less than 80%. When used in an ophthalmic system or other system disposed between an observer's eye and a light source, the film may reduce the flux of blue light to the internal structures of the eye while reducing or minimizing dilation of the pupil.

A physical quantity measuring apparatus includes an oscillation drive circuit that forms an oscillation loop together with a physical quantity transducer and excites a drive oscillation of the physical quantity transducer, and a detection circuit that detects an analog detection signal outputted from the physical quantity transducer using a detection circuit first and thence converts the signal that has been detected into a digital signal using an A / D converter to output the digital signal. The oscillation drive circuit has a drive amplitude detection circuit that detects amplitude of the drive oscillation. A voltage level of a reference of the A / D converter included in the detection circuit is controlled on the basis of a detection output signal of the drive amplitude detection circuit.

A high-sensitivity and low-noise micromachined capacitive lateral accelerometer device having an input axis and a monolithic, three-axis accelerometer utilizing the device are provided. The device includes at least one electrode having a side surface normal to the input axis. A relatively large proofmass has at least one side surface normal to the input axis and extends along a width of the proofmass. The proofmass is movable against acceleration relative to the at least one electrode due to inertial force along the input axis to obtain a capacitive variation between the at least one electrode and the proofmass. The side surfaces are spaced apart to define a narrow, high-aspect ratio sensing gap which extends along substantially the entire width of the proofmass. The proofmass forms a sense capacitor with the at least one electrode.

The invention provides a system and method for analyzing and classifying the losses of a photovoltaic array. The system and method compares expected power output and to actual power output and can determine a photovoltaic string, combiner, or inverter is generating less power than expected due to at least one of snow cover, soiling, and inverter clipping. The system and method can then determine an amount of power lost during a period of time the photovoltaic string, combiner, or inverter is experiencing snow cover, soiling, or inverter clipping and determine a value of the amount of power lost during the period of time. Various user interfaces enable a user to view one or more reasons why a PV string, combiner or inverter is generating less power than expected and the value of the amount of power lost.

The invention discloses a small molecule probe based on nano-gold and aptamer and a preparation method of the small molecule probe. The small molecule probe comprises nano-gold particles, more than one type of sulfydryl modifying deoxyribonucleic acid (DNA) fragment assembled on the nano-gold particles and more than one type of aptamer which is marked by fluorescent groups, and at least a part of fragments of the more than one type of the aptamer are complemented and hybridized with the more than one type of sulfydryl modifying DNA group. The small molecule probe is short in detecting time, simple in operation, high in specificity, good in repeatability, high in accuracy, and the false positive result is effectively reduced. By means of the aptamer technology, a high detection sensibility is achieved, and various molecules can be simultaneously detected.

An improvement in monopulse radar achieves nulling of a single mainlobe jammer and multiple sidelobe jammers while maintaining the angle measurement accuracy of the monopulse ratio by cascading a multiple sidelobe canceller and a mainlobe canceller, and imposing a mainlobe maintenance technique during the sidelobe jammer cancellation process so that the results of the sidelobe jammer cancellation process do not distort the subsequent mainlobe cancellation process. In this manner, the sidelobe jammers and the mainlobe jammer are cancelled sequentially in separate processes.

A system and method for automatically segmenting a computed tomography (CT) image of a patient's lung. The method includes the steps of segmenting the CT image to acquire one or more lung regions, intensity thresholding the lung regions to generate a mask region comprising high-intensity regions corresponding to anatomical structures within the lung regions, computing a Euclidean distance map of the mask region, performing watershed segmentation of the Euclidean distance map to generate one or more sub-regions, identifying a seed point for each sub region, growing candidate regions from the seed point of each sub-region, and classifying one or more candidate regions as a lung nodule based on one or more geometric features of the candidate regions.

An active sieve device for the isolation and characterization of bio-analytes is provided, comprising a substrate for supporting the bio-analytes. The substrate comprises a plurality of interconnections and a plurality of regions, each region comprising a hole and at least one electrode embedded in or located on the substrate and electrically associated with the hole. Each region further comprises at least one transistor integrated in the substrate and operably connected to the at least one electrode and to at least one of the plurality of interconnections.

A method is provided for determining the activity of an enzyme which releases methylumbelliferone (MU) from an MU-containing substrate wherein the enzyme has a pH optimum below the pKa of MU comprising: contacting a sample suspected of containing the enzyme with the MU-containing substrate at a pH suitable for activity of the enzyme to allow release of MU by the enzyme; contacting the sample with light of a wavelength in the range of about 310 nm to about 350 nm; determining fluorescence produced by the released MU, thereby determining the activity of the enzyme. This real time method provides improved diagnostic methods, for example for diseases associated with an abnormal level of activity of a glycosidase. The real time assay also can be used to screen compounds for their ability to modulate enzyme activity using MU-containing substrates.

