The invention discloses a prefabricated concrete anti-seismic joint. The prefabricated concrete anti-seismic joint comprises a prefabricated concrete column, a prefabricated concrete beam, an upper connecting steel plate, a lower connecting steel plate, transverse bolts, vertical steel padding plates, vertical bolts and a steel cross shearing-resistant piece, wherein the transverse bolts and the vertical bolts are bolts applying prestressing force, the prefabricated concrete column is provided with a bracket, two rectangular grooves are formed in the end, away from the concrete beam, of the concrete column, and are matched the vertical steel padding plates, first transverse bolt holes are formed in the rectangular grooves respectively and used for transversely running through the concretecolumn, the cross section of the prefabricated concrete beam is in a T shape, second transverse bolt holes matched with the first transverse bolt holes are formed in the end of the concrete beam, andfirst vertical bolt holes are vertically formed in the portions, close to the end, of the concrete beam. The prefabricated concrete anti-seismic joint is easy to assemble, convenient and fast and highin anti-seismic effect.