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30results about How to "Short duration of treatment" patented technology

Assessment of CTLA-4 polymorphisms in CTLA-4 blockade therapy

The invention provides methods for predicting responsiveness of a subject to therapy with a CTLA-4 blocking agent. The methods involve assaying for at least one CTLA-4 polymorphism in the subject and predicting responsiveness of the subject to therapy with a CTLA-4 blocking agent based on presence or absence of a CTLA-4 polymorphic allele in the subject. The methods can further comprise selecting a treatment regimen with a CTLA-4 blocking agent in a subject based upon presence or absence of a CTLA-4 polymorphic allele in the subject. The methods can further comprise administering a CTLA-4 blocking agent to the subject according to the selected treatment regimen. Kits comprising a CTLA-4 blocking agent and means for assaying one or more CTLA-4 polymorphisms, optionally including a vaccine, are also provided.
Owner:UNIV OF SOUTHERN CALIFORNIA +1

Emulsifiable paste for treating urticaria papulosa and preparation method thereof

The invention discloses an emulsifiable paste for treating urticaria papulosa. The emulsifiable paste is prepared from the following raw materials in parts by weight: 1 to 2 parts of butyric acid hydrocortisone, 13 to 17 parts of erythromycin lactobionate, 7 to 9 parts of chlorpheniramine maleate and 1000.5 to 1071.5 parts of auxiliary materials. The preparation method comprises the following steps: A) substrate preparation: taking the auxiliary materials of 63 parts of glycerinum, 150 parts of vaseline, 100 parts of cetanol, 100 parts of liquid paraffin, 1 part of hydroxy benzene acetic acid and 600 parts of purified water, placing into a vessel, heating at the temperature of 85 to 90 DEG C, then, adding 25 parts of leveling agent O, stopping heating, and stirring uniformly until generation of condensation so as to acquire O / W type emulsifiable paste substrate; B) emulsifiable paste preparation: taking powder raw materials of 1.5 parts of the butyric acid hydrocortisone, 15 parts of the erythromycin lactobionate and 8 parts of the chlorpheniramine maleate, adding into the O / W type emulsifiable paste substrate in step A, and stirring uniformly; C) packaging: respectively taking 15 parts of the emulsifiable paste, and sub-packaging with plastic cases. According to the emulsifiable paste, stimulation reaction and anaphylactic reaction of skin can be avoided; besides, the emulsifiable paste is short in therapy time-effect, high in cure rate, simple in preparation process, convenient to produce and process and definite in therapy effect.
Owner:王卫武

Chinese medicine for treating cough

The invention discloses a Chinese medicine for treating cough. The Chinese medicine consists of the following components in part by weight: 2 to 4 parts of white mulberry root-bark, 2 to 4 parts of cortex lycii radicis, 2 to 4 parts of codonopsis pilosula, 3 to 5 parts of rhizoma anemarrhenae, 3 to 5 parts of scutellaria baicalensis, and 3 to 5 parts of liquorice. The medicine is high in treatment efficiency, and short in a treatment course and does not have side effects.
Owner:周春根

Medicament for treating chronic migraine and general headache

The invention relates to a medicine for curing chronic migraine, which adopts the traditional Chinese herbal medicine, such as angelica sinensis, hemlock parsley, angelica dahurica, asarum, notopterygium and edebouriella seseloides, which has the advantages of simple making method and low cost as the major component of the medicine. The medicine of the invention has the advantages of convenience for carrying and taking for the sick due to infusing-take adopted, great effect for curing chronic migraine, and suitability for the sick of various ages.
Owner:陈铭

