31 results about "Prosthesis Loosenings" patented technology

Systems for bone and spinal stabilization, fixation and repair include intramedullar nails, intervertebral cages and prostheses, remotely activatable prostheses, tissue extraction devices, and electrocautery probes. The intramedullar nails, intervertebral cages and prostheses, are designed for expansion from a small diameter for insertion into place to a larger diameter which stabilizes, fixates or repairs the bone, and further can be inserted percutaneously. Remotely activatable prostheses can be activated from an external unit to expand and treat prosthesis loosening. Tissue extraction devices, and electrocautery probes are used to remove tissue from desired areas.

The invention discloses a positioning and navigation system. The positioning and navigation system is used for leading a prosthesis to be implanted into acetabular fossa. The positioning and navigation system comprises a positioning base and a positioner, wherein the positioning base comprises a jointing base and a guide rod, the jointing base cooperates with the acetabular fossa to be jointed tothe acetabular fossa for fixation; the guide rod is fixed to the jointing base and is coaxial with the acetabular fossa; the positioner comprises a sleeve and a guide arm which is formed in a manner that the sleeve extends, the sleeve is suitable for sleeving of the guide rod, and a plurality of guide holes being parallel to the axis of the sleeve are formed in the guide arm; and the guide holes are suitable for positioning needles in a manner of beating in, so that the positioning needles can be beaten into the outer region of the acetabular fossa and are parallel with the axis of the acetabular fossa. The invention further discloses a prosthesis implantation method. The positioning and navigation system can accurately position the milling and softening direction of the acetabular fossa and the implantation position of an acetabular cup, so that during operation, the acetabular cup can be accurately implanted, the acetabular cup can be guaranteed to be implanted to the best position,and the incidence rate of complications of prosthesis dislocation, prosthesis loosening, pain and the like can be reduced.

The invention provides an assembly type shoulder joint prosthesis and a manufacturing method thereof. The assembly type shoulder joint prosthesis comprises a scapula prosthesis, a glenoid cavity prosthesis and a humerus prosthesis, wherein the free end of a glenoid cavity supporting rod of the glenoid cavity prosthesis is in movable pivot connection with a glenoid cavity part of the scapula prosthesis; a glenoid cavity bone inner sleeve of the glenoid cavity prosthesis is arranged in a humeral head hinging groove of the humerus prosthesis; and a bone trabecula structure is arranged on the outer wall of a humerus handle in a coating manner. Through the adoption of the assembly type shoulder joint prosthesis disclosed by the invention, a set of the scapula prosthesis, the glenoid cavity prosthesis and the humerus prosthesis which are assembled in a cooperating manner and are mutually connected and in cooperation is provided, so that the prosthetic replacement requirements of a patient ofwhich the humerus, the glenoid cavity and the scapula are damaged can be met, and relative moving relationship between the scapula and the glenoid cavity of the human body is also practically simulated; and the bone trabecula structure is arranged on the outer wall of the humerus handle in a coating manner, so that the human organism can be quickly and firmly adhered to the prosthesis, and the problem that prosthesis loosening is easy to generate through bone cement, and during polymerization of the bone cement monomer, a large amount of heat is released, and periphery tissue damages are generated are solved.

The invention relates to the technical field of medical prostheses, in particular to a combined femoral stem. The combined femoral stem comprises a stem body, a femoral neck and a filling layer, wherein the stem body is provided with a mounting groove; one end of the femoral neck extends into a mounting groove; the filling layer is stuffed between the femoral neck and the inner wall of the mounting groove, and the filling layer is fixedly connected with the stem body and the femoral neck. According to the combined femoral stem, the stem body and the femoral neck are of a split structure, the femoral neck with different forward inclination angles can be prepared, the combined femoral stem can adapt to wider forward inclination angle changes, the choice of a patient is increased, and besides, compared with an existing integrated femoral stem structure, the production cost can be reduced. The femoral neck and the stem body are connected through the filling layer, so that connection firmness of the femoral neck and the stem body is guaranteed, the problem of fretting abrasion of an existing press-fit type femoral stem is solved, and the problem of prosthesis looseness and failure caused by osteolysis is also solved.

The invention discloses application of Ferrostatin-1 in preparation of a medicine for resisting prosthesis looseness induced by wear particles derived from an artificial joint prosthesis, and research shows that the wear particles of the joint prosthesis can induce excessive accumulation of reactive oxygen species (ROS) in osteoblasts, inhibit the function of an osteoblast cystine/glutamic acid antitransporter (System Xc-), and reduce the ROS removing capability of glutathione peroxidase 4 (GPX4), so that ROS generation and degradation homeostasis are disordered, secondary ferroptosis of osteoblasts is caused, and the balance between osteoclasts and osteoblasts is broken. After the ferroptosis specific inhibitor Ferrostatin-1 is added, the content of the GPX4 in cells is obviously increased, the stimulation of the wear particles to the generation of ROS in the osteoblasts is obviously inhibited, and the ferroptosis of the osteoblasts is reduced. In addition, a mouse skull osteolysis model is established by implanting the CoCrMo nano wear particles under the skin of a mouse skull, effective intervention is applied by intraperitoneal injection of the Ferrostatin-1, and an in-vivo experiment further proves that the Ferrostatin-1 has a remarkable inhibition effect on osteolysis induced by the wear particles.

