36 results about "Indirect Pulp Capping" patented technology

Adhesive antimicrobial dental compositions and methods for forming and using compositions are disclosed. The compositions are primarily useful as pulp caps and dentin liners. The composition includes an alkyl methacrylate having an oxyphosphorus group, a polymerization initiator and an antimicrobial agent. The antimicrobial agent can be organohalogens, antibiotics, alkali metal hydroxides, alkaline earth metal oxides and alkaline earth metal hydroxides. The compositions have high dentin tensile bond strength, are stable as a single component or package system, can be polymerized in situ, prevent ingress by microorganisms into an area of a tooth treated with the compositions and can be syringe delivered.

Method of manufacturing dental restorations using curable compositions including degradable macromonomers having one or more terminal acrylate or methacrylate functionality, a curing composition, a filler composition including bioactive particles of bioactive glass, bioactive glass-ceramics, calcium phosphates, calcium apatites, or mixtures thereof and optionally one or more polymerizable acrylate or methacrylate comonomers. Degradable macromonomers are manufactured from cyclic monomers with compounds having acrylate or methacrylate functionality. Depending on their use, the degradable macromonomer compositions further include one or more organic or inorganic fillers, including a calcium-based compound and/or a radiopacity-imparting agent. The compositions are particularly suitable for root canal sealants, implants, bone cements, and pulp capping materials.

The invention discloses a method for regenerating a dental prosthetic material and an acidic amino acid-induced demineralized dental enamel outer enamel prism thereof in situ, and belongs to the technical field of in-situ regeneration of dental enamel outer enamel prisms. The preparation method is as follows: firstly, carrying out surface calcium activation onto a dental enamel surface, i.e., grafting calcium ions; then, forming calcium carbonate stable calcium ions step by step; finally, taking calcium carbonate stable calcium ions as foundation forms to synthesize hydroxyapatite crystals. Amino acid participates in the whole process, concentration of the amino acid added in a two-step process is consistent. The hydroxyapatite crystals deposited on the surface of the demineralized dental enamel are orderly and compact in sequence, and uniform in crystal morphology, so that obvious continued growth tendency of an artificial layer can be seen. The preparation method disclosed by the invention lowers protein extracting cost and harsh restrictions on an application environment, and is wide in prospect. The material prepared by the method disclosed by the invention can be applied to cosmetic dental for filling demineralization gaps, also can be used for repairing early-stage enamel demineralization, and can be used as a combined material for bottom pulp capping pit and fissure sealing, and the like.

The invention provides a pre-mixed calcium silicate/magnesium phosphate double-phase composite self-solidification root canal filling material and a preparation method and application thereof. Magnesium phosphate bone cement powder and at least one calcium silicate compound serve as the main phase, and at least one nonaqueous phase solvent capable of being mixed and dissolved with water and at least one injection-resistance material are added to prepare the root canal filling material with the excellent injectable performance. According to the pre-mixed calcium silicate/magnesium phosphate double-phase composite self-solidification root canal filling material and the preparation method and application thereof, the advantages of magnesium phosphate and calcium silicate materials are combined, so that the solidification time is short, the biological activity is good, and the marginal seal and anti-microbial characteristics are good; and meanwhile clinical application is convenient, and the root canal filling material can serve as the filling material for the field of dental department restoration such as pulp-capping and root canal therapy.

The invention discloses a bioglass-sodium alginate composite biomaterial, a kit and an application. The kit comprises two components: solid powder and a curing liquid, wherein the curing liquid is a phosphate buffer solution and the powder is calcium, phosphorus and silicon ternary bioglass micro-nanospheres, and the proportion of the solid powder to the curing liquid is 1.1-2.0g/mL. A paste blended by the solid powder and the curing liquid can be cured to form the composite biomaterial with certain mechanical strength and hard tissue repairing property. The biomaterial disclosed by the invention is simple in process equipment, easy to operate and low in cost. The prepared composite biomaterial has good bioactivity, degradation rate and certain mechanical strength and can be clinically used for common pulp capping treatment, oral cavity and orthopedic bone defect repair.

A kit for bonding to biological hard tissues, containing a phosphorylated polysaccharide, a polyvalent metal salt other than phosphates, and a solvent. The adhesive composition for biological hard tissues provided by the kit for bonding to biological hard tissues is suitably used in for medical uses, such as cement for bones or dental cement. In addition, since the adhesive composition has excellent bio-absorbability, it is useful as fusion materials for artificial joint prosthesis, fusion materials for spine fracture, fusion materials for extremity fracture, filling materials for bone tumors in the region of orthopedics, filling materials and restorative materials at dental caries-defective sites, luting materials for prosthetic restorative materials such as inlay and crown, pulp-capping and lining materials, implant surface treatment materials, periodontal disease therapeutic materials, hyperesthesia preventive materials, dental pulp capping materials, substrates for DDS, substrates for systems engineering, and tissue bonding materials in the dental region.

