The invention relates to the technical field of 
drug detection, and discloses an 
allopurinol quality detection method, which comprises: S1, preparing raw materials: 30 pieces of 
allopurinol tablets, abalance, a screen, a 
mortar, a 100 ml measuring flask, 30 ml of NaOH, a 500 ml measuring flask, 200 ml of 
hydrochloric acid solution, and a stirring rod; S2, carrying out 
grinding and filtering: weighing 20 pieces of 
allopurinol tablets by using the balance, recording the 
mass, carrying out 
grinding by using the 
mortar and filtering by using the screen; and S3, carrying out 
dissolution. Accordingto the method disclosed by the invention, allopurinol and other related substances, namely impurities, in the allopurinol 
powder sample to be detected can be effectively separated and detected; the 
operability is strong, the specificity of the detection method is strong, the sufficient reaction of allopurinol 
powder and NaOH is promoted, and the time is saved; and the liquid 
medicine adhered to the surface of the stirring rod can be flushed away, and in addition, the liquid splashing can be prevented from influencing the concentration of substances in the liquid 
medicine, and the influence onthe detection result is avoided, so that the detection precision is improved.