67 results about "Previtamin D3" patented technology

An oil composition containing 25-hydroxy Vitamin D₃ and an oil is provided. In addition an emulsion, a microencapsulated oil composition, and a feed premix composition each containing 25-hydroxy Vitamin D₃ are provided. Methods of making an oil composition, a microencapsulated oil composition, and a feed premix containing 25-hydroxy Vitamin D₃ are also provided.

An oral dosage form comprising a single dose of 25-hydroxy-vitamin D₃ sufficient to elevate the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml for at least 7 days and a pharmaceutically suitable oral carrier system, wherein subsequent single doses at least every 7 days are sufficient to sustain the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml at steady-state pharmacokinetics is disclosed. A method of elevating and sustaining the blood level concentration of 25-hydroxy-vitamin D₃ in a human in need thereof comprising orally administering or parenterally administering by injection or infusion, at least once every 7 days, a single dose of 25-hydroxy-vitamin D₃ sufficient to elevate the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml for at least 7 days, wherein the single doses orally administered at least every 7 days are sufficient to sustain the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml at steady-state pharmacokinetics is disclosed. The human in need thereof may be a human deficient in vitamin D having a serum level concentration of 25-hydroxy-vitamin D₃ less than 30 ng/ml.

We disclose the use of 25-OH D3 (calcifediol) to increase muscle strength, muscle function, or both. Vitamin D3 (cholecalciferol) may optionally be used together with 25-OH D3. Forms and dosages of a pharmaceutical composition, as well as processes for manufacturing medicaments, are also disclosed.

A formulation of supplement is able to boost the natural cells, both increasing the population of the natural cells and enhancing the natural cell's activity. The formulation can be administered via different forms, such as tablet, injection, skin absorption and etc. This formulation comprises 16 different components, including Alpha Lipoic Acid, Arabinoxylin, Curcumin, Garlic, Genistein, Ginseng, Lentinan, Mistletoe, N-Acetylcysteine, Resveratrol, Selenium, Vitamin B Complex, Vitamin C, Vitamin D3, Vitamin E and Zinc. By virtue of enhancing the natural killer cells (NKC) in the body, the formation is helpful for the prevention and treatment of a number of different human or animal diseases, such as cancers and viral infections. In addition, certain synergistic effects have been observed between different components in the formulation, which further enhances the beneficial effect of the formulation.

The invention discloses a photochemical reaction device and a method for synthesizing vitamin D3 by using narrowed high-voltage mercury lamp wavelength and one- step optical isomerism, relating to a vitamin D3. It comprises container, internal pipe, mercury vapour lamp, mediolateral jacket and collecting bottle, the mercury vapour lamp is installed in internal pipe, external jacket is set inside of internal pipe, internal jacket is installed outside of internal pipe, internal jacket is installed between internal tubular lamp and external jacket, the irradiation liquid export of container is connected with collecting bottle. Said method comprises following steps: preparing 7- desmesterol solution and dissloving it in ethanol; evacuating and ventilating nitrogen gas, preparing solution with sodium tungstate or acetate of lead, feeding it into external jacket as filtering liquid, preparing solution with cobalt sulfate, nickel sulfate, sulphuric acid and water, feeding it into internal jacket as filtering liquid, feeding 7- desmesterol solution from feed inlet through condenser circulation for photochemical reaction, ventilating nitrogen gas from feed inlet to mix with 7- desmesterol solution, discharging solution after photochemical process into collecting bottle.

The invention relates to a fluorescent lamp, preferably a low pressure mercury discharge lamp for stimulating previtamin D3 production. The lamp has a discharge tube with a discharge gas filling. The inside wall of the discharge tube is covered with a phosphor coating for converting short wave UV radiation of the ionized discharge gas into longer wave UV radiation. The discharge tube is closed at both ends and provided with electrodes which are held and lead through a base cap at both ends. The base caps of the lamp are provided with contact pins for connecting the lamp to an electrical power supply.

According to the improvement of the invention the UV light radiating coating of the discharge tube comprises

• • a first phosphor for emitting light waves in the UVB spectrum and
  • a second phosphor for emitting light waves in the visible light spectrum and for suppressing the emitted light in the UVB spectrum.