The invention provides a pulp capping agent for treating dental pulp lesions as well as a preparation method and application thereof. Bioactive particles release PO4<3-> ions in an oral environment topromote rapid deposition of Ca<2+> and PO4<3-> on the surface of the material, so that a mineralization layer is formed rapidly; the released metal ions and PO4<3-> play a neutralization role and thus the material has the stable pH value in the body fluid, so that the compatibility with the dental pulp cells is improved and the dental pulp cells are promoted to differentiate into the teeth. The dental pulp capping agent can be used in different ways based on different components. The pulp capping agent that is prepared by compounding of bioactive particles such as phosphosilicate glass, phosphosilicate ceramic and a restorative material causing polymerization covers the surfaces of teeth after being subjected to photo-induced polymerization and solidification, so that rapid formation of dental pulp and tooth tissues is induced and thus dental pulp lesions are treated. Moreover, the pulp capping agent prepared by including solid-phase powder and the liquid phase coats the surface of dental pulp uniformly to treat the dental pulp lesions.

The invention discloses a premixed magnesium phosphate-based dental filling material with stable suspension as well as a preparation method and application thereof. The dental filling material with excellent injectable property is prepared from magnesium oxide, at least one phosphate, as well as at least one non-aqueous phase solvent capable of being mixed and dissolved with the water and at leastone irradiation resistance material, wherein the magnesium oxide and the at least one phosphate are taken as main phases; the filling material further comprises at least one type of bioglass. The material maintains a liquid state under a sealing condition; after the material is padded into teeth and is in contact with physiological body fluid, the material is hydrated, solidified and hardened. The premixed magnesium phosphate-based dental filling material with stable suspension is prepared from a magnesium phosphate-based material due to the excellent biocompatibility and biological activityof the magnesium phosphate-based material; the premixed magnesium phosphate-based dental filling material serving as the filling material can be used in the fields of pulp capping, root canal therapy,dental restoration and the like.

The invention relates to dental pulp capping and pulp retaining paste, which is prepared from iodine glycerin, iodophor, phenocamphor, creosote and zinc oxide powder, wherein the volume ratio of the iodine glycerin: the iodophor: the phenocamphor: the creosote is (3 to 4):(1 to 2):(1 to 2):(3 to 4); the ratio of the creosote(mL): the zinc oxide powder (g) is 1:(4 to 6); all ingredients are mixed and are prepared into the paste, and thus the dental pulp capping and pulp retaining paste is obtained. The paste has the advantages that after dental pulp is exposed, the nerve burnt killing, the nerve removal and the root canal therapy are not needed; the whole tooth body with the tooth root becomes a dead tooth; the dental pulp capping and pulp retaining paste is directly smeared on the exposed surface of the dental pulp, hard hulls can be formed on the surfaces of dental pulp active body cells; the normal physiological function state of the tooth body is stably recovered; in addition, the treatment process time is shorter; the subsequent consultation times of a patient are fewer; the work intensity of oral doctors is reduced. The pulp capping and pulp retaining paste can be applied to the protection of tooth body dental pulp exposure positions.

The present invention provides a therapeutic agent for regenerating a dentin-pulp complex, containing a basic fibroblast growth factor and/or a homolog thereof as an active ingredient. The present invention also provides a pulp-capping agent containing a basic fibroblast growth factor and/or a homolog thereof as an active ingredient.

The invention relates to a tissue activity promotion type pulp capping agent and a preparation method thereof, and belongs to the technical field of pulp capping agents. Periploca forrestii Schltr isground and undergoes alcohol extraction, the obtained alcohol extract is collected and is concentrated, an ethyl acetate component is extracted from the Periploca forrestii Schltr, and the Periploca forrestii Schltr ethyl acetate part has strong osteoclast formation and bone resorption ability inhibition activity, and can improve the activity of cell tissues at the pulp capping position, so the tissue restoration condition is used is improved after the pulp capping agent. A pearl mother material is used as a powder main material, and the main components of the pearl mother powder main materialare calcium carbonate, organic matters and few trace elements, so the pulp capping agent is similar to human skeleton in chemical components and form structure, is nontoxic to local tissues or the whole body, has no rejection reaction, has good biocompatibility and bone affinity, can promote the restoration of root apex periphery tissues, guide the growth of alveolar bone cells and seal apical foramen, and has effectively improved restoration performance.

A method of direct pulp capping of a tooth including administering a dental composition comprising betamethasone and gentamicin onto an exposed pulp of a tooth, and covering the dental composition present on the tooth with a glass ionomer cement. The dental composition is administered in an amount effective to form a calcification over the exposed pulp. A dental composition having betamethasone, gentamicin, and optionally including a Portland cement. The dental composition is administered to an exposed pulp of a tooth to form a calcification over the exposed pulp.

The invention discloses application of paliurus ramosissimus or paliurus ramosissimus extract in preparation of a pulp capping material, and belongs to the field of medicine. According to the invention, a fresh paliurus ramosissimus product, a dry crushed paliurus ramosissimus product or the paliurus ramosissimus extract is taken as an active ingredient to serve as the pulp capping material, and the pulp capping material has stable and lasting anti-inflammatory performance, can promote hard tissue formation and improve dental pulp repair capacity, has an obvious effect and is better than clinical common control drugs, and therefore, technical problems that an existing pulp capping material is poor in anti-inflammatory performance and cannot be used for directly capping the pulp of the slightly-inflammatory dental pulp can be effectively solved.