39 results about "Dipsacus asperoides" patented technology

The invention relates to the technical field of teasel breeding, and discloses a teasel germplasm resource multi-character collaborative screening breeding method, which comprises the following steps: multi-omics data acquisition: extracting teasel germplasm leaf DNA (deoxyribonucleic acid), and capturing exon regions of disease resistance and metabolism related genes by adopting a targeted sequencing technology to obtain an SNP (single nucleotide polymorphism) marker matrix; the method comprises the following steps: collecting root extracts, detecting medicinal components through ultra-high performance liquid chromatography-mass spectrometry, and constructing a metabolite abundance matrix; measuring phenotype data of plant height, root length, root weight, root rot morbidity and survival rate under drought stress; key site and metabolite correlation analysis: constructing a Bayesian network containing SNP markers, metabolite and phenotypes by using a graph database, and carrying out cross validation through a leave-one-out method. The dipsacus asper germplasm resource multi-character collaborative screening breeding method aims at solving the problem that a traditional breeding method lacks systematic integration analysis of genomes and metabolic pathways in dipsacus asper multi-character collaborative improvement.

The invention relates to the technical field of traditional Chinese medicinal material planting, and discloses a dipsacus asperoids medicinal material photoperiod regulation and control yield-increasing planting method which comprises the following steps: selecting and preparing a planting site, selecting a land parcel with sufficient illumination, good drainage and fertile soil as a planting shed base, and deeply ploughing 30 days before planting; teasel root seedlings which are 15-20 cm in plant height, complete in root system and free of plant diseases and insect pests are selected for field planting, the field planting time is the middle ten days of April in spring or the last ten days of September in autumn, the field planting density is that the row spacing ranges from 50 cm to 60 cm, the plant spacing ranges from 30 cm to 40 cm, and root fixing water is thoroughly watered after field planting; a photoperiod regulation and control system is built, an LED plant growth lamp is adopted as a supplementary light source, a light source spectrum is configured to be a combination of red light and blue light wavelengths, the light intensity ratio is 3: 1, and illumination parameters are set according to the teasel root growth stage. The dipsacus asperoids medicinal material photoperiod regulation and control yield-increasing planting method aims to improve the yield and quality of the dipsacus asperoids medicinal material by regulating and controlling the photoperiod.

The present invention discloses Jiangzhuo Quyu Granules for treating hyperlipidemia, which is a preparation made from raw medicinal materials in the following weight ratios: 20 - 30 parts of ginseng, 15 - 25 parts of atractylodes macrocephala, 20 - 30 parts of poria cocos, 18 - 22 parts of cuscuta chinensis, 12 - 18 parts of eucommia ulmoides, 10 - 20 parts of dipsacus asperoides, 20 - 30 parts of wolfberry fruit, 15 - 25 parts of safflower, 20 - 30 parts of motherwort, 10 - 20 parts of notoginseng, 10 - 20 parts of cistanche deserticola, 20 - 30 parts of cinnamon, 15 - 25 parts of epimedium, 12 - 18 parts of pinellia ternata, 20 - 30 parts of platycodon grandiflorum, 10 - 20 parts of fritillaria cirrhosa, 20 - 30 parts of sterculia lychnophora, 20 - 30 parts of peucedanum praeruptorum, 15 - 25 parts of mulberry bark, 20 - 30 parts of immature bitter orange, 15 - 25 parts of magnolia officinalis, and also discloses its preparation method and use in the preparation of drugs for treating hyperlipidemia, and the hyperlipidemia is of the phlegm-turbidity obstruction syndrome type.

The invention discloses a traditional Chinese medicine external application preparation for sciatica and femoral head injury and auxiliary treatment equipment. Taking the following materials: tonics: 10g of red ginseng, 10g of codonopsis pilosula, 10g of rhizoma polygonati, 10g of liquorice, 10g of angelica sinensis, 10g of turtle glue, 10g of radix rehmanniae, 10g of dogwood, 10g of cornu cervi pantotrichum, 10g of cistanche, 10g of morinda officinalis, 10g of herba epimedii, 10g of fructus psoraleae, 10g of semen cuscutae, 10g of eucommia ulmoides, 10g of teasel root, 10g of rhizoma drynariae, 10g of fructus alpiniae oxyphyllae, 10g of radix rehmanniae, 10g of turtle glue, 10g of rhizoma anemarrhenae, 10g of dogwood, 10g of parasitic The invention relates to the technical field of traditional Chinese medicine preparations, and has the beneficial effects that through the synergistic effect of compound optimization and intelligent equipment, the comprehensive treatment effects of efficient transdermal absorption, precise targeted treatment, safety and no side effect are realized, and the core problems of poor permeability, single curative effect, insufficient adaptability and the like of a traditional external treatment method are solved; and a safe, efficient and convenient solution is provided for sciatica and femoral head injury.