The invention relates to compound vitamin nanoemulsion belonging to the technical field of pharmacy. Every 1000 ml of nanoemulsion is prepared by the method comprising the following steps of: fully mixing 35-50g of AEO-9 or AEO-4, 150-200g of tween-80, 16-22g of phenylcarbinol and fat-soluble active ingredients at 30-60 DEG C to prepare an oil phase; adding water to dilute the oil phase; adding water-soluble active ingredients; evenly mixing; adding water to dilute and confirm solution contents and adding water to dilute to a volume, wherein the fat-soluble active ingredients comprise 6-18 million IU of vitamin A, 1.8-4.8 million IU of vitamin D3 and 2.5-7.5g of vitamin E, and the water-soluble active ingredients comprise 1-4g of vitamin B1, 0.2-1.0g of vitamin B2, 1.6-4.2g of vitamin B6, 5-25g of barberry extractive and 30-60g of amino acid. The product is clear and transparent, has good stability, slow-release effect, persistent drug effect, great specific surface area of nanoemulsion particles and good system compatibility, can obviously improve the drug absorption rate and the bioavailability and can be compounded with various useful elements besides vitamins.

The invention discloses a chromatographic method for rapidly measuring the content of vitamin D3, namely a method for measuring the content of vitamin D3 by using high performance liquid chromatography (HPLC); and the content of vitamin D3 in a sample containing complex components can be measured rapidly and accurately by smartly optimizing chromatographic conditions. The chromatographic method disclosed by the invention comprises the following steps: (1), preparing a reference solution; (2), processing the sample; and (3), setting liquid chromatographic conditions, wherein a chromatographic column and a silica gel column are set to 50*4.6 mm and 2.7 microns; the flow velocity is set to 2 ml/min; a mobile phase is prepared by uniformly mixing isopropanol with normal hexane according to the volume ratio of 0.5:99.5; the detection wavelength is set to 264 nm; and the sampling amount is set to 75 microliter. The chromatographic method disclosed by the invention is capable of measuring the content of vitamin D3 simply, conveniently, rapidly and accurately; the analysis time is shortened; the use amount of solvents is reduced; and the analysis cost is reduced.

The invention discloses a photochemical synthesis method of 25-hydroxy vitamin D3. The photochemical synthesis method comprises the following steps of: dissolving 25-hydroxy-7-dehydrocholesterol in a mixed solvent system containing a polar solvent and a non-polar solvent, and adding an antioxidant to react under the illumination; separating and recovering the 25-hydroxy-7-dehydrocholesterol after reacting; and heating to isomerize reactants retained after the 25-hydroxy-7-dehydrocholesterol is separated, and then freezing the isomerized reactants to recrystalize to obtain 25-hydroxy vitamin D3 crystals. The photochemical synthesis method disclosed by the invention has the main advantages that the conversion rate of 25-hydroxy-7-dehydrocholesterol open-loop under each time of illumination is below 40 percent through controlling the reactant concentration and the illumination time, and the 25-hydroxy vitamin D3 crystals with the purity of being more than 99 percent can be obtained without column chromatography isolation in the purifying process; and the photochemical synthesis method disclosed by the invention is simple in production process, improved in utilization efficiency of raw materials, saved in cost and suitable for large-scale production.

The invention provides a new industrial method for producing vitamin D3 by taking wool fat as a raw material. The new industrial method comprises the following steps: carrying out saponification and primary purification on the wool fat in a low alcohol solution, thus obtaining a cholesterol crude product; directly carrying out acetylation on the cholesterol crude product, thus obtaining high-purity cholesterol acetate; then sequentially carrying out oxidizing, hydrazone forming, hydrazone removing, hydrolyzing, illuminating and the like, thus obtaining the vitamin D3. A production technology disclosed by the invention is efficient, green and environment-friendly, is high in product yield and is suitable for industrial production, and the manufacturing cost of the vitamin D3 is greatly reduced; a saponification technology is ingenious in filtrate treatment, has no generation of waste liquid and waste and is more beneficial for environment protection.