The invention discloses a manufacturing method of an individualized customized knee joint topological optimization bionic prosthesis based on 3D printing, which relates to the technical field of medical artificial joints. The problem that the manufacturing method is urgently needed to reduce prosthesis looseness or fracture around the prosthesis is solved, and the method comprises the steps: establishing and assembling a tibia model and a knee joint prosthesis model, and performing finite element analysis and topological optimization; carrying out fairing; designing a specific structure of themodel, optimally reserving an internal region by adopting a solid structure, optimally reserving an outer layer region and optimally removing the region by adopting a grid structure, and forming a gradient between the regions; introducing back an assembly state of a tibia model, performing finite element analysis, comparing with a first finite element analysis result, judging whether 3D manufacturing and application are performed or not, and performing topological optimization again if the 3D manufacturing and application cannot be performed. The prosthesis prepared by the invention reduces the problem of prosthesis looseness or prosthesis peripheral fracture, provides space for ligament stop point implantation and internal bone grafting, is light in weight, and is beneficial to bone tissue ingrowth.

The invention discloses a customized bone-like trabecular structure knee joint prosthesis, including a tibia holder and a tibia pad. A tibia medullary space is formed between the tibia holder and thetibia pad. The tibia medullary space is provided with a bone trabecular grid structure. Appearance of an upper end and a lower end of the knee joint prosthesis meets a human body anatomical structureand fits the medullary space. A PEEK material is used to reduce product weight, stress shielding is reduced, and conditions of bone resorption and prosthesis loosening are prevented. The tibia pad component is provided with an induction device, and an adjusting mechanism and a control structure are arranged in the tibia holder. An objective of installing the induction device is that through adjusting pressure between a femoral condyle and the tibia pad by the device, pressure of a gasket, applied by a femoral condyle prosthesis part, is better balanced, so that the inner side and the outer side of bones on a distal femur and a tibia near-end have uniform pressure. Bone loss and prosthesis failure caused by life styles and other factors are eliminated, and the knee joint prosthesis improvesmedium and long term life of a patient prosthesis.

The invention discloses an artificial hip joint with a micro-dynamic function. An artificial implant applied to a hip joint replacement surgery. The artificial hip joint with the micro-dynamic function comprises a neck, a handle body and a columnar spring for flexibly connecting the neck with the handle body. For the artificial hip joint, by utilizing the characteristics of the columnar spring, acting force, generated by movement of a human body, on a thighbone is effectively reduced, and thus the possibility of prosthesis loosening possibly causing surgery failure is reduced or avoided.

The invention discloses a cobalt alloy partitioned bone trabecula single-compartment femoral condyle prosthesis and a preparation method. The preparation method comprises the following steps: by taking cobalt alloy powder as a raw material, performing 3D printing integrated molding to obtain an intermediate product of the cobalt alloy partitioned bone trabecula single-compartment femoral condyle prosthesis, and performing hot isostatic pressing and a deep cooling process to obtain the cobalt alloy partitioned bone trabecula single-compartment femoral condyle prosthesis. The prosthesis comprises a femoral condyle articular surface and an osseointegration surface. Due to the partitioned bone trabecula, micro motion of the prosthesis and a bone interface can be reduced, and the initial stability is achieved; the stress shielding effect of the prosthesis on bone tissues is reduced, the femoral condyle bone tissue stress is uniform, excellent and uniform bone ingrowth performance is achieved, prosthesis looseness caused by osteoporosis after long-term implantation of the prosthesis is avoided, and long-term stability is achieved. Due to 3D printing integrated molding, the bone trabeculaand the entity are high in bonding strength, the bone trabecula does not easily drop, and the service life of the prosthesis is prolonged. The bone trabecula part of the prosthesis has excellent compression resistance; and the entity part releases residual stress, and the plasticity is enhanced.

