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40 results about "Bridged compounds" patented technology
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A bridged compound is a chemical compound, generally an organic compound, but also possibly inorganic, that has two or more rings (a ring system) that contains a bridge—a single atom or an unbranched chain of atoms (or even just a valence bond) that connect two "bridgehead" atoms. The bridgehead atoms are defined as any atom that is not a hydrogen, and that is part of the skeletal framework of the molecule that is bonded to three or more other skeletal atoms. Clayden simplifies this description, saying that bridged bicyclic compounds "are just what the name implies—[molecules in which] a bridge of [an atom or of atoms] is thrown across from one side of the ring to the other," examples of which are shown at left and right, and below. The presence of the bridge connecting the bridgehead atoms, which are most often two non-adjacent atoms, distinguishes bridged compounds from fused ring compounds that have two rings linked by two adjacent atoms, and from spiro compounds that have two rings linked by a single atom.
Light adjustable lenses capable of post-fabrication power modification via multi-photon processes
InactiveUS7074840B2Unwanted changeSpectales/gogglesPhotosensitive materialsCalorescencePhotoinitiator
Owner:RXSIGHT INC
Light adjustable lenses capable of post-fabrication power modification via multi-photon processes
Owner:RXSIGHT INC
Light adjustable lenses capable of post-fabrication power modification via multi-photon processes
InactiveUS20050027031A1Unwanted changeSpectales/gogglesPhotosensitive materialsCalorescencePhotoinitiator
The invention relates to novel photoinitiators and their use in light adjustable compositions. The initiatives comprise two or more multiphoton chromophores linked by a bridging compound. The bridging compound consists of a material that is compatible with the base material of the light adjustable composition. The novel photoinitiator permit the readjustment of light adjustable material without the need for significant amounts of photoabsorbers.
Owner:RXSIGHT INC
Kit for detecting hepatitis c virus antibody as well as detection method and application thereof
ActiveCN104697988AHigh sensitivityStrong specificityChemiluminescene/bioluminescenceAntigenMicrosphere
The invention discloses a kit for detecting a hepatitis c virus antibody as well as a detection method and an application thereof, and belongs to the technical field of in vitro diagnosis and detection. The kit consists of the following components: (1) a magnetic microsphere system: including a magnetic microsphere and an HCV antigen in indirect connection by virtue of a first bridged compound; and (2) a marker system: including an HCV fusion antigen and a marking tracer which are in indirect connection by virtue of a second bridged compound, wherein the HCV antigen and the HCV fusion antigen are combined with an HCV antibody on different sites. The kit and the detection method, by detecting the hepatitis c virus antibody through chemiluminescence immunoassay, have the advantages of high sensitivity, good specificity and broad detection scope.
Owner:SHENZHEN NEW INDS BIOMEDICAL ENG
Derivatized expanded starch for odor control
An absorbent article includes a plurality of derivatized expanded starch particles to control odor. The derivatized expanded starch particles include an expanded starch particle base and at least one transition metal chemically bonded to the expanded starch particle base. The transition metal is coordinatively bonded to a bridging compound and the bridging compound is covalently bonded or physically absorbed to a surface of the expanded starch particle bases.
Owner:KIMBERLY-CLARK WORLDWIDE INC
Light adjustable lenses capable of post-fabrication power modification via multi-photon processes
The invention relates to novel photoinitiators and their use in light adjustable compositions. The initiatives comprise two or more multiphoton chromophores linked by a bridging compound. The bridging compound consists of a material that is compatible with the base material of the light adjustable composition. The novel photoinitiator permit the readjustment of light adjustable material without the need for significant amounts of photoabsorbers.
Owner:RXSIGHT INC
Sulfonyl diphenylethyllene endocompound and its preparation method and pharmaceutical uses
InactiveCN1762994AGood anti-inflammatory activityGood inhibitory effectOrganic chemistryAntipyreticEpoxyCyclo oxygenase 2
The present invention relates to vinyl bridge compound containing sulfonyl radical and diphenyl radical and in the general expression as shown. The present invention also relates to its preparation process and application in preparing medicine for inhibiting epoxy synthase 2 and medicine for treating inflammation and pain of mammal.
