84 results about "Follow up studies" patented technology

The invention discloses a true triaxial multi-field multi-phase coupling dynamic test system and method. One end of an incident rod and one end of a transmission rod are fixed to the two ends of a triaxial loading device respectively; the triaxial loading device is a hexahedron, comprises three pressure device sets opposite to each other in pairs and is capable of separately controlling over compression and unloading of all faces of rock samples and changing the prestress loading value of six oil cylinders freely, both the incident rod and the transmission rod are provided with strain gages beneficial for measuring mechanical property of the rock samples when the rock samples are impacted; furthermore, a temperature effect test system and a chemical effect test system are additionally arranged, the temperature field and chemical field where the rock samples are located are changed by adjusting the temperature of the system and injecting different chemical solvents and various gas, meanwhile, the stress field borne by the rock samples is combined, the mechanical characteristics of the rock samples under the multi-field multi-phase coupling action of the stress field, the temperature field, the chemical field, solid, liquid, gas and the like, and data and theoretical supports are provided for follow-up studies.

The invention discloses a protection configuration method for a typical multi-terminal flexible direct current power distribution system. The typical multi-terminal flexible direct current power distribution system is divided into an alternating current system protection region, a main converter protection region, a direct current line protection region and an access converter protection region; and a protection scheme is configured for each protection sub-region by combining the operating requirements of the direct current power distribution system and the factors of fault and electrical characteristics and the like on the basis of division of the protection regions. The scheme can comprise different protection algorithms, which can protect the safety of equipment in the region, and simultaneously can be used as backup protections of other regions. Configuration of protection devices is to determine the installation positions and the number of the protection devices, employing simplicity, convenience and reliability as principles. According to the method, the fault position in the direct current power distribution system can be quickly and reliably judged; fault removal and isolation are achieved; stable operation of the multi-terminal flexible direct current power distribution system can be ensured; and the protection configuration method has certain guiding significance in follow-up study of the protection system.

The invention discloses an archaeological excavation unit sequence three-dimensional visualization method based on multi-view images and laser scanning. The method comprises the following steps: 1) obtaining holographic data of each archaeological site excavation unit at different periods by utilizing a three-dimensional laser scanner in periods; 2) obtaining multi-view image data of stratum, historical remains and traces of each archaeological site excavation unit at different periods; 3) carrying out 3D modeling by utilizing three-dimension scanning data and the multi-view image data under the basis of data correction and matching; and 4) carrying out multi-source data fusion on a three-dimensional model established based on the three-dimension scanning data and the multi-view image data in periods, and realizing archaeological site excavation unit sequence three-dimensional visualization. The method not only provides precise space attributes for conversion and contrast for archaeological excavation and follow-up study thereof, but also provides scientific and accurate recording mode and visual display effect for the archaeological site excavation process.

The invention discloses a method and a device for detecting and selecting laser-induce enhanced Raman spectrum in a liquid. The method comprises the following steps of: focusing the inducing light on a suspending to-be-detected sample and forming a three-dimensional light well in liquid; enriching metal nanoparticles on the surface of the to-be-detected sample; and coinciding the focuses of exciting light and inducing light, thereby forming a laser-induce enhanced Raman signal. The realizing method disclosed by the invention is simple and convenient, is obvious in spectrum enhancing effect and is fit for quick detection for in-situ Raman spectrum of a biological sample under a liquid environment; the to-be-detected sample and the metal nanoparticles are hatched together; the method is especially fit for the field of quick detection for diseases, epidemic situation, food safety, and the like; the toxic damage to the biological sample caused by the metal nanoparticles is greatly reduced, so that the true physiological status of living cell can be extremely reflected; the optical tweezers formed according to the method provided by the invention can be used for sorting, extracting and eluting, can realize the function of identifying and sorting Raman spectrum of a single living cell, and is beneficial to the follow-up study on the biological sample.

