115results about "Cytochromes" patented technology

The present invention is directed to novel compositions and methods utilizing delivery agents comprising protein cages, medical imaging agents and therapeutic agents.

The present disclosure provides photoactive polypeptides. A subject photoactive polypeptide is useful in a variety of applications, which are also provided.

The present invention relates to cupredoxin and cytochrome and their use, separately or together, to inhibit the spread of parasitemia in mammalian red blood cells and other tissues infected by the malaria parasite, and in particular the parasitemia of human red blood cells by P. falciparum. The invention provides isolated peptides that are variants, derivatives or structural equivalents of cupredoxins or cytochrome c, and compositions comprising cupredoxins and / or cytochrome c, or variants, derivatives or structural equivalents thereof that are useful for treating or preventing malaria infection in mammals. Further, the invention provides methods to treat mammalian patients to prevent or inhibit the growth of malarial infection in mammals. The invention also provides methods to prevent the growth of malaria infection in insect vectors.

Cellular models for diseases of eyes, methods and compositions for treating diseases in eyes are provided.

Expression systems and methods for the expression of functional membrane polypeptides such as human cytochrome b5 are provided. The systems include recombinant expression vectors capable of expressing soluble fusion proteins that include a solubilizing agent, a linker, and a membrane polypeptide, as well as one or more cleavers, e.g. proteases, capable of cleaving the linker to release the membrane polypeptide. When the fusion protein is expressed, the linker is cleaved by the cleaver to allow association of the membrane polypeptide with a membrane.

The invention relates to application of herbicide-tolerance protein. A method for controlling weeds comprises the following steps: applying a herbicide with an effective dosage of tribenuron-methyl to a plant growing environment with at least one transgenic plant, wherein the transgenic plant comprises a nucleotide sequence of encoded thifensulfuron methyl hydrolytic enzyme in a genome, and the transgenic plant has alleviated plant damage and / or increased plant yield when being compared with other plants without the nucleotide sequence of the encoded thifensulfuron methyl hydrolytic enzyme. The invention discloses that the thifensulfuron methyl hydrolytic enzyme has relatively high tolerance to a tribenuron-methyl herbicide for a first time, plants with the nucleotide sequence of the encoded thifensulfuron methyl hydrolytic enzyme are relatively high in tolerance to the tribenuron-methyl herbicide, and the land concentration of at least 1 time can be tolerated. Therefore, the herbicide-tolerance protein is wide in application prospect for plants.

The invention relate to application of herbicide tolerance protein. A weed control method includes the step of applying herbicide with an effective dosage of sulfometuron methyl to the plant growth environment of at least one transgenic plant, wherein genomes of the transgenic plants have nucleotide sequences for encoding thifensulfuron methyl hydrolase, and the transgenic plants have weak plant damage and / or increased plant yield compared with other plants without nucleotide sequences for encoding thifensulfuron methyl hydrolase. Thifensulfuron methyl hydrolase is disclosed for the first time and presents high tolerance for the sulfometuron methyl herbicide, and the plants with nucleotide sequences for encoding thifensulfuron methyl hydrolase have strong tolerance for the sulfometuron methyl herbicide and at least can bear 1-fold field concentration, and therefore wide application prospects are achieved for plants.