Nasal plug for spleen deficiency type epistaxis

The invention discloses a nasal plug for spleen deficiency type epistaxis. The nasal plug comprises a base, a handle, a soft plug and a sealing cover, wherein a boss is disposed between the soft plug and the handle, hemostatic cotton is disposed at the upper end of the soft plug, the lower end of the soft plug is fixedly adhered to the base, the sealing cover is connected with the base in a fastened manner and wraps the soft plug, a medicine bag is disposed in the middle of the soft plug, a plurality of medicine spraying passages are arranged between the medicine bag and the hemostatic cotton and between the medicine bag and the wall of the soft plug, and the boss is fixedly adhered to the handle; a powdered traditional Chinese medicine composition is loaded into the medicine bag, and the traditional Chinese medicine composition comprises, by weight, 45-60g of radix astragali, 45-60g of rhizoma cimicifugae, 45-60g of monkshood, 45-60g of bighead atractylodes rhizome, 30-45g of betel nut, 30-45g of rhizoma atractylodis, 30-45g of gypsum, 30-45g of rhizoma coptidis, 10-20g of pomegranate bark, 10-20g of common cephalanoplos herb, 10-20g of pyrrosia lingua, 10-20g of lotus plumule, 10-20g of pseudo-ginseng, 10-20g of peanut coat, 10-20g of lalang grass rhizome, 10-20g of puffball and 10-15g of chrysanthemum. The nasal plug is simple in structure, convenient to use, simple in medicine proportion and composition, fast in hemostasis and capable of shortening a treatment course.
Owner:严中明

Ulcer paste and preparation method thereof

The invention discloses an ulcer paste. The ulcer paste is composed of the following components: 1-5 million units of nystatin, 3-10 ml of lidocaine, 3-8 g of montmorillonite powder, 2-10 ml of a sodium chloride injection with a mass concentration of 0.9%, 10-25 [mu]g of a recombinant human granulocyte colony-stimulating factor injection, 5-10 ml of a Kangfuxin solution, 0.8-1.2 g of metronidazoletablets, 0.1-1 g of chitosan, 0.1-2 ml of acetic acid, and 0.2-10 g of pectin. The preparation method comprises the steps of performing primary wrapping by using the chitosan, and performing secondary wrapping by using the pectin. The prepared ulcer paste has strong adhesion and no odor, and multiple ingredients in the formula cooperate with one another, so that the ulcer paste has anti-inflammatory, analgesic, wound healing promoting, strong-adhesion, safe and effective therapeutic effects on patients with oral ulcers after chemotherapy and hematopoietic stem cell transplantation.
Owner:LIUZHOU WORKERS HOSPITAL

Hemostatic nasal plug and manufacturing method thereof

The invention discloses a hemostatic nasal plug. The nasal plug comprises a base, a handle, a soft plug and a sealing cover, wherein a boss is disposed between the soft plug and the handle, hemostatic cotton is disposed at the upper end of the soft plug, the lower end of the soft plug is fixedly adhered to the base, the sealing cover is connected with the base in a fastened manner and wraps the soft plug, a medicine bag is disposed in the middle of the soft plug, a plurality of medicine spraying passages are arranged between the medicine bag and the hemostatic cotton and between the medicine bag and the wall of the soft plug, and the boss is fixedly adhered to the handle; a powdered traditional Chinese medicine composition is loaded into the medicine bag, and the traditional Chinese medicine composition comprises, by weight, 45-60g of herba schizonepetae, 45-60g of radix sileris, 45-60g of radix platycodi, 45-60g of fructus aurantii, 30-45g of straight ladybell root, 30-45g of radix ophiopogonis, 30-45g of rhizoma anemarrhenae, 30-45g of jasmine, 10-20g of rhizoma nelumbinis, 10-20g of catechu, 10-20g of red halloysite, 10-20g of tortoise shell, 10-20g of pollen typhae, 10-20g of folium ilicis purpurea, 10-20g of bletilla striata, 10-20g of gallnut and 10-15g of liquorice. The nasal plug is simple in structure, convenient to use, simple in medicine proportion and composition, fast in hemostasis and capable of shortening a treatment course.
Owner:严中明

Chinese medicine preparation for treating diabetic eye complication

The Chinese medicine preparation for treating diabetes and chronic diabetic retinopathy includes one recipe I and one recipe II capable of being used alone. The recipe I consists of astragalus root, gastrodia tuber, glossy ganoderma and other four kinds of Chinese medicinal materials in certain weight proportion; and the recipe II consists of astragalus root, gastrodia tuber and glossy ganoderma in certain weight proportion. The recipe I and the recipe II are prepared through conventional preparation process into medicine powder or capsule. During treatment, the recipe I medicine is first taken until basically recovering, and the recipe II medicine is then taken for curing radically. Compared with available technology, the present invention has the advantages of determined curative effect and no side effect.
Owner:王忠智