The invention relates to an object classification-oriented rare earth mining area remote sensing information extraction method. An object classification-oriented method is adopted to extract rare earth mining area remote sensing information; comparative analysis is performed on the extraction result of the object classification-oriented method and the extraction result of a traditional supervision classification method; and the feasibility and advantages of the object-oriented classification method in rare earth mine information extraction are discussed, and a foundation is laid for the follow-up study of the present situation investigation, dynamic monitoring of rare earth and the like. The method comprises the following steps that: 1) the remote sensing data source of a selected study area is preprocessed, and an edge-based segmentation algorithm is adopted to perform image segmentation; 2) a series of rules is established based on terrain information, spectral information and geometric information, and feature extraction is realized; and 3) object-oriented classification is performed, and the rare earth mining area of the study area is extracted.

The invention discloses a human body target and surrounding structure compatibility detecting method based on a UWB (Ultra Wideband) bio-radar, comprising the following steps: a preprocessing step A, a human body target detecting step B and a structure detecting step C. Since most of survivors pressed and buried in ruins after an earthquake and other disasters are buried in holes formed under the ruins is considered, a certain space is formed between the survivors and the ruins, and the medium in the space is air. The detection and identification are realized on the upper and lower interfaces of the holes according to the limited conditions and the human body target position information, so that more accurate and more comprehensive ruins structure information can be obtained in the follow-up study, and new thinking can be provided for the application and development of a UWB search and rescue bio-radar technology.

The invention discloses an adhesion property testing device for clammy materials and an adhesion property testing method for the clammy materials, which are mainly used for the field of testing adhesion properties of agricultural materials to solve the problem that a traditional adhesion property testing device and a traditional adhesion property testing method are inadaptable to testing the adhesion properties of the agricultural materials. The adhesion property testing device comprises a loading time-keeping device, a computer and an image acquisition system. The testing method based on the adhesion property testing device includes: acquiring images of adhesive materials on the surface of an adhesive plate and performing feature extraction and binarization processing for the images; sequentially computing the number of feature pixels, the actual area of remaining adhesive materials and adhesion rate defined by the adhesion property testing deviceto accordingly obtain the adhesion properties of the clammy materials. The novel testing method is provided for follow-up study based on the adhesion properties of the agricultural materials, and can be used for solving the problem that the traditional adhesion property testing method is inadaptable to testing the adhesion properties of the agricultural materials.

The invention relates to a test method for studying rock joint surface morphology evolution in a whole shear process. The method includes: using an artificial rock material to copy a rock joint surface to obtain multiple groups of joint samples with completely identical surface morphology, scanning all the joint samples before testing to obtain joint surface initial morphology data; conducting a group of joint shear test to obtain a complete joint shear displacement-shear stress test curve; in the follow-up study process, selecting shear displacements corresponding to different joint shear stress states, and performing multiple groups of joint shear test, stopping each group of test at different shear displacement positions, then scanning the joint surface morphology data obtained by the groups of test, and performing comparison with the morphology data of each sample before test so as to obtain morphology evolution data in the joint shear process. Compared with the prior art, the method provided by the invention has the advantages of simplicity and convenience, more accurate and reliable test result, good repeatability and wide application range, thus having very good application prospect.

A method for studying muscle fatigue on the basis of static myoelectricity after electrical stimulation includes respectively acquiring static surface myoelectric signals of each subject: selecting the subjects, arranging experimental periods, placing surface myoelectric electrodes and stimulating electrodes on the subjects, and acquiring the static surface myoelectric signals; and respectively analyzing power spectrums of the acquired static surface myoelectric signals: computing the acquired static surface myoelectric signals by a periodic diagram process to acquire the power spectrums, drawing frequency spectrograms according to the power spectrums, computing median frequencies and analyzing the median frequencies. The method has the advantages that change of the surface myoelectric signals after electrical stimulation can be represented, myoelectric response caused by electrical stimulation can be comprehensively evaluated in a frequency domain, an experimental basis is provided for follow-up study, accordingly, an idea is provided for technical standards for evaluating effects of electrical stimulation on human bodies, and development of electrical stimulation is promoted.