A knee joint prosthesis structure comprises a thighbone component, a cushion block component, a tibia component and a patella component, the thighbone component is provided with an intercondylar fixing block, the intercondylar fixing block is provided with a protruding part, the inner wall of the thighbone component is provided with a first coating used for bone ingrowth or bone growth, the cushion block component is located between the thighbone component and the tibia component, the outer wall of the lower end of the tibia component is provided with a second coating used for bone growth or bone length, the patella component is located in front of the thighbone component, and the inner wall of the patella component is provided with a third coating used for bone growth or bone length. The knee joint prosthesis structure is a biological type fixed prosthesis structure, various defects and complications caused by bone cement fixation can be avoided, harm to patients and surgical related medical staff due to current bone cement application is reduced, the long-term stability of the prosthesis is improved, the prosthesis loosening rate and the surgical revision rate are reduced, the cost is saved, and the cost is reduced. and the problem of precious medical observation is solved, and great social effect and economic benefit are achieved.

The invention relates to a knee joint system, a tibial prosthesis, a tibial tray prosthesis series and a tibial tray prosthesis group. The tibial tray prosthesis group comprises at least two tibial tray prostheses of different models, wherein each tibial tray prosthesis is provided with a stand column connected with a tibia and a keel; each tibial tray prosthesis is further provided with a first reference surface and a second reference surface; the second reference surface is intersected with the first reference surface; and when the first reference surfaces of the tibial tray prostheses of different models are aligned and the second reference surfaces are aligned, the stand columns of the tibial tray prostheses of different models are overlapped and the keels are overlapped. According tothe tibial tray prosthesis group, the fixing stability of the tibial tray prostheses is improved and the loosening probability of the tibial tray prostheses is reduced. Meanwhile, stand column holes and keel 13 grooves do not need to be formed again so that the operation efficiency is also improved, the operation time is shortened and the infection probability of patients is reduced.

The invention provides application of melatonin to the preparation of a medicine for treating loose periprosthetic chronic inflammation and bone destruction. The chemical structural formula of melatonin is shown in a specification, and the medicine comprises a compound at pharmaceutically effective dose and a pharmaceutically acceptable carrier. According to the application, a novel medicinal prospect of melatonin is explored, a novel medicinal area is developed, the application has an exact effect of prosthesis loosening, and has the purpose of effectively preventing and treating prosthesis loosening caused by wear particles, besides, expression of inflammatory factors can be obviously reduced, inflammatory response caused by the wear particles is reduced, osteoclast activation is restrained, the formation of local new bones after osteolysis is promoted, and bone destruction caused by the wear particles is reduced.

The invention discloses a reference system for rotational positioning of a femoral prosthesis in total knee arthroplasty, namely an inner cortical plane in front of a distal femur, a part of the plane is positioned below an upper incisura of an upper patella of a femoral tackle, the inner side starts from the medial condyle, and the outer side ends at a connecting recess of the medial condyle and the lateral condyle. According to the method, an existing prosthesis rotation positioning reference system is broken through, operability and accuracy of rotation alignment of the femoral prosthesis in total knee arthroplasty are improved, and after a new reference method is applied, postoperative functional recovery of the prosthesis is expected to be enhanced, adverse events such as looseness and infection of the prosthesis are reduced, and the survival rate of the prosthesis is increased.

The invention discloses a 3D printing customized half-ankle joint prosthesis. The 3D printing customized half-ankle joint prosthesis comprises a tibia far-end prosthesis and a liner; the middle of the tibia far-end prosthesis is a circular truncated cone; the lower portion of the circular truncated cone is a supporting section; a bone trabecula structure is arranged on the peripheral surface of the supporting section; a concave opening is formed in the bottom of the supporting section; a lateral ankle part and a medial ankle part are arranged on the two sides of the concave opening respectively; and the liner is connected into the concave opening in the bottom of the supporting section. According to the 3D printing customized half-ankle joint prosthesis in the invention, a monopole mode is adopted; the sclerotin of a patient can be reserved to the maximum degree; the risks of prosthesis loosening and infection are small; according to the invention, the tibia far-end prosthesis of a solid structure is adopted; the overall mechanical strength is guaranteed; the bone trabecula structure has the good bone ingrowth and thigh crawling capacity; the stability of the prosthesis is improved; the liner can buffer the impact between the prosthesis and the talus of a human body in the movement process; and the biomechanical requirement is met.

The invention belongs to the technical field of medical prostheses, and discloses an acetabular cup prosthesis. The acetabular cup prosthesis comprises a prosthesis body and a bone fusion layer whichis fixedly attached to the outer surface of the prosthesis body, wherein the bone fusion layer comprises a glassy carbon matrix which is constructed into a spatial three-dimensional structure, and a tantalum metal layer which is attached to the surface of the glassy carbon matrix; the glassy carbon matrix comprises a plurality of glassy carbon wires and a plurality of pores which are formed by connecting the plurality of glassy carbon wires in a staggered manner; and the pores communicate with one another and are different in diameter. The acetabular cup prosthesis has the advantages of facilitating bone ingrowth, providing relatively high friction force, reducing stress shielding and the like, so that the stability of the prosthesis after implantation is improved, and the phenomena of prosthesis loosening, dislocation, fracture and the like are reduced.