The invention discloses a wear-resistant vanadium-titanium gear and a preparation method thereof. The wear-resistant vanadium-titanium gear is composed of the following components in percentage by weight: 0.18-0.33% of carbon, 2.3-3.8% of chromium, 0.3-0.5% of manganese, 0.17-0.25% of silicon, 3.8-4.2% of nickel, 1.0-1.8% of tungsten, 1.10-2.15% of vanadium, 1.48-2.57% of titanium, 0.21-0.34% of copper, 1.3-2.1% of molybdenum, 0.18-0.32% of rare earth, 0.0018-0.0041% of boron, at most 0.035% of sulfur and phosphorus, and the balance of iron and inevitable impurities. The method comprises the following steps: preheating treatment, isothermal annealing treatment, primary quenching, primary tempering, carburizing treatment, high-temperature tempering, secondary quenching, secondary tempering and shot blasting. The finally obtained gear has the advantages of high mechanical properties (wear resistance, fatigue resistance, hardness and the like), favorable comprehensive properties and longer service life, and is especially suitable for the high-speed heavy-load high-impact-force occasions with the gear module of greater than 6.