The invention discloses an emotional recognition research method based on an electroencephalogram signal of dual-tree complex wavelet. Decomposition and reconstitution of dual-tree complex wavelet transform are adopted to calculate phase information and sample entropy value of different wavebands of the electroencephalogram signal, and the two features serve as feature vectors of different emotions to be input into an SVM classifier, so that three emotions of calmness, pleasure and sadness are recognized effectively. The results show that the defect that discrete wavelet transform is poor in aliasing resistance and high in translation sensitivity is overcome through dual-tree complex wavelet transform, the extracted feature vectors has a good classifying recognition result, and new thoughts are provided for later researching of emotional recognition of the electroencephalogram signal.

The invention discloses an unsupervised cluster characteristic selection method based on Laplace regularization. The unsupervised cluster characteristic selection method comprises the following steps: (1) constructing a sample characteristic matrix, (2) calculating a Laplace matrix, and (3) extracting the characteristics of the sample characteristic matrix. The unsupervised cluster characteristic selection method disclosed by the invention selects the characteristics through directly measuring the variance of follow-up study prediction results, and can directly enhance the follow-up study prediction results. Influence of the selected characteristics to predicted values of the study problems is taken into the consideration in the characteristic extraction process, so that the follow-up study efficiency can be efficiently improved. In addition, the modeling of data of the unsupervised cluster characteristic selection method disclosed by the invention is on the basis of a Laplace method of manifold geometry of the data. The unsupervised cluster characteristic selection method can efficiently reflect distribution information of the data in the space so as to calculate the maximum dimensionality of the information amount.

The invention discloses an enriched enrichment and separation method of escherichia coli O157 (E.colio157), provides a basis for the follow-up study of target bacteria, and relates to the field of biotechnology. The method comprises the following steps of: carrying out covalent coupling on a broom molecule and an E.coli O157 antibody, enveloping a long chain biotin molecule by using the antibody modified broom molecule, capturing the target bacteria in a sample solution by using the broom molecule co-modified by the antibody and the long chain biotin, recognizing and coupling the long chain biotin modified broom molecule in the sample solution by a streptavidin modified nanometer magnetic bead, and subjecting the captured bacteria to separation and heavy suspension and the like, wherein a heavy suspension solution can be directly subjected to subsequent analysis. Compared with a traditional bacteria magnetic separation method, the method disclosed by the invention is more applicable to magnetically separating the bacteria in a complex matrix, and the separation efficiency of the target bacteria in the sample is improved.

The invention discloses an experimental method for evolution simulation of a high-temperature and overpressure reservoir, and belongs to the technical field of high-temperature and overpressure reservoirs; an artificial core is the basis of a mechanical compaction experiment and a water-rock simulation experiment, whether the ratio scheme of the artificial core is reasonable or not is of great significance to follow-up studies, according to the actual rock type of the high-temperature and overpressure reservoir and clastic rock samples of which the sandstone grain sizes are artificially proportioned, the specific ratio scheme comprises the following steps that the relative percentage contents of skeleton clastic particles and clastic clay of different horizons and different tectonic divisions are counted according to the content of clastic components in a study area; the content of authigenic minerals in the proportioning process is not considered to restore the appearance of the clastic particles while depositing; the difficulty of the proportioning process lies in the distinction between the content of clastic clay minerals and the content of authigenic clay minerals. On the basis of the artificially proportioned rock samples, the mechanical compaction experiment and the water-rock simulation experiment are used to explore the effect of high temperature and overpressure on reservoir evolution and main control factors of a high-quality reservoir so as to guide favorable lithologic trap evaluation and later exploration and development of oil and gas to lower the cost.