We disclose compositions comprising Vitamin D (cholecalciferol and/or ergocalciferol) and 25-OH D3 (calcifediol), and use of those compositions to affect at least concentration, bioavailability, metabolism, or efficacy of vitamin D in a human. Forms and dosages of the composition, as well as processes for manufacturing a spray-dried formulation, are also disclosed.

The invention discloses sodium selenite vitamin injection and a preparation method thereof and belongs to the technology of veterinary medicaments. The vitamin injection is water-soluble injection which is prepared from active ingredients of vitamin A, vitamin D3, vitamin E and sodium selenite through a solubilizer Tween, span, polyoxyethylenated castor oil (35), a preservative 2, and 6-ditertiary butyl paracresol. The sodium selenite vitamin injection has the effects of improving the nutritional conditions of cows, enhancing the cow body physique, accelerating the oestrous period, improving the artificial fertilization and conception rate, preventing hysteritis and retained fetal membranes of the cows, promoting healthy development of calves, and preventing white muscle disease of the calves.

The invention provides a pudding-vitamin D3 mixed nutrient solution capable of alleviating anaemia and a preparation method thereof. The preparation method comprises the following steps: 1) mixing water and pudding powder according to a ratio of 10: 1 under stirring and carrying out boiling for 10 to 15 min; 2) mixing pawpaw powder, blueberry juice and water according to a ratio of 1: 1: 4 under stirring; 3) pouring a mixed liquid prepared in the step 2) into a mixed liquid prepared in the step 1); 4) cooling a mixture prepared in the step 3) at normal temperature; 5) acquiring pudding; 6) heating the pudding to 100 DEG C, maintaining the pudding at a temperature of 80 to 90 DEG C for 20 min, adding rice, cassia bark, haw pulp, dried towel gourd and raw rehmannia root, adding 5 to 6 g of black tea every 2 to 5 min until all the black tea is added, carrying out filtering with a 200-mesh sieve and taking a liquid; and 7) mixing the liquid obtained in the step 6) with vitamin D3 so as to obtain the nutrient solution. The pudding-vitamin D3 mixed nutrient solution provided by the invention has diversified and unique taste and meets requirements of people for cate; the preparation method is simple, has low cost and is beneficial for improvement of economic benefits; and after long-term usage of the mixed nutrient solution, good effect can be obtained.

The invention discloses a method for separating vitamin D3 from tachysterol T3. According to the method, high-purity vitamin D3 and tachysterol T3 are efficiently separated from a mixture containing the vitamin D3 and the tachysterol T3 by a fractional extraction method, wherein a medium polar to polar organic solvent, ionic liquid or a binary mixed solvent consisting of the ionic liquid and the medium polar to polar organic solvent serves as an extracting agent. The method has the advantages of high separation efficiency, low solvent consumption, high yield, safety, environmental friendliness, easiness in industrialized production and the like.

The invention belongs to the field of healthcare product medicine and particularly relates to a multivitamin and a preparing method thereof. Vitamin A, vitamin B, vitamin B2, vitamin B6, vitamin B1, vitamin C, vitamin D3, vitamin E, biotin, folic acid, nicotinamide, calcium pantothenate, Ca, Mg, P, Cu, Fe, K, Mn and Zn are evenly mixed and screened by a 90-mesh screen; mannitol with the weight parts equal to the sum of the weight parts of the aforementioned mineral substances and the weight parts of the aforementioned microelements and olive oil with the weight parts equal to a half of the sum of the weight parts of the aforementioned mineral substances and the weight parts of the aforementioned microelements are added and mixed; and then, the multivitamin can be obtained through pelletizing, drying and tabletting. The active ingredients such as the vitamins, the mineral substances and the microelements in the multivitamin are substances necessary for a human body and are widely distributed in all the parts of the human body, and the level of the microelement nutrient substances in tissue and plasma is in steady-state regulation; the multivitamin can be used for healthcare purposes, can also improve the resistance of the human body, and is free of toxic and side effects.

