The invention relates to a device for production of a packaging hose and a use method of the device. The device comprises a bracket, a rotary disc arranged on the bracket, a printing core arranged on the rotary disc, a hose feeding mechanism, a sealing mechanism, a labeling mechanism, a capping mechanism, a cap fastening mechanism, a blowing and discharging mechanism, a discharge transfer belt, a hose cutting mechanism, a waste discharging mechanism and a circuit control system. The hose feeding mechanism, the sealing mechanism, the labeling mechanism, the capping mechanism/the hose cutting mechanism, the blowing and discharging mechanism, the discharge transfer belt and the waste discharging mechanism are arranged orderly along the circumferential direction of the rotary disc and are controlled by the circuit control system. The device has the multifunction of integrating hose feeding, sealing, labeling, capping, hose cutting, cap fastening, hose discharging, waste discharging and the like, avoids the turnover among cockamamie steps, is beneficial to saving manpower cost and can improve the production efficiency.