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12 results about "Interferome" patented technology

Interferome is an online bioinformatics database of interferon-regulated genes (IRGs). These Interferon Regulated Genes are also known as Interferon Stimulated Genes (ISGs). The database contains information on type I (IFN alpha, beta), type II (IFN gamma) and type III (IFN lambda) regulated genes and is regularly updated. It is used by the interferon and cytokine research community both as an analysis tool and an information resource. Interferons were identified as antiviral proteins more than 50 years ago. However, their involvement in immunomodulation, cell proliferation, inflammation and other homeostatic processes has been since identified. These cytokines are used as therapeutics in many diseases such as chronic viral infections, cancer and multiple sclerosis. These interferons regulate the transcription of approximately 2000 genes in an interferon subtype, dose, cell type and stimulus dependent manner. This database of interferon regulated genes is an attempt at integrating information from high-throughput experiments and molecular biology databases to gain a detailed understanding of interferon biology.

Interferometric measurement method

PendingDE102024135315A1Using optical meansInterferomeOptical surface
In a method for the interferometric determination of the shape of a freeform optical surface of a test specimen using an interferometer, the specimen is successively positioned in different measurement positions. These positions include a nominal position and a multitude of non-nominal positions that deviate from it, each of which can be described by a change in position relative to the nominal position. An interferogram is recorded in each measurement position, and phase information derived from the interferogram is evaluated to determine the surface shape. An interferometer error tilt sensitivity is determined by means of position changes in the form of tilts. A shear of the surface form error is determined by means of position changes in the form of displacements. Through integration, the surface form error, and consequently the interferometer error, can be determined.
Owner:CARL ZEISS SMT GMBH

Interferometric test setup for testing the surface shape of a test object

PendingDE102024208940A1Using optical meansInterferomeReference wave
The invention relates to an interferometric testing arrangement for testing the surface shape of a test object, comprising a lighting device (105, 205, 305) for generating an input wave from electromagnetic radiation produced by a light source and an interferometer (150) in which, after splitting the input wave into at least one test wave directed towards the test object (170) and a reference wave, testing the surface shape of at least a partial surface of the test object (170) can be carried out by interferometric superposition of the at least one test wave and the reference wave, wherein a diffuser (130, 230, 330) is arranged in the lighting device, wherein the lighting device has a first optical path (110, 210, 310) and a separate second optical path (120, 220, 320), and wherein the input wave is transmitted via both the first optical path (110, 210, 310) and the second optical path (120, 220, 320). 220,320) can be coupled into the interferometer (150).
Owner:CARL ZEISS SMT GMBH

Flexible micro-nano fiber multiplexing chip and monitoring system and method thereof

This invention provides a flexible micro / nano fiber optic multiplexed chip and its monitoring system and method, belonging to the field of biomedical sensing technology. It includes: a myocardial marker detection layer with an embedded array of micro / nano fiber optic interferometers modified with different biological probes for simultaneous detection of multiple cardiovascular disease markers in sweat; a microfluidic channel layer with microfluidic channels for collecting and transmitting sweat and an outlet for sweat excretion; and a pulse wave monitoring layer with an embedded U-shaped micro / nano fiber for real-time pulse wave monitoring based on the bending loss principle, with a localized microfluidic channel inlet for sweat collection. Through the above technical solution, dual-modal multi-information synchronous monitoring is achieved, with high performance and high reliability.
Owner:HANDAN COLLEGE

Systems and methods for utilizing interferometric ultra-high resolution 3D imaging

The invention generally relates to systems and methods for utilizing interferometric ultra-high resolution 3D imaging. In certain aspects, the invention provides a system for achieving molecular resolution through tissues, the system comprising: an interferometric apparatus; and a control unit comprising one or more processors configured to: receive interferometric tissue data from the interferometric apparatus, wherein the interferonic tissue data comprises one or more tissue-induced abberations; apply a 4Pi in-situ point spread function (PSF) retrieval algorithm to the interferonic tissue data, thereby enabling direct retrieval of an aberrated, time-dependent in-situ model of single-molecule emission pattern from the interferonic tissue data, wherein the in-situ model reflects distortions, blurring, and / or partial coherence encountered during detection; and minimize disparities between the interferonic tissue data and the in-situ model to thereby provide accurate molecular localizations in the presence of tissue-induced aberrations.
Owner:PURDUE RES FOUND

Interferometer direction finding result quality assessment method, device and medium

ActiveCN115598584BRadio wave direction/deviation determination systemsRadio wave finder monitoring/testingPhase differenceInterferome
The application discloses an interferometer direction finding result quality evaluation method, equipment and medium, wherein the evaluation method comprises the following steps: performing reverse calculation on the theoretical phase difference by using the azimuth of direction finding and the baseline length; then, based on the difference between the real measurement phase difference and the theoretical phase difference of each baseline, calculating the threshold value by using the signal-to-noise ratio and the maximum phase difference tolerance during the design of the antenna baseline; then, obtaining the direction finding result quality evaluation of each baseline by using the relationship between the difference and the threshold value; finally, performing result fusion on the direction finding result quality evaluation data of each baseline by multiplication, so as to obtain the final interferometer direction finding result quality evaluation. The direction finding result quality evaluation data can be used to evaluate whether the interferometer direction finding result is reliable, so as to prevent the problem of performance decline of the equipment due to the direction finding error.
Owner:SOUTHWEST CHINA RES INST OF ELECTRONICS EQUIP

An interferometer direction finding resolution unscrambling method, system and medium for a shaped array

