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38 results about "Cornea epithelium" patented technology

Bifidobacterium animalis for relieving eye allergy and application thereof

PendingCN121592551ASenses disorderBacteriaDiseaseSwollen eyelid
The invention belongs to the technical field of microorganisms, and particularly relates to bifidobacterium animalis for relieving eye allergy and application of the bifidobacterium animalis. The invention provides an application of bifidobacterium animalis subsp. Lactis in preparation of a product for relieving eye allergy, the bifidobacterium animalis subsp. Lactis is Def +, and the preservation number is CGMCC (China General Microbiological Culture Collection Center) No.35798. The Bifidobacterium animalis subsp. Lactis Def < + > provided by the invention can relieve the eye itching symptom, relieve red and swollen eyelids, reduce conjunctiva and cornea injury, relieve eye discomfort, relieve globular conjunctivitis cell infiltration, improve corneal epithelium thickening lesion, improve the anti-inflammatory ability and improve allergic conjunctivitis, keratitis and blepharitis marginata in a targeted manner. The eye drops are high in safety and resistant to gastrointestinal fluid, and a safe and long-acting scheme is provided for eye allergic diseases.
Owner:ZHONGKE WISBIOM(BEIJING)BIOTECHNOLOGY CO LTD

Teaching model for pterygium resection operation

PendingCN121747404AEducational modelsConjunctivaPupil
The invention relates to the technical field of medical teaching models, in particular to a pterygium resection operation teaching model. Comprising a hemispherical base and further comprises a simulation eyeball, a fixing mechanism, a micro-errhysis simulation system, a pterygium simulation block, a transfusion pipeline and a conjunctival graft, the simulation eyeball used for simulating a human eyeball is arranged in the hemispherical base, the fixing mechanism is arranged in the hemispherical base, and the fixing mechanism is used for fixing the simulation eyeball in the hemispherical base. The simulated eyeball is constructed by adopting a multi-layer composite material, the simulated eyeball comprises a simulated sclera, a cornea bionic layer (comprising a cornea epithelium layer, a front elastic layer and a matrix layer), a simulated iris, a simulated pupil and a simulated conjunctiva, and each layer of material simulates a real ocular surface tissue in transparency, elastic modulus and mechanical property; students can obtain tactile feedback and visual experience close to a clinical real operation in the operation process, and the reality sense and effectiveness of micromanipulation skill training are effectively improved.
Owner:AFFILIATED PEOPLES HOSPITAL OF NINGBO UNIV

Personalized corneal contact lens microneedle device for treating corneal dilation diseases

ActiveCN224235644UEye surgeryCorneal ectasiaSurgery
The utility model provides a personalized corneal contact lens microneedle device for treating corneal dilation diseases, which comprises a fixing device and a drug delivery device, the drug delivery device comprises a drug delivery main body and a drug delivery microneedle arranged on the drug delivery main body; the fixing device surrounds the periphery of the drug delivery main body and is concentric with the drug delivery main body and embedded with the drug delivery main body; wherein the fixing device fixes the whole corneal contact lens microneedle device on the surface of a cornea through the fixing microneedle, a biomechanical effect is generated around the cornea to control the corneal curvature progress, and meanwhile, the medicine delivery microneedle is fixed in the center of the cornea; the drug delivery microneedle is used for penetrating through the cornea epithelium to reach the cornea stroma layer, so that the drug on the drug delivery main body permeates into the cornea stroma layer, and finally, the thickness and hardness of the cornea stroma layer are increased in combination with ultraviolet irradiation, and the disease progress is controlled. The treatment mode of the device is safe and efficient, and nano-drugs are not needed.
Owner:ZHONGSHAN OPHTHALMIC CENT SUN YAT SEN UNIV