A low power super regenerative receiver and a method of reducing the power consumption of the low power super regenerative receiver are provided. The super regenerative receiver includes: an oscillator having a start-up time period starting oscillation that varies according to an existence of an input signal; and a power controller supplying power within the start-up time period of the oscillator.

An active medical device able to discriminate between tachycardias of ventricular origin and of supra-ventricular origin. Two distinct temporal components (UnipV, BipV) are obtained corresponding to two EGM signals of ventricular electrograms. The diagnosis operates in at least two-dimensional space to determine, from the variations of one temporal component as a function of the other temporal component, a 2D characteristic representative of a heart beat and, this, for a reference beat collected in Sinus Rhythm (SR) in the absence of tachycardia episodes, and for a heart beat in Tachycardia. The discrimination of the tachycardia type, VT or SVT, is then realized by a classifier operating a comparison of the two current and reference 2D characteristics.

A piezoelectric vibration gyro element formed by etching from a quartz substrate of a Z-plate, includes: a base portion, a pair of vibration arms for detection extending from the base portion toward both sides thereof in the direction of Y-axis, a pair of coupling arms extending from the base portion toward both sides thereof in the direction of X-axis, pairs of vibration arms for driving extending from the end portions of the coupling arms toward both sides thereof in the direction of Y-axis, four beams extending from the base portion, and support portions connected to the ends of the beams, which are all arranged on an XY plane; wherein the beams are extending in the directions of about 30° or about 60° with the X-axis as a reference.

In an inductively coupled radio frequency identification (RFID) system deployed in animal and livestock applications, reading system efficacy can be compromised by animal movement on, around, or near metal structures prone to producing sonic frequencies. Such is the case, for example, when a walk-by antenna is mounted at the entry door of a livestock transport trader, and animals transit on a metallic ramp and metallic trader floor. Associated with the observable acoustic noise are subtle disturbances in the magnetic field surrounding the antenna due to vibrating metal altering the reluctance of the antenna's magnetic field. This acoustic noise manifests itself as an electrical noise phenomenon that interferes with the signals of certain types of identification tags which rely on amplitude modulation. The detrimental effects of acoustic noise from metal structures can be mitigated by using a multi-loop antenna that limits the spatial distribution of the transmitted magnetic field and cancels close by magnetic field disturbances.

An image sensor device is disclosed. The image sensor device comprises a substrate having a pixel region and at least one integrated circuit in the substrate of the pixel region. A photodiode is disposed on the substrate of the pixel region, comprising a lower electrode, a transparent upper electrode and a photoelectric conversion layer. The lower electrode is disposed on the substrate and is electrically connected to the integrated circuit. The photoelectric conversion layer is disposed on the lower electrode and has a submicron structure therein. The transparent upper electrode is disposed on the photoelectric conversion layer.

A hygienic glove having multiple removable layers. Each outer and successive layer has a tab means, whereby the outer and successive layers can be readily torn off or removed from the remainder of the glove, leaving the remaining layers, and finally the last layer, in place on the wearer's hand.

A magnetism measuring device includes: a wall forming a cell portion; an opening which is open to a portion of the wall; a sealing material which seals the opening; a coating layer which covers the sealing material on an inside of the cell portion; and an alkali metal gas which is sealed in the cell portion.

An optical probe assembly for conveying Raman pump light to a specimen and for conveying a Raman signature from the specimen to an optical spectrum analyzer, the optical probe assembly comprising a light guide, wherein the light guide comprises a core region and a surrounding cladding region, wherein the core region is constructed so as to minimize the creation of a relatively broadband spurious background noise signal when conveying the Raman pump light to the specimen, and the cladding region is constructed so as to satisfy the wave guiding reflection requirements of the Raman pump light and the Raman signature. A Raman spectroscopy system comprising: a laser for producing Raman pump light; an optical probe assembly for conveying the Raman pump light to a specimen and for conveying a Raman signature from the specimen to an optical spectrum analyzer, the optical probe assembly comprising a light guide, wherein the light guide comprises a core region and a surrounding cladding region, wherein the core region is constructed so as to minimize the creation of a relatively broadband spurious background noise signal when conveying the Raman pump light to the specimen, and the cladding region is constructed so as to satisfy wave guiding reflection requirements of the Raman pump light and the Raman signature; and an optical spectrum analyzer for receiving the Raman signature of a specimen and identifying and characterizing the specimen based upon the spectrum of the Raman signature. A method for conducting Raman spectroscopy comprising: producing Raman pump light; conveying the Raman pump light through an optical probe assembly to a specimen and conveying a Raman signature from the specimen through the optical probe assembly to an optical spectrum analyzer, the optical probe assembly comprising a light guide, wherein the light guide comprises a core region and a surrounding cladding region, wherein the core region is constructed so as to minimize the creation of a relatively broadband spurious background noise signal when conveying the Raman pump light to the specimen, and the cladding region is constructed so as to satisfy wave guiding reflection requirements of the Raman pump light and the Raman signature; and identifying and characterizing the specimen based upon the spectrum of the Raman signature.