This invention discloses a traditional Chinese medicine composition for preventing and treating inflammatory diseases in animals, its preparation method, and its application, belonging to the field of traditional Chinese medicine composition technology. The raw materials of this traditional Chinese medicine composition for preventing and treating inflammatory diseases in animals, by mass percentage, include 8%-12% extract of honeysuckle branches and leaves, 8%-12% extract of dipsacus root, 8%-12% chrysanthemum, 4%-6% mulberry leaves, 4%-6% licorice root, 0.8%-1.2% peppermint, and 50.8%-67.2% anhydrous glucose. It has good anti-inflammatory effects and can effectively alleviate inflammatory responses caused by LPS. In particular, it has good therapeutic and ameliorative effects on the clinically prevalent porcine reproductive and respiratory syndrome (PRRS) and infectious bronchitis in chickens, effectively reducing morbidity and mortality, and improving production performance.

The invention relates to the technical field of traditional Chinese medicine external preparations, in particular to a bone strengthening emplastrum and a preparation method thereof. The invention relates to a bone strengthening emplastrum, which comprises the following medicines: safflower, belladonna liquid extract, corydalis tuber, menthol, divaricate saposhnikovia root, teasel root, cicada slough, suberect spatholobus stem, clematis root, camphor, monkshood, fleece-flower root, borneol, methyl salicylate, diphenhydramine and mature vinegar. The matrix comprises rubber, zinc oxide, rosin, vaseline, wool fat and gasoline; at least one of sodium polyacrylate, sodium alginate, xanthan gum, a hydrophobic modified product of the xanthan gum, chitosan, hydroxypropyl methyl cellulose and polyvinylpyrrolidone is added into the bone strengthening emplastrum. By adding the substances, the stability of the mucilage can be effectively improved, so that separation and layering of the mucilage are avoided, the technical problem of non-ideal product quality caused by poor stability of the mucilage of the bone strengthening rubber emplastrum and the preparation method of the bone strengthening rubber emplastrum can be solved, and the product quality and the application prospect are improved.

The invention provides application of dipsacus asper saponin VI in preparation of a medicine for preventing and / or treating tendon adhesion, and belongs to the field of biological medicine. The research finds that the dipsacus asper saponin VI can promote the polarization of macrophages to M2 type, inhibit the expression of a fibroblast marker alpha-SMA, and inhibit the expression of IGFBP-6 at the same time. The dipsacus asper saponin VI can inhibit tendon adhesion through multiple effects of resisting inflammation, inhibiting fiber activation and inhibiting IGFBP-6 expression, and can be used for preparing the medicine for preventing and / or treating tendon adhesion.

The invention relates to the field of traditional Chinese medicine external preparations, in particular to traditional Chinese medicine external liniment medicinal liquor for dispelling wind, eliminating dampness, activating blood and diminishing swelling, which comprises the following components in parts by weight: 5-15 parts of rheum officinale, 3-10 parts of arisaema consanguineum schott, 8-20 parts of mangnolia officinalis, 6-18 parts of liquorice, 5-12 parts of lotus powder, 10-25 parts of turmeric, 8-20 parts of golden cypress, 6-15 parts of pericarpium citri reticulatae, 5-12 parts of safflower, 8-18 parts of ligusticum wallichii, 10-25 parts of teasel root, 15-30 parts of eucommia ulmoides and 12-28 parts of rhizoma drynariae. The medicinal liquor is prepared from the following raw materials in parts by weight: 3-9 parts of dragon's blood, 8-20 parts of myrrh, 2-6 parts of pearl powder, 5-15 parts of mung bean seed-coat, 1-4 parts of borneol and 200-500 parts of Baijiu. Based on the innovative concept of eliminating evil, strengthening body resistance and multi-target cooperation, four functional components of expelling wind-damp, promoting blood circulation to remove blood stasis, strengthening tendons and bones and promoting tissue regeneration to heal sores are integrated, the limitation of traditional medicinal liquor is broken through through toxic effect balance compatibility and a gradient permeation process, and the externally applied medicinal liquor can improve local blood circulation, relieve inflammation pain and improve the curative effect of the traditional medicinal liquor. In addition, bone metabolism balance can be adjusted, tissue repair is promoted, and a novel treatment choice is provided for patients with chronic osteoarticular diseases and compound trauma.

