The invention discloses a sludge concentration, desiccation and filter pressing system. The sludge concentration, desiccation and filter pressing system is mainly formed by connecting a sludge gravity concentration basin, a dewatered sludge feed pump, a reaction mixer, a folded screw type sludge dewaterer, a sludge specific resistance conditioning device, a middle delivery pump, a sludge reaction tank, a fed sludge pressing pump and a diaphragm type plate-frame filter press in sequence. The sludge concentration, desiccation and filter pressing system is characterized in that a dosing opening of the sludge specific resistance conditioning device is connected with a conditioner dosing device through a pipeline; the diaphragm type plate-frame filter press is provided with a diaphragm type plate frame wrapped by filter cloth, an inner cavity of the diaphragm type plate frame is connected with a pressurization water tank through a pressurization branch pipe, and a pressure regulating device is arranged on the position, between the pressurization branch pipe and the pressurization water tank, of a header pipe. The system integrates the processes of sludge concentration, mechanical dewatering, specific resistance conditioning, curing conditioning and desiccation, lowers sludge moisture content to below 60%, and has the advantages of automatically running, automatically discharging and saving energy.