Owner:SHANDONG UNIV
Kit for detecting treponema pallidum antibody as well as detection method and application thereof
ActiveCN104698185AAdequate binding reactionHigh detection sensitivityBiological testingAntigenMicrosphere
The invention discloses a kit for detecting a treponema pallidum antibody as well as a detection method and an application thereof, and belongs to the technical field of in vitro diagnosis and detection. The kit consists of the following components: (1) a marker system: including a treponema pallidum recombinant antigen 1 in direct or indirect connection to a marking tracer, or staphylococcus aureus A protein in direct or indirect connection to the marking tracker; (2) a bridged compound system: including a treponema pallidum recombinant antigen 2 in direct or indirect connection to a first bridged compound; and (3) a magnetic microsphere system: comprising a magnetic microsphere in direct or indirect connection to a second bridged compound, wherein the first bridged compound is combined with the second bridged compound. The kit and the detection method disclosed by the invention can promote the full implementation of conjugation reaction between antigen and antibody; and detection sensitivity can be improved.
Owner:SHENZHEN NEW INDS BIOMEDICAL ENG
Reaction resin composition and use thereof
ActiveUS20150232719A1Good suitExclude influenceEster polymer adhesivesEpoxy resin adhesivesDouble bondBridged compounds
A reaction resin composition that can be used for the chemical fastening of anchoring means in boreholes and for construction gluing is described. The composition includes (A) a resin component, which contains at least one radically hardenable compound and at least one epoxy resin, which contains, on average, more than one epoxy group per molecule, and a (B) hardener component, which contains a hardening agent for at least one radical compound and at least one amine. The radically hardenable compound and hardening agent in each case being reaction-inhibiting spatially separated from one another. In an embodiment the composition contains no Cu—, Mn—, and iron compound, and no bridging compound. The ratio of double bond value to epoxy value nDB:nEP in the resin component is between 0.01 and 0.55 or between 5 and 50.
Owner:HILTI AG
Phenyl-bridged compound with triarylamine and ferrocene end groups, method for preparing phenyl-bridged compound and application thereof
The invention discloses a phenyl-bridged compound with triarylamine and ferrocene end groups, a method for preparing the phenyl-bridged compound and application thereof, and relates to the technical field of photoelectric materials. A structural formula of the phenyl-bridged compound with the triarylamine and ferrocene end groups is shown. An R in the structural formula represents H or CH3 or OCH3; intermediate benzene ring joints are positioned at meta-positions or para-positions of respective benzene rings. The phenyl-bridged compound with the triarylamine and ferrocene end groups, the method and the application have the advantages that the phenyl-bridged compound is of a novel molecular structure, strong electron interaction between the end groups of the phenyl-bridged compound is discovered via tests by the aid of electrochemical processes, accordingly, novel molecular conducting wire materials can be developed on the basis of the phenyl-bridged compound, and a novel way for designing and synthesizing novel molecular conducting wires in follow-up procedures can be developed by the phenyl-bridged compound with the novel structure.
Owner:HENGYANG NORMAL UNIV
Method for synthesizing 2-bromo-1,1,2,2-tetrafluoroethyl substituted aryl building block
ActiveCN107445795ARapid responseSource GreenSilicon organic compoundsAmino preparation from aminesIridiumAniline
The invention discloses a method for synthesizing a 2-bromo-1,1,2,2-tetrafluoroethyl substituted aryl building block under simple conditions. The method comprises the following steps: based on aniline and 1,2-dibromotetrafluoroethane compounds, by taking a complex taking iridium, ruthenium and other transition metals as a core as a catalyst, preparing various aniline structures substituted by bromotetrafluoroethane at high efficiency, and further performing derivatization on amino, thereby obtaining multiple 2-bromo-1,1,2,2-tetrafluoroethyl aromatic hydrocarbon compounds. The method takes cheap and readily available aniline and derivatives thereof and the dibromotetrafluoroethane as raw materials, and has the advantages of being small in catalyst amount, wide in substrate application range, easy and convenient to operate, high in reaction efficiency and the like, and after the reaction is ended, another bromine atom is well remained. Meanwhile, the products can be easily converted into 1,1,2,2-tetrafluoroethyl bridged compounds, and have very wide and important purposes in the fields of pesticides, liquid crystal materials, molecular imaging and the like.
