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38 results about "Kushenin" patented technology
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Kushenin is a pterocarpan, a type of furano-isoflavonoid, found in Sophora flavescens.
Action of ferulic acid on enhancing drug effect of some medicaments and purpose thereof
InactiveCN101721400AOrganic active ingredientsPharmaceutical non-active ingredientsCatharanthineChemical reaction
The invention relates to an action of ferulic acid on enhancing the drug effect of some medicaments and a purpose thereof, wherein the medicaments mainly comprise alkaloid medicaments including matrine, kushenin, sophocarpine, hyoscyamine, narceine, hanfangchin A, jamaicin, morphine, codeine, evodiamine, strychnine, catharanthine, vincristine, taxol, verticine, peimine, peiminine, ephedrine, pseudoephedrine, wilfordine, triptolide, tripdiolide and the like, and flavonoid medicaments including puerarin, ginsenoside, ginsengenin, mangiferin, scutelloside, alkannin, meletin, rutin, hesperidin, daidzin, soybean isoflavone, daidzein, carthamin, catechin and the like. The ferulic acid and the medicaments can form a compound or a medicament compound, or the ferulic acid and the medicaments can generate a chemical reaction (including salification, esterification, amidation, ketonization, etherification and the like), and / or the ferulic acid and the medicaments can generate a synergistic effect and an additive effect.
Owner:QINGDAO QIYUAN BIO TECH CO LTD
Biological pesticide specially used for eggplants, and preparation method of biological pesticide
InactiveCN106342925AReduce consumptionEasy to operateBiocideDead animal preservationInsect pestPlant disease
The invention discloses a biological pesticide specially used for eggplants, and a preparation method of the biological pesticide, belonging to the technical field of crop pesticide preparation. The biological pesticide is mainly prepared from the following raw materials: radix sophorae flavescentis, cortex dictamni, broadleaf holly leaf, Chinese honeylocust spine, honeysuckle flower, herba menthae, folium eriobotryae, radix rehmanniae, folium artemisiae argyi, common nandina leaf, liquorice root, purslane herb, rhizoma menispermi and herba speranskiae tuberculatae. The biological pesticide contains multiple substances such as kushenin, dictamnine and polyphenols, thus not only having an inhibiting effect for multiple pathogenic bacteria, but also being capable of controlling pests such as aphids, Chinese chive maggots and red spiders and having a good promotion effect for all growth processes of the eggplants. Chemicals are not added into the biological pesticide specially used for the eggplants, so that the biological pesticide is safe and reliable in quality and environment-friendly; the biological pesticide is good in control effect for plant diseases and insect pests of the eggplants, simple and reasonable in preparation method, low in comprehensive cost, simple and flexible in use method and easy to popularize and apply.
Owner:蒋丽红
External healthcare product for promoting hair growth
The invention discloses an external healthcare product for promoting hair growth, which is characterized by being prepared by the following steps of: weighing 10-20g of total saponins of ginseng, 15-35g of astragaloside, 10-20g of glycyrrhizia polysaccharide, 15-45g of kushenin, 2-5g of capsaicin and 35-70g of total stilbeneglycoside of polygonum multiflorum respectively; sufficiently stirring and dissolving the components in 65-75% ethanol solution; standing for 12-24 hours; and filtering to obtain a liquid product. The external healthcare product disclosed by the invention can quickly promote hair growth in one month.
Owner:WUJIANG YISHENG TEXTILE
Bird repelling composition applicable to power transmission equipment
The invention belongs to the technical field of bird repelling of power transmission equipment, and particularly relates to a bird repelling composition applicable to power transmission equipment. The bird repelling composition is prepared from methyl anthranilate, kushenin, szechuan lovage rhizome, rheum officinale, water and auxiliary agents, wherein the auxiliary agents are lauryl sodium sulfate, glycerol and guar gum. The active ingredients are mixed, stirred, heated and dissolved to prepare an oil phase; the water and the auxiliary agents are uniformly mixed and stirred to prepare a water phase; the oil phase is slowly added into the water phase; the mixture is stirred, sheared and emulsified to obtain bird repelling micro-emulsion. When the kushenin, the szechuan lovage rhizome and the rheum officinale are applied to the bird repelling composition, a better flying bird repelling effect can be achieved. Particularly when the bird repelling composition is applied to the power transmission equipment, the transmission equipment can be prevented from being damaged by the bird repelling composition, and the birds can also be effectively prevented from gathering so as to achieve a bird repelling effect. The bird repelling composition has wide adaptation, can be applied to all kinds of power transmission equipment such as high-voltage transmission lines, power transformers and power transmission towers, and has an extremely obvious bird repelling effect.