The application discloses an interferometer direction-finding demodulation method, system and medium for a special-shaped array, and the method comprises the following steps: selecting two pairs of baseline longest antenna elements to form a first interferometer; calculating the maximum ambiguity number of the interferometer measurement phase difference according to the interferometer vector of the first interferometer, and calculating the target unit vector coordinate estimation value corresponding to all ambiguity combination in the range with the maximum ambiguity number as the boundary; forming a corresponding second interferometer with the remaining antenna elements, calculating the cost function corresponding to all ambiguity combinations according to the target unit vector coordinate estimation value and the measurement phase difference of each pair of second interferometers; searching for the minimum value of the cost function, taking the ambiguity combination corresponding to the minimum value of the cost function as the ambiguity number estimation result, obtaining the target unit vector coordinate estimation value corresponding to the ambiguity number estimation result, and calculating the corresponding azimuth and elevation angle estimation value. The application solves the problem of interferometer direction-finding demodulation of a special-shaped array.
Owner:HUNAN ECONOVEL TECH CO LTD

Interferometric test arrangement for testing the surface shape of a test object

PCT designated stageWO2026061702A1Using optical meansLight spotInterferome
The invention relates to an interferometric test arrangement for testing the surface shape of a test object, comprising an illumination device (105, 205, 305) for generating an input wave from electromagnetic radiation generated by a light source, and an interferometer (150) in which, after the input wave has been split into at least one test wave directed onto the test object (170) and a reference wave, the surface shape of at least one partial surface of the test object (170) can be tested by interferometrically superimposing the at least one test wave and the reference wave, wherein a diffusing plate (130, 230, 330) is arranged in the illumination device, wherein the illumination device has a first optical path (110, 210, 310) and, separate therefrom, a second optical path (120, 220, 320), wherein the input wave can be coupled into the interferometer via both the first optical path and the second optical path, wherein, when the input wave is coupled in via the first optical path, a light spot generated on the diffusing plate has a first diameter (D1), and wherein, when the input wave is coupled in via the second optical path, a light spot generated on the diffusing plate has a second diameter (D2) which differs from the first diameter (D1). (Figure 1a)
Owner:CARL ZEISS SMT GMBH

Hydrogel functionalized optical fiber cortisol sensor and preparation method thereof

PendingCN121431439APhase-affecting property measurementsAntigenConcentration Response
The invention provides a hydrogel functionalized optical fiber cortisol sensor and a preparation method thereof, and belongs to the technical field of optical fiber biomass sensing. The effective refractive index of the hydrogel film coated on the surface of the optical fiber in the sensing area is changed by utilizing antigen-antibody specific binding, so that the effective refractive index of the sensing arm of the optical fiber Mach-Zehnder interferometer in the sensing area is changed, and the interference spectrum of the sensor is changed; by demodulating cortisol concentration response of a sensor interference spectrum, concentration measurement of cortisol to be measured can be realized, and high-sensitivity and specific recognition of cortisol is realized; in addition, the hydrogel functionalized optical fiber cortisol sensor provided by the invention is stable in structure, high in integration level and high in sensitivity, and can be used for accurately measuring the concentration of cortisol in media such as saliva.
Owner:HARBIN UNIV OF SCI & TECH

OFDR type esophageal squamous carcinoma marker detection device and functionalization and detection method

The invention discloses an OFDR type esophageal squamous carcinoma marker detection device and a functionalization and inspection method, and relates to the field of distributed optical fiber biochemical sensing, the device comprises a light splitting assembly, an interference assembly and a demodulation processing assembly, the light splitting assembly is used for splitting frequency linear tuning laser into auxiliary interferometer light and main interferometer light, and the interference assembly is used for receiving the auxiliary interferometer light and the main interferometer light; and splitting the primary interferometer light into reference light and measurement light; the demodulation processing assembly is used for collecting interference signals and calculating wavelength drift results of the stepped conical optical fiber in various refractive index environments in combination with a cross-correlation algorithm and a reference RBS signal; the main interferometer comprises a stepped conical optical fiber used for receiving measuring light and generating backward Rayleigh scattering light, and the stepped conical optical fiber comprises a first target conical region of a middle thin conical region part and second target conical regions located on the two sides of the first target conical region. According to the application, the high-precision detection of the Cyfra21-1 protein concentration in the serum of the esophageal squamous carcinoma patient can be realized.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV

OFDR type esophageal squamous cell carcinoma marker detection device and functionalization and inspection method

The application discloses an OFDR type esophageal squamous cell carcinoma marker detection device and a functionalization and inspection method, relates to the field of distributed optical fiber biochemical sensing, and comprises a light splitting assembly, an interference assembly and a demodulation processing assembly. The light splitting assembly is used for splitting a frequency linearly modulated laser into auxiliary interferometer light and main interferometer light, and splitting the main interferometer light into reference light and measurement light. The demodulation processing assembly is used for collecting interference signals, and combining a cross-correlation algorithm and a reference RBS signal to calculate wavelength drift results of the stepped taper optical fiber in various refractive index environments. The main interferometer comprises a stepped taper optical fiber used for receiving measurement light and generating back Rayleigh scattering light. The stepped taper optical fiber comprises a first target taper region of a middle thin taper region part and a second target taper region located on both sides of the first target taper region. The application can realize high-precision detection of the Cyfra21-1 protein concentration in the serum of an esophageal squamous cell carcinoma patient.
Owner:XIEHE HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI & TECH UNIV