The invention relates to a synthesizing method for 4-oxethyl-1,1,1-trifluoro-
butene-2-
ketone. The method comprises the following steps that 
dichloromethane and 
pyridine are added in a reaction kettle, on the condition that the temperature is controlled at minus 10 DEG C-0 DEG C, 
trifluoroacetic acid is dropwise added, the dropwise adding time is controlled for 3-3.5 hours, and after dropwise adding is completed, stirring is performed for ten minutes; vinyl ethyl 
ether is added, on the condition that the temperature is controlled at minus 10 DEG C-0 DEG C, methylsulfonyl 
chloride is dropwise added, the dropwise adding time is controlled for 2 hours, after dropwise adding is completed, the temperature is slowly increased to 20 DEG C, and stirring is performed for staying overnight; filter pressing is performed on obtained products with a plate-and-frame 
filter press, and filter cakes are washed for two times with 
dichloromethane to collect 
pyridinium; normal-pressure desolventizing is performed on filtrate at 58 DEG C, the temperature is lowered to 20 DEG C to collect 
solvent, reduced-pressure distilling and desolventizing are performed at 58 DEG C to collect 
solvent to obtain crude products, reduced-pressure rectifying is performed on the crude products to collect overhead products, and the 4-oxethyl-1,1,1-trifluoro-
butene-2-
ketone is obtained. The synthesizing method for the 4-oxethyl-1,1,1-trifluoro-
butene-2-
ketone has the advantages of being simple and direct in technology, few in technology waste materials, high in yield and suitable for large-scale industrialized production.