The invention belongs to the field of molecular biology and microbial fermentation, and provides a Surfactin and Plipastatin co-production bacillus subtilis strain pB2-L, a method for constructing the same and application of the Surfactin and Plipastatin co-production bacillus subtilis strain. The method for constructing the Surfactin and Plipastatin co-production bacillus subtilis strain includes steps of amplifying target genes; amplifying fusion fragments; acquiring intermediate vectors; acquiring recombinant integration plasmids; acquiring and detecting transformants. The Surfactin and Plipastatin co-production bacillus subtilis strain, the method and the application have the advantages that a fragment of fusion genes P43-sfp-degQ are led into amyE site of B-subtilis pB2 of non-producing antibacterial substances Surfactin and Plipastatin by the aid of homologous recombination processes, so that the recombinant Surfactin and Plipastatin co-production bacillus subtilis strain B.subtilis pB2-L can be obtained, the strain has certain antibacterial activity for gram positive bacteria and filamentous fungi, and the Surfactin and Plipastatin co-production bacillus subtilis strain, the method and the application have an important significance on follow-up study.

The invention discloses a simulating test method of CH4 layered displacement by CO2 in a multi-layer superposed gas-containing system. The simulating test method comprises the following steps of preparing tests, loading stress, adsorbing gas, displacing methane, and completing the primary test and the other tests in the same group. Permeable plates of the inner bottom of a test-piece box adopted by the tests are arranged in a sectionalized mode, and an airflow passageway is formed below each permeable plate. When moulded coal is formed, coal layers in the test-piece box corresponds to the permeable plates one to one, and similar materials are arranged between the coal layers in a spaced mode so as to simulate a rock layer. An extracting branch pipe with the direction contrary to the Y-direction pressure is buried in each coal layer. Therefore, the simulating test method of CH4 layered displacement by the CO2 in a horizontal well of the multi-layer superposed gas-containing system lays the foundation for follow-up study of CH4 displacement by the CO2 in the horizontal well of the multi-layer superposed gas-containing system.

The invention discloses an electric power information physical fusion system effect relationship sorting method considering running topology characteristics. The method comprises the following steps that 1, a complex network model is built for an electrical network information physical fusion system; 2, an information layer node importance comprehensive evaluation matrix is defined, wherein importance reference indexes are the number of degrees of nodes, betweenness, the shortest distance with control center nodes and clustering indexes; 3, a physical node load is gotten; 4, on the basis of the interactive relationship, the information layer node importance comprehensive evaluation matrix serves as a weight, and a physical layer node weighted node load corresponding to the weight is calculated; 5, according to the physical layer node weighted node load result obtained in the step 4, physical layer nodes are sorted, and the sorted result is equivalent to importance sorting of the interactive relationship corresponding to the physical nodes. Accordingly, help is provided for a follow-up study and actual electric power information physical fusion system running control management.

Occasionally relevant findings and important recommendations made within medical or radiology reports fail to elicit the appropriate follow-up due to multiple factors. The clinician may miss the recommendation or lose track of it while addressing a more acute illness, the recommendation may have not been conveyed to the patient, or the patient may fail to schedule or show-up for the subsequent exam. Prior literature indicates that a significant percentage of scheduled appointments result in no-shows or cancellations by patients, and a small but significant percentage of indicated follow-up studies are thus not obtained. Such omissions occasionally result in adverse consequences suffered by the patients, and increase the risk of legal liabilities to the clinicians or radiologists. A method and system is presented that identifies patients who did not obtain such recommended diagnostic tests or therapeutic interventions, and which sorts and filters the detected patients according to relevance of the recommendation, optionally discarding recommendations of low relevance, and facilitates the management of the detected patients.