This invention discloses a method for determining the content of a traditional Chinese medicine compound containing honeysuckle, isatis root, and scutellaria. The method includes the following steps: taking a test solution of the traditional Chinese medicine compound, a first reference solution, and a second reference solution for detection. The chromatographic conditions are as follows: using a chromatographic column packed with octadecyl-bonded silica gel; mobile phase A selected from one or more of acetonitrile, methanol, and tetrahydrofuran; and mobile phase B being an acidic aqueous solution, an alkaline aqueous solution, and / or a buffer salt aqueous solution. The traditional Chinese medicine compound includes honeysuckle, isatis root, scutellaria, indigo leaf, forsythia, platycodon, patchouli, and licorice. The reference standards are baicalin, ammonium glycyrrhizate, honeysuckle saponin B, and dipsacus saponin B. The detection method of this invention is simple, accurate, efficient, stable, precise, reproducible, convenient, and easy to master. It can effectively save energy and reduce analytical costs, while this technology is not disclosed in existing technologies.

The invention relates to the technical field of medicinal plant seedling raising, and discloses a dipsacus asperoids water-floating seedling raising method which comprises the following steps: seed pretreatment: performing physical hull breaking treatment and biological induction treatment on dipsacus asperoids seeds, realizing permeability improvement of seed coats through an ultrasonic generator, and activating endogenous growth factors of the seeds in combination with temperature gradient change; a multi-layer microporous floating plate is adopted to bear the pretreated seeds, the floating plate is placed in a seedling culture container, a nutrient solution is injected into the container, hydroponic seedling culture is carried out in a controlled environment, the floating plate is provided with different pore diameter layers to adapt to the seed development stage, and the nutrient solution comprises a plant growth regulator and a microelement combination; performing treatment before transplanting, namely performing physiological regulation treatment on root systems of the seedlings before transplanting, wherein the physiological regulation treatment comprises auxin induction and stress-resistant substance pretreatment. The invention aims to solve the problem that the subsequent field management cost is increased sharply due to poor field seedling emergence uniformity.

The invention belongs to the technical field of health-care wine, and particularly relates to waist-strengthening and kidney-tonifying wine which is prepared from morinda officinalis, cistanche deserticola, eucommia ulmoides, ginseng, cornu cervi pantotrichum slices, gecko, teasel, rhizoma drynariae, rock candy and 50-degree rice wine through related processing. The medicinal materials are ground and ultrasonically extracted, so that the dissolution of functional main components in the traditional Chinese medicine powder can be promoted, the soaking time of traditional Chinese medicines can be shortened, the content of effective components in the wine can be increased, and the wine not only can keep the flavor of the wine and has higher palatability, but also has the effects of tonifying the kidney, strengthening the waist and knees and improving the immunity. And the health-care tea is suitable for long-term drinking of middle-aged and elderly people with symptoms of waist and knee pain, frequent urination at night, physical weakness and low immunity.