Owner:STATE GRID CORP OF CHINA +2
Application of fenugreek biflavone glycosides for preparing anti-virus or/and anti-tumor drugs
ActiveCN101982171ASignificant anti-influenza virus effectExcellent anti-influenza effectOrganic active ingredientsOrganic chemistryAnti virusIn vivo
The invention provides an anti-virus or / and anti-tumor drug and a preparation method thereof and an application of fenugreek biflavone glycosides for preparing anti-virus or / and anti-tumor drugs. The invention provides the application of the chemical component fenugreek biflavone glycosides in fenugreek seeds as drugs for the first time, and uses the fenugreek biflavone glycosides for preparing anti-virus drugs and anti-tumor drugs for the first time. In vivo and in vitro experiment research shows that fenugreek biflavone glycoside tablets or fenugreek biflavone glycoside capsules of the invention have obvious effect on resisting influenza viruses, and the anti-influenza drug effect of the fenugreek biflavone glycoside tablets or fenugreek biflavone glycoside capsules of the invention is superior to the anti-influenza drug effect of the existing Western medicine ribavirin tablets. The anti-HBV effect of the fenugreek biflavone glycoside tablets or fenugreek biflavone glycoside capsules is superior to the anti-HBV effect of kurarinone capsules, and the anti-HIV effect of the fenugreek biflavone glycoside tablets or fenugreek biflavone glycoside capsules is superior to the anti-HIV effect of zidovudine tablets. The fenugreek biflavone glycoside tablets or fenugreek biflavone glycoside capsules have obvious effect on resisting proliferation of liver cancer, gastric cancer, intestinal cancer, lung cancer and cervical cancer cells, and the anti-tumor effect of the fenugreek biflavone glycoside tablets or fenugreek biflavone glycoside capsules is superior to the anti-tumor effect of the existing chemical component preparation hydroxycamptothecine injection.
Owner:XINJIANG INST OF MATERIA MEDICA
Application of pharmaceutical compositions in treatment of eczematous dermatitis
Disclosed are a pharmaceutical composition comprising kushenin and glycyrrhizic acid or derivatives thereof and the use of the composition in preparing a drug for preventing and treating dermatitis and eczema, wherein the weight ratio of the kushenin or a derivative thereof to the glycyrrhizic acid or a derivative thereof is 10:1-1:10.
Owner:施惠娟
Clotrimazole vaginal tablets
InactiveCN106420726AFine grainGood sustained releaseOrganic active ingredientsAntimycoticsPrillYeast vaginitis
The invention discloses clotrimazole vaginal tablets and a production method thereof. Raw materials and process parameters are optimized comprehensively, and it is unexpectedly found that the clotrimazole vaginal tablets have a good slow release effect, are not required to be combined with oral medication and have a good control effect on recurrence of recurrent vulvovaginal candidiasis under the optimized parameters. The method comprises steps as follows: (1) material preparation in parts by weight: (2) pretreatment: all raw and auxiliary materials, except kushenin powder and nano tourmaline powder, are sieved by an 80-mesh sieve for later use; the kushenin powder is sieved by a 200-mesh powder for later use; the particle size of the nano tourmaline powder is selected to range between 8 nm and 12 nm; (3) granulation: the raw and auxiliary materials are weighed according to a prescription, placed in a high-speed mixing granulator for mixing and subjected to wet granulation with a lactic acid aqueous solution; (4) drying: prepared wet granules are dried at 60 DEG C for 4 h; (5) granulation and whole mixing: dried granules are placed in a 3D motion mixer to be uniformly mixed as a batch; (6) tableting: tableting can be performed after the granules pass inspection, and each table contains 500 mg of clotrimazole.
Owner:ZHEJIANG SHENGBOKANG PHARMA CO LTD
Flavescent sophora root essence dispersion tablet
InactiveCN1557306APromote dissolutionGood dispersionOrganic active ingredientsDigestive systemLeukopeniaPharmaceutical Substances
The present invention relates to kurarinol dispersing tablet, and belongs to the field of medicine technology. The kurarinol dispersing tablet consists of kurarinol 1-65 wt%, disintegrating agent 2-90 wt%, lubricant and flow assistant 0-20 wt% and adhesive 0-20 wt%. The preparation process of the kurarinol dispersing tablet includes sieving the said components, mixing kurarinol and disintegrating agent, adding adhesive to form soft material, pelletizing, stoving, finishing, mixing with disintegrating agent, lubricant and flow assistant, measuring the content of kurarinol in pellet, weighing, and tablet pressing to obtain kurarinol dispersing tablet. The medicine may be taken after being dispersed in water, chewed or swallowed, and is used clinically in treating chronic viral hepatitis B, leucopenia caused by different reasons and allergic dermatosis. The medicine has the advantages of good dispersing state, high bioavailability, etc.