The present invention relates to formulations for use as enteric coatings. More particularly, the present invention relates to a formulation comprising a dry blend of food grade ingredients that can be readily dispersed in water. This dispersion exhibits low viscosity and can easily be coated onto solid dosage forms through spraying and the like to provide an enteric coating on the solid dosage form.

The present invention relates to formulations for use as enteric coatings. More particularly, the present invention relates to a formulation comprising a blend of food grade ingredients that can be readily dispersed in water. This dispersion exhibits low viscosity and can easily be coated onto solid dosage forms through spraying and the like to provide an enteric coating on the solid dosage form.

A glucose sensor for intravascular measurement of glucose concentration wherein the sensor is arranged to measure glucose concentration by monitoring the lifetime of the fluorophore, the sensor comprising:—an indicator system comprising a receptor for selectively binding to glucose and a fluorophore associated with said receptor, wherein the fluorophore has a life-time of less than 100 ns;—a light source;—an optical fibre arranged to direct light from the light source onto the indicator system; —a detector arranged to receive fluorescent light emitted from the indicator system; and—a signal processor arranged to determine information related to a fluorescence lifetime of the fluorophore based on at least the output signal of the detector.

An ambidextrous or hand specific glove with a widened cuff area to aid in donning or doffing the glove is disclosed, together with a former for fabricating the glove and a method of fabricating the same. The glove may further include a bead on the cuff to resist tearing when the glove is put on or taken off. The glove may be fabricated on a continuous, automated chain machine or a batch or semi-batch machine. While the cuff region on the former for fabricating the glove is elliptical in cross-section and is flared, the region of the former on which the end of the glove is fabricated is circular in cross-section and thus allows the beading process to be successfully undertaken. The thumb region and finger regions of the glove may each be provided with a flexible hinge region that enables a user to more easily bend their thumb and fingers.

Systems and methods for reducing interference in an enhanced radio receiver from a transmitter when both are located in the same aircraft are provided. The enhanced radio receiver detects and attenuates a signal from the transmitter, without attenuation or interference with other desired signals. An enhanced radio transmitter may inform the enhanced radio receiver of the frequency of transmission via a data communication path such that the enhanced radio receiver attenuates the transmitted frequency for the duration of transmission.

A sensor device for sensing air flow speed at the exterior of an aircraft, comprising a substrate having an upper side on which is mounted a diaphragm over an aperture or recess in the substrate, the diaphragm being thermally and electrically insulative, and mounting on its upper surface a heating element comprising a layer of resistive material, and wherein electrical connections to the heating element are buried in the diaphragm and / or the substrate, and provide electrical terminals at the lower side of the substrate. The heating element is exposed to the environment, but the remaining electrical parts of the device are not exposed.

Embodiments of a dissolved oxygen sensor are disclosed herein. Embodiments as disclosed herein may include a window of optically transparent material disposed in an opening in a fluid flow path, where a luminophor is attached to the side of the window exposed to the fluid in the flow path. An optical probe may be disposed opposite the window from the fluid flow path on an axis at an angle to the window fluid flow path. The optical probe includes an excitation light source for illumination of the luminophor and a reference light source. An optical reception guide is configured to conduct light from the luminophor to a photodiode adjacent to the end of the optical reception guide distal the window when the luminophor is illuminated by the excitation light source. The optical probe is configured to determine a measure of oxygen concentration of the fluid in the flow path. The optical reception guide and photodiode may be aligned on axis, where the axis may be substantially parallel with the axis on which the optical probe is aligned.

This invention relates to enhancing sensitivity of cytotoxic drugs by targeting their interfering mechanisms induced in the tumor microenvironment which lead to drug resistance, using combinatorial therapy with carboxyamidotriazole orotate. Specific doses of cytotoxic drugs are titrated with carboxyamidotriazole orotate to improve the sensitivity and anticancer activity of cytotoxic drugs.