The invention discloses an experiment device for simulating real scattering behaviors of tyre wear particles. The experiment device is characterized in that the experiment device comprises a support, a tyre, a rotation wheel and a wind-outlet device. The tyre and the rotation wheel are coupled to the support; the rotation wheel is arranged right under the tyre; the support is fixedly provided with a horizontal plate for simulating a road surface; the horizontal plate is arranged between the tyre and the rotation wheel; the horizontal plate is provided with a groove; the outer circumference surface of the rotation wheel passes through the groove and is abutted against the outer circumference surface of the tyre; the friction coefficient of the outer circumference surface of the rotation wheel is equal to or similar to the friction coefficient of a real road surface; the support is fixedly provided with a wheel cover for simulating an automobile tire splash guard; the wheel cover covers the tyre; the support is provided with a tyre rotation driving device and a rotation wheel rotation driving device; and the wind-outlet device is arranged in front of the tyre. The experiment device has the advantages that the experiment device can simulate real scattering behaviors of the tyre wear particles very well, thereby facilitating to develop a follow-up study for capture of the wear particles; and the whole device is simple in structure.

The invention relates to a rapid identification method for a present generation genotype of a gramineous seed. The rapid identification method comprises the steps of seed processing, seed genome DNA extracting and identifying, target gene amplifying and detecting and the like. According to the method, genome DNA of the single seed can be rapidly obtained in the seed period, and operation is easy and safe; the genotype of the seed can be identified in the seed period, the seed of the needed genotype is obtained and used for follow-up study, the field planting workload in the seeding period is reduced, the seed breeding efficiency is improved, follow-up growth and development of an embryo-containing seed are not damaged, and the seed can be preserved for a long time and also can be used for tissue culturing.

The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a method for solubilization and synchronous dissolution of bilobalide. The invention achieves solubilization and synchronous dissolution of bilobalide through a solid dispersion technology, a clathrate compound technology or a micronization technology. A bilobalide solid dispersion is prepared by a metlt extrusion method and a grinding method; a bilobalide clathrate compound is prepared by a grinding method, a saturated water solution method, a freeze drying method and a spray drying method; and a drug is subjected to micronization by using high-speed grinding. The method provided by the invention can substantially improve solubility of the bilobalide, speed up dissolution of the bilobalide, improve dissolution synchronization of effective components in the bilobalide, improve the bioavailability of the drug, and lay foundation for follow-up study of oral preparation.

The invention discloses a wear collection device for removing scalp myoelectric artifacts in EEG signals and belongs to the field of brain wave test storage and processing. Against artifacts caused byincomplete signals and scalp muscle movement caused by unknown contact between a dry electrode and scalp in the current EEG collection, according to the device, a telescopic structure is disposed onthe dry electrode to form EEG and scalp myoelectric sensors, the electrode follows the scalp to move, and two-channel signals, namely EEG signals and scalp myoelectric signals, are collected simultaneously in real time; an on-board processor analyzes EEG and scalp myoelectric signals at each time point in real time, gives the degree value of good contact between the electrode and the scalp, and performs data processing to eliminate the scalp myoelectric artifacts; and the processed EEG signals and the contact degree are uploaded through a wireless module to a client for follow-up processing. The device has the advantages that a hardware part achieves real-time automatic scalp myoelectric artifact removal of the EEG signals, the degree value of good contact between the electrode and the scalp is given accurately, and the wear collection device is of great significance for EEG collection and follow-up study.

The invention relates to a bismuth niobate-based glass ceramic material with high energy storage density as well as a preparation method and application thereof. A chemical composition of the bismuthniobate-based glass ceramic material accords with a general formula of 25Bi2O3-25Nb2O5-50SiO2, and a principal crystalline phase is bismuth niobate. The preparation method of the glass ceramic material comprises a step of preparing by adopting a high-temperature melting-controlled crystallization method. Compared with the prior art, the bismuth niobate-based glass ceramic material disclosed by theinvention has high energy storage density and excellent temperature stability, and also has the advantages of the characteristics of simplicity in preparation method and low cost, high follow-up study application potential and the like.