Owner:肖广常 +1
Natural antimicrobial preservative as well as production process thereof and hygienic product
ActiveCN103736139ANo side effectsSide effects, broad-spectrum bactericidal and antiviral broad-spectrumAbsorbent padsBandagesPreservativeAntibacterial activity
The invention discloses natural antimicrobial preservative. The natural antimicrobial preservative is prepared by the following substances in percentage by weight: 3-5% of tea tree hydrolat, 0.25-0.35% of kushenin, 0.8-1.2% of aloe vera juice, 0.15-0.25% of water soluble vitamin E acetate, and 93.2-95.8% of pure water. The natural antimicrobial preservative has the advantages of good antibacterial activity, long acting time, safety, no poison, high potential economic value and wide promotion and application foreground. The invention further discloses a production process of the natural antimicrobial preservative. The invention further discloses a hygienic product which is added with the natural antimicrobial preservative.
Owner:KINGDOM HEALTHCARE HLDG LTD GUANGDONG
Gynaecological gel containing moxa leaf essential oil and preparation method thereof
InactiveCN107375384AEnhance immune functionImprove antibacterial propertiesAerosol deliveryAntisepticsSide effectDamages tissue
The invention belongs to the field of medicine products and specifically relates to a gynaecological gel containing moxa leaf essential oil and a preparation method thereof. The gynaecological gel containing moxa leaf essential oil provided by the invention comprises the following components in parts by weight: 0.5-1 part of moxa leaf essential oil, 0.3-0.7 part of water-soluble chitosan iodine solution, 0.2-0.4 part of cnidium lactone, 0.1-0.3 part of kushenin, 1-3 parts of ethyl alcohol, 5-10 parts of glycerinum, 0.5-1.5 parts of carboxymethylcellulose, 0.001-0.1 part of borneol, 0.5-1 part of carbomer-940, 0.1-0.5 part of triethanolamine, 0.05-0.1 part of ethylparaben, 0.1-0.5 part of tween-80 and 85-95 parts of water. The gynaecological gel containing moxa leaf essential oil provided by the invention has the advantages of safety, no toxic or side effect, excellent adhesion, antisepsis and anti-inflammation effect, capability of promoting damaged tissue heal and high curative effect.
Owner:GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
Medication for treating cancer and chronic hepatitis B and its prepn. method
InactiveCN1480192AQuality is easy to controlActive ingredients are clearPowder deliveryDigestive systemCurative effectChronic hepatitis
A Chinese medicine for treating cancer and hepatitis B is prepared from astragalus root, ginseng and kurarnol. Its advantages are sure curative effect, quickly taking its effect and no toxic by-effect.
Owner:广东天之骄药物开发有限公司
Raw material composition and preparation method of a slow-release drought-resistant and water-retaining nutrient
The invention relates to a raw material composition and preparation method of a sustained-release drought-resistant water-retention nutrient. The drought-resistant water-retention nutrient provided by the invention is prepared from the following raw materials in parts by weight: 550-700 parts of HA35% ammonium phytate, 80-200 parts of N64% coated urea, 60-150 parts of P14 phosphate fertilizer, 60-150 parts of N17 and P44 ammonium phosphate, 20-35 parts of chitin, 3-30 parts of 80-mesh kushenin and 20-50 parts of glauconite. The sustained-release drought-resistant water-retention nutrient prepared by the preparation method provided by the invention has the characteristics of synchronous plant absorption and sustained release, high water absorption capability, good stress resistance and water retention properties, entire nutrients, rich bioactive substances and soil activation, can improve leaf photosynthesis, prevent bacteria infection and alleviate drought-induced plant physiological damage, has significant effects in greenness, environment friendliness and quality and efficiency improvement, is especially suitable for production of food economical crops, and has persistency and controllability on the drought resistance and nutrient supply.
