The invention discloses an ozone concentration estimation method fusing satellite remote sensing and ground monitoring data, and belongs to the technical field of environment monitoring. The method comprises the steps of 1, collecting, preprocessing and fusing multi-source sample data to obtain input parameters; 2, based on a multilayer mapping back propagation neural network, establishing an ozone concentration estimation operation basic model; and 3, based on the influence factors, the forward time and the spatial range, searching an optimal input parameter combination of the obtained ozone concentration estimation operation basic model, and accurately estimating the ground ozone concentration according to the obtained optimal input parameter combination to obtain the spatial continuous distribution condition of the ozone concentration, and realize the ozone concentration estimation method fusing satellite remote sensing and ground monitoring data. The method has the advantages of high accuracy, high reliability and simplicity in operation, the used multi-source sample data are free and open-source, the universality is enhanced, the ozone concentration can be quickly estimated, and a continuous distribution diagram of the ozone concentration in a target area can be drawn.