The invention discloses a temporary control system and method for floating buckling of a land buried pipeline. The system comprises a target control pipe section and an auxiliary control pipe section, wherein the target control pipe section is composed of a floating buckling section pipeline body, an upstream extension pipeline and a downstream extension pipeline; the auxiliary control pipe section is composed of an upstream far end auxiliary lifting section and a downstream far end auxiliary lifting section; and lifting points and strain rosettes are arranged on the target control pipe section and the auxiliary control pipe section, cushion layers are arranged at the suspension positions of the land buried pipeline, and covering layers are arranged at the exposed positions of the land buried pipeline. By adjusting the bending postures of a floating buckling section and upstream and downstream connecting sections of the floating buckling section and using an auxiliary bending pipe section to absorb the pipeline additional axial deformation quantity caused by excavation, so the purposes of uniform distribution and total control of stress are achieved, the stress and strain of pipelines everywhere are monitored, the safety of continuing service of the pipelines is guaranteed, and abundant analysis time and favorable construction conditions are created for follow-up study to develop a complete buckling control scheme. The system is clear in principle, quick in construction and good in motility.

The invention provides a method for mass propagation of lycoris aurea through somatic embryogenesis. The lycoris aurea tissue culture method for scale production and propagation so as to meet the market demand comprises the steps of A, explant disinfection, B, adventitious bud induction, C, callus induction, D, callus propagation, E callus redifferentiation, F, rooting culture, and H, seedling exercising and transplanting. According to the method, herbicide picloram is applied to tissue culture of lycoris aurea for the first time, stable lycoris aurea tissues capable of being propagated on a large scale are obtained, the callus induction rate reaches 95% or above, and the propagation coefficient of the lycoris aurea is at least increased by 8-10 times. The production cost is reduced, furthermore, the whole fine properties of a parent body can be preserved, and the inheritable character is stable. Through the method, a large number of excellent test-tube seedlings can be formed within a short period of time, large-scale industrialized production is conducted, and a lot of raw materials are provided for ornamental horticulture, pharmacy and other industries as well as the follow-up study of the lycoris aurea.

The invention discloses an automatic assembling device for an automobile seat sliding rail. The automatic assembling device for the automobile seat sliding rail comprises a sliding rail placing mechanism, a sliding rail core conveying mechanism, a ball and nylon rod loading mechanism and a base, wherein the sliding rail placing mechanism comprises two locating shafts and a sliding rail placing table; the sliding rail core conveying mechanism comprises two guide rails, a lead screw, a guide rail sliding block, a sliding rail core displacement table, a clamping device, a first servo motor and aguide rail support; and the ball and nylon rod loading mechanism comprises a loading frame, two stepped shafts, two stepped shaft supports, a nylon rod material frame, two ball material frames, a ballloading track, a nylon rod loading track and two second servo motors. The automatic assembling device disclosed by the invention has the advantages that all the parts cooperate, automatic assemblingof the automobile seat sliding rail is realized, labor cost is saved, time is shortened, efficiency is improved, and follow-up study on automobile seat sliding rail streamlined assembling can be carried out by utilizing the automatic assembling device disclosed by the invention.

The invention discloses an irradiated thin-wall aluminium pipe splitting device and a splitting method, and belongs to the field of pipe cutting devices. The irradiated thin-wall aluminium pipe splitting device comprises a lathe bed; a transverse mounting plate is arranged on the lathe bed; the upper end of the transverse mounting plate is connected with a transverse sliding table; a longitudinalsliding table is connected with the upper end of the transverse sliding table; a workpiece main shaft component is connected with the upper end of the longitudinal sliding table; an internal-expandingexternal-clamping clamp is arranged at the front end of the workpiece main shaft component; the axis of a thin-wall aluminium pipe is perpendicular to the moving direction of the longitudinal slidingtable; a chip collecting device is arranged on the lathe bed; a precision milling component and a lathe tool holder are arranged on two sides of the chip collecting device; an electric control cabinet is arranged on one side of the lathe bed; and an electric control component for controlling the splitting device to operate is arranged in the electric control cabinet. Automatic cutting and splitting operation is completed on a same device, the processing quality is ensured, the physical performance of a workpiece is not damaged, the purposes of automatic cutting and splitting sampling are achieved, and reliable support is provided for follow-up study of a reactor.