The invention discloses a traditional Chinese medicine composition for treating bone diseases and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared by taking black monkshood, raw semen strychni, datura stramonium, dragon's blood and sappan wood as monarch drugs and taking ground beeltle, centipede, scorpio, Jin snake, zaocys dhumnade, black ant, teasel, rhizoma cibotii, native copper, rhizoma drynariae, radix achyranthis bidentatae, radix salviae miltiorrhizae, raw radix aconiti and the like as ministerial drugs; according to etiology and pathogenesis of bone diseases including cervical spondylosis, scapulohumeral periarthritis, rheumatic arthritis, hyperosteogeny and the like, medicines are reasonably combined, according to the etiology and pathogenesis, warm dredging and attacking evil are taken as main medicines, worm medicines are used for searching collaterals and eliminating evil are taken as essential medicines, the liver and kidney are tonified, the muscles and bones are strengthened, and the evil is prevented from hurting the body resistance; the traditional Chinese medicine can achieve the effects of warming channels and expelling cold, dispelling wind and eliminating dampness, activating meridians to stop pain, searching collaterals and eliminating evil, tonifying the liver and the kidney and the like, can effectively treat various orthopedic diseases, can treat symptoms by attacking evil and dredging collaterals, can treat root causes by tonifying the liver and the kidney, and achieves the purpose of treating both symptoms and root causes.

The present invention discloses a thin-layer identification method for Dipsaci Radix, Paeoniae Radix Rubra, and Notopterygii Rhizoma et Radix in Huoxue Antong Tincture. With the same test sample solution, three medicinal herbs, namely Dipsaci Radix, Paeoniae Radix Rubra, and Notopterygii Rhizoma et Radix in Huoxue Antong Tincture, can be simultaneously identified on one thin-layer plate. This method is simple, rapid, with a large amount of information, effectively improving the detection efficiency, reducing the test cost, having a short detection cycle, being accurate, reliable, with good reproducibility and high accuracy, and being able to effectively and comprehensively control the quality of Huoxue Antong Tincture.

The invention discloses traditional Chinese medicine granules for treating osteoporosis. The traditional Chinese medicine granules are prepared by extracting the following traditional Chinese medicine decoction pieces in parts by weight: 10-20 parts of rhizoma cimicifugae, 15-25 parts of astragalus membranaceus, 12-18 parts of bighead atractylodes rhizome, 10-20 parts of liquorice, 15-25 parts of salvia miltiorrhiza, 10-20 parts of ligusticum wallichii, 8-12 parts of corydalis tuber, 10-20 parts of leonurus, 10-20 parts of radix ophiopogonis, 15-25 parts of adenophora stricta, 5-10 parts of fritillaria, 12-18 parts of trichosanthes kirilowii maxim, 8-12 parts of teasel root, 10-20 parts of eucommia ulmoides and the like. The traditional Chinese medicine composition can be used for treating qi deficiency and blood stasis type osteoporosis and has the effect of regulating intestinal flora.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating ankylosing spondylitis and a preparation method thereof. The traditional Chinese medicine is prepared from the following raw materials: 6-18 g of fructus psoraleae, 6-20 g of herba epimedii, 3-15 g of radix aconiti lateralis preparata, 6-20 g of rhizoma drynariae, 9-18 g of radix achyranthis bidentatae, 12-24 g of dipsacus root, 6-12 g of radix clematidis, 10-30 g of garden balsam stem, 10-30 g of lycopodium clavatum, 9-15 g of radix paeoniae rubra, 6-12 g of native copper, 3-9 g of Chinese polyphaga, 6-12 g of roasted rhubarb, 6-15 g of notopterygium root, 6-15 g of radix angelicae pubescentis, 6-12 g of radix saposhnikoviae, 3-9 g of ephedra, 9-15 g of radix paeoniae alba, 6- The traditional Chinese medicine composition is prepared by adding and reducing cassia twig, Chinese herbaceous peony and rhizoma anemarrhenae decoction which are Jingui to be a little, the inflammatory response, bone destruction and pain symptoms of ankylosing spondylitis are accurately improved through the synergistic effect of multiple target points, and meanwhile, the preparation process is standardized to ensure the stable medicine effect.