Owner:ZUNYI MEDICAL UNIVERSITY
Method for preparing Zidovudine azide intermediate by phase transition method
ActiveCN101190934AMild operating conditionsShort reaction timeSugar derivativesCombinatorial chemistrySodium azide
The invention discloses a method which adopts a phase transfer method to prepare Zidovudine azide intermediate, comprising the following steps: Zidovudine oxy-bridged compound reacts with sodium azide in the solution, in which a phase transfer catalyst and a phase transfer ancillary reagent exist, and then the Zidovudine azide intermediate is collected from the reaction product. The method of the invention has moderate operational conditions, short reaction time and a reaction yield of 91 percent, thereby increasing production hidden dangers greatly.
Owner:SHANGHAI DESANO CHEM PHARMA +1
Process for preparing cyclopentadienyl compounds
InactiveUS6162937AImprove economyLow yieldSilicon organic compoundsOrganic compound preparationAlpha-olefinSolvent
A process for preparing bis-cyclopentadienyl compounds bridged by a methylene group is reported, said process comprising reacting formaldehyde with a cyclopentadienyl compound in the presence of a base and of a solvent having a dielectric constant ( epsilon ), measured at 25 DEG C., higher than 7. The bridged compounds, obtainable in high yields with this simple single-step process, can be used to prepare ansa-metallocenes, active as catalyst components in the polymerization of olefins.
Owner:MONTELL TECH CO BV
Novel liquid crystal medium containing deuterated difluoromethoxy-bridge compound and application thereof
InactiveCN104560060ALiquid crystal compositionsOrganic chemistryCharge retentionDielectric anisotropy
The invention discloses a liquid crystal medium and application of the liquid crystal medium in liquid crystal display. The liquid crystal medium has various isomerisms of positive dielectric and is characterized by containing one or more compound shown by a structural formula I. The liquid crystal medium is excellent in performance, wide in nematic temperature range, suitable in anisotropy of refractive index, high in charge retention, low in rotary sticky degree and energy consumption and excellent in response speed and high and low temperature performances. The liquid crystal medium containing a liquid crystal monomer is relatively stable in variations of the rotary sticky degree, a K value and the dielectric anisotropy during low temperature and is obviously excellent in the performances compared with a liquid crystal medium formed by liquid crystal monomers in other types during low temperature. In the liquid crystal display, the composition has wide application prospect and application value and is particularly suitable for an active matrix TN-TFT, IPS-TFT, FFS-TFT display with rapidness in response.
Owner:SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO LTD
Bridge compound pier stud structure based on orientation ECC and construction process
ActiveCN109338874AImprove cracking performanceImprove seismic performanceBridge structural detailsBridge erection/assemblyReinforced concrete columnRebar
The invention discloses a bridge compound pier stud structure based on an orientation ECC and a construction process. The bridge compound pier stud structure comprises a pier stud plastic hinging areafor connecting a concrete pier stud base and a concrete pier stud. The pier stud plastic hinging area is of a reinforced concrete columnar structure. Concrete adopted in the pier stud plastic hingingarea is an oriented-fiber-enhanced cement-base composite. The oriented-fiber-enhanced cement-base composite is a cement-base composite with fibers in a cement base body arrayed in one direction. Thetending direction of the fibers in the oriented-fiber-enhanced cement-base composite is the same as the axial direction of the pier stud plastic hinging area. A reinforcing steel bar framework adoptedin the pier stud plastic hinging area is formed by binding a plurality of low-yield reinforcing steel bars and a plurality of high-strength reinforcing steel bars through reinforcement stirrups. Thelow-yield reinforcing steel bars and the high-strength reinforcing steel bars are parallel in pairs and located in different planes.
