The invention discloses a system and method for wireless monitoring of the deformation of a shield tunnel. According to the system and method for wireless monitoring of the deformation of the shield tunnel, monitoring of the deformation of the shield tunnel and early warning are achieved based on measurement of pipe piece inclination. The system for wireless monitoring of the deformation of the shield tunnel comprises a Zigbee wireless sensor network, a GPRS data transmission terminal and a data processing application center, wherein the Zigbee wireless sensor network comprises multiple inclination sensing nodes which are in data communication with one another in a wireless mode, a plurality of routing nodes and a center node, monitoring data, about the variation of inclinations of adjacent blocks, collected by the Zigbee wireless sensor network are sent to the data processing application center through the GPRS data transmission terminal, the monitoring data are processed, stored and analyzed through the data processing application center, monitoring and early warning are achieved according to an analysis result and a preset threshold value, and information is fed back to management staff. According to the system and method for wireless monitoring of the deformation of the shield tunnel, a reasonable early warning threshold value is determined scientifically, the installation positions of the inclination sensing nodes are optimized, the system and device have the advantages that construction is convenient, cost is low, energy consumption is low, the monitoring precision is high and operation is stable and reliable, and the system and device are particularly suitable for wide-range long-term real-time monitoring and early warning of deformation of long shield tunnels.