The invention relates to the technical field of traditional Chinese medicine compound plasters, in particular to a traditional Chinese medicine compound plaster for treating meridian blocking type pain and numbness. Comprising the following components: 10 to 30 g of pseudo-ginseng, 10 to 25 g of lycopodium clavatum, 10 to 25 g of flos daturae, 10 to 30 g of radix clematidis, 10 to 20 g of ligusticum wallichii, 10 to 25 g of radix angelicae pubescentis, 10 to 30 g of angelica sinensis, 10 to 30 g of ginger, 10 to 30 g of radix salviae miltiorrhizae, 10 to 30 g of clove, 10 to 20 g of radix achyranthis bidentatae, 10 to 20 g of teasel root, 10 to 25 g of trogopterus dung, 10 to 25 g of safflower, 10 to 25 g of fenugreek, 10 to 30 g of fructus psoraleae, 10 to 25 g of dragon's blood, 10 to 30 g of corydalis tuber, 10 to 30 g of earthworm, 10 to 30 g of asarum, 10 to 25 g of frankincense, 10 The invention solves the problem that the damaged part is difficult to completely or mostly recover by the traditional treatment, and after the patient recovers, the recurrence probability is obviously reduced as long as the patient needs to pay attention to maintenance, a long-acting and stable treatment effect is provided for the patient, the burden of repeated treatment is relieved, the plaster covers the painful and numbness part after being heated, and the area of the plaster exceeds twice of that of the part, so that the curative effect is obvious. The medicine action range can be expanded, the damaged area is fully covered, and the treatment effect is improved.

This invention proposes a traditional Chinese medicine compound for treating ankylosing spondylitis of the kidney-deficiency and damp-heat type accompanied by gastrointestinal dysfunction, along with its preparation method, belonging to the field of traditional Chinese medicine technology. The compound consists of Smilax glabra, Bletilla striata, Paris polyphylla, Geranium wilfordii, Dioscorea hypoglauca, Patrinia scabiosaefolia, Dipsacus asper, Drynaria fortunei, Pyrola rotundifolia, Clematis chinensis, Pheretima aspergillum, Lycopodium clavatum, Corydalis yanhusuo, Paeonia lactiflora, Atractylodes macrocephala (fried), Coix lacryma-jobi (raw), Aucklandia lappa, and Glycyrrhiza uralensis. This invention combines these herbs to achieve a synergistic effect, collectively clearing heat and dampness, strengthening the spleen and kidneys, and unblocking the meridians. The overall formula addresses both strengthening the body's foundation and eliminating pathogenic factors, ensuring unobstructed meridian flow and relieving arthralgia. This compound has the functions of clearing heat and dampness, strengthening the spleen and kidneys, and unblocking the meridians. It offers a short treatment course, rapid efficacy, low recurrence rate after cure, few side effects, and is inexpensive and convenient to use for treating ankylosing spondylitis with gastrointestinal dysfunction.

The invention relates to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine ointment for rapid bone setting. The traditional Chinese medicine ointment is prepared from the following raw materials in parts by weight: 1 to 10 parts of semen strychni, 1 to 20 parts of herba lycopodii, 1 to 7 parts of catechu, 1 to 10 parts of myrrh, 1 to 5 parts of dragon's blood, 1 to 20 parts of garden balsam stem, 1 to 5 parts of radix aconiti agrestis, 1 to 8 parts of indigo naturalis, 1 to 5 parts of rhizoma kaempferiae, 1 to 10 parts of borneol, 1 to 8 parts of radix aconiti, 1 to 15 parts of frankincense, 1 to 25 parts of radix saposhnikoviae, 1 to 18 parts of radix dipsaci, 1 to 15 parts of rhizoma smilacis glabrae, 10 to 25 parts of rhizoma drynariae, 1 to 10 parts of musk and 2 to 5 parts of achyranthes aspera. The raw materials are processed and prepared into mixed medicine powder, sesame oil and minium are taken, the mass ratio of the sesame oil to the minium to the mixed medicine powder is 1: 1: 1, firstly, the sesame oil is put into a container to be heated, then the obtained mixed medicine powder is added, after uniform stirring, decoction is conducted for 30 seconds, flameout is conducted for natural cooling, then minium is put into the container, uniform stirring is conducted again, and the mixture in the container is oxidized to be dark. The ointment is suitable for traumatic injury and fracture swelling and pain, and can accelerate fracture healing and relieve local pain and swelling when being externally applied.