Owner:武兴战
Medicine composition containing silymarin and kurainone or matrine and use thereof
The invention relates to the medicine field, in particular to a compound medicine combination which contains silybin and oxymatrine or matrine and the application of the combination for curing liver diseases, and more particularly relates to the application for curing diseases such as hepatitis, liver damage and liver cancer.
Owner:江苏盈科生物制药有限公司
Dry farming light, water, temperature and adaptability nutrient and preparation method thereof
InactiveCN104370647AResistImprove water absorptionAlkali orthophosphate fertiliserAmmonium orthophosphate fertilisersPhytic acidBiological activation
The invention belongs to the category of modern green agriculture and specifically relates to a dry farming light, water, temperature and adaptability nutrient and a preparation method thereof. The nutrient produced by the preparation method provided by the invention has the characteristics of high water absorption rate, good stress resistance and water retention capacity, effect of improving photosynthesis, strong temperature adaptability, full nutritional elements, rich bioactive substances and significant soil activation effect, is synchronous in plant uptake and sustained release and can improve the photosynthesis of leaf blades, prevent pathogen infection, absorb moisture and nutrients in air, relieve plant physiological injures caused by drought, unstable temperature and insufficient photosynthesis and effectively improve the quality of agricultural products. The dry farming light, water, temperature and adaptability nutrient is prepared from the following raw materials in parts by weight: 150-200 parts of lactic acid bacteria, 200-300 parts of bacillus, 450-600 parts of phytic acid, 100-150 parts of coating urea, 80-100 parts of a phosphate fertilizer, 15-30 parts of chitin, 80-120 parts of ammonium phosphate, 5-25 parts of kushenin and 10-18 parts of glauconite according to a certain method.
Owner:YANGLING HUAYUAN BIOTECH
Antitumor pharmaceutical composition and preparation method thereof
ActiveCN103977060AImprove KPS scoreImproved clinical symptom scoreOrganic active ingredientsAntineoplastic agentsLife qualityMedicine
The invention provides a preparation method of an antitumor pharmaceutical composition. The preparation method is characterized by comprising the following steps: selecting ginseng to prepare ginseng extractum, preparing the ginseng extractum into ginseng extract, preparing astragalus into astragalus extractum, preparing the astragalus extractum into astragalus extract, preparing the ginseng extract, the astragalus extract and kushenin into extractum, preparing the extractum obtained from the ginseng extract, the astragalus extract, and the kushenin into injection, sterilizing at a temperature of 100 DEG C for 30 minutes, carrying out lamp detecting and packaging to prepare a finished product of the antitumor pharmaceutical composition. The preparation method has reasonable flow, the obtained finished product has the advantages of high purity, good quality stability, scientific formula, extract curative effect, capability of significantly improving the KPS score, the clinical symptom score and the QOL score of a patient with advanced malignant tumor, reducing the weight loss, perfecting the living quality of the patient and relieving the clinical symptoms, and low occurrence rate of such adverse reactions as allergy.
Owner:CHANGBAISHAN PHARMA
An anti-tumor pharmaceutical composition and preparation method thereof
The invention relates to a medicinal composition and method for preparation, wherein the medicinal composition is prepared from astragalus root, gen-seng, flavescent sophora root through supersonic extracting, alcohol depositing, water depositing, formulating, loading and freeze-drying. The composition can be used for treating primary liver cancer, lung carcinoma, esophagus cancer, restocarcinoma, malignant lymphoma, gynaecologic carcinoma, leucopenia and chronic hepatitis B.
Owner:李东轩
Biopesticide for killing oncomelania
The invention discloses a biopesticide for killing oncomelania, which comprises the following materials in parts by weight: 35-64 parts of nicotine, 11-19 parts of celastrus angulatus, 10-16 parts of paraquat, 3-7 parts of sapium sebiferum, 15-20 parts of kushenin, 11-14 parts of santonin water aqua, 3-6 parts of fructus amomi, 10-12 parts of juglone, 25-36 parts of broad beans, 45-50 parts of ethanol, 5-11 parts of hirsutella thompsonii fisher powder and 35-40 parts of sanguinarine. The biopesticide disclosed by the invention has a good killing effect, and is quite obvious in function of killing oncomelania under a low concentration; and the biopesticide is low in toxicity to human, animals, aquatic plants and other aquatic animals, and is capable of relieving pollution to soil and water quality. The biopesticide disclosed by the invention is simple in formula, and easy and simple in preparation method.
