The invention discloses a production process for casting a core mold part based on a lost foam technology. The production process comprises the following steps of A, preparing a core mold model; b, preparing a core model cluster; c, pretreatment of model casting, specifically, burying the core model cluster into a sand box, compacting molding sand in the sand box, covering the molding sand with a plastic film, and performing primary vacuumizing treatment on the sand box to enable the interior of the sand box to be in a negative pressure state; d, casting; and e, post-treatment of model casting, specifically, uncovering the plastic film on the sand box, carrying out secondary vacuumizing on the interior of the sand box, taking out a fully cooled core mold casting from the sand box, and carrying out size and shape finish machining treatment to obtain the core mold part. The core mold part manufactured through the production process has the advantages of being high in size precision and low in surface roughness, the production process is simple, the production cost is greatly reduced, material consumption is low, and production process has high popularization value in the field of core mold part casting.