The invention relates to a medicine for endometrial cell senescence and a preparation process thereof, and belongs to the technical field of traditional Chinese medicine preparations. The medicine comprises the following traditional Chinese medicine components: 10-30 parts of semen cuscutae, 5-15 parts of herba taxilli, 5-15 parts of radix dipsaci, 5-15 parts of radix angelicae sinensis, 5-15 parts of radix scutellariae, 5-15 parts of radix paeoniae alba, 5-15 parts of rhizoma chuanxiong and 1-9 parts of rhizoma atractylodis macrocephalae, and has a remarkable curative effect on endometrial cell senescence in the implantation window phase of recurrent abortion. Pharmacodynamic experiments prove that the suppository prepared from the traditional Chinese medicine disclosed by the invention can be used for remarkably improving endometrial cell senescence, especially endometrial cell senescence in an implantation window stage (WOI) of recurrent abortion (URSA). The dosage form of the medicine can be suppositories, granules, capsules and the like, pharmacodynamic experiments prove that the same technical effect can be achieved, and the preparation is simple in preparation technology and suitable for further popularization and application.

The invention provides Chinese herbal medicine oil for improving body immunity, and relates to the technical field of traditional Chinese medicine preparation. The Chinese herbal medicine oil for improving body immunity comprises mint, girald daphne bark, centella asiatica, berchemia sinica, saffron crocus, flos rhododendri mollis, semen strychni, radix aconiti agrestis, vernonia graveolens, ginger, caulis spatholobi, rhizoma drynariae, angelica sinensis, radix aconiti, frankincense, myrrh, gastrodia elata, ligusticum wallichii, radix angelicae pubescentis, cortex acanthopanacis, codonopsis pilosula, radix clematidis, asarum, elecampane, rhizoma atractylodis macrocephalae and teasel. By following the compatibility principle of monarch, minister, assistant and guide in traditional Chinese medicine, the formula contains multiple medicinal materials capable of strongly expelling wind and removing cold and activating meridians to stop pain, and also contains medicinal materials capable of promoting blood circulation to remove blood stasis and tonifying liver and kidney, purgation and tonification are combined, both symptoms and root causes are treated, the pathogenesis of arthralgia is very accurate, the immunity of a human body can be improved, and by using the whole links of soaking, frying, filtering, squeezing and aging, the arthralgia treatment effect is improved. About 15%-20% of medicinal oil adsorbed in the medicinal materials can be recycled, the overall quality is improved, the properties of the medicinal materials can be fused through curing, the medicinal materials become mellow, and irritation is reduced.

The invention provides application of a dipsacus asper and radix cyathulae stem and leaf compound in a feed additive, and belongs to the technical field of feed. Dipsacus asper stem and leaf powder, radix cyathulae stem and leaf powder and corn flour are compounded, and the feed additive is prepared through double fermentation of bacillus subtilis and lactobacillus plantarum. The fatty acid synthase expression level of fattening pigs fed with the feed additive is remarkably reduced. The lean meat percentage of a control group is 62.75%, the lean meat percentage of a group fed with a conventional traditional Chinese medicine feed additive is 64.35%, the lean meat percentage of a group fed with a fermented traditional Chinese medicine feed additive is 67.87%, and the lean meat percentage is remarkably improved. The pig fattening period of the control group is 104 days, and the feed conversion ratio is 3.02: 1; the fattening period of the pigs fed with the conventional traditional Chinese medicine feed additive group is 101 days, and the feed conversion ratio is 2.94: 1; the fattening period of pigs fed with the fermented traditional Chinese medicine feed additive is shortened to 88 days, the feed conversion ratio is 2.57: 1, and the breeding efficiency is remarkably improved.

The invention discloses teasel glycosyl transferase and application thereof in production of alpha-hederaoside and teasel saponin B. The amino acid sequence of the teasel glycosyl transferase is shown as SEQ ID NO.1, and the nucleotide sequence of the coding gene of the teasel glycosyl transferase is shown as SEQ ID NO.2. The invention further discloses a preparation method of the teasel glycosyl transferase. After the glycosyl transferase is subjected to prokaryotic expression, a series of triterpenoid saponins can be catalyzed to be converted into triterpenoid saponin-3-(2-O)-glycoside products in a glycosylation manner, and the triterpenoid saponin-3-(2-O)-glycoside products comprise alpha-hederin and dipsacus asper saponin B. The discovery of the dipsacus asper triterpenoid saponin glycosyltransferase provides more optional biological elements for the biosynthesis of natural products, and has a good application prospect.

