31results about How to "Meet different clinical needs" patented technology

The invention provides a gelatin embolism microsphere and a preparation method and an application thereof. The preparation method of the gelatin embolism microsphere comprises the following steps of: (1) preparing a gelatin aqueous solution of which the concentration is 10-50 percent g / ml; (2) adding the gelatin aqueous solution prepared in the step (1) into an emulsifier-containing oil phase of which the temperature is 50-60 DEG C, stirring for 10 minutes, lowering the temperature to 2-5 DEG C, stirring for 30 minutes at the stirring speed of 100-900 revolutions per minute, and standing to precipitate the microsphere; (3) pouring the oil phase out, repeatedly washing the oil phase left on the surface of the microsphere with acetone, and filtering the microsphere out; and (4) adding the microsphere obtained in the step (3) into a crosslinking agent aqueous solution of which the pH is 8-9 and the concentration is 1-15 percent g / ml, reacting at the temperature of 4 DEG C for 0.5-25 hours, and washing the microsphere with distilled water. The gelatin embolism microsphere provided by the invention is crosslinked uniformly, is regularly spherical, and is convenient for screening grading and accurate marking of the particle diameter; and the degradation time and elasticity of the gelatin embolism microsphere are more suitable for clinical application.

The invention provides a traditional Chinese medicine pellet and a preparation method thereof, and particularly relates to a traditional Chinese medicine pellet preparation and a preparation method of the traditional Chinese medicine pellet preparation. The traditional Chinese medicine pellet preparation is prepared by six traditional Chinese medicines including radix astragali, fructus ligustri lucidi, hirudo, radix et rhizoma rhei, radix pseudostellariae and fructus lycii and other medical auxiliary materials. The traditional Chinese medicine pellet preparation contains a traditional Chinese medicine composition, a diluent and a disintegrant according to a specific ratio. The prepared pellet is obvious in moistureproof effect, high in pellet roundness and bioavailability, uniform in particle size distribution, relatively high in yield and excellent in drug release performance, and provides better selection for clinical medication.

The invention relates to an injectable composite bone cement with photothermal effect and its preparation method and application. The bone cement contains the following components in weight percent: 30-65% of biological glass powder, 5-30% of titanium nitride nano powder , sodium alginate mixed solution 30‑40%. Compared with the prior art, the bone cement of the present invention not only has the characteristics of being plastic and easy to operate, but also has a significant photothermal effect, which can be regulated by changing the amount of titanium nitride nanoparticles added; the bone cement prepared The process equipment of cement is simple, easy to operate, low in cost, good injectability can be obtained without adding cross-linking agent, and minimally invasive treatment can be realized; it can be used to prepare bone filler after surgical resection of bone tumor and applied to bone tissue Engineering bone repair, regeneration and other fields.

The present invention provides an implantable nerve stimulation device with multiple frequency modes, including a control circuit for determining the frequency modes, the frequency modes include independent frequency modes and the same frequency mode, and multiple frequency modes are provided in the independent frequency mode Different pulse frequencies, providing a unique pulse frequency in the same frequency mode; a signal output circuit, used to output multiple groups of pulse signals according to the multiple different pulse frequencies in the independent frequency mode, wherein different groups of The pulse frequencies of the pulse signals are different. In the same frequency mode, multiple groups of pulse signals are output according to the unique pulse frequency, wherein the pulse frequencies of each group of pulse signals are the same.