The invention provides use of acylcarnitine or detection reagent thereof. Specifically, through 6 years of follow-up study on 2103 residents, a targeted metabonomic strategy is employed to determine that an acylcarnitine spectrum, especially a long-chain acylcarnitine spectrum can be used as the marker for effective prediction of the onset risk of type 2 diabetes mellitus, and also can significantly improve the prediction ability of traditional risk factors for new-onset type 2 diabetes mellitus, thus providing favorable guidance for clinical diagnosis and treatment.

The invention discloses a method and a device for detecting and selecting laser-induce enhanced Raman spectrum in a liquid. The method comprises the following steps of: focusing the inducing light on a suspending to-be-detected sample and forming a three-dimensional light well in liquid; enriching metal nanoparticles on the surface of the to-be-detected sample; and coinciding the focuses of exciting light and inducing light, thereby forming a laser-induce enhanced Raman signal. The realizing method disclosed by the invention is simple and convenient, is obvious in spectrum enhancing effect and is fit for quick detection for in-situ Raman spectrum of a biological sample under a liquid environment; the to-be-detected sample and the metal nanoparticles are hatched together; the method is especially fit for the field of quick detection for diseases, epidemic situation, food safety, and the like; the toxic damage to the biological sample caused by the metal nanoparticles is greatly reduced, so that the true physiological status of living cell can be extremely reflected; the optical tweezers formed according to the method provided by the invention can be used for sorting, extracting and eluting, can realize the function of identifying and sorting Raman spectrum of a single living cell, and is beneficial to the follow-up study on the biological sample.

The invention relates to novel compounds, a preparation method and use thereof, in particular to halogenated hydroxyl aromatic methane compounds, a preparation method and use thereof, which solves the problem that halogenated hydroxyl aromatic methane lead compounds from natural sources are high in extraction cost, low in yield and difficult to develop follow-up study. The compounds have a structural formula, wherein R1' is one or more hydroxyl or hydrogen atoms in any position on an A ring; R2' is one or more hydroxyl or hydrogen atoms in any position on a B ring; and X is one or more halogen or hydrogen atoms in any position on the A ring or the B ring. A synthesis method has the advantages of mild reaction conditions, widely readily available raw materials, simple preparation method, high yield, low cost and the like, and is suitable for industrial production. The synthesized halogenated hydroxyl aromatic methane compounds and non-toxic salts, ester and ether thereof have the activity of resisting bacteria, tumors, oxidation and vascular endothelial cell injury and inhibiting proliferation of vascular smooth muscle cells.

The patent of the invention, which belongs to the field of deep sea geological exploration equipment, particularly relates to a hand-held columnar sediment sampler comprising a separating rubber sleeve, a sampling head, an outer sampling cylinder, an inner sampling cylinder, an end-portion sealing head, a water passing sealing cover, an unlocking sliding block and a locking sleeve and the like. The outer sampling cylinder and the inner sampling cylinder are made of transparent materials; and the locking sleeve is made of a high-elasticity material, the lower part of the locking sleeve is installed at a cylindrical inner-side mounting bench of an upper mounting cylinder, and an upper clamp plate is installed in a radial mounting notch. According to the invention, in-situ sealing is realizedby a sealing mechanism after sampling completion; and secondary sampling is realized by using an unlocking mechanism. Therefore, the sample loss in the sampling and transferring processes can be reduced; with the secondary sampling, the sampling success rate can be ensured; the sampling efficiency can be improved; and the bottom water covering can be stored while the sediments can be collected, so that the follow-up study can be performed conveniently.