10 results about "Dipsacus asperoides" patented technology

This invention discloses a traditional Chinese medicine composition for preventing and treating inflammatory diseases in animals, its preparation method, and its application, belonging to the field of traditional Chinese medicine composition technology. The raw materials of this traditional Chinese medicine composition for preventing and treating inflammatory diseases in animals, by mass percentage, include 8%-12% extract of honeysuckle branches and leaves, 8%-12% extract of dipsacus root, 8%-12% chrysanthemum, 4%-6% mulberry leaves, 4%-6% licorice root, 0.8%-1.2% peppermint, and 50.8%-67.2% anhydrous glucose. It has good anti-inflammatory effects and can effectively alleviate inflammatory responses caused by LPS. In particular, it has good therapeutic and ameliorative effects on the clinically prevalent porcine reproductive and respiratory syndrome (PRRS) and infectious bronchitis in chickens, effectively reducing morbidity and mortality, and improving production performance.

This invention discloses a method for determining the content of a traditional Chinese medicine compound containing honeysuckle, isatis root, and scutellaria. The method includes the following steps: taking a test solution of the traditional Chinese medicine compound, a first reference solution, and a second reference solution for detection. The chromatographic conditions are as follows: using a chromatographic column packed with octadecyl-bonded silica gel; mobile phase A selected from one or more of acetonitrile, methanol, and tetrahydrofuran; and mobile phase B being an acidic aqueous solution, an alkaline aqueous solution, and / or a buffer salt aqueous solution. The traditional Chinese medicine compound includes honeysuckle, isatis root, scutellaria, indigo leaf, forsythia, platycodon, patchouli, and licorice. The reference standards are baicalin, ammonium glycyrrhizate, honeysuckle saponin B, and dipsacus saponin B. The detection method of this invention is simple, accurate, efficient, stable, precise, reproducible, convenient, and easy to master. It can effectively save energy and reduce analytical costs, while this technology is not disclosed in existing technologies.

This invention proposes a traditional Chinese medicine compound for treating ankylosing spondylitis of the kidney-deficiency and damp-heat type accompanied by gastrointestinal dysfunction, along with its preparation method, belonging to the field of traditional Chinese medicine technology. The compound consists of Smilax glabra, Bletilla striata, Paris polyphylla, Geranium wilfordii, Dioscorea hypoglauca, Patrinia scabiosaefolia, Dipsacus asper, Drynaria fortunei, Pyrola rotundifolia, Clematis chinensis, Pheretima aspergillum, Lycopodium clavatum, Corydalis yanhusuo, Paeonia lactiflora, Atractylodes macrocephala (fried), Coix lacryma-jobi (raw), Aucklandia lappa, and Glycyrrhiza uralensis. This invention combines these herbs to achieve a synergistic effect, collectively clearing heat and dampness, strengthening the spleen and kidneys, and unblocking the meridians. The overall formula addresses both strengthening the body's foundation and eliminating pathogenic factors, ensuring unobstructed meridian flow and relieving arthralgia. This compound has the functions of clearing heat and dampness, strengthening the spleen and kidneys, and unblocking the meridians. It offers a short treatment course, rapid efficacy, low recurrence rate after cure, few side effects, and is inexpensive and convenient to use for treating ankylosing spondylitis with gastrointestinal dysfunction.

The invention discloses a novel application of a Guangkang capsule medicine. According to the application of the Gukang capsule medicine in preparation of the medicine for treating gout, the medicine for treating gout is a medicine preparation prepared from an extract obtained by mixing and decocting 570 g of roots of Japanese banana, 400 g of creeping oxalis, 600 g of fructus psoraleae and 300 g of radix dipsaci with water, 150 g of pseudo-ginseng fine powder, 30 g of fine powder of the roots of Japanese banana and pharmaceutically acceptable auxiliary materials. Animal experiments show that the serum uric acid level of a hyperuricemia model mouse can be remarkably reduced, and joint swelling and inflammatory cell infiltration are relieved. Clinical observation further proves that the traditional Chinese medicine composition has a good curative effect on improvement of arthralgia, limited activity and other symptoms of gout patients, is relatively high in safety and does not have obvious adverse reaction.

The application relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition, a traditional Chinese medicine preparation, a preparation method and application thereof. The traditional Chinese medicine composition contains angelica sinensis, safflower, red peony root, salvia miltiorrhiza, radix aconiti kusnezoffii, radix aconiti carmichaeli, cassia twig, drynaria, radix rubi sylvestris, frankincense, myrrh, radix rubi sylvestris, natural copper, elderberry, radix curdlane, crab shell and zhangdan. The preparation method of the traditional Chinese medicine preparation comprises the following steps: mixing angelica sinensis, safflower, red peony root, salvia miltiorrhiza, radix aconiti kusnezoffii, radix aconiti carmichaeli, cassia twig, drynaria, radix rubi sylvestris, radix rubi sylvestris, natural copper, elderberry, radix curdlane and crab shell with vegetable oil to perform frying and boiling, performing solid-liquid separation to obtain medicine oil; mixing the medicine oil after being refined with zhangdan, frankincense and myrrh to obtain an ointment; soaking the ointment in water, taking out, heating and melting, mixing with blood ointment powder, and spreading. The traditional Chinese medicine composition and the traditional Chinese medicine preparation have the effects of setting bone, continuing tendon and relieving swelling and pain.