Medicament for treating myofascial pain syndrome

InactiveCN105641080ARemove the first pass effectLow priceAntipyreticAnalgesicsSide effectMedicine
The invention provides a medicament for treating myofascial pain syndrome. The medicament formula comprises a composition A prepared from the following components in parts by weight: 1-20 parts of notopterygium root, 1-20 parts of radix angelicae pubescentis, 1-15 parts of red peony root, 1-20 parts of white peony root, 1-20 parts of nodular branch of pine, 1-30 parts of garden balsam stem, 1-20 parts of sappanwood, 1-15 parts of hemlock parsley and 1-30 parts of mistletoe. Simultaneously, by adopting a external hydrotherapy method, the medicament for treating myofascial pain syndrome is convenient in treatment, eliminates the first pass effect on liver of oral medicaments, enhances the curative effect and reduces the side effect.
Owner:周霞

Intranasal delivery rhinobyon and manufacturing method thereof

The invention discloses an intranasal delivery rhinobyon. The intranasal delivery rhinobyon comprises a base, a handle, a soft plug and a sealing cap. A boss is arranged between the soft plug and the handle, hemostatic cotton is arranged at the upper end of the soft plug, the lower end of the soft plug and the base are fixed adhesively, the sealing cap is connected with the base by means of fastening and wraps the soft plug, a medicine sac is arranged in the middle of the soft plug, a plurality of medicine spraying passages are arranged between the medicine sac and the hemostatic cotton as well as between the medicine sac and the wall of the soft plug, the boss and the handle are fixed adhesively, and the medicine sac is filled with a powdery traditional Chinese medicine composition. The traditional Chinese medicine composition comprises 45-60g of largetrifoliolious bugbane rhizomes, 45-60g of coptis roots, 45-60g of shaved cinnamon bark, 45-60g of villous amomum fruit, 30-45g of officinal magnolia bark, 30-45g of angelica sinensis, 30-45g of wrinkled gianthyssop herb, 30-45g of perilla leaves, 10-20g of barbed skullcap herb, 10-20g of pomegranate peel, 10-20g of common bletilla tubers, 10-20g of hairyvein agrimonia herb, 10-20g of cacumen platycladi, 10-20g of ramie roots, 10-20g of teasel roots, 10-20g of ocher and 10-15g of liquorice. The intranasal delivery rhinobyon is simple in structure, convenient to use, simple in medicine ratio and components, quick in hemostasis and shorter in treatment course.
Owner:严中明

A kind of traditional Chinese medicine product for invigorating stomach and preparation method thereof

The invention discloses a stomach invigoration healthcare product and a preparation method thereof. The stomach invigoration healthcare product is characterized by consisting of dandelions, processed rheum officinale, swimming crab chitosan, calcined oyster shells, fingered citron, fructus amomi volatile oil and medicinal auxiliary materials. In the prescription, the swimming crab chitosan and the calcined oyster shells have functions of inhibiting gastric acid secretion, protecting gastric mucosa and suppressing bacteria; the dandelion and the processed rheum officinale have the functions of clearing heat, removing toxin and preventing bacteria; the fructus amomi and the fingered citron have the functions of tonifying the spleen and stimulating appetite, regulating qi and alleviating pain as well as promoting digestion. The prescription is based on the idea of 'treatment based on syndrome differentiation'of the traditional Chinese medicine, medicines are taken reasonably, and thus the effects of treating both symptoms and root causes can be achieved. Experiment tests demonstrate the scientificity and the effectiveness of the prescription, and the prescription can be developed into stomach invigoration healthcare products or medicines with pharmacologic actions of protecting gastric mucosa, preventing gastric ulcer and promoting digestion. The stomach invigoration healthcare product has the advantages of being simple in component, short in treatment course, rapid in effect taking, good in treatment effect and free of toxic or side effect, and different from conventional stomach medicines, the stomach invigoration healthcare product is a formula and a product which is very good in effect on gastric ulcer and dyspepsia.
Owner:GUANGXI UNIV OF CHINESE MEDICINE