Owner:QINGDAO JINXIU SHUIYUAN COMMERCE & TRADE
Novel medicine composition for treating hepatic diseases
InactiveCN1985988AFunction increaseAnti-hepatic fibrosisOrganic active ingredientsDigestive systemDiseaseHepatic lipase
The present invention belongs to the field of medicine technology, and is especially a kind of medicine composition and its preparation process. The medicine composition is prepared with kurarinone 4-400 weight portions, glutathione 3-300 weight portions, and tiopronin 1-100 weight portions. The medicine composition may be prepared into different pharmaceutically acceptable forms, preferably injection and oral preparation. It has the pharmacological activities of antagonizing virus, improving liver cell function, antagonizing liver fibrosis, regulating immunity, diminishing inflammation, etc. and may be used in treating various hepatic diseases, viral hepatosis, medicinal hepatosis, alcoholic hepatosis, etc.
Owner:海安江理工技术转移中心有限公司
Complex salt consisting of glucuronic acid or glucurolactone and kushenin or matrine and application thereof
The invention relates to the medicament field, in particular to a complex salt consisting of glucuronic acid or glucurolactone and kushenin and / or matrine, a method for preparing the complex salt, application of the complex salt in treating liver diseases, in particular the diseases such as hepatitis, hepatic injury, liver cancer and the like, and a complex salt medicament capable of being used as an oral administration dosage form as well as a non-oral administration dosage form. Pharmacodynamic laboratory science for comparing the complex salt with the glucurolactone, sodium glucuronate, the kushenin and the matrine shows that the functions of the complex salt are better than that of using the glucurolactone, the sodium glucuronate, the kushenin and the matrine independently. The enhancement action is proved on a plurality of animal models.
Owner:刘兆平
Pharmaceutical composition for treating gynecological diseases
InactiveCN101579338AEffective treatmentTreatment safetyOrganic active ingredientsSexual disorderDiseaseTraditional medicine
The invention discloses a traditional Chinese medicine pharmaceutical composition for treating gynecological diseases, which is characterized by comprising 1-100 of kushenin and 1-50 of scutelloside according to the parts by weight, wherein 50 of the kushenin and 25 of the scutelloside are adopted according to the parts by weight. Pharmacological research shows that the pharmaceutical composition has certain actions for resisting bacteria, resisting inflammatory, relieving itching and resisting colpitis and provides an effectively pharmacological foundation for treating colpitis and cervicitis.
Owner:北京卓越同舟药物研究院有限公司
Raw material composition and preparation method of sustained-release drought-resistant water-retention nutrient
The invention relates to a raw material composition and preparation method of a sustained-release drought-resistant water-retention nutrient. The drought-resistant water-retention nutrient provided by the invention is prepared from the following raw materials in parts by weight: 550-700 parts of HA35% ammonium phytate, 80-200 parts of N64% coated urea, 60-150 parts of P14 phosphate fertilizer, 60-150 parts of N17 and P44 ammonium phosphate, 20-35 parts of chitin, 3-30 parts of 80-mesh kushenin and 20-50 parts of glauconite. The sustained-release drought-resistant water-retention nutrient prepared by the preparation method provided by the invention has the characteristics of synchronous plant absorption and sustained release, high water absorption capability, good stress resistance and water retention properties, entire nutrients, rich bioactive substances and soil activation, can improve leaf photosynthesis, prevent bacteria infection and alleviate drought-induced plant physiological damage, has significant effects in greenness, environment friendliness and quality and efficiency improvement, is especially suitable for production of food economical crops, and has persistency and controllability on the drought resistance and nutrient supply.
Owner:武兴战
Application of pharmaceutical compositions in preparation of drugs for treating sterile pustular dermatosis
ActiveCN105267227AOrganic active ingredientsAntipyreticPalmoplantar pustulosisPharmaceutical medicine
The invention relates to kushenin (oxymatrine and matrine) and glycyrrhizic acid or their pharmaceutically acceptable forms or derivatives and a kit containing the compositions, also relates to matrine glycyrrhizate and kushenin glycyrrhizate, and discloses an application of the compositions in preparation of drugs for preventing and treating sterile pustular dermatosis (comprising impetigo herpetiformis, acrodermatitis continua, palmoplantar pustulosis, subcorneal lpustular dermatosis, and eosinophilic pustular folliculitis).
