12 results about "Pollakisuria" patented technology

The invention discloses a traditional Chinese medicine composition for treating recurrent urinary tract infection as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from 30-90 parts of astragalus membranaceus, 3-9 parts of cordyceps mycelia, 12-36 parts of rhizoma anemarrhenae, 10-30 parts of golden cypress and 6-18 parts of cinnamon. According to the pathogenesis characteristics of recurrent urinary tract infection and the principle of treatment based on syndrome differentiation of traditional Chinese medicine, the optimal raw material composition and dosage part ratio are obtained through screening, simplification and optimization of a large number of experiments, and the traditional Chinese medicine composition can remarkably improve the frequent micturition symptom, bacterial load and bladder pathological injury of rUTI mice. In addition, the drug-containing serum can promote migration of the SV-HUC-1 cells and reduce the level of inflammatory factors secreted by co-culture of the SV-HUC-1 cells and the UTI89 cells; the adhesion and internalization of the UTI89 to the cells are reduced. In addition, according to different bacterial strains and mouse modeling results, it is found that the modeling rate is obviously increased in a mode of enhancing infection every 24 hours, a recurrent urinary tract infection model of UTI89 infected C57BL / 6J is constructed, and a stable model is provided for screening drugs for treating recurrent urinary tract infection.

The purpose of the present invention is to provide a novel medical application using pluripotent stem cells in regenerative medicine. The present invention provides a cell formulation and pharmaceutical composition that are for amelioration and therapy for frequent urination and bladder pain caused by the inflammation of the bladder and that contain SSEA-3 positive pluripotent stem cells isolated from cultured mesenchymal cells or a mesenchymal tissue of a living organism. The cell formulation according to the present invention is considered to be based on a mechanism in which, for example, Muse cells are administered against interstitial cystitis having the abovementioned disorders to be successfully engrafted into affected bladder tissue, whereby the disorders are ameliorated and treated.

The invention provides a traditional Chinese medicine compound preparation for treating vaginitis and urethritis and a preparation method thereof. The preparation is prepared from nine traditional Chinese medicines including coptis chinensis, scutellaria baicalensis, radix sophorae flavescentis, cortex dictamni, fructus kochiae, fructus cnidii, rhizoma smilacis glabrae, gallnut and alum according to a specific weight ratio. The prescription is scientific in compatibility, has the remarkable effects of clearing away heat and drying dampness, detoxifying and killing insects, astringing and arresting leucorrhea, dispelling wind and arresting itching, and has the remarkable effect on symptoms such as pruritus vulvae, abnormal leucorrhea, frequent micturition and urgent micturition. The preparation disclosed by the invention can be prepared into a plurality of external dosage forms such as washing liquid and effervescent tablets, is safe and convenient to use, definite in curative effect and low in recurrence rate, and has a good clinical application prospect and market value.

The application discloses a traditional Chinese medicine composition for auxiliary treatment of prostatic hypertrophy and a preparation method thereof. The traditional Chinese medicine composition is prepared from Uncaria, ethanol extract of Dehaasia bibracteata, Akebia quinata, Nelumbo nucifera, Crossandra infundibuliformis, Rosmarinus officinalis, Prunus armeniaca, Cinnamomum cassia and Salvia officinalis by processing. The traditional Chinese medicine composition has the effect of treating prostatic hypertrophy. The traditional Chinese medicine composition is mainly used for prostatic hypertrophy, and the symptoms include frequent urination, urgent urination and incomplete urination. The traditional Chinese medicine composition can reduce the prostate index of a patient with prostatic hypertrophy, regulate the sex hormone level, reduce the prostate phosphatase activity, and has a remarkable effect on treating the problems of frequent urination, urgent urination and incomplete urination caused by prostatic hypertrophy. Meanwhile, the composition is prepared from traditional Chinese medicines as raw materials, is safe to use, has high bioavailability, and has no any toxic and side effects.

Devices, systems, and methods are claimed for the treatment of male urinary frequency disorders using volumetric tissue heating, e.g., via radiofrequency (RF) or ultrasound (US) energy applied to pelvic floor tissue or penile tissue. In one embodiment, a device for the non-invasive treatment of urinary frequency disorders is disclosed, the device being applicable externally to a perineal region of a male individual, the device comprising: at least one radiofrequency (RF) generator configured to generate RF energy; at least one RF electrode suitable for placement on a target perineal surface; and at least one control circuit connected to the RF generator, wherein the at least one control circuit is operable to cause the RF energy to selectively heat a portion of a urethra, a portion of one or more pelvic floor muscles, a portion of a prostate gland, or a portion of a urinary bladder.