Owner:SHANDONG UNIV
Iridium complex-containing phosphor material as well as preparation and application in beryllium ion detection
ActiveCN108084231AQuick responseHigh sensitivityIndium organic compoundsFluorescence/phosphorescenceIridiumAnti jamming
The invention discloses an iridium complex-containing phosphor material as well as preparation and application in beryllium ion detection, belongs to the technical field of photoelectric phosphor materials, and solves the problem in the prior art that the anti-jamming capability of a fluorescent probe for detecting beryllium ions is weaker. The preparation method of the iridium complex-containingphosphor material is characterized by enabling 9-metallacrown-3 to react with 3,4-dihydroxy benzaldehyde, thus obtaining a 9-metallacrown-3 derivative; then synthesizing a dichloro-bridged compound ofiridium on the basis of the 9-metallacrown-3 derivative; then enabling the dichloro-bridged compound of the iridium to interact with a corresponding auxiliary ligand, thus preparing an iridium complex-based phosphor chemical sensor. The iridium complex-containing phosphor material comprises two structural formulas which can be respectively applied to beryllium ion detection in an ionic type solution and a neutral solution; compared with a traditional fluorescent sensor, the iridium complex-based phosphor chemical sensor has larger stokes displacement and longer emission lifetime; meanwhile, the iridium complex-based phosphor chemical sensor has strong anti-jamming capability on multiple metal cations.
Owner:ANHUI UNIVERSITY OF TECHNOLOGY
Zika virus E protein conjugate vaccine and preparation method thereof
ActiveCN111514286AInnovativeOriginalSsRNA viruses positive-senseViral antigen ingredientsZika virusChemical compound
The invention discloses a Zika virus E protein conjugate vaccine and a preparation method thereof. The preparation method comprises the following specific steps of: 1) oxidizing an ortho-position hydroxyl group of [beta]-glucan into an aldehyde group, so as to obtain oxidized [beta]-glucan; 2) adding a connecting bridge compound, enabling the connecting bridge compound to react with the aldehyde group in the oxidized [beta]-glucan to obtain [beta]-glucan containing a connecting bridge; and 3) enabling Zika virus E protein to react with the [beta]-glucan containing the connecting bridge, and carrying out purification to obtain the Zika virus E protein conjugate vaccine. The vaccine can be induced to generate a high-level cellullar immunologic response and a body fluid immunologic response.
Owner:INST OF PROCESS ENG CHINESE ACAD OF SCI
Reaction resin composition and use thereof
ActiveUS9580633B2Good flexibilityPrevent curingEster polymer adhesivesEpoxy resin adhesivesEpoxyChemical compound
Owner:HILTI AG
Amido metal iridium complex electrophosphorescent luminescent material adopting phenylpyrazole main ligand and preparation thereof
InactiveCN101633841AStrong phosphorescent propertiesEasy to synthesizeGroup 8/9/10/18 element organic compoundsLuminescent compositionsIridiumAniline
The invention relates to an amido metal iridium complex electrophosphorescent luminescent material adopting phenylpyrazole as main ligand and a preparation thereof, belonging to the technical field of electrofluorescence. The electrophosphorescent luminescent material is an amido metal iridium complex adopting the phenylpyrazole as main ligand, the molecular structure is (C^N)2Ir(ayl), wherein, (C^N) is bidentate ligand containing 1-phenylpyrazole structure, and ayl is bidentate ligand containing amide structure. The preparation method comprises the following steps : firstly, using aniline or aniline derivative and anhydride or acyl chloride to heat and backflow in acetic acid so as to obtain amide, then carrying out reaction by using the obtained amide and dichloro-bridge compound (C^N)2Ir(mu-Cl)2Ir(C^N)2 as the derivative of 1-phenylpyrazole (C^N) in ethylene glycol under the existence of sodium alcoholate, and obtaining the target product (C^N)2Ir(ayl) of electrophosphorescent luminescent material of bidentate ligand containing 1-phenylpyrazole structure. The synthetized metal iridium complex has stronger luminescent performance of phosphorescence and can be used as a functional material in an organic electrophosphorescent device.
