The invention relates to a cutting device for sheet metal processing. The cutting device comprises a lathe body, a walking frame and a laser cutting head, the lathe body is provided with a clamping device and a flow guide hole, a water circulation mechanism is arranged in the lathe body, the outer periphery of the laser cutting head is provided with a protective mechanism, the protective mechanismincludes a clamp, a hollow ring and a plurality of water spray components, each water spray component include a connection seat, a water curtain nozzle and a connection pipe, the water circulation mechanism includes a filter screen, a water tank, a circulation pump and a water supply joint, and the clamping device includes a jacking air cylinder, a clamping plate and a plurality of pressing components. In the cutting device for sheet metal processing, a water curtain can be used for cooling and intercepting high-temperature sparks to prevent the sparks from harming operators and prevent hidden fire hazards; collection of waste debris such as the sparks is simple and convenient to realize, and the difficulty of equipment cleaning is reduced; water recycling is realized, and water resourcesand processing cost are saved; and sheet metal parts in different shapes and sizes can be fixed, the application scope is wide, and the fixing effect is good.