Owner:施惠娟
Mutual transformation method of functional components of radix sophorae flavescentis
The invention discloses a mutual transformation method of functional components of radix sophorae flavescentis. The functional components comprise matrine and kushenin. The method comprises the following steps: by taking radix sophorae flavescentis as a raw material, extracting with pure water, carrying out alcohol precipitation, and extracting to obtain a mixture of matrine and kushenin; the obtained matrine and kushenin mixture is oxidized with an oxidizing agent, so that matrine is oxidized into kushenin, then neutral aluminum oxide is used for chromatography, and high-purity kushenin is obtained; and / or reducing the kushenin into the matrine by using a reducing agent in the obtained matrine and kushenin mixture, and then performing chromatography by using neutral aluminum oxide to obtain the high-purity matrine. By using the method disclosed by the invention, the mutual transformation of the matrine and the kushenin can be completed according to actual requirements, and the matrine and the kushenin with high purity can be prepared. The invention provides an effective technical means for extraction and preparation of functional components of sophora flavescens.
Owner:西安岳达生物科技股份有限公司
Application of a pharmaceutical composition as a medicine for preparing and treating aseptic pustular dermatosis
The invention relates to kushenin (oxymatrine and matrine) and glycyrrhizic acid or their pharmaceutically acceptable forms or derivatives and a kit containing the compositions, also relates to matrine glycyrrhizate and kushenin glycyrrhizate, and discloses an application of the compositions in preparation of drugs for preventing and treating sterile pustular dermatosis (comprising impetigo herpetiformis, acrodermatitis continua, palmoplantar pustulosis, subcorneal lpustular dermatosis, and eosinophilic pustular folliculitis).
Owner:施惠娟
Combination including isoglycyrrhizinate and oxymatrine and the purpose thereof
ActiveCN101062047BLow acute toxicityImprove protectionOrganic active ingredientsDigestive systemDiseaseOxymatrine
The invention provides a medicinal composition which comprises kurarinone or its derivatives and isoglycyrrhizinic acid or its derivatives. The invention also provides the use of the pharmaceutical composition in treating acute and chronic hepatitis and related diseases. the invention also provides various dosage forms of the pharmaceutical composition.
Owner:CHIA TAI TIANQING PHARMA GRP CO LTD
Combination including isoglycyrrhizinate and oxymatrine and the purpose thereof
ActiveCN101062047ALow acute toxicityImprove protectionOrganic active ingredientsDigestive systemDiseaseOxymatrine
The invention provides a medicinal composition which comprises kurarinone or its derivatives and isoglycyrrhizinic acid or its derivatives. The invention also provides the use of the pharmaceutical composition in treating acute and chronic hepatitis and related diseases. the invention also provides various dosage forms of the pharmaceutical composition.
Owner:CHIA TAI TIANQING PHARMA GRP CO LTD
Application of fenugreek biflavone glycosides for preparing anti-virus or/and anti-tumor drugs
Owner:XINJIANG INST OF MATERIA MEDICA
Application of a drug combination as a drug for the preparation of drugs for the treatment of neuropsychiatric disorders and skin diseases
The invention relates to kushenin (oxymatrine, matrine and isomatrine) and glycyrrhizic acid or their pharmaceutically acceptable forms or derivatives and a kit containing the compositions, and also relates to matrine glycyrrhizate and kushenin glycyrrhizate. The invention discloses an application of the compositions in preparation of drugs for preventing and treating neuropsychic disturbance dermatosis (pruritus, lichen simplex chronicus, prurigo, nodular prurigo, prurigo pigmentosa and lichenoid dermatitis).
Owner:施惠娟
Kushenin tablet and preparation method thereof
ActiveCN114191403AStable and long-acting drug releaseStable drug releaseAntibacterial agentsOrganic active ingredientsPharmaceutical medicinePharmaceutical Aids
The present invention discloses a kushenin tablet and a preparation method thereof, the kushenin tablet comprises kushenin, a sustained-release material, glucan, a filler, a flow aid, a lubricant, a disintegrating agent and pharmaceutically acceptable auxiliary materials, the particle size D90 of the kushenin is more than or equal to 100 [mu] m and less than or equal to 150 [mu] m, and the mass ratio of the kushenin to the sustained-release material to the glucan is 1: 0.05-0.1: 0.1-0.2. The mass ratio of the flow aid to the lubricant is (1-4): 1. The product disclosed by the invention has the advantages of stable and long-acting drug release, no sticking, tablet cracking and other phenomena in the tabletting process, qualified content uniformity, qualified and stable product quality, simple process operation and high application value, and is suitable for commercial large-scale production.
Owner:广东逸舒制药股份有限公司 +2
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