The invention discloses a cleaning and disinfecting device for a medical pediatric tongue depressor. The device comprises a disinfection box, an independent disinfection cavity, a washing cavity and adrying cavity are sequentially formed in the disinfection box from left to right, a through groove is formed in one side wall, close to the disinfection cavity, of the disinfection box in a penetrating manner, the outer wall of the disinfection box is fixedly connected to a receiving hopper, first power rollers are installed on the inner wall of the receiving hopper and the inner wall of the disinfection box correspondingly, the two first power rollers are connected through a first net-shaped transmission belt, a plurality of half-crescent-shaped blocks are fixedly connected to the first net-shaped transmission belt, and a brushing mechanism is arranged between the first power rollers of the disinfection box and the disinfection box. The device is reasonable in structure, a plurality of tongue depressors can be cleaned, the cleaning and disinfection effect is good, the disinfected tongue depressors can be cleaned and dried conveniently, the tongue depressors are convenient to place, workers do not make contact with the tongue depressors any more after the tongue depressors are placed, and it is guaranteed that the tongue depressors cannot be polluted artificially after being cleaned.