The invention belongs to the technical field of a tag labeling device, and particularly relates to a full-automatic TSA (Transportation Security Administration) tag labeling machine. The full-automatic TSA tag labeling machine comprises a stander, and a tag storage box, a tag sucker assembly, a tag adsorption and detection platform, a product storage conveyor belt, a product sucker assembly, a product positioning fixture assembly, a labeling sucker assembly, a product fixture transport system, a first vision system and a second vision system, which are respectively arranged on the stander. Compared with the prior art, the full-automatic TSA tag labeling machine has the following advantages: the labeling speed is high, error in labeling is avoided, firmness in labeling is realized, miss in labeling is avoided; moreover, after the tag is automatically labeled, the detection is not needed; meanwhile, the full-automatic TSA tag labeling machine can be connected with a full-automatic packaging machine, so that after the tag is labeled, a lock can be automatically sent into the packaging machine, the complete automation of labeling, detection and packaging can be realized, and the total productivity can be improved by 10 times or more.