Rhinobyon for treating epistaxis caused by liver heat

InactiveCN105214024ASimple ratio compositionSimple structureSurgeryMedical devicesRegimenPollen
The invention discloses a rhinobyon for treating epistaxis caused by liver heat. The rhinobyon comprises a base, a handle, a soft plug and a sealing cap. A boss is arranged between the soft plug and the handle, hemostatic cotton is arranged at the upper end of the soft plug, the lower end of the soft plug and the base are fixed adhesively, the sealing cap is connected with the base by means of fastening and wraps the soft plug, a medicine sac is arranged in the middle of the soft plug, a plurality of medicine spraying passages are arranged between the medicine sac and the hemostatic cotton as well as between the medicine sac and the wall of the soft plug, the boss and the handle are fixed adhesively, and the medicine sac is filled with a powdery traditional Chinese medicine composition. The traditional Chinese medicine composition comprises 45-60g of Chinese thorowax roots, 45-60g of immature bitter orange, 45-60g of angelica sinensis, 45-60g of white peony roots, 30-45g of nutgrass galingale rhizomes, 30-45g of fructus aurantii, 30-45g of Szechwan Chinaberry fruit, 30-45g of corydalis tubers, 10-20g of cattail pollen, 10-20g of trogopterus dung, 10-20g of argy wormwood leaves, 10-20g of baked ginger, 10-20g of garden burnet roots, 10-20g of humifuse euphorbia herb, 10-20g of pseudo-ginseng, 10-20g of radix rubiae and 10-15g of chrysanthemum. The rhinobyon is simple in structure, convenient to use, simple in medicine ratio and components, quick in hemostasis and shorter in treatment course.
Owner:严中明

Nasal plug for epistaxis and manufacturing method thereof

The invention discloses a nasal plug for epistaxis. The nasal plug comprises a base, a handle, a soft plug and a sealing cover, wherein a boss is disposed between the soft plug and the handle, hemostatic cotton is disposed at the upper end of the soft plug, the lower end of the soft plug is fixedly adhered to the base, the sealing cover is connected with the base in a fastened manner and wraps the soft plug, a medicine bag is disposed in the middle of the soft plug, a plurality of medicine spraying passages are arranged between the medicine bag and the hemostatic cotton and between the medicine bag and the wall of the soft plug, and the boss is fixedly adhered to the handle; a powdered traditional Chinese medicine composition is loaded into the medicine bag, and the traditional Chinese medicine composition comprises, by weight, 45-60g of dried ginger, 45-60g of amomum tsao-ko kernel, 45-60g of monkshood, 45-60g of oven earth, 30-45g of rhizoma atractylodis, 30-45g of medicated leaven, 30-45g of bighead atractylodes rhizome, 30-45g of poria cocos, 10-20g of cirsium japonicum, 10-20g of sanguisorba officinalis, 10-20g of folium artemisiae argyi, 10-20g of airpotato yam rhizome, 10-20g of ochre, 10-20g of red halloysite, 10-20g of bletilla striata, 10-20g of hairyvein agrimony and 10-15g of chrysanthemum. The nasal plug is simple in structure, convenient to use, simple in medicine proportion and composition, fast in hemostasis and capable of shortening a treatment course.
Owner:严中明

Far infrared oxygen enrichment hydrotherapy device

The invention provides a far infrared oxygen enrichment hydrotherapy device which comprises a common bathing pool, an oxygen supplier, a pressurizing pump, a pressure-regulating device and a water moxibustion device, wherein the common bathing pool is provided with a heating pump connected with a body of the common bathing pool; the oxygen supplier is connected with a water outlet pipe and provides oxygen for liquid; the pressurizing pump is connected with the water outlet pipe of the common bathing pool and provides pressure for lifting the liquid; the pressure-regulating device is connectedwith the pressurizing pump and can increase the liquid pressure; the water moxibustion device is connected with the pressure-regulating device to generate a water current for water moxibustion massage; the liquid temperature of the common bathing pool can be regulated to be high, middle and low through the heating pump so that the environment with dissolved oxygen of different quantities and far infrared wavelengths of different strengths can be generated, the surface of the human body can be massaged by the water current generated by the water moxibustion device and the efficacy of effectively stimulating the massage points and promoting the circulating metabolism can be achieved.
Owner:ROSACE INT