The invention discloses a traditional Chinese medicine composition for treating osteoarthritis, and belongs to the technical field of traditional Chinese medicines. In the traditional Chinese medicine composition, monarch drugs are radix angelicae pubescentis and processed semen strychni; ministerial drugs comprise radix aconiti preparata, tripterygium wilfordii, radix clematidis and rhizoma drynariae; the adjuvant drugs comprise kadsura pepper stem, liquidambar formosana hance, pawpaw, rhizoma dioscoreae nipponicae, frankincense, ground beetle, herba epimedii, teasel root, herba siegesbeckiae and lycopodium clavatum; and the conductant drug is coix seed. The whole formula is monarch, minister, assistant and guide, cooperates with each other, is rigorous in formula, has the effects of dispelling wind and eliminating dampness, warming channels and expelling cold, removing stasis and diminishing swelling, relaxing tendons and dredging collaterals, and tonifying kidney and strengthening liver, can remove arthralgia of knee and ankle joints and recover functions, can be used for treating osteoarthritis, and has a wide application prospect.

The invention discloses a novel application of a Guangkang capsule medicine. According to the application of the Gukang capsule medicine in preparation of the medicine for treating gout, the medicine for treating gout is a medicine preparation prepared from an extract obtained by mixing and decocting 570 g of roots of Japanese banana, 400 g of creeping oxalis, 600 g of fructus psoraleae and 300 g of radix dipsaci with water, 150 g of pseudo-ginseng fine powder, 30 g of fine powder of the roots of Japanese banana and pharmaceutically acceptable auxiliary materials. Animal experiments show that the serum uric acid level of a hyperuricemia model mouse can be remarkably reduced, and joint swelling and inflammatory cell infiltration are relieved. Clinical observation further proves that the traditional Chinese medicine composition has a good curative effect on improvement of arthralgia, limited activity and other symptoms of gout patients, is relatively high in safety and does not have obvious adverse reaction.

The invention belongs to the technical field of antibacterial products, and particularly relates to a traditional Chinese medicine probiotic anti-infection fermentation preparation and a preparation method and application thereof. The traditional Chinese medicine probiotic anti-infection fermentation preparation is sterilized fermentation liquor prepared from polygala tenuifolia, dipsacus asper, lactic acid bacteria and water. Before fermentation, the mass ratio of polygala tenuifolia, teasel and water is (10-20): (5-15): 1000, and the inoculation concentration of lactic acid bacteria is 108 / mL or above. A fermentation type antibacterial agent is prepared, components in polygala tenuifolia and dipsacus asper are subjected to metabolic recombination in the proliferation and metabolism process of lactic acid bacteria, the proportion of active components is adjusted, and finally the preparation with the antibacterial effect is formed.

The invention discloses a formula of a soaking solution for manual repairing and mounting of ancient calligraphy and paintings, and belongs to the technical field of protection and repairing of the ancient calligraphy and paintings. The soaking solution is prepared from the following raw materials in parts by weight: 1 part of spica prunellae, 1 to 4 parts of semen cassiae torae, 1 to 4 parts of fructus gleditsiae, 1 part of polygala tenuifolia, 1 part of periostracum cicadae, 1 to 4 parts of radix dipsaci, 1 part of sculellaria barbata, 1 part of rhizoma alismatis, 1 part of oyster, 1 part of bryozoatum, 0.5 part of liquorice root and a proper amount of root-free water. The soak solution formula for manual repairing and mounting of the ancient calligraphy and painting has the beneficial effects that the protection and repairing effects of the ancient calligraphy and painting can be remarkably improved. The formula has excellent decontamination and ink fixing performance, can effectively enhance the tensile strength and folding strength of paper, and meanwhile prevents the ink falling phenomenon of calligraphy and painting in the repairing process.

