The invention relates to a backpressure balanced type liquid high pressure regulation device and belongs to the field of static pressure measurement and calibration. The backpressure balanced type liquid high pressure regulation device comprises a pneumatic hydraulic pump, a control stop valve, a balanced stop valve, a high-pressure pipeline, a pressure sensor, a test port, a ball screw assembly, a worm and gear reducer, a servo motor and a backpressure balanced type regulation device, wherein the backpressure balanced type regulation device comprises a ball screw pair output shaft, a slotted conical end fastening screw, a sealing group A, a guide wearing ring, a bracket, a sealing group B, a slotted flat end fastening screw, an O-shaped ring, an inner hexagonal cylindrical screw, a spring gasket, a sealing group C, a pressure regulating piston cylinder, a bushing, a pressure regulating piston, a supporting ring, a nut, a retainer ring, a limiting screw plug, a top column, a backpressure piston, a baffle ring, a backpressure piston cylinder and a transition cylinder. According to the device, the problem that the high oil pressure has large axial thrust on the piston in the actual high-pressure using process in a variable volume pressure control technology is solved, and the high-pressure pressure is easily and accurately regulated.