Owner:JIANGNAN UNIV
Reactive resin composition and use thereof
A reactive resin composition is described, comprising a resin constituent (A) comprising a free-radically polymerizable compound (a-1), a compound (a-2) which can react with an amine, and a bridging compound (a-3) having at least two reactive functionalities, one of which can be free-radically (co)polymerize and one of which can be react with an amine, and a hardener constitute (H) comprising at least one dialkyl peroxide (h-1) and at least one amine (h-2) where the resin constituent (A) and the hardener (H) or the resin constituent (A) and at least one dialkyl peroxide (h-1) and at least one amine (h-2) of the hardener (H) are spatially separated from one another, in order to prevent reaction prior to mixing of these components, which is characterized in that the hardener constituent (H) further comprises an accelerator mixture (B) consisting of a copper compound (b-1) and a 1,3-dicarbonyl compound (b-2), with the proviso that the resin composition is suitable for use for construction purposes, preferably for securing anchor thread bars, iron reinforcements, bushing or screws in boreholes in all kinds of substrata.
Owner:HILTI AG
Bridge compound with N, N-dialkylamino group and application thereof
InactiveUS20090054645A1Easy to fixEasy constructionOrganic chemistryReactive dyesUv absorberPhotochemistry
The present invention relates to a bridge compound with N,N-dialkylamino group, represented by the following formula (I),wherein, R, R′, R″, R1, R2, B, B′, i, j, m, and n are defined the same as the specification. The novel bridge compound of the present invention is suitable for being used as a bridge group between dyestuffs, ultraviolet absorbers, or one dyestuff and one ultraviolet absorber. In addition, the present invention further provides a dyestuff compound provided from the aforementioned bridge compound.
Owner:EVERLIGHT USA INC
Kit for detecting hepatitis C virus antibody, detection method and application thereof
ActiveCN104697988BHigh sensitivityStrong specificityChemiluminescene/bioluminescenceAntigenMicrosphere
Owner:SHENZHEN NEW INDS BIOMEDICAL ENG
Synthesis method of organic compound of diamine monoselenide
InactiveCN106977438ALow costThe preparation operation is simple and easy to controlCarbamic acid derivatives preparationOrganic compound preparationSynthesis methodsOrganic compound
The invention discloses a synthesis method of an organic compound of diamine monoselenide, and relates to a synthesis method of a compound, the method comprises the following steps: 1) protection of ethylethanolamine, to be more specific, using di-tert-butyl dicarbonate for protection of the ethylethanolamine; 2) hydroxy acylation, to be more specific, using one or a mixture of two of paratoluensulfonyl chloride and Phthaloyl dichloride as a hydroxyacylating agent; 3) reaction with sodium hydrogen selenide to obtain a single selenium bridged compound, and deprotection; and 4) extraction with an organic solvent to obtain the diamine monoselenide. A diamine monoselenium compound with protective group BOC is prepared from the ethylethanolamine as a raw material by (BOC) 2O protection, hydroxyl sulfonation reaction and reaction with the sodium hydrogen selenide by the method, and finally the diamine monoselenide compound can be obtained by treating with trifluoroacetic acid. The method has the advantages of low raw material cost, easy obtaining, simple preparation, easy control, high yield and high scientific research value.
Owner:SHENYANG INSTITUTE OF CHEMICAL TECHNOLOGY
Bridged Bis(Alkoxysilane) or Silsesquioxane Compound Having Benzoxazine-Containing Group
ActiveUS20130053529A1Low dielectric constantHigh mechanical strengthSilicon organic compoundsCross-linkNMR - Nuclear magnetic resonance
A benzoxazine-bridged compound is provided. The compound has a low dielectric constant, a high mechanic strength and a high glass transition temperature. The compound has a highly cross-linked structure with a yellow-light photoluminescent emission. Characterization of the present disclosure has been conducted with Fourier transform infrared, nuclear magnetic resonance, molecular mass and elemental analysis.