The invention discloses a method for simultaneously detecting contents of various active ingredients in Sanbi decoction based on HPLC (High Performance Liquid Chromatography), and belongs to the technical field of analytical chemistry. The method for determining the content of loganic acid, gentiopicroside, 5-O-methylvisammioside, dipsacus asper saponin VI and glycyrrhizic acid in the Sanbi decoction is successfully constructed by virtue of an HPLC (High Performance Liquid Chromatography) gradient elution technology. A content determination result shows that in 15 batches of samples, the content ranges of the five active ingredients are respectively 1.6584 mg / g to 4.0230 mg / g, 1.1120 mg / g to 4.0518 mg / g, 0.1688 mg / g to 0.4344 mg / g, 2.7441 mg / g to 10.3693 mg / g and 2.6289 mg / g to 5.0324 mg / g. According to the Chinese herbal medicine compound preparation pharmaceutical research technical guidance principle (trial) managed according to the ancient classical famous prescription catalog, the content ranges all meet the standard requirement of the mean value + / -3SD. Moreover, the method provided by the invention has good accuracy and reliability, and a scientific basis can be provided for the quality control and evaluation of the substance standard of the Sanbi decoction.

The invention belongs to the technical field of biological medicines, and particularly relates to application of dipsacus asper saponin B in preparation of a medicine for treating or preventing inflammatory bowel diseases. The technical problem to be solved by the invention is to provide a new choice for treatment of colitis. The technical scheme of the invention is application of dipsacus asper saponin B in preparation of drugs for treating or preventing inflammatory bowel diseases. The invention defines that the dipsacus asper saponin B has a treatment effect on colitis, systematically explains the mechanism of the dipsacus asper saponin B, and provides a brand new scientific basis and data support for development of the dipsacus asper saponin B as a medicine for treating inflammatory enteritis.

The invention provides a traditional Chinese medicine composition and application thereof in preparation of medicines for treating or preventing hyperuricemia, gout, uric acid kidney stone, gouty arthritis and gouty nephropathy. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 5 to 25 parts of raw radix astragali seu hedysari, 5 to 15 parts of radix morindae officinalis, 5 to 15 parts of radix dipsaci, 5 to 15 parts of flos lonicerae, 5 to 25 parts of herba hedyotis diffusae, 5 to 25 parts of terra flava usta, 5 to 25 parts of poria peel, 5 to 15 parts of radix puerariae, 5 to 15 parts of fructus rubi, 5 to 15 parts of fructus schisandrae chinensis, 5 to 15 parts of fructus akebiae and 5 to 15 parts of raw radix glycyrrhizae. Experiments show that after the traditional Chinese medicine composition is used for treatment, the symptoms of a patient are relieved, the uric acid value is reduced, liver and kidney function damage is avoided, and the effect is better than that of existing western medicines.

The application discloses a traditional Chinese medicine composition for senile dementia and stroke and a preparation method thereof, which is prepared from the following raw medicinal materials in parts by weight: 40 parts of Schinus molle, 10 parts of American ginseng, 8 parts of Panax notoginseng, 5 parts of hawthorn, 5 parts of Chinese yam, 5 parts of Herba Epimedii, 6 parts of Radix Curcumae, 5 parts of Poria cocos, 5 parts of Astragalus membranaceus, 5 parts of Codonopsis pilosula, 3 parts of Platycladus orientalis, 3 parts of Corydalis, and 5 parts of Cannabis sativa Linn. The application has the advantages that a nerve blood vessel unit system regulation mechanism is creatively proposed, the limitation of single target treatment is broken through, the Schinus molle, which is the monarch drug in the prescription, is rich in nervonic acid and neurotrophic factor-like substances, can directly act on neuron mitochondrial energy metabolism, improves brain tissue energy supply, and on the process level, the multi-stage dynamic extraction technology of the application innovates the traditional decocting mode.

The invention provides a traditional Chinese medicine compound for treating kidney-deficiency damp-heat type ankylosing spondylitis with gastrointestinal dysfunction and clearing away heat, eliminating dampness and dredging governor meridian and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine compound is prepared from rhizoma smilacis glabrae, rhizoma bletillae, rhizoma paridis, geranium wilfordii, rhizoma dioscoreae hypoglaucae, herba patriniae, teasel, rhizoma drynariae, herba pyrolae, radix clematidis, lumbricus, herba lycopodii, rhizoma corydalis, radix paeoniae rubra, roasted rhizoma atractylodis macrocephalae, raw semen coicis, costus root and liquorice. The medicines are combined, so that the effects of the medicines generate a synergistic effect, and the effects of clearing heat, eliminating dampness, tonifying spleen, tonifying kidney and dredging governor meridian are achieved together. The whole compatibility has the effects of consolidating root and eliminating evil, so that meridians and collaterals are dredged, and the arthralgia syndrome is solved. The traditional Chinese medicine compound has the functions of clearing heat, eliminating dampness, invigorating spleen, tonifying kidney and dredging governor meridian, and has the advantages of short treatment course, quick effect, low possibility of relapse after curing, small side effect, low price and convenience in use when being used for treating the ankylosing spondylitis accompanied by gastrointestinal dysfunction.