A manufacturing process of a smoke waste heat exchanger for a radiant tube burner sequentially comprises the steps of assembling of an external air guide tube and an air inlet tube, assembling of a sealing head and an external fin heat exchange tube, assembling of the external fin heat exchange tube, the external air guide tube, the air inlet tube and a jacketed tube, assembling of a special flange, a smoke guide tube and a blocking plate, assembling of an air inlet flange and a reinforcing tube, assembling of a heat exchange ring, an air jet flow tube, a bending tube and a middle guide tube, assembling of the smoke guide tube, a smoke outlet flange and a smoke outlet tube, and assembling of a flow baffle and lifting lugs. The steps are bridged well, and are proper, the production efficiency is improved, meanwhile, the welding process is flexible and changeable, the welding deformation amount is small, and the welding line quality is greatly improved. According to the manufacturing process, the welding quality is good, and the production efficiency is higher.