Owner:NAT CHUNG SHAN INST SCI & TECH
Bridge compound with N,N-dialkylamino group and application thereof
InactiveUS7683208B2Easy to fixEasy constructionOrganic chemistryReactive dyesUv absorberPhotochemistry
Owner:EVERLIGHT USA INC
3-trifluoromethyl-2,5-diazabicyclo[2.2.1] heptane derivant and preparation method thereof
InactiveCN102167702AChange solubilityAlter biological metabolic stabilityOrganic chemistryBulk chemical productionSolubilitySide chain
The invention discloses a 3-trifluoromethyl-2,5-diazabicyclo[2.2.1] heptane derivant and a preparation method thereof, mainly aiming to solve the technical problems that bridged compounds with structure of 2,5-diazabicyclo[2.2.1] heptane are restrained in extension of a space structure, and the compounds have poor water solubility. The chemical structural formula is as follows in the specification, wherein X is NR1 or O, R1 is a functional group or amino-substituted protective group, and is selected from one of H, C1-10 linear-chain or substituent-side-chain-containing alkyl, benzyl, 2,4-dimethoxybenzyl, 4-methoxybenzyl, tertiarybutoxy carbonyl, carboxybenzyl, alkylacyl, aroyl, alkylsulfonyl or aryl sulfonyl, and R2 is a functional group or amino-substituted protective group, and is selected from one of H, C1-10 linear-chain or substituent-side-chain-containing alkyl, benzyl, 2,4-dimethoxybenzyl, 4-methoxybenzyl, carboxybenzyl, alkylacyl, aroyl, alkylsulfonyl or aryl sulfonyl.
![3-trifluoromethyl-2,5-diazabicyclo[2.2.1] heptane derivant and preparation method thereof](https://images-eureka.patsnap.com/patent_img/2547f914-1758-41be-bd07-a8060bdb397e/FSA00000037763800011.png "3-trifluoromethyl-2,5-diazabicyclo[2.2.1] heptane derivant and preparation method thereof")
![3-trifluoromethyl-2,5-diazabicyclo[2.2.1] heptane derivant and preparation method thereof](https://images-eureka.patsnap.com/patent_img/2547f914-1758-41be-bd07-a8060bdb397e/FSA00000037763800012.png "3-trifluoromethyl-2,5-diazabicyclo[2.2.1] heptane derivant and preparation method thereof")
![3-trifluoromethyl-2,5-diazabicyclo[2.2.1] heptane derivant and preparation method thereof](https://images-eureka.patsnap.com/patent_img/2547f914-1758-41be-bd07-a8060bdb397e/FSA00000037763800021.png "3-trifluoromethyl-2,5-diazabicyclo[2.2.1] heptane derivant and preparation method thereof")
Owner:上海药明康德新药开发有限公司
Preparation method of zidovudine and intermediate thereof
InactiveCN104844672AHigh recovery rateRaw materials are easy to getSugar derivativesSugar derivatives preparationDistillationFiltration
The invention discloses a preparation method of zidovudine and an intermediate thereof. The intermediate is a zidovudine azide compound. The method comprises the steps of: (1) a dissolution reaction: dissolving a zidovudine oxygen bridge compound in an organic solvent, adding an azidation reagent and a catalyst inorganic acid salt or a small molecular organic acid salt, and reacting and insulating at 90-115 DEG C for 12-48 h; (2) distilling filtration: cooling, filtering, conducting reduced pressure distillation on the filtrate and recovering an organic solvent; and (3) extraction concentration: extracting and washing the above obtained product and concentrating to obtain the zidovudine azide compound. Compared with the prior art, the whole process has the advantages of easily available raw materials, low cost, environment friendliness, and high recovery rate of solvent. The preparation process of the intermediate zidovudine azide compound uses inorganic acid salt and small molecular organic acid catalytic reaction, effectively reduces the azidation reaction temperature, shortens the reaction time, and is conducive to process production. The obtained product has less impurities, good state; and the zidovudine crude refining process is simple, and high in yield.
Owner:XENOAH PHARMA INC
Amido metal iridium complex electrophosphorescent luminescent material adopting phenylpyrazole main ligand and preparation thereof
InactiveCN101633841BStrong phosphorescent propertiesEasy to synthesizeGroup 8/9/10/18 element organic compoundsLuminescent compositionsIridiumAniline
Owner:JIANGNAN UNIV
Kit for detecting Treponema pallidum antibody, detection method and application thereof
ActiveCN104698185BAdequate binding reactionHigh detection sensitivityBiological testingAntigenSpiroplasma
Owner:SHENZHEN NEW INDS BIOMEDICAL ENG
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