37 results about "Albumin urine" patented technology

The invention relates to a urinary microalbumin (U-mALb)/urinary creatinine (U-Cr) integrated assay bigeminy strip, comprising a sample area and reaction areas. The U-mALb/U-Cr integrated assay bigeminy strip is characterized in that the sample area comprises a diffusion membrane and blood filtering membranes; the reaction areas comprise two detection windows, and the two detection windows can be used for detecting the ratios of the U-mALb and the U-Cr at the same time; the sample area for detecting the U-Cr by adopting a dry chemical method is arranged at the position where the reaction area is positioned, and the reaction area for detecting the U-mALb by using a colloidal gold dry type immune chromatography technology is arranged at a position which is 0.5cm away from the sample area. The different reaction areas contain different reagent pads, and the reagent pads respectively and independently react with corresponding components in urine. Synchronous detection can be realized only by dripping the random urine of a person to be tested into the sample area, so that the U-mALb/U-Cr integrated assay bigeminy strip is very suitable for medical institutions or individuals. By using the U-Cr for correction, the influence, caused by a sampling way and urine volume, on the excretory amount of urinary albumin can be eliminated, so that the U-mALb/U-Cr integrated assay bigeminy strip can provide more accurate evaluation for the albumin excretion rate and has a greater clinical significance for preventing diabetic nephropathy.

The invention aims to provide a novel use of penthorum chinense pursh and medicine or health care food prepared from the penthorum chinense pursh, and particularly relates to the novel use of the penthorum chinense pursh and the medicine or health care food prepared from the penthorum chinense pursh in the prevention and treatment of renal albuminuria. Tests show that the penthorum chinense purshhas an effect of reducing urinary proteins of nephropathy. According to the novel use, the application scope of the penthorum chinense pursh is enlarged, and a basis is provided for the clinical application of the penthorum chinense pursh in the prevention and treatment of the renal albuminuria.

The invention relates to a teabag for curing diabetes, which is prepared from 90 to 95 percent of Pu'er Tea and 5 to 10 percent of amino acid concentrated solution. Because the Pu'er tea of the product contains rich trace elements, the Pu'er Tea has positive action on the prevention and reduction of complication of diabetes together with the amino acid, thereby improving and controlling blood sugar and the blood pressure, adjusting the blood-fat and improving the albuminuria.

The invention discloses a Chinese medicinal combination for curing nephritis and edema and the application thereof, composed of Chinese Brake Herb, Jixuecao, Liquoricee Root, Persimmon Leaf, Membranous Milkvetch Root, Plantain Herb, etc. It is to be orally taken, convenient to use, tasting good and easy to be accepted by patients; has functions of nourishing liver and kidney, promoting blood circulation and rmoving blood stasis, and causing diuresis and detumescence, having advantages of good curative effect, short period of treatment, low price, no toxicity and side effect, convenient for patients to take, etc; and it is an ideal effective medicine for patients with acute and chronic nephritis and edema, hematuria, and albuminuria to select.

The invention discloses treating diabetic nephropathy and microalbuminuria with Chinese herbal medicine Salviae Miltiorrhizae Radix. Including boiling salvia miltiorrhiza to make a water-based extract, and then applying the extract to diabetics or microalbuminuric patients to treat diabetic nephropathy. In addition, it also includes the use of succinic acid inorganic salt extracted from Danshen to the sick body. The present invention also includes measuring the protein level in urine before, during and/or after administering the water-based extract or the inorganic salt of succinic acid to the patient.

The invention relates to the technical field of diabetic nephropathy, in particular to a medicine for treating and preventing diabetic nephropathy, which comprises 10 to 100 mg of tianagliflozin and 10 to 50 mg of DPP24 inhibitor. The medicine prepared by the invention can remarkably reduce the content or expression quantity of blood urea nitrogen, blood creatinine, 24h urine protein, urine protein quantification and transforming growth factor-beta1, remarkably improves the expression quantity of the klotho protein, has a better effect of treating and preventing diabetic nephropathy, can be stored for a long time, and has small toxic and side effects.

After a nephritis patient suffers from nephritis for several years, albumin in a little blood begins to leak into urine, at the moment, albumin leakage is easy to neglect because clinical symptoms arenot significant or the albumin is confused with other albuminuria caused by hypertension and hyperlipaemia, so that the illness state is worsened. But when it is found that other indexes reflecting renal functions, such as [beta]2 microglobulin, [alpha]1 microglobulin, transferrin and immunoglobulin are also obviously increased in urine, the situation confirms that the renal functions already have pathology changes. At present, no other effective methods exist except hormone on treatment, but long-term hormone treatment can cause many side reactions to the patient. If illness course freely develops, more albumin leaks into urine, and kidney damage can be further worsened. Cobra neurotoxin polypeptide molecules can effectively reduce leak of various albumin in urine, control and delay kidney pathologic progress, improve renal functions and have important significance in treatment of the nephritis through restraining autoimmunity inflammatory reactions of the kidney.

The invention discloses a new application of selepravastatin, namely an application of selepravastatin in preparation of a medicine for treating nephropathy. The application has the advantages that anew medicine for treating the nephropathy is provided, the effect of treating the membranous nephropathy is achieved through the immune effect, and finally animal experiments prove that the selaprivapeptide can reduce total urinary protein, urinary albumin and systolic pressure of membranous nephropathy model animals, so that the selaprivapeptide is a new immune agent and a novel therapeutic meansfor treating the membranous nephropathy.

The invention discloses a method for researching the relationship between HSD17B13 rs72613567 gene variation and renal function injury, and belongs to the technical field of medicine. According to the invention, a patient verified as NAFLD by biopsy is selected as an experimental population, the HSD17B13 genotype of the patient is detected, the glomerular filtration rate (eGFR), urine/serum NGAL and the ratio (u-ACR) of urine albumin to creatinine of the patient are measured, and finally, the relationship between the HSD17B13 rs72613567 genotype and gene variation and renal function damage is determined by multivariate regression analysis. Results show that the HSD17B13 rs72613567 A/- or A/A genotype is significantly related to a relatively low proteinuria risk, but is irrelevant to u-NGAL concentration or eGFR level, so that a novel insight is provided for early renal injury.

The invention discloses a traditional Chinese medicine composition. The traditional Chinese medicine composition contains crude drugs of radix dioscorea septemloba/dioscorea hypoglauca, ginseng, radixastragali, radix angelica sinensis, bighead atractylodes rhizomes, cinnamomum cassia bark, aconitum carmichaelii seminal root processed products, cornu cervi pantotrichum, alpinia oxyphylla fruits, lindera aggregata tubers, acorus tatarinowii reizomes and processed gizzard inner walls. The traditional Chinese medicine composition disclosed by the invention can strengthen the middle warmer, benefit qi, warm and recuperate kidney yang, promote urination and remove turbidity, and has favorable treatment effects on albuminuria, and symptoms of renal cell damage and high creatinine caused by nephropathy.

The present invention relates to a novel compound, to a composition comprising the same, to methods for preparing the compound, and the use of this compound in therapy. In particular, the present invention relates to a compound that is useful in the treatment and prevention of primary and secondary arterial hypertension, ictus, myocardial ischaemia, cardiac and renal insufficiency, myocardial infarction, peripheral vascular disease, diabetic proteinuria, Syndrome X and glaucoma.