The invention relates to a negative-pressure indicating drainage bottle which comprises a bottle body, wherein measurement scale lines are formed on the front surface of the bottle body, mounting bases are respectively arranged in the middle parts of the front surface, the back surface, the left side and the right side of the bottle body, hanging rings are arranged on the upper sides of the mounting bases, a bottle cap is arranged on the upper side surface of the bottle body, a vacuum indicator, a drainage opening and an extraction opening are arranged on and formed in the bottle cap in sequence from left to right, the drainage opening is connected with a drainage tube through a Ruhr connector, a reflux valve is arranged in the middle of the drainage tube, a tube clamp is arranged on the end of the drainage tube, a check valve is arranged on the upper end of the extraction opening, an extraction chamber is arranged outside the extraction opening, a connecting tube is connected to the right end of the extraction chamber, and a minipump is connected to the other end of the connecting tube. The negative-pressure indicating drainage bottle has the advantages of simple structure, safety, accuracy, good use effect and strong practicability.