The application relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition, a traditional Chinese medicine preparation, a preparation method and application thereof. The traditional Chinese medicine composition contains angelica sinensis, safflower, red peony root, salvia miltiorrhiza, radix aconiti kusnezoffii, radix aconiti carmichaeli, cassia twig, drynaria, radix rubi sylvestris, frankincense, myrrh, radix rubi sylvestris, natural copper, elderberry, radix curdlane, crab shell and zhangdan. The preparation method of the traditional Chinese medicine preparation comprises the following steps: mixing angelica sinensis, safflower, red peony root, salvia miltiorrhiza, radix aconiti kusnezoffii, radix aconiti carmichaeli, cassia twig, drynaria, radix rubi sylvestris, radix rubi sylvestris, natural copper, elderberry, radix curdlane and crab shell with vegetable oil to perform frying and boiling, performing solid-liquid separation to obtain medicine oil; mixing the medicine oil after being refined with zhangdan, frankincense and myrrh to obtain an ointment; soaking the ointment in water, taking out, heating and melting, mixing with blood ointment powder, and spreading. The traditional Chinese medicine composition and the traditional Chinese medicine preparation have the effects of setting bone, continuing tendon and relieving swelling and pain.

The invention discloses a method for simultaneously detecting contents of various active ingredients in Sanbi decoction based on HPLC (High Performance Liquid Chromatography), and belongs to the technical field of analytical chemistry. The method for determining the content of loganic acid, gentiopicroside, 5-O-methylvisammioside, dipsacus asper saponin VI and glycyrrhizic acid in the Sanbi decoction is successfully constructed by virtue of an HPLC (High Performance Liquid Chromatography) gradient elution technology. A content determination result shows that in 15 batches of samples, the content ranges of the five active ingredients are respectively 1.6584 mg / g to 4.0230 mg / g, 1.1120 mg / g to 4.0518 mg / g, 0.1688 mg / g to 0.4344 mg / g, 2.7441 mg / g to 10.3693 mg / g and 2.6289 mg / g to 5.0324 mg / g. According to the Chinese herbal medicine compound preparation pharmaceutical research technical guidance principle (trial) managed according to the ancient classical famous prescription catalog, the content ranges all meet the standard requirement of the mean value + / -3SD. Moreover, the method provided by the invention has good accuracy and reliability, and a scientific basis can be provided for the quality control and evaluation of the substance standard of the Sanbi decoction.

The invention discloses a blood circulation promoting and blood stasis removing traditional Chinese medicine preparation for treating fracture and soft tissue injury, which comprises the following raw material medicines in parts by weight: respectively 10-15 parts of solid fruit, myrrh, frankincense, catechu, ground beetle, safflower, cynomorium songaricum, dipsacus root, borax, native copper, cortex albiziae and drynaria baronii; and 3-5 parts by weight of each of pseudo-ginseng and dragon's blood. Therefore, the traditional Chinese medicine composition can be used for treating fracture, traumatic injury, blood circulation promoting, blood stasis removing, swelling and pain relieving and sprain and strain.

The present invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for promoting the absorption of subchorionic hematoma in the early stage of pregnancy. The traditional Chinese medicine composition includes an oral medicine and an external patch. The external patch is prepared by grinding the following raw materials and mixing them with vinegar: Eucommia ulmoides, Boehmeria nivea root, Psoralea corylifolia, Artemisia argyi charcoal, Cassia obtusifolia, Rheum palmatum, Areca catechu, Foeniculum vulgare, Akebia quinata, Zanthoxylum bungeanum, Eugenia caryophyllata, Cinnamomum cassia, stir-fried Atractylodes macrocephala. The oral medicine is prepared by grinding the following raw materials: Cuscuta chinensis, Taxillus chinensis, Dipsacus asperoides, Colla Corii Asini, Anemarrhena asphodeloides, Phellodendron amurense, Dioscorea opposita, Paeonia lactiflora, Boehmeria nivea root, Eucommia ulmoides, Saposhnikovia divaricata, Cornus officinalis, Angelica sinensis, Rubia cordifolia, Agrimonia pilosa. The traditional Chinese medicine composition of the present invention includes an oral medicine and an external patch. The compatibility of the medicines is scientific and reasonable. The internal administration combined with external application has a significant therapeutic effect on the formation of hematoma caused by the downward aggregation of yin and blood to nourish the fetus after pregnancy, the more exuberant blood heat due to yin blood deficiency, the heat lurking in Chong and Ren meridians, the exuberant yang and blood heat, the overflow of blood due to heat, and the forced abnormal bleeding. It has the functions of stopping bleeding and preventing miscarriage.