The invention discloses a semi-integrated seamless bridge structure adaptive to a soft foundation. The semi-integrated seamless bridge structure comprises a main beam, piers, approach slabs and abutments, wherein the main beam and the approach slabs are connected into a whole, and the upper surface of the whole is sequentially paved with a bituminous concrete pavement layer, a waterproof layer and a leveling layer of a reinforced concrete pavement layer from top to bottom. Pavement steel bars are arranged in the reinforced concrete pavement layer. The main beam comprises a plurality of spans, a pull-press combined component is arranged between every two adjacent spans, and pull-press combined components are also arranged between the main beam and the approach slabs. Each pull-press combined component comprises a reinforcing steel bar, a PBL anti-shearing device perforated panel, a hole-penetrating steel bar, a pull-resisting top plate, a shallow embedded plate, deep embedded plates and a beam end trapezoidal lug pressing rod. The continuous main beam structure is simplified into the continuous pull-press combined components on a bridge deck, additional internal force brought by differential settlement to the structure is remarkably reduced, and material consumption is lowered; and meanwhile, side effects caused by adding of materials are avoided. The construction process and the structure form are simplified, the structure stress performance is improved, and the construction quality is easy to guarantee.