The invention discloses a preparation method of shock-proof modified engineering plastic and application of the shock-proof modified engineering plastic. According to the method, poly(glycerol sebacate), triallyl cyanurate, an acrylonitrile-butadiene-styrol copolymer, magnesium oxide, manganese carbonate and an ethanol solution are mixed to obtain a primary mixture, then the primary mixture is putinto a dispersion solution of kynar and acrylic resin, after an antioxidant is added for standing treatment, sediments are collected, washed and dried to obtain a modified mixture, then after the modified mixture and maleic anhydride are mixed, heating and stirring are conducted for reaction to obtain an intermediate mixture, then secondary modification is conducted to obtain a secondary modifiedmixture, then the secondary modified mixture, sepiolite fibers and deionized water are reacted in a high-pressure reaction kettle in a helium environment to obtain a high-temperature reaction material, and finally, through melt extrusion, the finished product engineering plastic is obtained. The shock-proof effect of the prepared engineering plastic is good, and thus the engineering plastic has good application prospects in the fields of household appliances, electronic engineering, automobiles and communication.