Acupoint application conducive to metabolism

InactiveCN105796887APlay a health effectAdjust physiological and biochemical functionsAnthropod material medical ingredientsDigestive systemDiseaseCannabis
The invention relates to an acupoint application conducive to metabolism. The acupoint application comprises a base layer, a protective layer and a paste, wherein the paste is prepared from the following raw materials by weight: 12-14g of angelica sinensis, 6-9g of swan eggs white, 11-15g of peach kernel, 3-5g of lobelia clavata, 6-9g of fructus cannabis, 20-30g of sophora flower buds, 5-8g of cistanche salsa, 4-6g of semen cassia, 1-2g of plantain herb, 12-15g of dried radix rehmanniae, 6-9g of radix polygonati officinalis, 12-15g of pericarpium citri reticulatae, 6-8g of poria cocos, 14-16g of raw rhizoma atractylodis macrocephalae, 20-25g of Chinese yam, 6-9g of radix ophiopogonis and 5-7g of scrophularia ningpoensis. The acupoint application is prepared by the following steps: mixing and cleaning the raw materials; soaking the raw materials with constant-temperature medicinal vinegar for 15-20 minutes; carrying out ultrafine grinding for 60-70 minutes, and screening the powder through a 100-mesh sieve; and adding medical Vaseline to form the paste. Through a perfect and reasonable formula, the treatment effect can be greatly improved; the treatment time is shortened; the acupoint application has a relatively good effect on constipation, and has a certain health effect on the stomach through cooperation with shredded ginger; the surface acupoints are stimulated through moxa-moxibustion; the physiological and biochemical functions of a human body can be effectively regulated; and diseases can be prevented.
Owner:刘洋

Borneol fluorine rapid-healing scaling liquid

The invention relates to a medicine for treating scale, and in particular relates to a borneol fluorine rapid-healing scaling liquid which is prepared from the following materials by weight: 2-3g of borneol, 2.5-3g of dried alum, 2-3g of norfloxacin, and 480-520g of normal saline of 0.9%. In the prescription, the borneol has the functions of clearing away heat and toxic materials, cooling blood, preventing corrosion and relieving itching, diminishing swelling and relieving pain; the dried alum has the functions of antibiosis, sore healing, muscle regeneration and scab prompting; the norfloxacin has the functions of inflammation diminishing and antibiosis; and the normal saline of 0.9% has the functions of cleaning and antibiosis and can be used as a lyase solvent and a preservative; the borneol fluorine rapid-healing scaling liquid combines the four medicines, the prescription is rigorous and scientific, and the curative effect is definite, so that the borneol fluorine rapid-healing scaling liquid is applicable to I-grade, II-grade and partial III-grade scale, and is short in treatment course, rapid to heal and remarkable in curative effect when being compared with similar medicines for treating scale.
Owner:徐斌

Mind-tranquillizing traditional Chinese medicine composition and preparation method thereof

The invention relates to a mind-tranquillizing traditional Chinese medicine composition, which belongs to the technical field of a traditional Chinese medicine, the traditional Chinese medicine composition comprises the following components in parts by weight: 20-50 parts of anemarrhena; 10-30 parts of Chinese gall; 10-30 parts of Plantain seed; 10-30 parts of lily; 5-20 parts of ginseng; 5-20 parts of Poria cocos; 5-20 parts of lotus seeds; 5-20 parts of wolfberry; 0.5-1 part of Radix Rehmanniae Preparata; and 0.5-1 part of lucid ganoderma. The traditional Chinese medicine composition is scientific in science, reasonable in composition, and safe and reliable, has no side effects, and has quick effect on efficacy. The traditional Chinese medicine composition can effectively alleviate the symptoms of restlessness, insomnia, and palpitation, and the treatment time is short and the effect is ideal.
Owner:石羽

Conscious-promoted medicament for coma patients and use method thereof

The invention relates to the technical field of traditional Chinese medicine preparations, and discloses a conscious-promoted medicament for coma patients, the conscious-promoted medicament is composed of a traditional Chinese medicine electuary and a traditional Chinese medicine decoction, the traditional Chinese medicine electuary comprises the following components in parts by weight: 0.8-1 part of artificial musk and 0.4-0.6 part of calculus bovis; the traditional Chinese medicine decoction is prepared from the following components in parts by weight: 11-13 parts of pericarpium citri reticulatae, 8-10 parts of rhizoma pinelliae, 10-14 parts of caulis bambusae in taeniam, 18-22 parts of poria cocos 20g, 13-17 parts of peach kernels, 8-10 parts of flos carthami, 18-22 parts of radix angelicae sinensis, 10-14 parts of rhizoma chuanxiong, 10-14 parts of radix curcumae, 8-10 parts of radix rehmanniae, 5-7 parts of radix et rhizoma rhei 6 g and 5-7 parts of radix glycyrrhizae preparata. The conscious-promoted medicament is composed of traditional Chinese medicine electuary and traditional Chinese medicine decoction, Neiguan acupoint acupuncture is matched, theawakening time of patients with disturbance of consciousness can be effectively shortened, social and family economic burdens can be reduced, clinical popularization can be carried out after a systematic therapy is formed for coma after traumatic brain injury, and the method is simple, convenient, easy to implement, quick in effect taking, short in treatment course and facilitates clinical observation.
Owner:周虹

