The invention discloses a modularized high-frequency link power conversion system of a plug-and-play structure, and belongs to the technical field of power electronics. The system comprises a power supply module with a plug-and-play port, a control module with a plug-and-play port, a signal processing module with a plug-and-play port, one or more power modules with plug-and-play ports, one or more high-frequency isolation transformers and a mother board with multiple plug-and-play ports. The power supply module, the control module, the signal processing module and the power modules are inserted into the corresponding plug-and-play ports respectively of the mother board through respective play-and-plug ports, and signal transmission is achieved through a signal connection bus on the mother board. The power modules are connected through power connection buses, and the power modules and the high-frequency isolation transformers are connected through power connection buses. The plug-and-play function of the power conversion system can be achieved, and production, assembling and maintenance are facilitated through a modularized structure.