The invention relates to a nanometer negative ion environmental-protection coating, which is characterized by being prepared from the following components in parts by weight: 10 to 30 parts of emulsion, 10 to 50 parts of deionized water, 1 to 5 parts of negative ion additive, 15 to 25 parts of titanium dioxide, 0.5 to 5 parts of accessory ingredient, and 1 to 15 parts of filler. When being coated in any indoor site, the nanometer negative ion environmental-protection coating not only achieves a decorative effect, but also can durably and effectively adsorb indoor air pollutants, releases a large number of negative oxygen ions at the same time for cleaning air, and builds a healthy environment of a natural air anion bar indoors completely for comprehensively caring life health of people. The nanometer negative ion environmental-protection coating provided by the invention is beneficial to durably improving the indoor environment, purifying indoor air, bacterium-resisting, disinfecting, purifying volatile organic cancerogens such as formaldehyde, methylbenzene, benzene, sulphur and ammonia indoors, and removing peculiar smells such as stinks, musty taste and smoke flavor; can durably release the negative oxygen ions for building the natural air anion bar indoors, and has a health-care effect for making people healthier; can effectively adsorb for a long time and settle particulate pollution of PM2.5 (Particulate Matter2.5) entering indoor from outdoor so as to enable people to escape from an outdoor haze air environment.