Nasal plug for lung heat type epistaxis

The invention discloses a nasal plug for lung heat type epistaxis. The nasal plug comprises a base, a handle, a soft plug and a sealing cover, wherein a boss is disposed between the soft plug and the handle, hemostatic cotton is disposed at the upper end of the soft plug, the lower end of the soft plug is fixedly adhered to the base, the sealing cover is connected with the base in a fastened manner and wraps the soft plug, a medicine bag is disposed in the middle of the soft plug, a plurality of medicine spraying passages are arranged between the medicine bag and the hemostatic cotton and between the medicine bag and the wall of the soft plug, and the boss is fixedly adhered to the handle; a powdered traditional Chinese medicine composition is loaded into the medicine bag, and the traditional Chinese medicine composition comprises, by weight, 45-60g of honeysuckle, 45-60g of rhubarb, 45-60g of radix ophiopogonis, 45-60g of dried radix rehmanniae, 30-45g of rhizoma anemarrhenae, 30-45g of cacumen biotae, 30-45g of rhizoma coptidis, 30-45g of bletilla striata, 10-20g of shepherdspurse herb, 10-20g of radix dipsaci, 10-20g of cockscomb flower, 10-20g of folium artemisiae argyi, 10-20g of lignum dalbergiae odoriferae, 10-20g of gallnut, 10-20g of sophora flower, 10-20g of sanguisorba officinalis and 10-15g of liquorice. The nasal plug is simple in structure, convenient to use, simple in medicine proportion and composition, fast in hemostasis and capable of shortening a treatment course.
Owner:严中明

Drug for treating asthma

The invention relates to a drug, in particular to a drug for treating asthma.The drug for treating asthma is composed of, by weight, 15-20 parts of Folium eriobotryae, 10-15 parts of dandelion, 1-3 parts of zinc gluconate, 5-10 parts of Rhizoma pinelliae preparata and 3-9 parts of borneol.The drug is prepared partly from Western medicine and partly from traditional Chinese medicine, and the Western medicine and the traditional Chinese medicine are synergistic and low in cost, so that the drug can be popularized and used on a large scale.Chinese medicine materials which are pure natural are adopted, so that side effect of the drug is reduced; the drug is packaged into tablets, so that convenience is brought to daily administration and carrying, the drug can be taken at any time to relieve suffering of patients during onset of asthma, and the drug is suitable for the patients of all ages and all stages to take, short in treatment course and quick in action.
Owner:JINAN ZHENGQI BIOTECHNOLOGY CO LTD +1

Muscle and bone effusion relieving powder and preparation method thereof

PendingCN113230297AStrong drug penetration and absorption capacityFast treatmentAntipyreticAnalgesicsDiseaseTraditional medicine
The invention provides a muscle and bone effusion relieving powder, which is prepared from the following components by weight: 30g of pseudo-ginseng powder; 30 g of grifola powder; 5 g of safflower powder; 30 g of rhizoma drynariae powder; 20 g of frankincense powder; 20 g of myrrh powder; 20 g of radix achyranthis bidentatae powder; and 30 g of donkey hoof nail charcoal powder. The various periarticular diseases (except for joint deformation) and various hydrops diseases of the whole body can be treated.
Owner:邱晓辉

Medicine for treating foot skin diseases

The invention discloses a medicine for treating foot skin diseases. The medicine for treating the foot skin diseases is prepared from the six pure traditional Chinese medicine extracted ingredients ofJapanese dock roots, cocklebur fruits, amur cork tree bark, fructus kochiae, herba portulacae and clematis intricata bunge. The medicine is good in treatment effect, short in treatment course, convenient to use, free of toxic and side effects, low in cost and suitable for various foot skin diseases.
Owner:吴定
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