The therapeutic ultrasound gel is a composition that lubricates the abdomen for ultrasound scanning, that enhances the transmission of sound waves during ultrasound diagnostic imaging, and that has beneficial therapeutic effects in preventing the formation of stretch marks. The composition contains effective amounts of aloe vera (Aloe barbadensis), glycerin, and various agents for preventing the formation of stretch marks, with the balance being sufficient water to adjust the consistency of the composition. The composition may also be formulated for home use, chiefly by the addition of vitamin D3 or, alternatively, vitamin K. Either formulation may contain additional excipients, including surfactants, emulsifiers, humectants, stabilizers, thickeners, pH balancers, preservatives, colorants, and scent, if desired.

The present invention belongs to the technical field of analysis and detection, in particular to a simultaneous and rapid determination method of vitamin A, vitamin D<3> and vitamin E. The method comprises the following steps: (1) vitamin A, vitamin D<3> and vitamin E in a sample to be tested are extracted with dimethyl sulfoxide; and the obtained extraction liquid is oscillated and extracted withn-hexane, concentrated and redissolved to obtain a sample solution; (2) standard solutions of vitamin A, vitamin D<3> and vitamin E are prepared; and multiple standard series of solutions are prepared according to the concentration gradient; (3) the sample solution and the standard solutions are detected and analyzed with the high performance liquid chromatography; and the contents of vitamin A,vitamin D<3> and vitamin E are determined with an external standard method. With the method, simultaneous determination of vitamin A, vitamin D<3> and vitamin E is realized; the pretreatment time of the sample is greatly shortened; the work efficiency is improved; at the same time, the detection accuracy is improved; and the laboratory cost is reduced.

The invention belongs to the technical field of health care product, and especially relates to a vitamin mineral matter tablet, and a preparation method thereof. The vitamin mineral matter tablet is mainly composed of a tablet core and a film coating agent; the tablet core comprises, by weight, at least one or a plurality of metals selected from iron, magnesium, zinc, and calcium, at least one vitamin or a plurality of vitamins selected from vitamin C, vitamin C sodium, vitamin E, vitamin A, vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamin B6, vitamin B12, vitamin D3, vitamin K, folic acid, and vitamin H; and an auxiliary agent; and the mass amount of the vitamin C sodium accounts for 40 to 100% of the total mass amount of vitamin C and vitamin C sodium. The vitamin mineral matter tablet is capable of solving problems in the prior art that conventional vitamin mineral matter tablet is poor in stability, chemical interacting effect is easily caused, efficiency is influenced, andcomposition yellowing or generation of black spots is caused.

The invention relates to the technical field of analysis of functional components in health food, in particular to a method for measuring vitamin D3 in soybean protein powder. The method comprises thesteps of saponifying, extracting, washing, concentrating, purifying and carrying out high performance liquid chromatography, wherein the step of purifying comprises the processes of sequentially carrying out activation, balancing, sample loading, leaching and elution on a silica gel solid phase extraction column by using chemical methods. Impurities are firstly removed by means of the step of leaching, and the vitamin D3 is completely dissolved and eluted by means of the step of elution, so that all the vitamin D3 in a sample to be measured can be obtained only by collecting eluate, and the amount of the vitamin D3 can be accurately controlled. Compared with the prior art, the improved purifying step of the method is very simple, accurate and easy to operate, and the detection cost is greatly lowered, so that the method has wide market application prospect.

The invention relates to a CaCO3 vitamin D3 preparation and a preparation method thereof. The CaCO3 vitamin D3 preparation is mainly prepared from coated pills, wherein the coated pill includes a pillcore, a medicine coating layer and a protective coating layer; the medicine coating layer and the protective coating layer successively coat the pill core. The pill core includes: CaCO3, a disintegrating agent, filler and a binder; the medicine coating layer includes: vitamin D3 and a binder; the protective coating layer is mainly prepared from coating powder. By dispersing the CaCO3 in the pillcore, containing the disintegrating agent and filler, of the coated pill and dispersing the vitamin D3 in the medicine coating layer coating the pill core, and binding the pill core with the medicinecoating layer through the binder and coating the pill with the protective coating layer, a problem of degradability of vitamin D3 is avoided, and uniformity of the CaCO3 and vitamin D3 is increased and stability of the vitamin D3 is improved.