The invention relates to the use of epidermal growth factor for the manufacture of a medicament for the treatment of interstitial cystitis. The "epidermal growth factor" (EGF) of the invention can be used to manufacture an excellent medicament for interstitial cystitis. The medicament has a composition that includes an active ingredient, adjuvant, dispersant, wetting agent, and / or suspension agent. The carrier of the epidermal growth factor is water, colloid, hyaluronic acid, natural oils, and / or glucose. The medicament serves to reduce urinary frequency. The medicament serves to restore bladder elasticity. The medicament serves to reduce cystitis. The medicament serves to increase the antioxidant capacity in bladder tissue.The present invention proposes a novel effect of epidermal growth factor, which can be used to treat interstitial cystitis and to repair the bladder mucosa and exhibits excellent efficacy.

A urine exosome marker panel for detecting bladder cancer and the use thereof. The provided biomarker panel comprising IGF2, KRT20, SPAG5, NRP1 and DHRS2 is used for detecting bladder cancer patients. The marker panel is used to construct a prediction model, and the model is trained by means of a training set and optimized by means of a test verification set, so as to finally obtain an early diagnosis prediction model for bladder cancer. The provided exosome marker panel and prediction model enable relatively accurate early screening of clinical samples from patients clinically suspected of having bladder cancer, presenting with symptoms such as hematuria, frequent urination, urgent urination, and dysuria, and for whom cystoscopy is recommended by clinical diagnosis, wherein the optimal marker panel is IGF2+KRT20+SPAG5+NRP1, with an AUC of 0.902, a sensitivity of 86.8%, a specificity of 83.0%, and an accuracy of 84.8%, demonstrating favorable clinical diagnostic value.

The invention discloses a traditional Chinese medicine composition for treating prostatitis, frequent urination, urgent urination and anuresis, and belongs to the technical field of traditional Chinese medicines. The composition is prepared from the following raw materials in parts by weight: 3-10 parts of Chinese prickly ash, 4-20 parts of radix clematidis, 2-18 parts of mineral salt, 3-8 parts of calcined escargots and 3-22 parts of sedum sarmentosum. The invention also discloses a preparation method and application of the compound. The traditional Chinese medicine composition is simple in formula, has the effects of warming and activating meridians, softening hardness to dissipate stagnation, clearing heat and promoting diuresis and relieving swelling and pain by being applied to the navel (Shenque acupoint), and is used for treating prostatitis and related urinary system symptoms. The traditional Chinese medicine is quick in effect, short in treatment course, definite in curative effect, green, safe, free of side effects, convenient to use and low in cost, and provides an excellent external treatment choice for patients.

The present invention relates to a medical device, and specifically relates to a urinary catheter with a urinary catheter top end made of a multi-layer composite material. The technical problem to be solved by the present invention is that the material used in the existing urinary catheters is relatively hard for the bladder mucosa, and the relatively hard top end of the urinary catheter may press and stimulate the bladder wall to cause bladder stimulation symptoms such as frequent urination, urgent urination, abdominal pain, and intense sensation of holding back urine. According to the present invention, the top end of the urinary catheter is made of a multi-layer composite material and is formed by nesting two or more layers of materials with different hardness, wherein the innermost layer is an inner lining layer, and the inner lining layer is continuous with the wall of the remaining urinary catheter but has a smaller thickness. A soft cushion layer is nested on the surface of the inner lining layer, the soft cushion layer is made of a softer material than the inner lining layer, and one or more film layers may be additionally disposed on the outer side of the soft cushion layer to wrap the soft cushion layer inside a closed cavity. The present invention has the beneficial effects that the top end of the urinary catheter is of a layered structure, and the hardness of different layers of materials is different, wherein the part of the outer layer in direct contact with the bladder wall is made of a super-flexible material so as to reduce the compression on the bladder mucosa, and the inner layer and other parts of the urinary catheter are made of relatively hard materials so as to ensure the support degree of the urinary catheter.

The invention relates to the technical field of biological materials, in particular to a polydopamine coating as well as a preparation method and application thereof. According to the specific technical scheme, a dopamine solution and a hydrogen peroxide aqueous solution are mixed on the surface of a base material to be coated, and the polydopamine coating is generated. The prepared polydopamine coating can effectively improve the lower urinary symptoms such as pathological bladder mucous membrane barrier damage, erosion, bleeding, pain, frequent urination and urgent urination, mucous membrane repair is accelerated, and the life quality of a patient is improved. The technical scheme provided by the invention has a wide application prospect in the field of chemical cystitis treatment.

1. The name of the design product: photon therapy instrument. 2. The use of the design product: for treating prostate-related diseases, such as frequent urination, urinary urgency, hematuria, and prostate hyperplasia. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective drawing.

The invention discloses a traditional Chinese and western medicine synergetic postpartum pelvic repair technique and device. The mechanical balance of pelvic floor is intervened and reconstructed through a systematic technique. The method integrates the traditional Chinese medicine meridian theory and the western medicine anatomy structure, comprises a targeted stimulation scheme of key structures such as vulva vestibular glands, anus external sphincter and piriformis, can effectively improve symptoms such as postpartum sexual intercourse pain, vagina blowing, frequent urination and urgent urination in combination with a biomechanical feedback regulation mechanism, and has the characteristics of being simple and convenient to operate, noninvasive and safe.